顺势疗法实践中的概率推理及其对临床研究的启示。

IF 1.2 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE
Homeopathy Pub Date : 2024-08-01 Epub Date: 2023-10-31 DOI:10.1055/s-0043-1775993
Fabrice Sébastien Berna, Jean-Lionel Bagot
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引用次数: 0

摘要

Hahnemann提出的相似原理在为患者选择正确的顺势疗法药物方面具有挑战性的实际后果。根据这一原则,只有最适合特定患者整体症状的药物才能真正治愈:这在很大程度上取决于顺势疗法的临床分析。此外,根据疾病的特点,患者的疾病可能或多或少是可以治愈的。在日常实践中,顺势疗法者通常应用贝叶斯推理来处理与医学和疾病相关的不确定性。我们认为,顺势疗法的临床研究将通过整合(1)给定药物对特定患者有效的概率和(2)患者疾病(或症状)可治愈的概率的这种先验估计来获得益处。因此,我们建议,未来的N选1设计试验可能会获得(1)通过为面临特定疾病的特定患者测试少量“最佳候选”药物(而不是一种),以及(2)通过仔细预先估计(a)每种选择的药物对该患者有效,以及(b)患者的疾病与该药物可逆的概率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Probabilistic Reasoning in Homeopathy Practice and its Implications for Clinical Research.

The principle of similitude put forward by Hahnemann has challenging practical consequences in the selection of the right homeopathic medicine for a patient. According to this principle, only the medicines that best fit the totality of the symptoms of a given patient are supposed to really cure: this greatly depends on the homeopath's clinical analysis. In addition, a patient's illness may be more or less curable, depending on the characteristics of the disease. In their daily practice, homeopaths typically apply Bayesian reasoning to deal with uncertainty associated with both medicine and disease. We suggest that clinical research on homeopathy would gain by integrating this kind of prior estimation of (1) the probability of a given medicine being effective for that particular patient and (2) the probability of the patient's disease (or symptoms) being curable. We therefore suggest that future trials of N-of-1 design may gain (1) by testing a small number of "best candidate" medicines (instead of one) for a given patient facing a given disease, and (2) by including careful prior estimations of the probabilities that (a) each selected medicine will be efficient for that patient and (b) the patient's disease will be reversible with the medicine.

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来源期刊
Homeopathy
Homeopathy 医学-全科医学与补充医学
CiteScore
3.40
自引率
70.60%
发文量
34
审稿时长
20.1 weeks
期刊介绍: Homeopathy is an international peer-reviewed journal aimed at improving the fundamental understanding and clinical practice of homeopathy by publishing relevant high-quality original research articles, reviews, and case reports. It also promotes commentary and debate on matters of topical interest in homeopathy.
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