Human Fertility最新文献_第7页

The role of myo-inositol supplement in assisted reproductive techniques. 肌醇补充剂在辅助生殖技术中的作用。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2022-06-22 DOI: 10.1080/14647273.2022.2073273

Zahra Bashiri, Nadia Sheibak, Fatemehsadat Amjadi, Zahra Zandieh

{"title":"The role of myo-inositol supplement in assisted reproductive techniques.","authors":"Zahra Bashiri, Nadia Sheibak, Fatemehsadat Amjadi, Zahra Zandieh","doi":"10.1080/14647273.2022.2073273","DOIUrl":"10.1080/14647273.2022.2073273","url":null,"abstract":"Assisted reproductive techniques can help many infertile couples conceive. Therefore, there is a need for an effective method to overcome the widespread problems of infertile men and women. Oocyte and sperm quality can increase the chances of successful in vitro fertilisation. The maturation environment in which gametes are present can affect their competency for fertilisation. It is well established that myo-inositol (MI) plays a pivotal role in reproductive physiology. It participates in cell membrane formation, lipid synthesis, cell proliferation, cardiac regulation, metabolic alterations, and fertility. This molecule also acts as a direct messenger of insulin and improves glucose uptake in various reproductive tissues. Evidence suggests that MI regulates events such as gamete maturation, fertilisation, and embryo growth through intracellular Ca2 + release and various signalling pathways. In addition to the in-vivo production of MI from glucose in the reproductive organs, its synthesis by in vitro-cultured sperm and follicles has also been reported. Therefore, MI is suggested as a therapeutic approach to maintain sperm and oocyte health in men and women with reproductive disorders and individuals of reproductive age.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40177656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Comparison of spermatic and peripheral blood gases and their correlation with spermogram pattern and varicocele grade in patients with a varicocele. 精索静脉曲张患者精子和外周血气的比较及其与精子图模式和精索静脉曲张分级的相关性。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2022-03-10 DOI: 10.1080/14647273.2022.2046294

Hossein Dialameh, Farshad Namdari, Mohammad Javad Nazarpour, Mahdi Gouravani, Mehrdad Mahalleh, Masoud Bahoush, Alireza Marjooee, Mahdi Ramezani-Binabaj, Mohammad Reza Nikoobakht, Mahsa Kiani

{"title":"Comparison of spermatic and peripheral blood gases and their correlation with spermogram pattern and varicocele grade in patients with a varicocele.","authors":"Hossein Dialameh, Farshad Namdari, Mohammad Javad Nazarpour, Mahdi Gouravani, Mehrdad Mahalleh, Masoud Bahoush, Alireza Marjooee, Mahdi Ramezani-Binabaj, Mohammad Reza Nikoobakht, Mahsa Kiani","doi":"10.1080/14647273.2022.2046294","DOIUrl":"10.1080/14647273.2022.2046294","url":null,"abstract":"The relationship between infertility and varicocele is still a controversial topic. This study aimed to find the association between the venous blood gas (VBG) pattern of the spermatic veins and peripheral veins with varicocele grade and spermogram variables in infertile patients. A total of 47 patients with a varicocele were enrolled in this study. Blood samples were drawn simultaneously from the spermatic vein and a peripheral vein. The pH, partial pressure of oxygen, the partial pressure of carbon dioxide, oxygen saturation, and bicarbonate values of these samples were analysed. The mean age of participants was 30.48 ± 6.08. The mean volume of semen was 3.92 ± 1.57 mL, and the mean semen pH was 7.88 ± 0.22. The pH was higher (p < 0.01) in the spermatic vein compared with the peripheral vein. However, level of other parameters including pO2 (p = 0.662), pCO2 (p < 0.001), HCO3 concentration of serum (p < 0.01), and base excess (p = 0.172) were lower in the spermatic vein in comparison with the peripheral vein. Correlations between VBGs determinants of the varicocele patients' spermatic vein and sperm morphology and motility were insignificant. In conclusion, although the clinical significance of VBGs is evident, there are limited studies that investigated the VBGs in varicocele patients. We should consider that the deviation in blood gases may be the missing piece in the puzzle to understand the pathophysiology of varicocele. By knowing the pathophysiology more precisely, we can better decide the ideal treatment option for the patients.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44341398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The associations of cola intake with adverse birth outcomes among pregnant women after assisted reproductive technology treatment and women naturally conceived: a birth cohort study. 辅助生殖技术治疗后孕妇和自然受孕妇女的可乐摄入量与不良出生结果的关系：一项出生队列研究。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2024-01-22 DOI: 10.1080/14647273.2023.2286347

Can Shen, Ruirui Hou, Xiaoyue Zhang, Guoqi Cai, Chunmei Liang, Hong Gan, Xiaofeng Xu, Huifen Xiang, Fangbiao Tao, Yunxia Cao, Xiaoqing Peng

{"title":"The associations of cola intake with adverse birth outcomes among pregnant women after assisted reproductive technology treatment and women naturally conceived: a birth cohort study.","authors":"Can Shen, Ruirui Hou, Xiaoyue Zhang, Guoqi Cai, Chunmei Liang, Hong Gan, Xiaofeng Xu, Huifen Xiang, Fangbiao Tao, Yunxia Cao, Xiaoqing Peng","doi":"10.1080/14647273.2023.2286347","DOIUrl":"10.1080/14647273.2023.2286347","url":null,"abstract":"The influence of cola intake on birth outcomes is unclear. This study sought to describe and compare the associations between cola intake and adverse birth outcomes among women following assisted reproductive technology (ART) and women spontaneously conceived (SC). Participants (736 ART women and 1,270 SC women) were from the Chinese National Birth Cohort collected in Anhui province. Cola intake was assessed by self-reported questionnaires at each trimester. Outcome measures including preterm birth (PTB) and low birth weight (LBW) were extracted from medical records. The association between cola intake during pregnancy and PTB was found using multivariable log-binomial regression in combined ART and SC women. Separately, for ART women, cola intake during pregnancy increased the risk of PTB (risk ratios were 2.10, 1.65, and 1.81 for all three trimesters, respectively, all p < 0.05), and cola intake in the 1st trimester increased the risk of LWB (risk ratio 2.58, 95% confidence interval 1.29 to 5.16). Cola intake during pregnancy was not associated with PTB or LBW for SC women. Our findings indicate a detrimental effect of cola intake during pregnancy on birth outcomes for ART women. Thus, avoidance of cola intake should be counselled by medical doctors in women prescribed with ART treatment.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139512292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing infertility-related stress, coping, and quality of life among assisted reproductive technology and non-assisted reproductive technology treatments. 比较辅助生殖技术治疗和非辅助生殖技术治疗中与不孕症有关的压力、应对方法和生活质量。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2023-01-04 DOI: 10.1080/14647273.2022.2163465

Alison Swift, Pamela Reis, Melvin Swanson

{"title":"Comparing infertility-related stress, coping, and quality of life among assisted reproductive technology and non-assisted reproductive technology treatments.","authors":"Alison Swift, Pamela Reis, Melvin Swanson","doi":"10.1080/14647273.2022.2163465","DOIUrl":"10.1080/14647273.2022.2163465","url":null,"abstract":"Women who undergo assisted reproductive technology (ART) treatments experience infertility-related stress and have low quality of life (QOL). However, there is limited understanding of infertility-related stress, coping, or QOL among women who undergo non-ART treatments. The purpose of this study was to examine infertility-related stress, coping, and QOL among women who undergo ART and non-ART infertility treatments. Using a descriptive correlational cross-sectional design, we recruited 200 women who underwent infertility treatments. Participants completed the Copenhagen Multi-centre Psychosocial Infertility (COMPI) Fertility Problem Stress Scale, COMPI Coping Styles Scale, Fertility Quality of Life tool, and a demographic infertility survey. Data analysis included descriptive statistics, independent t-test, chi-square, and hierarchical multiple regression. Women who underwent non-ART had more personal stress, used more active-avoidance coping, and had lower emotional, social, and treatment environment QOL compared to those in ART treatment. Women who underwent ART treatments used more meaning-based coping but had lower treatment tolerability QOL. Stress and coping contribute to core QOL differently among infertility treatment groups. Both treatment groups report low satisfaction with emotional services. Regardless of the treatment type, women who undergo infertility treatments may need care to address their psychological health.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10533206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Comparison of the efficacy of depot GnRH agonist protocol and the GnRH antagonist protocol in patients with repeated IVF failure: a retrospective cohort study. 反复试管婴儿失败患者使用去势 GnRH 激动剂方案和 GnRH 拮抗剂方案的疗效比较：一项回顾性队列研究。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2023-03-22 DOI: 10.1080/14647273.2023.2175267

Tingting Li, Xiaoping Liu, Xing Yang, Ningning Wang, Yanfang Wang, Wei Li, Xiaoyan Liang, Rui Huang

{"title":"Comparison of the efficacy of depot GnRH agonist protocol and the GnRH antagonist protocol in patients with repeated IVF failure: a retrospective cohort study.","authors":"Tingting Li, Xiaoping Liu, Xing Yang, Ningning Wang, Yanfang Wang, Wei Li, Xiaoyan Liang, Rui Huang","doi":"10.1080/14647273.2023.2175267","DOIUrl":"10.1080/14647273.2023.2175267","url":null,"abstract":"The aims of the research were (i) to compare the clinical outcome of IVF using follicular-phase depot gonadotropin-releasing hormone (GnRH) agonist (depot agonist) protocol and GnRH antagonist protocol in patients with repeated IVF failure (RIF), (ii) to discover the optimal ovarian stimulation protocol for this group of low prognosis patients. 801 RIF patients with normal ovarian reserve receiving in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) were included in this retrospective study. Among them, 492 patients were treated with the depot agonist protocol, and the remaining 309 patients with the antagonist protocol. Multivariable logistic regression analysis was used to find the predictor(s) of the chance of live birth. Higher live birth rate (LBR) and clinical pregnancy rate (CPR) in fresh embryo transfer (ET) cycles were associated with the use of depot agonist compared with the antagonist protocols (44.81% vs. 27.27%, 54.64% vs. 34.93%, respectively; both p < 0.01) and depot agonist protocol was a strong predictor of live birth (OR = 2.182, 95% CI 1.355-3.514, p < 0.01). The CPR in thawed ET cycles was not significantly different between the two groups (38.12% vs. 45.26%, p > 0.05). A higher cumulative live birth rate (CLBR) was achieved in the depot agonist group (46.59% vs. 35.21%, p < 0.01). Beneficial endometrial receptivity in the depot agonist protocol contributed to a higher LBR in fresh ET cycles, rendering this protocol the preferred option in the treatment of RIF patients.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9156736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gene pathway analysis of the endometrium at the start of the window of implantation in women with unexplained infertility and unexplained recurrent pregnancy loss: is unexplained recurrent pregnancy loss a subset of unexplained infertility? 不明原因不孕症和不明原因复发性妊娠丢失妇女植入窗口期子宫内膜的基因通路分析：不明原因复发性妊娠丢失是不明原因不孕症的一个子集吗？

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2022-11-12 DOI: 10.1080/14647273.2022.2143299

Irem Demiral Keleş, Tuba Günel, Bahar Yüksel Özgör, Ege Ülgen, Ece Gümüşoğlu, Mohammad Kazem Hosseini, Uğur Sezerman, Faruk Buyru, John Yeh, Ercan Baştu

{"title":"Gene pathway analysis of the endometrium at the start of the window of implantation in women with unexplained infertility and unexplained recurrent pregnancy loss: is unexplained recurrent pregnancy loss a subset of unexplained infertility?","authors":"Irem Demiral Keleş, Tuba Günel, Bahar Yüksel Özgör, Ege Ülgen, Ece Gümüşoğlu, Mohammad Kazem Hosseini, Uğur Sezerman, Faruk Buyru, John Yeh, Ercan Baştu","doi":"10.1080/14647273.2022.2143299","DOIUrl":"10.1080/14647273.2022.2143299","url":null,"abstract":"This study aims to understand differences/similarities in the genetic profile of the endometrium at the start of window of implantation (WOI) in women with unexplained infertility (UI) and unexplained recurrent pregnancy loss (uRPL). Differentially expressed genes (DEGs) from the endometrium were evaluated using gene expression array and pathway enrichment analysis was performed to analyse gene expression pathways involved in both conditions. We found 2,171 genes arranged in 117 pathways and 730 genes arranged in 33 pathways differentially expressed in endometrium of patients in UI and uRPL, respectively. Complement-coagulation cascades, morphine addiction pathway, and PI3K-Akt signalling pathway were predominantly differentially expressed in UI. Cancer pathways, NF-κB signalling pathway, and actin cytoskeleton regulation pathway showed significant changes in uRPL. Forty-eight percent of DEGs and 84% of differentially expressed pathways in uRPL were found in the endometrium of UI patients. Unexpected close association in gene expression pathways between UI and uRPL is observed supporting the hypothesis 'uRPL is a clinical subset of UI'. Yet 100% DEGs overlap wasn't found suggesting the endometrium has still some different gene expression patterns at start of WOI in UI and uRPL. Lastly, diagnostic tools may be developed for uRPL because more specific genes-pathways are involved compared with UI, which shows broader genetic expression profile.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40473109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Recombinant human granulocyte colony stimulating factor (rhG-CSF) participates in the progression of implantation via the hsa_circ_0001550-miRNA-mRNA interaction network. 重组人粒细胞集落刺激因子（rhG-CSF）通过 hsa_circ_0001550-miRNA-mRNA 相互作用网络参与植入过程。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2022-07-06 DOI: 10.1080/14647273.2022.2093137

Meng Lyu, Anchen Su, Lili Zhang, Wenxin Gao, Kun Liu, Feng Yue, Yuanxue Jing, Xiaoling Ma, Lin Liu

{"title":"Recombinant human granulocyte colony stimulating factor (rhG-CSF) participates in the progression of implantation via the hsa_circ_0001550-miRNA-mRNA interaction network.","authors":"Meng Lyu, Anchen Su, Lili Zhang, Wenxin Gao, Kun Liu, Feng Yue, Yuanxue Jing, Xiaoling Ma, Lin Liu","doi":"10.1080/14647273.2022.2093137","DOIUrl":"10.1080/14647273.2022.2093137","url":null,"abstract":"Inadequate endometrial receptivity is a key factor affecting the successful implantation of embryos. Recombinant human granulocyte colony stimulating factor (rhG-CSF) can increase endometrial thickness and improve the outcomes of assisted reproductive technologies (ARTs). In this preliminary study, the function and possible molecular mechanisms of recombinant human granulocyte colony stimulating factor (rhG-CSF) which affects endometrial receptivity and implantation in human Embryonic Stem Cells (hESCs) were investigated. The cell viability of endometrial stromal cells treated with rhG-CSF 0.5 ng/ml for 24 h was significantly increased. Moreover, the expression of hsa_circ_0001550 was downregulated in endometrial stromal cells treated with rhG-CSF. Furthermore, the hsa_circ_0001550-miRNA-mRNA network was constructed and the downstream target genes (including 4 miRNAs and 117 mRNAs) of hsa_circ_0001550 were mainly involved in the cAMP and calcium signalling pathways, which play important roles in regulating endometrial receptivity and embryo implantation. We conclude that rhG-CSF participates in the regulation of embryo implantation by regulating the hsa_circ_0001550-miRNA-mRNA interaction network.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40474616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2022-01-05 DOI: 10.1080/14647273.2021.2021454

Yi Liu, Xiubing Zhang, Yan Xu, Rong Li, Bing Cai, Chenhui Ding, Canquan Zhou, Yanwen Xu

{"title":"Similar implantation competence in euploid blastocysts developed on day 5 or day 6 in young women: a retrospective cohort study.","authors":"Yi Liu, Xiubing Zhang, Yan Xu, Rong Li, Bing Cai, Chenhui Ding, Canquan Zhou, Yanwen Xu","doi":"10.1080/14647273.2021.2021454","DOIUrl":"10.1080/14647273.2021.2021454","url":null,"abstract":"The results from different studies are inconsistent regarding whether development potential correlated with embryo development speed after single euploid blastocyst transfer. The age-associated reproductive decline is not only because of the difference in aneuploidy rates but also because of metabolic and epigenetic changes of the embryos. Therefore, we aimed to assess the independent effect of embryo development speed on implantation potential in young women. A total of 326 young women who underwent preimplantation genetic testing for monogenic diseases with aneuploidy screening were analyzed. Day-5 and day-6 euploid blastocysts yielded similar implantation rates (65.20 vs. 61.22%). The odds ratio (OR) remained non-significant after adjusting for confounders (adjusted OR = 0.84, 95% confidence interval 0.52-1.36). There was a trend that day-6 euploid blastocysts had a higher miscarriage rate (13.33 vs. 9.20%). However, the live birth delivery rate of day-5 blastocysts was similar to that of day-6 blastocysts (59.20 vs. 53.06%). In the stratified analysis, live birth delivery rates were similar between day-5 and day-6 similarly graded euploid blastocysts (excellent and good, 62.04 vs. 64.71%; average, 58.73 vs. 53.70%; poor, 43.75 vs. 44.44%). Embryo development speed has no obvious impact on implantation competence in young women's vitrified/warmed euploid embryo transfer cycles.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39786509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical features of isolated Fallopian tube torsion: evidence from a large series. 孤立性输卵管扭转的临床特征：来自大型系列研究的证据。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2022-02-04 DOI: 10.1080/14647273.2022.2034056

Raanan Meyer, Nir Meller, Aya Mohr-Sasson, Shlomo Toussia-Cohen, Ronit Machtinger, Yossi Bart, Roy Mashiach, Gabriel Levin

{"title":"Clinical features of isolated Fallopian tube torsion: evidence from a large series.","authors":"Raanan Meyer, Nir Meller, Aya Mohr-Sasson, Shlomo Toussia-Cohen, Ronit Machtinger, Yossi Bart, Roy Mashiach, Gabriel Levin","doi":"10.1080/14647273.2022.2034056","DOIUrl":"10.1080/14647273.2022.2034056","url":null,"abstract":"We aimed at studying isolated Fallopian tube torsion (IFTT) in a relatively large cohort of women and to evaluate different features of IFTT in comparison to a large cohort of women with non-IFTT adnexal torsion (NIAT). This was a retrospective cohort study. We included women with surgically confirmed ovarian and/or Fallopian tube torsion between March 2011 and June 2020. Fifty-four cases of IFTT were surgically confirmed during the study period and were compared to 422 surgically confirmed NIAT. The rate of controlled ovarian hyperstimulation treatments, current pregnancy, and vomiting was lower in the IFTT group compared with the NIAT group. Cervical tenderness and vaginal discharge were more common in the IFTT group. Oedematous and enlarged ovaries were less common in the IFTT group. In multivariate regression analysis, the following factors were independently associated with IFTT: (i) vaginal discharge [adjusted odds ratio (aOR) 95% CI 8.16, 1.98-33.55]; (ii) cervical motion tenderness (aOR 95% CI 2.71, 1.01-7.29); (iii) fertility treatments (aOR 95% CI 0.26, 0.70-0.77); (iv) previous abdominal surgery (aOR 95% CI 0.46, 0.22-0.96); (v) vomiting (aOR 95% CI 0.38, 0.19-0.76); and (vi) enlarged ovary (aOR 95% CI 0.34, 0.18-0.65). In conclusion, we have identified factors positively and negatively associated with IFTT in a large cohort of women with adnexal torsion.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39885263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Estimation of follicular growth-widely used, seldom studied. 卵泡生长的估计--广泛使用，很少研究。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2022-11-18 DOI: 10.1080/14647273.2022.2145916

Ido Feferkorn, Eva Suarthana, Hormoz Nassiri Kigloo, Einav Kadour Peero, Ranit Hizkiyahu, William Buckett

{"title":"Estimation of follicular growth-widely used, seldom studied.","authors":"Ido Feferkorn, Eva Suarthana, Hormoz Nassiri Kigloo, Einav Kadour Peero, Ranit Hizkiyahu, William Buckett","doi":"10.1080/14647273.2022.2145916","DOIUrl":"10.1080/14647273.2022.2145916","url":null,"abstract":"We assessed whether estimation of follicular growth, rather than actual measurement of follicular size on the day of hCG trigger, affected pregnancy rates in intrauterine insemination (IUI) cycles. Patient and cycle characteristics were extracted from an existing database. Comparisons were made between the pregnant (defined as a positive beta hCG) and non-pregnant groups for the following variables: patient's age, number of previous IUI cycles, type of ovarian stimulation, endometrial thickness, number of follicles measuring 14 mm and above, pre and post wash sperm parameters, cycle day when IUI was done and number of days between last ultrasound scan and ovulation trigger. A total of 7302 cycles were included in the final analysis. In 4055 cycles (55.5%) the hCG trigger was on the day of the last ultrasound, in 2285 cycles (31.3%) the hCG trigger was 1 day after the last ultrasound, in 850 (11.6%) it was 2 days after the last ultrasound and in 112 (1.5%) it was 3 or more days after the last ultrasound. Sperm parameters, younger maternal age, and the number of follicles above 14 mm were all associated with pregnancy. No association was found between positive pregnancy test rates and the time from last ultrasound to hCG trigger. Planning IUI based on the estimation of follicular growth 1-4 days before trigger, does not affect pregnancy rates.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40484353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0