Autism Research最新文献

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Autism Screening in the First Year and Beyond: Comparison of Multiple Measures 第一年及以后的自闭症筛查:多种措施的比较。
IF 3.9 2区 医学
Autism Research Pub Date : 2026-10-16 Epub Date: 2026-08-22 DOI: 10.1002/aur.70340
Devon N. Gangi, Chandni Parikh, Monique Moore Hill, Shyeena Maqbool, Rachel Ni, Simon Dvorak, Gregory S. Young, Sally Ozonoff
{"title":"Autism Screening in the First Year and Beyond: Comparison of Multiple Measures","authors":"Devon N. Gangi,&nbsp;Chandni Parikh,&nbsp;Monique Moore Hill,&nbsp;Shyeena Maqbool,&nbsp;Rachel Ni,&nbsp;Simon Dvorak,&nbsp;Gregory S. Young,&nbsp;Sally Ozonoff","doi":"10.1002/aur.70340","DOIUrl":"10.1002/aur.70340","url":null,"abstract":"<p>Autism screening aids in early detection and diagnosis. Several screeners are available for toddlers 16 months and older, but there is little data on the accuracy of screening measures used in the first year of life. A community sample (<i>N</i> = 1641) completed three screeners—M-CHAT-R, ITC, VIRSA—online at 6, 9, 12, 18, and 24 months of age (including exploratory use of M-CHAT-R prior to 16 months). At 36 months, outcomes of ASD or Non-ASD were determined by tele-evaluation and outcome surveys. Psychometric properties were assessed for all screeners at all ages, both used individually and in combination. When used in the first year of life (6–12 months), psychometric properties were in the poor range, with area under the curve (AUC) &lt; 0.70 for all three screeners, whether used in isolation or combination. At 18 and 24 months, the M-CHAT-R and ITC outperformed the VIRSA, with psychometric properties in the fair range (AUC 0.70–0.79) used in isolation and the good range (AUC ≥ 0.80) when used in combination. Using the M-CHAT-R and ITC at more than one age in the second year also fell in the good range. This study, using procedures to address limitations of prior screening studies and follow screen-negative cases, found that none of the three screeners had adequate psychometric properties in the first year. At 18 and 24 months, findings supported the use of multiple screeners, either in combination or longitudinally, for best prediction of autism diagnosis.</p>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 10","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13577608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148802281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impaired Motor Competence in Children and Adolescents With Autism Spectrum Disorder: Evidence From a Systematic Review and Meta-Analysis 自闭症谱系障碍儿童和青少年的运动能力受损:来自系统回顾和荟萃分析的证据。
IF 3.9 2区 医学
Autism Research Pub Date : 2026-10-16 Epub Date: 2026-08-17 DOI: 10.1002/aur.70347
Nerea Blanco-Martínez, Daniel González-Devesa, Silvia Varela, Rocío Carballo-Afonso, Carlos Ayán-Pérez
{"title":"Impaired Motor Competence in Children and Adolescents With Autism Spectrum Disorder: Evidence From a Systematic Review and Meta-Analysis","authors":"Nerea Blanco-Martínez,&nbsp;Daniel González-Devesa,&nbsp;Silvia Varela,&nbsp;Rocío Carballo-Afonso,&nbsp;Carlos Ayán-Pérez","doi":"10.1002/aur.70347","DOIUrl":"10.1002/aur.70347","url":null,"abstract":"<p>Autism spectrum disorder (ASD) is frequently associated with motor difficulties that may affect daily functioning, participation in physical activity, and developmental outcomes. Although motor impairments have been widely reported in this population, comparative evidence against typically developing (TD) peers remains fragmented across studies and assessment tools. This systematic review and meta-analysis aimed to examine whether children and adolescents with ASD show lower motor competence than TD peers and to identify the most affected motor domains. A systematic search was conducted in Scopus, Web of Science, PubMed, and SPORTDiscus up to December 10, 2025. Studies were eligible if they included children or adolescents with ASD and TD controls and assessed motor competence using standardized instruments. A total of 42 studies involving 3142 participants were included. The most frequently used tools were the Movement Assessment Battery for Children, the Bruininks–Oseretsky Test of Motor Proficiency, and the Test of Gross Motor Development. Across studies, children and adolescents with ASD consistently showed poorer performance than TD peers in manual dexterity, aiming and catching, balance, locomotor skills, and object control. Meta-analytic findings also indicated that participants with ASD had greater odds of presenting motor difficulty and being classified within the at-risk range. Despite heterogeneity and methodological limitations, the overall evidence supports a broad pattern of lower motor competence in ASD. These findings reinforce the importance of early motor assessment and targeted intervention in clinical and educational contexts.</p>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 10","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/aur.70347","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148802305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methodological Considerations for Interpreting a Short Eye-Tracking Paradigm for Autism Screening 解释自闭症筛查短眼动追踪范式的方法学考虑。
IF 3.9 2区 医学
Autism Research Pub Date : 2026-10-16 Epub Date: 2026-08-21 DOI: 10.1002/aur.70352
Ashith Tripathi, Raj Kumar, Krishan Kumar
{"title":"Methodological Considerations for Interpreting a Short Eye-Tracking Paradigm for Autism Screening","authors":"Ashith Tripathi,&nbsp;Raj Kumar,&nbsp;Krishan Kumar","doi":"10.1002/aur.70352","DOIUrl":"10.1002/aur.70352","url":null,"abstract":"","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 10","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148802330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inclusion of Participants With Limited English Proficiency in Autism Research 在自闭症研究中纳入英语水平有限的参与者。
IF 3.9 2区 医学
Autism Research Pub Date : 2026-10-16 Epub Date: 2026-08-25 DOI: 10.1002/aur.70331
Ava Weiran Lu, Cambrynne DeJong, Mary Grace Harris, Mariah Samuelle Johnson, Purnima Mudnal, Luis Rivas Vazquez, Yanira Belen Espinosa, Daniela Kotsonis, Maya I. Ragavan, Sarabeth Broder-Fingert, Marijane White, Katharine E. Zuckerman
{"title":"Inclusion of Participants With Limited English Proficiency in Autism Research","authors":"Ava Weiran Lu,&nbsp;Cambrynne DeJong,&nbsp;Mary Grace Harris,&nbsp;Mariah Samuelle Johnson,&nbsp;Purnima Mudnal,&nbsp;Luis Rivas Vazquez,&nbsp;Yanira Belen Espinosa,&nbsp;Daniela Kotsonis,&nbsp;Maya I. Ragavan,&nbsp;Sarabeth Broder-Fingert,&nbsp;Marijane White,&nbsp;Katharine E. Zuckerman","doi":"10.1002/aur.70331","DOIUrl":"10.1002/aur.70331","url":null,"abstract":"<div>\u0000 \u0000 <p>Individuals with autism spectrum disorder (ASD) and limited English proficiency (LEP), defined as having limited ability to read, write, or understand English, may experience disparities in quality of care and healthcare outcomes. However, little research has described methods and practices for including participants with LEP in ASD research studies. This literature review study investigated (1) the prevalence of LEP inclusion in U.S. research about ASD, (2) the languages included, and (3) the communication methods between research teams and participants with LEP. Using the Covidence Systematic Review Software, we completed a two-round screening of 1007 studies published between 2013 and June 2025 in four major autism journals: <i>Autism, Autism Research, Journal of Autism and Developmental Disorders,</i> and <i>Research in Autism Spectrum Disorders.</i> We limited the sample to U.S.-based original research involving human subjects with ASD and/or their caretakers. Eligible studies were reviewed further to extract relevant study information (e.g., participant demographics, study type, communication methods, and inclusion of LEP participants). Only 61 (19%) among the 326 eligible studies explicitly mentioned the inclusion of participants with LEP and provided information about their inclusion. Other studies may have included LEP participants but did not report their inclusion in the publication. The most common language included was Spanish. Results showed that the most used oral and written communication methods involved communication with, and translation of study materials by a bilingual research team member. The results suggest that LEP participants were underrepresented in ASD research, and future research is needed to advise more inclusive healthcare practices and policies for children and families.</p>\u0000 </div>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 10","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148815111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Grandparent Prenatal Tobacco, Alcohol, Coffee, and Tea Consumption and Autism in the Third Generation 祖父母产前烟草、酒精、咖啡和茶的消费与第三代自闭症
IF 3.9 2区 医学
Autism Research Pub Date : 2026-10-16 Epub Date: 2026-08-25 DOI: 10.1002/aur.70344
Michelle Pearl, Kimberly Berger, Piera M. Cirillo, Nickilou Y. Krigbaum, Victor Poon, Gayle C. Windham, Barbara A. Cohn
{"title":"Grandparent Prenatal Tobacco, Alcohol, Coffee, and Tea Consumption and Autism in the Third Generation","authors":"Michelle Pearl,&nbsp;Kimberly Berger,&nbsp;Piera M. Cirillo,&nbsp;Nickilou Y. Krigbaum,&nbsp;Victor Poon,&nbsp;Gayle C. Windham,&nbsp;Barbara A. Cohn","doi":"10.1002/aur.70344","DOIUrl":"https://doi.org/10.1002/aur.70344","url":null,"abstract":"<p>Exogenous prenatal exposures may affect neurodevelopment across multiple generations. We investigated grandmother and grandfather smoking, alcohol, coffee, and tea consumption during pregnancy in relation to their grandchildren's risk of autism spectrum disorder (ASD). Pregnant participants (grandparent generation) in the Child Health and Development Studies (CHDS) were interviewed between 1959 and 1967 about their own and their partners' smoking and consumption of alcohol, coffee, and tea. CHDS participant records were linked to 18,053 third-generation California births from 1989 to 2014, from which ASD cases were identified from Department of Developmental Services records. We estimated adjusted relative risk (aRR) of ASD associated with grandparents' smoking and consumption of alcoholic beverages, coffee, and tea from log-binomial regression models adjusted for grandparents' age, education, and grandmother's race. Grandfather's overall tobacco smoking (including pipes and cigars) during their partner's pregnancy was related to grandchild ASD (aRR = 1.76, 95% confidence interval [1.05, 2.96]), as was grandfathers' cigarette smoking (aRR = 1.67 [1.01, 2.76]), particularly smoking 20 or more cigarettes per day (aRR = 1.91 [1.03, 3.55]), relative to no smoking. Alcohol consumption of five or more drinks of hard liquor per week by grandfathers was associated with ASD in grandchildren (aRR = 2.90 [1.24, 6.79], relative to none), as was total consumption of nine or more total alcoholic drinks (aRR = 1.87 [1.00, 3.51] relative to &lt; 9). Coffee consumption and combined coffee and tea consumption by either grandparent were not associated with grandchild ASD. Findings support the hypothesis that grandfather exposures around the time of offspring conception are linked to grandchild autism.</p>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 10","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/aur.70344","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149206172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of Anticholinergic Medication Use and Its Associations With Everyday Memory Problems and Cognitive Decline in Autistic Adults With Higher Support Needs 抗胆碱能药物使用的特征及其与高支持需求自闭症成人日常记忆问题和认知能力下降的关系。
IF 3.9 2区 医学
Autism Research Pub Date : 2026-10-16 Epub Date: 2026-08-13 DOI: 10.1002/aur.70342
Goldie A. McQuaid, Nancy Raitano Lee, Gregory L. Wallace
{"title":"Characterization of Anticholinergic Medication Use and Its Associations With Everyday Memory Problems and Cognitive Decline in Autistic Adults With Higher Support Needs","authors":"Goldie A. McQuaid,&nbsp;Nancy Raitano Lee,&nbsp;Gregory L. Wallace","doi":"10.1002/aur.70342","DOIUrl":"10.1002/aur.70342","url":null,"abstract":"<p>Among older adults in the general population, medications with anticholinergic (AC) effects are associated with declines in cognitive functioning and with dementia and Alzheimer's disease. Autistic people have high rates of co-occurring medical conditions and polypharmacy across the lifespan; thus, they may be at particularly high risk of exposure to AC medications and their negative impacts on cognitive functioning, including earlier in adulthood. Consistent with this, a single study has shown AC medication use is prevalent among autistic adults without co-occurring intellectual disability and is associated with self-reported concurrent memory problems and declines in cognition. No study has examined AC medications and their associations with cognition among autistic adults with higher support needs. We therefore characterized AC medication use and its associations with caregiver-rated memory problems and changes in cognition and behavior that have been linked with cognitive decline. Caregivers of autistic adults (18–68 years; Mean ~31 years) recruited via Simons Powering Autism Research's (SPARK) Research Match service reported medication use (<i>N</i> = 512), memory complaints (<i>N</i> = 467), and a screener that probes behavior/cognitive changes (<i>N</i> = 466) that are associated with cognitive decline among persons with an intellectual disability. The majority (66.41%) of autistic adults were taking at least one AC medication and 31% were taking clinically-meaningful levels of these medications. After controlling for age and birth sex, greater potency of AC medications was associated with both caregiver-reported memory challenges and behavioral/cognitive changes associated with cognitive decline. Understanding AC medication use and its potential impacts on cognition among autistic adults with higher support needs is crucial.</p>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 10","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/aur.70342","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148727464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antidepressant Prescribing Trends for Adults With and Without Autism in the United Kingdom From 1997 to 2023: A Population-Based Cohort Study Using Clinical Practice Research Datalink Aurum 从1997年到2023年,英国有和没有自闭症的成年人的抗抑郁药处方趋势:一项基于人群的队列研究,使用临床实践研究数据链Aurum
IF 3.9 2区 医学
Autism Research Pub Date : 2026-10-16 Epub Date: 2026-08-27 DOI: 10.1002/aur.70360
Aws Sadik, Golam M. Khandaker, Antonio F. Pardiñas, Michael Lundberg, Brian K. Lee, Cecilia Magnusson, Dheeraj Rai, Paul Madley-Dowd
{"title":"Antidepressant Prescribing Trends for Adults With and Without Autism in the United Kingdom From 1997 to 2023: A Population-Based Cohort Study Using Clinical Practice Research Datalink Aurum","authors":"Aws Sadik,&nbsp;Golam M. Khandaker,&nbsp;Antonio F. Pardiñas,&nbsp;Michael Lundberg,&nbsp;Brian K. Lee,&nbsp;Cecilia Magnusson,&nbsp;Dheeraj Rai,&nbsp;Paul Madley-Dowd","doi":"10.1002/aur.70360","DOIUrl":"10.1002/aur.70360","url":null,"abstract":"<p>Antidepressant prescribing and autism diagnoses have increased in recent years. We aimed to describe and compare trends in antidepressant prescribing, indications, doses and durations in autistic and non-autistic males and females in the United Kingdom (UK) from 1997 to 2023. Using population-representative UK primary care records, we defined three autistic groups—autistic adults with intellectual disability (ID), autistic adults without ID and all autistic adults—and four non-autistic groups. In each calendar year we calculated: annual, lifetime and new antidepressant prescribing; indications for serotonin-selective reuptake inhibitor initiation; average doses prescribed for citalopram, fluoxetine, and sertraline; and the proportion of courses that lasted over 1, 2, and 3 years. We also repeated analyses with sex-stratification. In all, 34,173,295 non-autistic adults and 172,242 autistic adults were included (47,011 with ID and 125,231 without ID). 30% of autistic adults and 14.7% of non-autistic adults were prescribed an antidepressant in 2023. Prescriptions, doses and course durations increased over time for all groups. Prescriptions were highest in autistic adults without ID and females, whereas course durations were highest in autistic adults with ID. Recording of depression and anxiety as indications was lower for those with ID. Antidepressant prescribing has increased more for autistic adults than non-autistic adults since 1997, with more new starters, higher doses and longer course durations. This potentially increases the risk of adverse medication effects for autistic adults and emphasizes the need for stronger evidence around the effectiveness and tolerability of mental health interventions and the reasons for systematic differences in prescribing.</p>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 10","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/aur.70360","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148835089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Social Pain Sensitivity in Autistic Adults: Associations With Gender, Self-Esteem, Cognitive Empathy, and Sensory Sensitivity 自闭症成人的社会疼痛敏感性:与性别、自尊、认知共情和感觉敏感性的关系。
IF 3.9 2区 医学
Autism Research Pub Date : 2026-10-16 Epub Date: 2026-08-13 DOI: 10.1002/aur.70345
Alvin van Asselt, Yvette Roke, Sander Begeer, Anke Scheeren
{"title":"Social Pain Sensitivity in Autistic Adults: Associations With Gender, Self-Esteem, Cognitive Empathy, and Sensory Sensitivity","authors":"Alvin van Asselt,&nbsp;Yvette Roke,&nbsp;Sander Begeer,&nbsp;Anke Scheeren","doi":"10.1002/aur.70345","DOIUrl":"10.1002/aur.70345","url":null,"abstract":"<div>\u0000 \u0000 <p>Social pain sensitivity refers to the tendency to detect and react strongly to cues of social exclusion. Frequent social adversities and specific characteristics may make individuals with autism more sensitive to social pain, yet evidence remains inconsistent. To enhance our understanding, autistic adults aged ≥ 16 years (<i>n</i> = 1425; <i>M</i><sub>age</sub> = 47.3, SD = 14.2) and allistic adults (<i>n</i> = 187; <i>M</i><sub>age</sub> = 51.4, SD = 14.6) enrolled in the Netherlands Autism Register (NAR) completed the Social Pain Questionnaire (SPQ). A two-way ANOVA demonstrated that autistic adults reported significantly higher social pain sensitivity than allistic adults, with a small effect size (<i>η</i><sup>2</sup><i><sub>p</sub></i> = 0.02). Women reported higher social pain sensitivity than men across both groups (<i>η</i><sup>2</sup><i><sub>p</sub></i> = 0.01), and this gender difference was comparable for autistic and allistic adults. Within the autistic group, in a subset of participants with complete data (<i>n</i> = 234), a hierarchical multiple regression analysis showed that social pain sensitivity was moderately associated with lower self-esteem (<i>β</i> = −0.47), but not with cognitive empathy or sensory sensitivity. Exploratory analyses further indicated that self-esteem fully accounted for the association between autism diagnosis and social pain sensitivity. Consistent with sociometer theory, these results suggest that heightened social pain sensitivity in autistic adults may reflect reduced perceived social acceptance. Our findings highlight the relevance of social adversities for autistic adults and underscore the need for supports that strengthen belonging and reduce socially painful experiences.</p>\u0000 </div>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 10","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148727562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Empathy Moderates the Association Between Social Disengagement and Emotion Problems in Autistic Youth 共情调节自闭症青少年社交脱离与情绪问题的关系。
IF 3.9 2区 医学
Autism Research Pub Date : 2026-10-16 Epub Date: 2026-08-31 DOI: 10.1002/aur.70341
Lacey Chetcuti, Emily Spackman, Eva Loth, Emma Baker, Antonio Y. Hardan, Mirko Uljarevic
{"title":"Empathy Moderates the Association Between Social Disengagement and Emotion Problems in Autistic Youth","authors":"Lacey Chetcuti,&nbsp;Emily Spackman,&nbsp;Eva Loth,&nbsp;Emma Baker,&nbsp;Antonio Y. Hardan,&nbsp;Mirko Uljarevic","doi":"10.1002/aur.70341","DOIUrl":"10.1002/aur.70341","url":null,"abstract":"<div>\u0000 \u0000 <p>Social disengagement and empathizing difficulties are common in autism and have been linked to various socioemotional outcomes. Yet, their relationship remains understudied. This study addresses this gap by examining associations among different forms of social disengagement and empathy in autistic children and adolescents, as well as their interactive effects in predicting concurrent emotion problems. Parents of 689 autistic youth aged 5–17 years (<i>M</i> [SD] = 11.23 [3.56]; 76% male) completed questionnaires: the Child Social Preference Scale assessed shyness, unsociability, and social avoidance; the Children's Empathy Quotient measured cognitive and affective empathy; and the Strengths and Difficulties Questionnaire assessed emotion problems. Results showed that all forms of social disengagement were associated with difficulties in both cognitive and affective empathy, with social avoidance showing the strongest associations. Furthermore, the interplay between different forms of social disengagement and empathy contributed to variability in emotion problems. Specifically, the links between unsociability and social avoidance and elevated emotion problems were stronger among youth with higher levels of empathy. In contrast, the positive association between shyness and emotion problems was not influenced by empathy. These findings underscore the importance of considering the multifaceted nature of social disengagement and its association with empathy, offering directions for future research.</p>\u0000 </div>","PeriodicalId":131,"journal":{"name":"Autism Research","volume":"19 10","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148868136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Cannabidiol-Rich Cannabis Oil on Facial Expression Recognition and Theory of Mind in Children With Autism Spectrum Disorder: A Randomized Clinical Trial 富含大麻二酚的大麻油对自闭症谱系障碍儿童面部表情识别和心理理论的影响:一项随机临床试验。
IF 3.9 2区 医学
Autism Research Pub Date : 2026-10-16 Epub Date: 2026-08-26 DOI: 10.1002/aur.70353
Wandersonia Moreira Brito Medeiros, Estácio Amaro da Silva Junior, Katy Lísias Gondim Dias de Albuquerque, Marine Diniz da Rosa, Amanda Gleiciane de Lima Oliveira, Maycon Jônatas da Silva, João Vitor Andrade Fernandes, Emily Caroline Costa Vieira, João Paulo Mendes dos Santos, Thais Cavalcanti Borges, Ana Hermínia Andrade e Silva, Carlos Espínola Neto Segundo, Nelson Torro-Alves
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