Homeopathy最新文献

{"title":"Assessment of Likelihood Ratio of the Medicines Enlisted under the Rubric \"Pain, Knee, Motion, Amelioration\" in the Extremities Chapter of Kent's Repertory.","authors":"Urmi Roy, Rajat K Pal, Subhranil Saha, Sk Monsur Alam, Munmun Koley, Raghubir Gole, Sumana Sengupta, Quamar Sultana, Usashi Nag, Mousumi Koley, Shifa Hashmi, Ayan Midya, Doly Chakraborty, Swarup Biswas, Subhasish Ganguly, Lex Rutten","doi":"10.1055/a-2515-9950","DOIUrl":"https://doi.org/10.1055/a-2515-9950","url":null,"abstract":"<p><strong>Background: </strong> \"Pain, Knee, Motion, Amelioration\" in the Extremities chapter of Kent's repertory with 20 enlisted medicines is one of the most frequently encountered rubrics in homeopathy but has not been evaluated systematically. Bayesian statistics resulting in the likelihood ratio (LR) could offer a better evaluation of the enlisted medicines as well as the eligibility of other medicines.</p><p><strong>Methods: </strong> An analytical, epidemiological, longitudinal outcome study was conducted in different outpatient departments of D.N. De Homoeopathic Medical College and Hospital, Kolkata, on 1,204 patients over 18 months using ORIDL (Outcome Related to Impact on Daily Living), whose scale ranges from +4 to -4. Results were documented during each follow-up, continuing until the most recent visit at an average of 3 months. The LRs were reported with their corresponding 95% confidence intervals (CIs).</p><p><strong>Results: </strong> Analysis included 1,204 cases with 20 enlisted medicines and 37 not enlisted homeopathic medicines. The prevalence of the rubric \"Pain, Knee, Motion, Amelioration\" was 18.8%. Among the enlisted ones, the medicines having LR ≥ 1.5 were <i>Calcarea carbonicum</i> LR(+) 1.7 (95% CI: 0.8 to 3.5) and <i>Rhus toxicodendron</i> LR(+) 2.3 (95% CI: 1.7 to 3.1). Some medicines with LR ≥ 1.5 that were not previously enlisted in the rubric were <i>Arnica montana</i> LR(+) 2.0 (95% CI: 0.9 to 4.3), <i>Carbo vegetabilis</i> LR(+) 1.8 (95% CI: 0.8 to 4.0), and <i>Staphysagria macrosperma</i> LR(+) 1.5 (95% CI: 0.5 to 5.0). Overall, the findings corroborated the medicines' listing under the rubric in Kent's repertory.</p><p><strong>Conclusion: </strong> There was substantial evidence to link some of the enlisted medicines with the said rubric. Additional research involving a larger population is needed to address the potential confirmation bias.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of Pantaneira Breed Cows on Pasture Supplemented with Homeopathic Additives and Yeast.","authors":"Leandra da Silva Florentino, Evellyn Richelly Ferreira da Silva, Mariana Santos, Daniele Portela de Oliveira Torgan, Fernando Miranda de Vargas Júnior, Dirce Ferreira Luz, Dalton Mendes de Oliveira, Marcus Vinicius Morais de Oliveira","doi":"10.1055/s-0044-1800966","DOIUrl":"10.1055/s-0044-1800966","url":null,"abstract":"<p><p>To improve the nutritional efficiency of ruminants and promote well-being in a natural and effective manner, the use of additives such as homeopathic products and yeast has been increasingly incorporated into diets, especially in grazing systems.To evaluate the effects of homeopathic products and yeast on the performance of Pantaneira cows maintained in rotational grazing on Mombaça grass in the Pantanal, Brazil.Sixty cows were assigned to a completely randomized design with four treatments and 15 replicates. The treatments were: CTL: control (without additives); HOM: homeopathic (4 g/kg Entero 100, 4 g/kg Figotonus, and 4 g/kg Convert H); YEA: yeast (24 g/kg <i>Saccharomyces cerevisiae</i>); and HY: homeopathic + yeast (4 g/kg Entero 100, 4 g/kg Figotonus, 4 g/kg Convert H + 24 g/kg <i>S. cerevisiae</i>). The variables measured included forage and supplement intake, diet digestibility, weight gain, and feed conversion. Data were subjected to analysis of variance (ANOVA), followed by Tukey and Duncan tests, with a significance level set at 5%.Cows in the HY treatment group showed higher average daily gains and better feed conversion compared to the CTL treatment (<i>p</i> ≤ 0.05). They exhibited higher digestibility of dry matter, crude protein, neutral detergent fiber, acid detergent fiber, and ether extract, as well as higher levels of total digestible nutrients and digestible energy (<i>p</i> ≤ 0.05).The inclusion of 4 g/kg Entero 100, 4 g/kg Figotonus, 4 g/kg Convert H, and 24 g/kg <i>S. cerevisiae</i> improved nutrient digestibility, body weight gain and feed conversion in Pantaneira cows.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143648365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Scientific Doctor.","authors":"Lex Rutten","doi":"10.1055/s-0045-1802339","DOIUrl":"10.1055/s-0045-1802339","url":null,"abstract":"<p><p>Medical professionals do not sufficiently realise how much scientific responsibility they take when certified science fails. They must make the best choice for the individual patient based on their own experience and that of their colleagues. This 'next best choice' requires basic knowledge about heuristic bias and statistics. The best solutions based on experience could then be classified according to their reliability and expected effectiveness. This requires probability and conditional probability calculations that result in Bayesian updating of the likelihood of individual cures. Practitioners could have considerable influence on medical decision-making by applying Bayesian probability. The high quality and large quantity of combined experience can ultimately be translated into treatment algorithms, to be tested in daily practice. To achieve this, we need better scientific training of practitioners and a suitable infrastructure of the professional community.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143648366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Eupatorium perfoliatum 30C in Preventing Dengue Fever: A Critical Appraisal.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.1055/s-0044-1801389","DOIUrl":"https://doi.org/10.1055/s-0044-1801389","url":null,"abstract":"","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143500637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to the Letter to the Editor: Effectiveness of Eupatorium perfoliatum 30C in Preventing Dengue Fever: A Critical Appraisal.","authors":"Debadatta Nayak, Lovepreet Kaur, Rupali Bhalerao, Karanpreet Nahar, Hanuman Ram, Pawan Sharma, Ankit Gupta, Smita Singh, Anil Khurana, Raj K Manchanda","doi":"10.1055/s-0044-1801390","DOIUrl":"https://doi.org/10.1055/s-0044-1801390","url":null,"abstract":"","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143500639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Method for Estimating the Sensitivity of Homeopathic Repertories.","authors":"Kurian Poruthukaren, Jeenu Joseph, Theresa Mathews","doi":"10.1055/s-0044-1801298","DOIUrl":"https://doi.org/10.1055/s-0044-1801298","url":null,"abstract":"<p><strong>Background: </strong> Homeopathic repertories are essential tools in remedy diagnosis, helping practitioners match patient symptoms with those produced by remedies. However, repertories often need to be revised due to omissions, misinterpretations, and incomplete representation of remedy symptoms. Despite their importance, the sensitivity of repertories - their ability to correctly identify remedies based on corresponding rubrics - has never been systematically estimated. Addressing this gap is crucial to ensuring repertories' accuracy, reliability and validity in homeopathic practice.</p><p><strong>Methods: </strong> We adopted the sensitivity formula used in medical diagnostics, where true positives indicate correct remedy identification and false negatives represent failures. This method was applied to Kent's repertory for <i>Allium cepa</i> using symptoms from Hering's <i>Guiding Symptoms of our Materia Medica</i>. We extracted the rubrics and identified the non-representing rubrics and omissions. We created a Python script that generated combinations of rubrics based on Allen's 'three-legged stool rule'. We calculated the sensitivity as the ratio of true positives to total combinations.</p><p><strong>Results: </strong> Of the 525 symptoms of <i>Allium cepa</i>, we extracted 364 rubrics from Kent's repertory, with 161 symptoms omitted. Among the extracted rubrics, 111 failed to represent <i>Allium cepa</i>. The Python script generated 23,979,550 combinations, of which 21,050,260 (87.78%) were false negatives, and 2,929,290 (12.2%) were true positives.</p><p><strong>Conclusion: </strong> The sensitivity of Kent's repertory for <i>Allium cepa</i> was estimated as 12.2%. The method can thus effectively estimate the sensitivity for given remedies in a homeopathic repertory. Applying this method to other remedies would enhance a repertory's diagnostic accuracy and could lead to the development of artificial intelligence-driven tools for repertorial analysis.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Environmental Homeopathy: Homeopathic Potencies Regulate the Growth and Toxicity of Raphidiopsis raciborskii (Cyanobacteria) and can be Tracked Physico-Chemically. Part 2: Physico-chemical Results.","authors":"Suham Nowrooz Mohammad, Andreia Adelaide G Pinto, Rodrigo Augusto da Silva, Ivana Barbosa Suffredini, Alexander L Tournier, Steven J Cartwright, João Sarkis Yunes, Leoni V Bonamin","doi":"10.1055/s-0044-1780527","DOIUrl":"10.1055/s-0044-1780527","url":null,"abstract":"<p><strong>Introduction: </strong> The control of cyanobacterial toxicity and growth by homeopathic potencies was described in Part 1 of this two-part report. Here, a parallel approach characterized the physico-chemical features of the potencies used and the liquid media treated with them, correlating these results with their respective biological effects.</p><p><strong>Objectives: </strong> Our objective was to establish if physico-chemical parameters can track homeopathic potencies in seawater or artificial seawater medium (ASM)-1 and to discover whether these parameters correlate with previously described biological effects.</p><p><strong>Method: </strong> <i>Artemia franciscana</i> (brine shrimp) cysts were cultivated in seawater challenged with <i>Raphidiopsis raciborskii</i> extract and treated with different homeopathic potencies chosen from a screening process. Cultures of <i>R. raciborskii</i> maintained in ASM-1 were also treated with previously screened homeopathic potencies, and their growth was monitored as a function of time. The physico-chemical properties of the treated media (seawater or ASM-1) were evaluated by their interaction with solvatochromic dyes and changes in pH, conductivity and temperature.</p><p><strong>Results: </strong> Coumarin 7 was found to be a marker for <i>Nitric acidum</i> 6cH and Isotherapic (<i>R. raciborskii</i> extract) 200cH in seawater (analysis of variance [ANOVA], <i>p</i> = 0.0015). Nile red was found to be a marker for <i>Nitric acidum</i> 200cH and <i>Mercurius solubilis</i> 30cH in ASM-1 (ANOVA, <i>p</i> ≤ 0.001). An increase in pH of ASM-1 and endothermic effects were observed after these treatments (two-way ANOVA, <i>p</i> = 0.0001). Seawater and ASM-1 to which potencies had been added were also subjected to a constant unidirectional 2,400 Gauss static magnetic field and found to have enhanced effects on the solvatochromic dyes tested.</p><p><strong>Conclusion: </strong> Homeopathic potencies were specifically traceable in aqueous media using solvatochromic dyes, especially when the samples were subjected to a magnetic field. Results from monitoring other physical parameters, such as pH and temperature, were less specific in relation to potency tracking. However, potency-induced endothermic effects might provide valuable thermodynamic data relating to the nature of potencies.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":"18-31"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contributing Reviewers in 2024.","authors":"","doi":"10.1055/s-0044-1801804","DOIUrl":"https://doi.org/10.1055/s-0044-1801804","url":null,"abstract":"","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":"114 1","pages":"i-ii"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Benefits and Challenges of Publishing Diverse Studies in Homeopathy.","authors":"Angelina J Mosley, Robert T Mathie","doi":"10.1055/s-0044-1800866","DOIUrl":"https://doi.org/10.1055/s-0044-1800866","url":null,"abstract":"","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":"114 1","pages":"1-2"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultradiluted Homeopathic Medicines Cause Apoptosis in RPMI-8226 Multiple Myeloma Cells in vitro: a Pilot Study.","authors":"Buket Altinok Gunes, Murat Kilic, Tulin Ozkan, Nurbanu Gonulkirmaz, Nurcihan Guven, Asuman Sunguroglu","doi":"10.1055/s-0044-1786035","DOIUrl":"10.1055/s-0044-1786035","url":null,"abstract":"<p><strong>Background: </strong> Multiple myeloma (MM) is the second most common type of cancer among hematological malignancies and is difficult to treat. Although controversial in nature, homeopathy's effects have been tested on a wide range of cancer cell types <i>in vitro</i>, as well as clinically. However, homeopathic medicines have yet to be tested in MM cells. In this preliminary study, we investigated the effects of <i>Arsenicum album</i>, <i>Hecla lava</i>, <i>Carcinosinum</i> and <i>Carboneum sulphuratum</i> 200C on a human MM cell line.</p><p><strong>Methods: </strong> The RPMI-8226 MM cell line was cultured <i>in vitro</i> for up to 96 hours and treated with each of four homeopathic preparations. The spectrophotometric 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, flow cytometric Annexin V-PE/7-actinomycin D (7-AAD) and propidium iodide (PI) staining were each used to examine cell viability, apoptosis and cell cycle, respectively.</p><p><strong>Results: </strong> The MTT assay showed that all four homeopathic preparations reduced cell viability over time when compared to the control group cells, especially at 72 and 96 hours whereby only 50% of cells remained viable. Similarly, after 96 hours of treatment, the proportion of viable cells was significantly decreased and the proportion of early apoptotic (Annexin-V-PE +/7AAD-) cells was significantly increased for all four homeopathic preparations. Based on the PI-staining cell cycle data, cells treated with <i>Hecla lava</i> and <i>Carboneum sulphuratum</i> showed a statistically significant accumulation in the sub-G0/G1 phase of the cell cycle (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong> This is the first study to demonstrate that each of four homeopathic medicines causes apoptosis in a MM cell line. Further exploration of the potential of <i>Arsenicum album</i>, <i>Hecla lava</i>, <i>Carcinosinum</i> and <i>Carboneum sulphuratum</i> as a complementary therapeutic option in MM is warranted.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":"44-49"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141456448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}