Homeopathy最新文献

{"title":"Efficacy of Individualized Homeopathic Medicinal Products in LM Potencies in Cancer-Related Fatigue: Protocol for a Series of N-of-1 Trials, with Meta-analysis of Individual Patient Data.","authors":"Shubhamoy Ghosh, Mahejabeen Siddique, Koushik Chatterjee, Rajat K Pal, Sk Monsur Alam, Indrani Halder, Suman Chandra, Ayan Midya, Subhranil Saha","doi":"10.1055/a-2547-9741","DOIUrl":"10.1055/a-2547-9741","url":null,"abstract":"<p><p>Cancer-related fatigue (CRF) poses a significant challenge in cancer care and affects the quality of life of many patients. Despite the prevalence and impact of the condition, identifying effective therapies remains a challenge. Non-pharmacological remedies, such as complementary therapies including homeopathy, are under-researched. A clinical trial with n-of-1 design has therefore been planned to evaluate the potential of individualized homeopathic medicinal products (IHMPs) in the management of CRF.A series of double-blind, randomized, placebo-controlled, n-of-1 trials will be conducted. Each participant will undergo three rounds of two intervention phases in a randomly determined order. The study will be performed at the Oncology Outpatient Department of D. N. De Homoeopathic Medical College and Hospital. Participants with CRF who meet pre-defined eligibility requirements will be enrolled. The FACIT-F sub-scale is the primary outcome measure; Short Form-36 and the Wu Cancer Fatigue Scale are the secondary outcomes. All outcomes will be measured at baseline, on day 7 and then every 10 days for 2 months. The sample size will be the number of patients who can be recruited during the 18-month period of the trial. The Numerical Rating Scale (0-10) measuring fatigue severity will be used in screening and preliminary evaluation of the degree of fatigue. Comprehensive blood tests to evaluate various physiological factors related to CRF will also be performed. An assessment of the effect of the IHMPs will be obtained per individual and by aggregating the data of all participants via meta-analysis.The results of our study will clarify the possible therapeutic effects of IHMPs for patients with CRF, as well as improve our understanding of the n-of-1 study design as it is applied to homeopathy research.Clinical Trials Registry-India: CTRI/2024/03/064438.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to Assess Variation in Homeopathic Prognostic Factor Research?","authors":"Lex Rutten, José E Eizayaga, Harleen Kaur, Shalini Rao, Anurag Bajpai, Chetna Deep Lamba, Jyoti Sachdeva, Vinitha E R, Sonia Raizada, Rompicherla Gr Kiranmayee, Bondarkar Rajashekhar, Chittranjan Kundu, Vaishali Shinde, Sujata Choudhury, Amulya Ratan Sahoo, Ratan Chandra Shil, Abhijit Chakma, Nidhi Mahajan, Alok Mishra, Anil Khurana, Praveen Oberai, Raj K Manchanda","doi":"10.1055/a-2544-2807","DOIUrl":"https://doi.org/10.1055/a-2544-2807","url":null,"abstract":"<p><p>We need to classify the outcome of prognostic factor research (PFR), especially regarding polar symptoms (PS) - symptoms with opposite values such as amelioration/desire and aggravation/aversion. For instance, in a data collection project 22.9% of the patients responding well to <i>Arsenicum album (Ars)</i> had 'Desire salt' and 5.7% 'Aversion salt'. Can such differences be explained by statistical variation?Frequency distributions of PS were analysed and compared with previous research to reveal differences. Cumulative binomial probability (CBP) and 95% confidence intervals (95% CIs) were calculated to assess the influence of statistical variation on the difference between the medicine population and the remainder of the population and the difference between opposite poles. CBP and 95% CI were compared regarding usefulness for daily practice. 95% CIs were used to calibrate the CBP. Corroboration by comparable symptoms was also used to validate outcomes.In several PS, there was asymmetry between opposite poles and a difference compared with previous research. The most probable cause was using questionnaires, disregarding clinical expertise. This results in asymmetrical frequency distributions when symptoms are common and the criterion 'more than average' was ignored. This, in turn, results in relatively low likelihood ratios (LRs) caused by a 'ceiling effect'.The CBP correlates with 95% CI, indicates the amount of overlap of 95% CIs, and is useful to classify the statistical certainty of PFR outcome. Based on CBP and difference of CBP for opposite symptoms, LR outcome was classified as statistically 'Certain', 'Probable', 'Possible' or 'Questionable'. Cut-offs between classes were based on expert estimates. Part of the outcome could be corroborated by the outcome of similar or opposite symptoms.Asymmetry of symptom frequency distributions in PS can be caused by practitioners not using their expert knowledge while assessing symptoms. A classification of reliability of data based on cumulative binomial chance is more informative and is better understood by experts in homeopathy. Nevertheless, classification of reliability remains partly subjective. Corroboration of outcome and clinical judgment are indispensable for estimating clinical validity of PFR outcomes. Practitioners and researchers participating in PFR need training in statistics and homeopathy respectively.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Homeoprophylactic Arsenicum album 30c on COVID-19 Vaccine-related Adverse Events: A Combined Retrospective-Prospective Cohort Study.","authors":"Debadatta Nayak, Ruchika Bhalla, Lovepreet Kaur, Divya Bansal, Smita Singh, Navita Bagdi, James Michael, Abhishek Chaudhuri, Lalit Tyagi, Bhavna Makhija, Shikha Madaan, Deblina Das, Indu Shukla, Srimonti Sanyal, Khan Sheeba Saleem, Ajay Yadav","doi":"10.1055/a-2512-9763","DOIUrl":"https://doi.org/10.1055/a-2512-9763","url":null,"abstract":"<p><strong>Objective: </strong> <i>Arsenicum album</i> 30C (<i>AA30</i>) was recommended by the Government of India for the prevention of coronavirus infection. In the wake of the reporting of COVID-19 vaccine-related adverse events (AEs) and consequent vaccine hesitancy, this study was undertaken to assess the impact of homeo-prophylactic <i>AA30</i> on COVID-19 vaccine-related AEs.</p><p><strong>Methods: </strong> This was a combined retrospective-prospective cohort study that included participants who had been enrolled in an ongoing prospective, parallel cohort study being conducted in urban slums of New Delhi and who had received either or both doses of the COVID-19 vaccine. The reporting of COVID-19 vaccine-related AEs was compared between a cohort that had been receiving homeopathic <i>AA30</i> as a prophylactic for influenza-like/COVID-like illness with one in which no homeopathic intervention was provided.</p><p><strong>Results: </strong> A total of 1,737 participants who received either or both doses of vaccination for COVID-19 were included in the study, out of whom 436 participants were from the medicine cohort (MC) and 1,301 were from the control cohort (CC). Overall odds of developing AEs after either dose of COVID-19 vaccine in MC as compared with CC was found to be statistically significantly lower (overall crude OR = 0.29, 95% confidence interval [CI] = 0.23 to 0.37; <i>p</i> = 0.0001). The adjusted OR after accounting for age, sex, co-morbidities and vaccine type was 0.30 (95% CI = 0.24 to 0.39; <i>p</i> = 0.0001). The protective effect of the medicine against post-vaccination AEs was evident after the first dose as well as after the second dose, with overall crude OR being 0.37 (95% CI = 0.29 to 0.48; <i>p</i> = 0.0001) and 0.28 (95% CI = 0.19 to 0.41; <i>p</i> = 0.0001) respectively.</p><p><strong>Conclusion: </strong> Prior use of the homeopathic medicine <i>AA30</i> was able to significantly reduce COVID-19 vaccine-related AEs.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facilitating Healing in Diabetic Foot Ulcers Using Homeopathy in a Multi-Disciplinary Integrative Approach: Two Evidence-Based Case Reports.","authors":"Hima Bindu Ponnam","doi":"10.1055/s-0044-1779723","DOIUrl":"10.1055/s-0044-1779723","url":null,"abstract":"<p><strong>Background: </strong> A rising incidence of diabetic foot ulcers (DFUs) in India has escalated the rate of lower limb amputations in the country. The present study aims to evaluate the potential healing properties of homeopathic medicines as a part of the integrative management of DFUs through two evidence-based case reports.</p><p><strong>Methods: </strong> Two patients with DFUs, identified as Wagner grade 2, having had diabetes for 12 years, were treated with individualized homeopathic medicine within a multi-disciplinary approach. Both cases were on oral hypoglycemic agents for managing blood sugar, continued their diabetic medication, and were advised to use regular wound dressings. The DFUs were assessed using the Pressure Ulcer Scale for Healing (PUSH) score at baseline and every 4 weeks until complete wound healing. Neuropathic changes were evaluated by the 10g monofilament tactile test, and the Modified Naranjo Criteria for Homeopathy-Causal Attribution Inventory (MONARCH) tool was used to assess the likelihood of there being a causal relationship between clinical improvement and the homeopathic intervention.</p><p><strong>Results: </strong> The DFUs showed healing within 12 weeks, with a significant improvement in the PUSH score, though there was no change in tactile sensation as assessed by the monofilament test. The MONARCH tool yielded +9 in both cases, indicating the likelihood of a causal relationship between the clinical outcome and homeopathic intervention. The homeopathic medicines <i>Arsenicum album</i> and <i>Lachesis</i> respectively were found useful by each patient.</p><p><strong>Conclusion: </strong> Homeopathy appeared beneficial in facilitating the early healing of DFUs within a multi-disciplinary integrative approach.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":"130-137"},"PeriodicalIF":1.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140039205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protocol Standardization of Homeopathic Medicines' Preparation and Dosing for Experimental Model Systems In Vitro.","authors":"Nilanjana Basu, Simran Tandon","doi":"10.1055/s-0044-1786513","DOIUrl":"10.1055/s-0044-1786513","url":null,"abstract":"","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":"142-144"},"PeriodicalIF":1.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140916435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidimensional Outcome Parameters in a Cress Seedling-CuCl2 Crystallization Assay to Corroborate Specific Effects of Stannum metallicum 30x Compared to Lactose 30x.","authors":"Paul Doesburg, Jens-Otto Andersen, Claudia Scherr, Maria Olga Kokornaczyk, Stephan Baumgartner","doi":"10.1055/s-0044-1785517","DOIUrl":"10.1055/s-0044-1785517","url":null,"abstract":"<p><strong>Background: </strong> Previously we developed a test system which yielded highly significant evidence for specific effects of a <i>Stannum metallicum</i> 30x preparation in a multi-center replication trial. This test system is based on cress seed germination in homeopathic or control samples, CuCl₂ crystallization of the cress extract, and subsequent digital textural image analysis of the resulting crystallization patterns.</p><p><strong>Objectives: </strong> The current study aimed to investigate whether three novel outcome parameters could further corroborate and possibly characterize the specific effects of <i>Stannum metallicum</i> 30x.</p><p><strong>Methods: </strong> To this end, (1) cress seedling length, (2) a second texture analysis parameter, entropy and (3) the local connected fractal dimension (LCFD) of crystallization patterns as a measure of complexity were considered. The stability of the experimental setup was monitored throughout the entire investigation with systematic negative control (SNC) experiments.</p><p><strong>Results: </strong> Cress length and entropy revealed a time-modulated potency treatment effect, in the absence of a significant main treatment effect. This indicated that the effect of the potency treatment varied significantly across the different experimental days. LCFD yielded a highly significant potency treatment effect. In addition, a significant interaction of treatment with experimental day seems to indicate a modulation of this effect. No significant effects were observed in any of the evaluations of the SNC experiments, indicative of a stable experimental setup and a reliable and specific treatment effect. Neither significant nor strong correlations were found between the four parameters, indicating that they reflect different effects of <i>Stannum metallicum</i> 30x on the organism treated.</p><p><strong>Conclusion: </strong> This quadruple characterization of the biological effects of <i>Stannum metallicum</i> 30x provides an unprecedented opportunity for basic homeopathy research into, among others, the presumed specificity of homeopathic preparations.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":"117-129"},"PeriodicalIF":1.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020510/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141310615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Homeopathy as a Means to Improve Quality of Life.","authors":"Fernanda Maria Simões da Costa Fujino, Ana Paula Ribeiro, Jane de Eston Armond, Patrícia Colombo de Souza","doi":"10.1055/s-0044-1785521","DOIUrl":"10.1055/s-0044-1785521","url":null,"abstract":"<p><p>Quality of life is a fundamental aspect of good health and differs from person to person, highlighting the importance of individualisation, which is one of the principles of homeopathic doctrine. Homeopathy aligns with the principles of the Brazilian public health system, reflecting the latter's ethos of universality, accessibility, care coordination, and comprehensiveness, offering a whole-person approach to health care. Homeopathy's individualised approach and expanded view of the health-disease process, with emphasis on healthy lifestyle guidance, contributes to the promotion of individual good health and quality of life. These attributes of homeopathy make it a valuable therapeutic option, with relevance to the health service of Brazil as well as to that of other countries across the world.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":"138-141"},"PeriodicalIF":1.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141160338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Patient Population at Homeopathic Outpatient Clinics across India: A Clinical Data Collection Study.","authors":"Harleen Kaur, Surbhi Jain, Daisy Katarmal, Jyoti Sachdeva, Hima Bindu Ponnam, K C Muraleedharan, Suraia Parveen, Sonia Raizada, Liyi Karso, Renu Bala, Amit Srivastava, Vaishali Shinde, Sunil Ramteke, Gurudev Choubey, Chittaranjan Kundu, Vinitha E Ramanan, Tejaswini Patole, Ranjit Sonny, Baidurjya Bhattacharjee, Ravi Kumar Sardarla, Ramesh S Bawaskar, G R C Reddy, Kumar Keshav Avinash, Santosh Tamang, Akhyaya Kumar Prusty, Madhumita Sadhukhan, Artemis Maglara, Anastasia Garoufali, Michael Stassinopoulos, Theodoros Lilas, Lefteris Tapakis, Anil Khurana, Raj K Manchanda","doi":"10.1055/s-0044-1782221","DOIUrl":"10.1055/s-0044-1782221","url":null,"abstract":"<p><strong>Background: </strong> Even though several initiatives have been undertaken in different locations worldwide to collect clinical data in homeopathy, it is important to further investigate these aspects in the context of health care in India.</p><p><strong>Objective: </strong> The study aimed to gather and analyze patients' clinical data and to derive insights into homeopathic treatment using an internet-based software program for data storage, retrieval and repertorization.</p><p><strong>Methods: </strong> A multi-center observational study was conducted across 14 homeopathy outpatient clinics in India that are affiliated with the Central Council for Research in Homoeopathy (CCRH). Patient symptoms and demographic details were documented anonymously, and prescriptions were guided by repertorial suggestions from the Vithoulkas Compass software. During follow-up visits, treatment outcome was also recorded using an online assessment form. A retrospective analysis of data on patients' demographics, follow-up visits, morbidity (International Classification of Diseases 11th Revision), rubrics used, prescribed medicines and the level of improvement was achieved using Microsoft Excel-generated pivot tables.</p><p><strong>Results: </strong> Throughout the study duration of one year a total of 2,811 patients attended the 14 outpatient clinics, of whom 2,468 were new patients with a total of 2,172 initial homeopathic prescription entries. Across the study, there were 3,491 prescriptions and 1,628 follow-up consultations for 868 follow-up patients, all of which data were thoroughly analyzed. The highest frequency of patients was in the 20-49 age group, and a higher proportion of the patients overall was female. Musculoskeletal, dermatological and respiratory complaints were the most frequently reported. The rubrics \"Desire for sweets\" and \"Desire for spices\" emerged as the most commonly used in the repertorizations. Further, <i>Sulphur</i> stood out as the most commonly prescribed medicine overall. With homeopathic treatment, some degree of clinical improvement was reported in 86% of the follow-up cases.</p><p><strong>Conclusion: </strong> Homeopathy is prescribed in CCRH outpatient clinics for a wide range of ailments in people across India, with at least some clinical improvement noted in a high proportion of those patients. The large-scale systematic data collection in these clinics has provided clear insights into the use and clinical value of homeopathy in India, with the potential to build a substantive nationwide data inventory over time.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":"74-84"},"PeriodicalIF":1.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141183409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Homeopathy on a Grand Scale.","authors":"Robert T Mathie","doi":"10.1055/a-2550-8641","DOIUrl":"https://doi.org/10.1055/a-2550-8641","url":null,"abstract":"","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":"114 2","pages":"73"},"PeriodicalIF":1.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of COVID-19 Complications during a Program of Homeopathic Camphora Officinalis Distribution to City Populations of Santa Catarina, Brazil: An Ecological Study.","authors":"Edgard Costa de Vilhena, Nicolle R Telles Coutracos, Ednar N Coimbra, Karen Berenice Denez, Adriana Passos Oliveira, Carla Holandino, Vânia Emerich Bucco de Campos, Giovanni Bravin Peres, Leoni Villano Bonamin","doi":"10.1055/s-0044-1786511","DOIUrl":"10.1055/s-0044-1786511","url":null,"abstract":"<p><strong>Background: </strong> Coronavirus disease 2019 (COVID-19), a disease caused by the SARS-CoV-2 coronavirus, was declared a pandemic in March 2020, posing significant challenges globally. Homeopathy has historical relevance in epidemic management. In response, the government of the state of Santa Catarina, Brazil, distributed <i>Camphora</i> 1M as a potential prophylactic intervention for COVID-19.</p><p><strong>Objective: </strong> This study aimed to investigate the possible effects of <i>Camphora</i> 1M as an adjunctive prophylactic measure in managing COVID-19, focusing on mortality and hospitalization rates, during the period April 28 to July 31, 2020, within designated COVID-19 in-patient units in Santa Catarina.</p><p><strong>Methods: </strong> An ecological study design was applied to this epidemiological research. Five case municipalities (Itajaí, Atalanta, Entre Rios, Rio do Campo, Trombudo Central) were compared with five control municipalities (São José, Galvão, Pedras Grandes, Grão-Pará, Ascurra).</p><p><strong>Results: </strong> No statistically significant differences were observed in predictor variables between municipalities that received <i>Camphora</i> 1M and the respective controls. Similarly, no statistically significant differences were observed in outcomes: deaths (<i>p</i> = 0.879), hospitalized cases (<i>p</i> = 0.537), daily ward admissions (<i>p</i> = 0.730) and ICU admissions (<i>p</i> = 0.072).</p><p><strong>Conclusion: </strong> For the first wave of the pandemic in the state of Santa Catarina, Brazil, city-wide distribution of <i>Camphora</i> 1M was not associated with reduced numbers, severity or mortality among the population hospitalized in designated public hospitals for COVID-19.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":"85-94"},"PeriodicalIF":1.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}