Autism Research最新文献_第10页

Parental experiences and perspectives of healthcare providers' genetic testing recommendations for their children diagnosed with autism spectrum disorder in the United States 美国自闭症谱系障碍家长对医疗服务提供者为其被诊断患有自闭症谱系障碍的子女提供基因检测建议的经验和看法。

IF 5.3 2区医学

Autism Research Pub Date : 2024-11-13 DOI: 10.1002/aur.3262

Shixi Zhao, Ming Li, Wei-Ju Chen, Brandon J. Rennie, Yu–Yu Hsiao, Yue Guan

{"title":"Parental experiences and perspectives of healthcare providers' genetic testing recommendations for their children diagnosed with autism spectrum disorder in the United States","authors":"Shixi Zhao, Ming Li, Wei-Ju Chen, Brandon J. Rennie, Yu–Yu Hsiao, Yue Guan","doi":"10.1002/aur.3262","DOIUrl":"10.1002/aur.3262","url":null,"abstract":"Although genetic testing is recommended for all children diagnosed with autism spectrum disorder (ASD) in the United States, it remains unclear how many parents have received and followed these recommendations. This study aimed to assess parental experiences and perspectives of healthcare providers' genetic testing recommendations. A total of 1043 parents of children with ASD from Simons Foundation Powering Autism Research for Knowledge completed an online survey. Only about one-third of the parents (34.2%) reported that their children's providers had recommended genetic testing. Factors associated with whether parents received these recommendations included the type of healthcare providers diagnosing ASD, parents' knowledge of genetic testing, the age of their children's diagnosis, and the presence of certain co-occurring medical conditions in their children. Our study also revealed that most parents (76.9%) who received recommendations had pursued genetic testing for their children. Adherence to the recommendations was associated with the characteristics of the parents (i.e., age and employment status) and children (i.e., gender), and their trust in the information from providers. The findings highlight the critical role of healthcare providers in facilitating genetic testing among families of children with ASD. Healthcare providers are recommended to increase their competencies and practice in providing genetic testing recommendations for ASD, assist parents in navigating testing challenges, and support parents through the testing process.","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"17 12","pages":"2471-2486"},"PeriodicalIF":5.3,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inner experiences, mental health, and well-being in autistic and non-autistic adults 自闭症和非自闭症成人的内心体验、心理健康和幸福感。

IF 5.3 2区医学

Autism Research Pub Date : 2024-11-13 DOI: 10.1002/aur.3273

Micah O. Mazurek, Jessica Pappagianopoulos, Sophie Brunt, Rose Nevill, Michelle Menezes, Christina Burroughs, Eleonora Sadikova, Jessica V. Smith, Mya Howard

{"title":"Inner experiences, mental health, and well-being in autistic and non-autistic adults","authors":"Micah O. Mazurek, Jessica Pappagianopoulos, Sophie Brunt, Rose Nevill, Michelle Menezes, Christina Burroughs, Eleonora Sadikova, Jessica V. Smith, Mya Howard","doi":"10.1002/aur.3273","DOIUrl":"10.1002/aur.3273","url":null,"abstract":"The nature of autistic adults' everyday inner experiences has been largely unstudied. The purpose of this study was to examine patterns of inner experiences and how they relate to mental health and wellness among autistic and non-autistic adults. Autistic (n = 303) and non-autistic (n = 289) adults (ages 21–82) completed online surveys assessing their anxiety, depression, happiness, life satisfaction, and inner thinking patterns, (inner speaking [i.e., verbal thinking], inner seeing [i.e., visual thinking], unsymbolized thinking, feelings, sensory awareness, self-talk). Group differences in inner thinking were examined using Mann–Whitney U and chi-square tests. Correlations and multiple linear regressions examined associations between inner experiences, mental health, and well-being. Autistic adults had greater use of inner speaking and sensory awareness, compared to non-autistic adults. The most common primary mode of inner experience for both groups was inner speaking, while fewer autistic adults reported that experiencing thoughts as feelings was their primary modality. Autistic adults reported greater use of self-talk for social assessment, self-criticism, and self-management purposes, compared to non-autistic adults. Experiencing thoughts as inner speech and as feelings were associated with anxiety in both groups. Using self-talk for social assessment and self-criticism purposes was correlated with anxiety and depression in both groups, while using self-talk for self-management was associated with depression and anxiety only among autistic adults. The results suggest that autistic and non-autistic adults have similarities in overall patterns of inner thinking, yet autistic adults may be more likely to engage in self-talk as a strategy to manage challenging day-to-day experiences.","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"17 12","pages":"2676-2688"},"PeriodicalIF":5.3,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11638894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

GABA and glutamate measurements in temporal cortex of autistic children 自闭症儿童颞叶皮层的 GABA 和谷氨酸测量。

IF 5.3 2区医学

Autism Research Pub Date : 2024-11-11 DOI: 10.1002/aur.3253

Muhammad G. Saleh, Luke Bloy, Lisa Blaskey, Timothy P. L. Roberts

{"title":"GABA and glutamate measurements in temporal cortex of autistic children","authors":"Muhammad G. Saleh, Luke Bloy, Lisa Blaskey, Timothy P. L. Roberts","doi":"10.1002/aur.3253","DOIUrl":"10.1002/aur.3253","url":null,"abstract":"Autism spectrum disorder (ASD) is a neurodevelopmental disorder and presents with challenges in social communication. A hypothesized underlying contributing mechanism is the imbalance in excitation and inhibition (E/I), partly influenced by the levels of excitatory neurotransmitter glutamate (Glu) and inhibitory neurotransmitter γ-aminobutyric acid (GABA) in the brain. Although many have reported the levels of GABA and Glu in the brain, only a few reports address the temporal cortex and then only with a small sample of autistic children, and often only in one hemisphere. We used a macromolecular suppressed edited-magnetic resonance spectroscopy (MRS) sequence to study GABA and Glu (as potential key players influencing E/I) in a large sample of children with ASD in the right and left temporal cortices of children with (N = 56) and without (N = 30) ASD (7–18 years). As a group, children with ASD exhibited no differences in the left hemisphere (GABA and Glu Cohen's |d|: 0.24 and 0.03), but the right hemisphere showed higher GABA and lower Glu concentrations (GABA and Glu Cohen's |d|: 0.53 and 0.65) compared to neurotypicals. Furthermore, a negative association was found between the right hemisphere Glu levels of the ASD group and a clinical assessment tool (r = −0.361, p = 0.022), reflecting autism trait severity (social responsiveness scale). In conclusion, we highlight the chemical abnormalities in children with ASD through a cross-sectional measurement. Longitudinal studies are warranted to determine whether these chemical levels persist or resolve over development.","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"17 12","pages":"2558-2571"},"PeriodicalIF":5.3,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11638920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emotion dysregulation in autism: Severity and correlates in early childhood 自闭症的情绪失调：幼儿期的严重程度和相关因素。

IF 5.3 2区医学

Autism Research Pub Date : 2024-11-08 DOI: 10.1002/aur.3264

Jessie B. Northrup, Amy G. Hartman, Kristen T. MacKenzie, Shalini Sivathasan, Safaa Eldeeb, Carla A. Mazefsky

{"title":"Emotion dysregulation in autism: Severity and correlates in early childhood","authors":"Jessie B. Northrup, Amy G. Hartman, Kristen T. MacKenzie, Shalini Sivathasan, Safaa Eldeeb, Carla A. Mazefsky","doi":"10.1002/aur.3264","DOIUrl":"10.1002/aur.3264","url":null,"abstract":"Emotion dysregulation (ED) is common and severe in older autistic youth, but is rarely the focus of early autism screening or intervention. Moreover, research characterizing ED in the preschool years (when autism is typically diagnosed) is limited. This study aimed to characterize ED in autistic children by examining (1) prevalence and severity of ED as compared to children without an autism diagnosis; and (2) correlates of ED in autistic children. A sample of 1864 parents (Mean child age = 4.21 years, SD = 1.16 years; 37% female) of 2–5 year-old children with (1) autism; (2) developmental concerns, but no autism; and (3) no developmental concerns or autism completed measures via an online questionnaire. ED was measured using the Emotion Dysregulation Inventory-Young Child, a parent report measure characterizing ED across two dimensions: Reactivity (fast, intense emotional reactions) and dysphoria (low positive affect, sadness, unease). Autistic preschoolers, compared to peers without developmental concerns, had more severe ED (+1.12 SD for reactivity; +0.60 SD for dysphoria) and were nearly four and three times more likely to have clinically significant reactivity and dysphoria, respectively. Autistic traits, sleep problems, speaking ability, and parent depression were the strongest correlates of ED in the autism sample. While more work is needed to establish the prevalence, severity, and correlates of ED in young autistic children, this study represents an important first step. Results highlight a critical need for more high-quality research in this area as well as the potential value of screening and intervention for ED in young autistic children.","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"17 12","pages":"2662-2675"},"PeriodicalIF":5.3,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multilingualism impacts children's executive function and core autism symptoms 使用多种语言会影响儿童的执行功能和自闭症的核心症状。

IF 5.3 2区医学

Autism Research Pub Date : 2024-11-07 DOI: 10.1002/aur.3260

Celia Romero, Zachary T. Goodman, Lauren Kupis, Bryce Dirks, Meaghan V. Parlade, Amy L. Beaumont, Sandra M. Cardona, Jason S. Nomi, Michael Alessandri, Lynn K. Perry, Lucina Q. Uddin

{"title":"Multilingualism impacts children's executive function and core autism symptoms","authors":"Celia Romero, Zachary T. Goodman, Lauren Kupis, Bryce Dirks, Meaghan V. Parlade, Amy L. Beaumont, Sandra M. Cardona, Jason S. Nomi, Michael Alessandri, Lynn K. Perry, Lucina Q. Uddin","doi":"10.1002/aur.3260","DOIUrl":"10.1002/aur.3260","url":null,"abstract":"Autism spectrum disorder (ASD) is associated with marked heterogeneity in executive function (EF) abilities. EF components including inhibition and shifting are related to ASD core symptoms such as perspective taking, social communication, and repetitive behavior. Recent research suggests that multilingualism may have a beneficial impact on EF abilities, especially in children with ASD. However, there remains a lack of comprehensive understanding regarding the relationships between multilingualism, EF, and core symptoms in children with ASD. Here, we examined these associations in 7–12-year-old children with and without ASD (N = 116; 53 ASD, Mean age = 9.94 years). Results suggest that multilingual children have stronger parent-reported inhibition, shifting, and perspective-taking skills than monolingual children. Furthermore, we found a significant interaction between diagnosis and multilingual status on inhibition, such that the effects of multilingualism were stronger for children with ASD than typically developing (TD) children. Finally, we found indirect effects of multilingualism on perspective taking, social communication, and repetitive behaviors mediated by EF skills. These results demonstrate the supportive influences multilingual experience might have on bolstering EF and reducing ASD-related symptoms.","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"17 12","pages":"2645-2661"},"PeriodicalIF":5.3,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11638936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142592391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Music therapy improves engagement and initiation for autistic children with mild intellectual disabilities: A randomized controlled study 音乐疗法提高了轻度智障自闭症儿童的参与度和主动性：随机对照研究。

IF 5.3 2区医学

Autism Research Pub Date : 2024-11-07 DOI: 10.1002/aur.3254

Yen Na Yum, Kean Poon, Way Kwok-Wai Lau, Fuk Chuen Ho, Kuen Fung Sin, King Man Chung, Ho Yan Lee, Di Chao Liang

{"title":"Music therapy improves engagement and initiation for autistic children with mild intellectual disabilities: A randomized controlled study","authors":"Yen Na Yum, Kean Poon, Way Kwok-Wai Lau, Fuk Chuen Ho, Kuen Fung Sin, King Man Chung, Ho Yan Lee, Di Chao Liang","doi":"10.1002/aur.3254","DOIUrl":"10.1002/aur.3254","url":null,"abstract":"This study aimed to evaluate the effectiveness of music therapy (MT) for children with co-occurring autism spectrum disorder (ASD) and intellectual disabilities (ID) and explore whether pre-intervention quantitative electroencephalogram (qEEG) responses can predict outcomes. A randomized controlled trial was conducted with 33 children receiving MT and 34 receiving an active control therapy. Participants received either MT or a non-musical social skills intervention for 45 min weekly over 12 weeks. Primary outcomes were measured using the Childhood Autism Rating Scale (CARS-2), along with the parent-rated Social Responsiveness Scale (SRS-2) and video coding of social behaviors. Both conditions significantly improved in CARS-2 scores at 2 weeks and 4 months post-intervention, with no differences between MT and control conditions. No changes were found in SRS-2 scores. While both conditions showed reduced disengagement after intervention, only the MT condition showed increased engagement and initiation. Strong qEEG responses to social scenes and music predicted increased initiation, indicating its potential to help tailor interventions. These results support incorporating MT into standard services and further research on qEEG predictors.","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"17 12","pages":"2702-2722"},"PeriodicalIF":5.3,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142592394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A systematic review and meta-analysis of atypical visual attention towards non-social stimuli in preschoolers with autism spectrum disorder 自闭症谱系障碍学龄前儿童对非社交刺激的非典型视觉注意力的系统回顾和荟萃分析。

IF 5.3 2区医学

Autism Research Pub Date : 2024-11-06 DOI: 10.1002/aur.3261

Julian R. Hinz, Fillip F. Eikeseth, Katarzyna Chawarska, Svein Eikeseth

{"title":"A systematic review and meta-analysis of atypical visual attention towards non-social stimuli in preschoolers with autism spectrum disorder","authors":"Julian R. Hinz, Fillip F. Eikeseth, Katarzyna Chawarska, Svein Eikeseth","doi":"10.1002/aur.3261","DOIUrl":"10.1002/aur.3261","url":null,"abstract":"Research on attention towards non-social stimuli in preschoolers with autism spectrum disorder (ASD) has increased over the past decade; however, findings have been inconsistent. It has been suggested that stimuli relating to common circumscribed interests (CIs) elicit more attention than non-CI related stimuli. This meta-analysis synthesizes results from 31 studies that compared attention towards non-social stimuli in children with ASD under the age of five with typically developing (TD) controls using eye-tracking. Additional subgroup analysis comparing studies that employed non-social stimuli related to CIs frequently reported in adults with ASD to studies using non-CI related stimuli were conducted. Meta-regressions with age, sex, stimulus dimension, nonverbal DQ, and symptom severity were conducted. Results show small (g = 0.39) but significantly higher attention towards non-social stimuli for the ASD group. However, when studies were split based on stimulus type no significant differences for non-CI related stimuli was found. Meanwhile studies employing CI related stimuli reported significant large effects on attention allocation (g = 0.69). None of the conducted regressions reached significance. The findings show increased non-social attention in children with ASD is driven by CI related content rather than a general non-social attentional bias. The findings and future research directions are discussed.","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"17 12","pages":"2628-2644"},"PeriodicalIF":5.3,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11638896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What role does the environment play in language development? Exploring the associations among socioeconomic status, parent language input, and language skills in school-aged children with autism 环境在语言发展中扮演什么角色？探索自闭症学龄儿童的社会经济地位、父母语言输入和语言技能之间的关联。

IF 5.3 2区医学

Autism Research Pub Date : 2024-11-04 DOI: 10.1002/aur.3252

Meredith Pecukonis, Lindsay K. Butler, Helen Tager-Flusberg

{"title":"What role does the environment play in language development? Exploring the associations among socioeconomic status, parent language input, and language skills in school-aged children with autism","authors":"Meredith Pecukonis, Lindsay K. Butler, Helen Tager-Flusberg","doi":"10.1002/aur.3252","DOIUrl":"10.1002/aur.3252","url":null,"abstract":"Language development in children with autism is influenced by proximal (e.g., parent language input) and distal (e.g., socioeconomic status) environmental constructs. Studies have found that “rich and responsive” parent language input supports autistic children's language development, and recent work has reported positive associations between measures of socioeconomic status (SES) and child language skills. However, little is known about how these proximal and distal environmental constructs interact to shape language development in autism. In a sample of 74 autistic school-aged children, the present study investigated the associations among measures of SES, the quantity and quality of language produced by parents and children during home-based dyadic parent–child interactions, and children's expressive and receptive language skills. Results showed that annual household income was positively associated with parent number of total words (NTW), parent number of different words (NDW), and parent mean length of utterance (MLU), while neither parent education level nor annual household income were significantly associated with measures of child language skills. Parent MLU was positively associated with child MLU and child expressive language skills. Findings suggest that annual household income may influence both the quantity and quality of parent language input, and that parent MLU, a qualitative measure of parent language input, may play a particularly important role in shaping autistic children's expressive language development. Future research should study longitudinal associations among SES, parent language input, and child language skills, as identifying environmental predictors of language skills in autism may facilitate the creation of more effective interventions that support language development.","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"17 12","pages":"2614-2627"},"PeriodicalIF":5.3,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parental age at birth, telomere length, and autism spectrum disorders in the UK Biobank cohort 英国生物库队列中父母的出生年龄、端粒长度和自闭症谱系障碍。

IF 5.3 2区医学

Autism Research Pub Date : 2024-10-30 DOI: 10.1002/aur.3258

Qiaofeng Ye, Abner T. Apsley, Waylon J. Hastings, Laura Etzel, Craig Newschaffer, Idan Shalev

{"title":"Parental age at birth, telomere length, and autism spectrum disorders in the UK Biobank cohort","authors":"Qiaofeng Ye, Abner T. Apsley, Waylon J. Hastings, Laura Etzel, Craig Newschaffer, Idan Shalev","doi":"10.1002/aur.3258","DOIUrl":"10.1002/aur.3258","url":null,"abstract":"Older parental age at birth is associated with increased risk of autism spectrum disorders (ASD) in offspring. Independently, shorter telomere length (TL) has also been shown to be associated with ASD in children. However, older paternal age at birth, with or without controlling for maternal age, has been associated with longer TL, a seemingly contradictory finding. Here, we conducted a retrospective cohort study among participants in the UK Biobank to disentangle associations between leukocyte TL and ASD status in adults, and the potential moderation by parental age on adult offspring's TL. Participants with ASD diagnosis (N = 87) with a mean age of 46.0 (SD 4.4) years were matched to participants without ASD diagnosis (N = 870) based on age, sex, ethnicity, education, household income, and assessment center. No statistically significant differences were seen in TL between participants with and without ASD when parental age at birth was not considered. However, there was a significant interaction between ASD diagnostic status and parental age on participants' TL, such that older paternal or maternal age at birth was more strongly associated with longer TL in participants with ASD. This study suggests that the shortened TL observed in children with ASD in previous research may partially depend on parental age at birth. Future studies tracking TL attrition before ASD diagnosis are warranted to depict temporal associations and the interacting effects of parental age at birth and ASD status on TL across the lifespan.","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"17 11","pages":"2223-2231"},"PeriodicalIF":5.3,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/aur.3258","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Concurrent predictors of behavioral inflexibility in minimally verbal and verbal autistic children 自闭症儿童中最小言语障碍和言语障碍行为不灵活的并发预测因素。

IF 5.3 2区医学

Autism Research Pub Date : 2024-10-30 DOI: 10.1002/aur.3251

Charlotte Gaynor, Yanru Chen, Helen Tager-Flusberg

{"title":"Concurrent predictors of behavioral inflexibility in minimally verbal and verbal autistic children","authors":"Charlotte Gaynor, Yanru Chen, Helen Tager-Flusberg","doi":"10.1002/aur.3251","DOIUrl":"10.1002/aur.3251","url":null,"abstract":"Behavioral inflexibility (BI) refers to the rigid and inflexible patterns of behaviors that are a core aspect of autism. Few studies have investigated BI in autism separately from other restricted and repetitive behaviors (RRBs). The present study used a relatively new measure, the behavioral inflexibility scale (BIS; Lecavalier, L., Bodfish, J., Harrop, C., Whitten, A., Jones, D., Pritchett, J., Faldowski, R., & Boyd, B. (2020). Autism Research, 13(3), 489–499), to examine the relationship of BI and variables that are both core symptoms in autism as well as symptoms associated with cooccurring mental health conditions, atypical sensory experiences, and adaptive functioning in a sample of 87 children with autism. Additionally, we aimed to understand how these relationships may be related to autistic individuals' verbal status: minimally verbal (MV) or verbal. Results revealed that anxiety, attention deficit/hyperactive, depressive, oppositional defiance problems, and sensory differences were all significantly correlated with BI in the MV group. In contrast, only anxiety, depressive, and oppositional defiance problems were significantly correlated with BI in the verbal group. Linear regression analyses showed that oppositional defiance problems and atypical sensory experiences explained a significant proportion of the variance of BI in the MV group, whereas only depressive problems were significant in the verbal group after accounting for other mental health conditions. Overall, our findings demonstrate that multiple aspects of psychopathology are significantly related to BI and can have broader implications for interventions and mental health care in autistic children.","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"17 12","pages":"2602-2613"},"PeriodicalIF":5.3,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0