Autism Research最新文献_第4页

Intact Visual Correlation Detection in Autistic Adults 自闭症成人完整视觉相关检测。

IF 3.9 2区医学

Autism Research Pub Date : 2026-09-23 Epub Date: 2026-08-03 DOI: 10.1002/aur.70339

Lukas Vogelsang, Marin Vogelsang, Cindy E. Li, Margaret Kjelgaard, Annie Cardinaux, Charles A. Nelson, Pawan Sinha

{"title":"Intact Visual Correlation Detection in Autistic Adults","authors":"Lukas Vogelsang, Marin Vogelsang, Cindy E. Li, Margaret Kjelgaard, Annie Cardinaux, Charles A. Nelson, Pawan Sinha","doi":"10.1002/aur.70339","DOIUrl":"10.1002/aur.70339","url":null,"abstract":"<p>The ability to detect recurring temporal co-occurrence, or temporal correlation, of sensory events is fundamental for organizing perceptual input into coherent representations. Although past work has revealed differences across several aspects of temporal processing in autism, it is unknown whether autistic and non-autistic individuals differ in the key computation of correlation detection. Here, we examined this question in the visual domain using an online task. A total of 143 age- and sex-matched adults (73 autistic, 70 non-autistic) viewed sequences in which three visual elements stochastically alternated between bright and dark states. Two of these were disks, and the third was a surrounding annulus. Participants indicated which of the two disks co-occurred more reliably with the annulus. Accuracy increased systematically with correlation strength in both groups, but there were no significant group differences and no negative association between performance and autistic trait scores when controlling for nonverbal IQ. These findings suggest that visual correlation detection, under the conditions tested here, is preserved in autistic adults. This points to a key aspect of temporal processing in autism that may provide a stable foundation for perceptual organization even amid challenges reported in other timing-related domains, such as higher-level temporal prediction. These results set the stage for future research to identify the mechanisms underlying both preserved and divergent temporal processes, and to translate these findings into evidence-based support that builds on the observed strengths of autistic individuals.</p>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 9","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/aur.70339","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Robots for Autism Therapy 自闭症治疗的机器人。

IF 3.9 2区医学

Autism Research Pub Date : 2026-09-23 Epub Date: 2026-08-04 DOI: 10.1002/aur.70338

Rebecca Ramnauth, Frederick Shic, Brian Scassellati

{"title":"Robots for Autism Therapy","authors":"Rebecca Ramnauth, Frederick Shic, Brian Scassellati","doi":"10.1002/aur.70338","DOIUrl":"10.1002/aur.70338","url":null,"abstract":"<div>\u0000 \u0000 <p>A growing body of work on robot-mediated therapy suggests that robots can elicit engagement and novel social behaviors among users with autism. In this narrative review, we trace the full historical arc of this field to date, from its inception in 2001 to 2024, covering 304 studies that present a robot for autism support. Early work largely consisted of short, highly structured sessions conducted in controlled laboratory or clinical environments. More recent research has shifted toward longer-term, real-world deployments in which robots operate with greater autonomy and engage users over multiple days or weeks. However, evidence for lasting and generalized benefits is still limited. The literature also remains focused primarily on children, with comparatively little research involving adults or individuals across a wider range of support needs. Despite rapid growth over these past two decades, the research remains fragmented across disciplinary boundaries, with robotics and clinical communities advancing similar goals without a cohesive, shared research framework. To address this, we offer a translational roadmap that details what interventions work, for whom, under which conditions, and why. We highlight current methodological gaps, outline key design considerations, and propose priorities for future research.</p>\u0000 </div>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 9","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148674590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atypical Attentional Effort During Visual Search in Autistic Adults: Evidence From Task-Evoked Pupillary Responses 自闭症成人视觉搜索过程中的非典型注意努力：来自任务诱发瞳孔反应的证据。

IF 3.9 2区医学

Autism Research Pub Date : 2026-09-23 Epub Date: 2026-07-29 DOI: 10.1002/aur.70332

Zainab Naaran, Amit Yashar

{"title":"Atypical Attentional Effort During Visual Search in Autistic Adults: Evidence From Task-Evoked Pupillary Responses","authors":"Zainab Naaran, Amit Yashar","doi":"10.1002/aur.70332","DOIUrl":"10.1002/aur.70332","url":null,"abstract":"<p>According to prevalent views, autistic individuals have a stronger tendency to allocate attention to details, as supported by reports of enhanced visual search performance. However, both the dynamics and the types of information involved in attentional guidance in autism are not fully understood. We addressed this issue by testing the influence of search history on visual search performance and pupil size in a long search display (Experiment 1) and on accuracy in a brief and masked—more attentionally demanding—search display (Experiment 2). Autistic (<i>N</i> = 48) and non-autistic (<i>N</i> = 45) participants searched for a color singleton target (all equiluminant colors) and responded by identifying its shape. In each trial, the target and distractor colors could be repeated, switched, or novel with respect to the previous trial. In Experiment 1, while overall reaction time was comparable across groups, the task-evoked pupillary responses (TEPRs) were smaller in the autistic group, indicating reduced attentional effort in autism. In Experiment 2, in a more attentionally demanding display, autistic individuals showed superior search accuracy. In both experiments, both groups showed a reliable effect of recent search history on performance, indicating that, similar to non-autistic individuals, autistic individuals rely on recent experience during attentional allocation. Alterations in attentional allocation and its interaction with recent experience in autism were reflected in pupil responses. These alterations may provide a sensitive marker of differences in the dynamics of attentional allocation in autism, which are reflected in behavioral measurements when display conditions are more attentionally demanding.</p>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 9","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/aur.70332","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transcriptomic Profiling of the Amygdala of Children With Autism Spectrum Disorder 自闭症谱系障碍儿童杏仁核转录组学分析。

IF 3.9 2区医学

Autism Research Pub Date : 2026-09-23 Epub Date: 2026-07-26 DOI: 10.1002/aur.70333

Jobin Babu, Ayushi Lal, Lavanya Challagundla, Obie Allen IV, Madeline Griffin, Barbara Gisabella, Harry Pantazopoulos

{"title":"Transcriptomic Profiling of the Amygdala of Children With Autism Spectrum Disorder","authors":"Jobin Babu, Ayushi Lal, Lavanya Challagundla, Obie Allen IV, Madeline Griffin, Barbara Gisabella, Harry Pantazopoulos","doi":"10.1002/aur.70333","DOIUrl":"10.1002/aur.70333","url":null,"abstract":"<div>\u0000 \u0000 <p>A growing number of studies point to a key role of the amygdala in Autism Spectrum Disorders (ASD). The amygdala is involved in several processes in ASD including emotional valence, facial recognition, regulation of social learning, empathy, and anxiety. Brain imaging and postmortem studies demonstrate altered amygdala development in children with ASD, associated with impairment in social behavior and anxiety. There is limited information regarding the molecular pathology of the amygdala in children with ASD. We conducted RNAseq profiling on postmortem amygdala samples from male children (4–14 years old) with ASD (<i>n</i> = 8) and normotypic male children (<i>n</i> = 6). Furthermore, we conducted drug repurposing analysis to identify compounds predicted to reverse the transcriptomic signatures identified in order to identify potential therapeutic targets for development of early intervention treatments. Full transcriptome gene expression profiling implicated molecular pathways involved in neuroimmune signaling, glycogen and carbohydrate metabolism, matrix metalloproteases, neurodevelopment, estrogen receptor signaling, and synaptic signaling. Targeted pathway analysis of the top 10% of genes ranked by log<sub>2</sub> fold change implicated pathways involved in extracellular matrix organization (ECM), immune signaling, and synaptic signaling. Our drug repurposing analysis identified sleep modifying compounds and anti-inflammatory compounds including COX2 and GSK3 inhibitors amongst the top predicted therapeutic compounds. PDGF receptor tyrosine kinase inhibitors were identified as a top potential therapeutic mechanism of action. Collectively, we identified alterations in immune signaling, ECM, and synaptic signaling in the amygdala of children with ASD. Furthermore, our findings highlight a number of potential therapeutic drug targets for development of early intervention strategies.</p>\u0000 </div>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 9","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148594784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Socioeconomic Status and Quantity of Shared Book Reading, But Not Screen Time, are Positively Associated With Language Skills in a Nationally Representative Sample of Autistic Children 在一项具有全国代表性的自闭症儿童样本中，社会经济地位和共同阅读书籍的数量，而不是屏幕时间，与语言技能呈正相关。

IF 3.9 2区医学

Autism Research Pub Date : 2026-09-23 Epub Date: 2026-07-27 DOI: 10.1002/aur.70321

M. Pecukonis, A. Geffin

{"title":"Socioeconomic Status and Quantity of Shared Book Reading, But Not Screen Time, are Positively Associated With Language Skills in a Nationally Representative Sample of Autistic Children","authors":"M. Pecukonis, A. Geffin","doi":"10.1002/aur.70321","DOIUrl":"10.1002/aur.70321","url":null,"abstract":"<div>\u0000 \u0000 <p>Studies have shown that both distal and proximal environmental factors influence language development in neurotypical children. More specifically, higher socioeconomic status (SES) and more frequent shared book reading have been linked to higher language skills in neurotypical children, while higher screen time has been linked to lower language skills. However, little research has focused on understanding how the environment shapes language development in autistic children, who often experience challenges using and/or understanding spoken language. The present study used data from the 2018–2022 United States National Survey of Children's Health to investigate the associations between SES, quantity of shared book reading and screen time experienced at home, and expressive and receptive language skills in a nationally representative sample of two to five year old autistic children. Structural equation modeling revealed that autistic children from higher SES households, and who experienced shared book reading more frequently at home, had higher expressive and receptive language skills. Shared book reading also mediated the association between SES and children's language skills. Contrary to what has been found in previous studies of neurotypical children, screen time was not associated with autistic children's expressive or receptive language skills. In all, findings suggest that distal (SES) and proximal (shared book reading) environmental factors play an important role in autistic children's language development. Findings have important implications for clinical practice, as interventions that promote frequent shared book reading may support autistic children's language development.</p>\u0000 </div>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 9","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148610863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Structure and Individual Patterns of Emotional and Behavioral Problems in Preschool Children With Autism Spectrum Disorder: Evidence From Network and Cluster Analyses 学龄前自闭症谱系障碍儿童情绪和行为问题的结构和个体模式：来自网络和聚类分析的证据。

IF 3.9 2区医学

Autism Research Pub Date : 2026-09-23 Epub Date: 2026-08-11 DOI: 10.1002/aur.70343

Lijing Lin, Bingqian Gao, Yanting Hou, Wenwen Huang, Xiaosong Li, Ling Wang, Yidong Shen, Jianjun Ou

{"title":"The Structure and Individual Patterns of Emotional and Behavioral Problems in Preschool Children With Autism Spectrum Disorder: Evidence From Network and Cluster Analyses","authors":"Lijing Lin, Bingqian Gao, Yanting Hou, Wenwen Huang, Xiaosong Li, Ling Wang, Yidong Shen, Jianjun Ou","doi":"10.1002/aur.70343","DOIUrl":"10.1002/aur.70343","url":null,"abstract":"<div>\u0000 \u0000 <p>This study explored the interactions between emotional and behavioral symptoms in preschool children with autism spectrum disorder (ASD) and identified potential clinical subtypes based on these interrelationships. A total of 1886 preschool children with ASD and 285 age-matched typically developing (TD) children were assessed using the Child Behavior Checklist for ages 1.5–5. Symptom networks were estimated using the EBICglasso algorithm, and group differences were evaluated via network comparison tests. Subgroups within the ASD sample were identified using Individual Difference Symptom Networks (IDSN) with k-means clustering. The results revealed distinct network structures between the ASD and TD groups, with emotional reactivity demonstrating the highest centrality in the ASD network. Two distinct ASD subgroups (ASD-A and ASD-B) were identified, which showed significant differences from the TD group across all emotional and behavioral dimensionsin the CBCL 1.5–5. The subgroups differed significantly in overall network strength and specific edge connections, particularly between aggressive behavior and withdrawal problems. The findings indicate that emotional reactivity may play a central role in the symptom network of preschool children with ASD. The identification of two clinical subgroups with distinct symptom connectivity patterns provides valuable insights for developing more individualized and targeted intervention strategies. ASD-A subgroup points to the potential value of comprehensive early intervention programs, whereas ASD-B subgroup highlights the need for functional communication training and social engagement strategies.</p>\u0000 </div>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 9","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148714814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Night-to-Night Changes in REM Sleep Are Associated With Symptom Severity in Children With Autism Spectrum Disorder: A Two-Night Home Polysomnography Study 自闭症谱系障碍儿童快速眼动睡眠的夜间变化与症状严重程度有关：一项两夜家庭多导睡眠图研究

IF 3.9 2区医学

Autism Research Pub Date : 2026-09-23 Epub Date: 2026-07-26 DOI: 10.1002/aur.70322

Jian Jiao, Hang Zhang, Xia Yang, Lu Tan, Taomei Li, Xiangdong Tang

{"title":"Night-to-Night Changes in REM Sleep Are Associated With Symptom Severity in Children With Autism Spectrum Disorder: A Two-Night Home Polysomnography Study","authors":"Jian Jiao, Hang Zhang, Xia Yang, Lu Tan, Taomei Li, Xiangdong Tang","doi":"10.1002/aur.70322","DOIUrl":"10.1002/aur.70322","url":null,"abstract":"<div>\u0000 \u0000 <p>Sleep disturbances are highly prevalent in autism spectrum disorder (ASD), yet conventional single-night polysomnography (PSG) provides limited insight into dynamic sleep regulatory processes. Using the Synaptic Homeostasis Hypothesis as a conceptual framework, we quantified night-to-night changes (Δ; Night 2 − Night 1) in sleep architecture across two consecutive nights of home-based PSG and examined their association with ASD symptom severity. Seventy-nine children with ASD, stratified into mild ASD (M-ASD, <i>n</i> = 35) and moderate-to-severe ASD (MS-ASD, <i>n</i> = 44) subgroups using the Childhood Autism Rating Scale, and 30 typically developing controls (TDC) participated. Overall sleep-continuity changes were broadly comparable between ASD and TDC groups. However, sleep-architecture Δ measures showed a severity-related pattern: the M-ASD subgroup exhibited an overnight increase in rapid eye movement sleep percentage (ΔREM% = +2.6%, <i>p</i> = 0.002), whereas the MS-ASD subgroup showed no significant change (ΔREM% = −0.1%, <i>p</i> = 0.922). An adjusted pairwise comparison indicated a greater ΔREM% increase in M-ASD than in MS-ASD (adjusted mean difference = 3.4%, 95% CI: 1.2 to 5.6; Bonferroni-corrected <i>p</i> = 0.009). A similar exploratory difference was observed for NREM1%. ΔREM% was modestly and negatively associated with ASD symptom severity in correlation analysis (<i>ρ</i> = −0.234, <i>p</i> = 0.038) and age- and gender-adjusted regression analysis (<i>β</i> = −0.286, <i>p</i> = 0.016). Sensitivity analyses showed broadly consistent patterns, although severity-stratified overall effects were attenuated after FDR correction. These findings support further investigation of PSG-derived dynamic sleep measures as hypothesis-generating correlates of clinical heterogeneity in ASD.</p>\u0000 </div>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 9","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148594727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

‘They Even Have the Capacity, but the Places Aren't Prepared to Receive Them’: Community Environment and Participation of Autistic Children in a Family-Engaged Research Analysis “他们甚至有能力，但地方没有准备好接受他们”：社区环境和自闭症儿童参与家庭参与的研究分析。

IF 3.9 2区医学

Autism Research Pub Date : 2026-09-23 Epub Date: 2026-07-19 DOI: 10.1002/aur.70316

Léia Cordeiro de Oliveira, Cid André Fidelis de Paula Gomes, Gustavo Pietracatelli Janizello, Wallace Pereira Silva, Alice Soper, Monika Novak-Pavlic, Olaf Kraus de Camargo, Soraia Micaela Silva

{"title":"‘They Even Have the Capacity, but the Places Aren't Prepared to Receive Them’: Community Environment and Participation of Autistic Children in a Family-Engaged Research Analysis","authors":"Léia Cordeiro de Oliveira, Cid André Fidelis de Paula Gomes, Gustavo Pietracatelli Janizello, Wallace Pereira Silva, Alice Soper, Monika Novak-Pavlic, Olaf Kraus de Camargo, Soraia Micaela Silva","doi":"10.1002/aur.70316","DOIUrl":"10.1002/aur.70316","url":null,"abstract":"<p>To examine the associations between community environmental barriers and support and the participation of autistic children, and to interpret these findings from the perspective of caregivers engaged as research partners. This cross-sectional observational study employed a mixed-methods design. The first phase comprised analytical and exploratory quantitative analyses. Caregivers of autistic children aged 5–12 years reported participation outcomes—frequency, involvement, and desire for change—using the Brazilian version of the Participation and Environment Measure for Children and Youth (PEM-CY) and CARS-BR with 80 caregivers of children aged 5–12. Phase 1 involved path analysis to test associations between community environment, income, autism severity, and participation (frequency, involvement, desire for change). Phase 2 employed a constructivist-interpretivist approach, where five caregivers acted as research partners to interpret quantitative results via reflexive thematic analysis. Quantitative analysis showed no statistically significant associations between environmental factors and participation outcomes, despite frequent reports of barriers. In Phase 2, research partners identified social inclusion, safety, and logistical constraints as critical. They highlighted that low participation often stems from unwelcoming contexts and limited informal peer interaction, rather than a lack of desire to engage. Integrating findings from both phases, the study suggests that the low participation of autistic children in community settings may reflect, at least in part, protective choices adopted in response to contexts perceived as unwelcoming, unsafe, and insufficiently supportive, rather than a lack of desire for participation.</p>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 9","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/aur.70316","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148521283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Personalized Lifespan Approach to Autism Assessment: A Clinical and System Framework for Developmentally Informed Assessment Across the Life-Course 自闭症评估的个性化生命周期方法：在整个生命过程中发展信息评估的临床和系统框架。

IF 3.9 2区医学

Autism Research Pub Date : 2026-08-13 Epub Date: 2026-06-19 DOI: 10.1002/aur.70294

Melanie Penner, Rebecca McNally Keehn

{"title":"Personalized Lifespan Approach to Autism Assessment: A Clinical and System Framework for Developmentally Informed Assessment Across the Life-Course","authors":"Melanie Penner, Rebecca McNally Keehn","doi":"10.1002/aur.70294","DOIUrl":"10.1002/aur.70294","url":null,"abstract":"<p>The increasing prevalence of autism has led to considerable system challenges as specialist-driven approaches have struggled to keep pace. Recent research has challenged status quo models by demonstrating that community-based pediatric clinicians can accurately diagnose autism in young children. This research provides an opportunity to further expand capacity of community systems to conduct developmentally relevant, context-specific assessments of autistic people over their lifespan. In this Commentary, we propose a <i>personalized lifespan approach to autism assessment</i> as a precision care and system organization framework that considers the ongoing and evolving needs of autistic people and aligns the necessary expertise and resources to provide focused assessment when it is most informative. This framework consists of three key principles: (1) assessment is not a one-time, one-size-fits-all event; instead, assessment continues across the lifespan; (2) assessments should generate information that is relevant to the individual's current needs and life stage; and (3) wherever possible, community-based expertise should be engaged to promote the right assessment at the right time in the right place. Adopting this framework can reduce system access challenges, while also addressing the ongoing assessment needs of an autistic person across their life course.</p>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 8","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/aur.70294","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148284911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Valence-Arousal Asymmetry: Rethinking Facial Emotion Recognition in Preschool Autism Through Eye-Tracking 效价觉醒不对称：通过眼动追踪重新思考学龄前自闭症的面部情绪识别。

IF 3.9 2区医学

Autism Research Pub Date : 2026-08-13 Epub Date: 2026-06-19 DOI: 10.1002/aur.70295

FanShuai Bu, RuoXi Teng, Mingyu Zhang, Hang Zhou, Jing Lyu, Lu Jiao, Chen Cai, Qian Jin

{"title":"Valence-Arousal Asymmetry: Rethinking Facial Emotion Recognition in Preschool Autism Through Eye-Tracking","authors":"FanShuai Bu, RuoXi Teng, Mingyu Zhang, Hang Zhou, Jing Lyu, Lu Jiao, Chen Cai, Qian Jin","doi":"10.1002/aur.70295","DOIUrl":"10.1002/aur.70295","url":null,"abstract":"<div>\u0000 \u0000 <p>Facial emotion recognition is a fundamental socioemotional skill often impaired in autism spectrum disorder (ASD). Yet findings remain inconsistent, partly due to reliance on discrete emotion categories that neglect affective dimensions. Guided by a valence–arousal framework, this study re-examined facial emotion recognition in preschool children with ASD using eye-tracking and pupilometry. Eighty-two Chinese preschoolers (40 ASD, 42 typically developing [TD]) completed an emotion recognition task with facial stimuli systematically varied in valence (positive vs. negative) and arousal (high vs. low). Eye movements and pupil size were analyzed within a 2 (group) × 2 (valence) × 2 (arousal) × 4 (AOI: eyes, nose, mouth, other) design. Results showed robust effects of valence: TD children allocated more fixations and longer gaze to positive faces, especially the eye region, whereas ASD children showed attenuated patterns. Arousal effects were weaker but interacted with valence, with high-arousal negative faces eliciting avoidance and high-arousal positive faces enhancing pupil responses. These findings highlight valence–arousal asymmetry as a key mechanism underlying atypical emotion processing in preschool ASD and underscore the value of dimensional approaches for early socioemotional assessment and intervention.</p>\u0000 </div>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 8","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148284941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0