Human Fertility最新文献_第10页

Should women with high body mass index be denied fertility treatments? 体重指数高的女性是否应该被拒绝接受生育治疗？

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2023-08-01 DOI: 10.1080/14647273.2022.2152741

Sadaf Shaikh, Garima Srivastava, Roy Homburg

引用次数: 0

Psychological distress in infertile women: the role of quality of marital relationships and self-compassion. 不孕妇女的心理困扰：婚姻关系质量和自我同情的作用。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2023-06-24 DOI: 10.1080/14647273.2023.2222547

Mehrdad Hajihasani, Raziyeh Ekhtiari Amiri

{"title":"Psychological distress in infertile women: the role of quality of marital relationships and self-compassion.","authors":"Mehrdad Hajihasani, Raziyeh Ekhtiari Amiri","doi":"10.1080/14647273.2023.2222547","DOIUrl":"10.1080/14647273.2023.2222547","url":null,"abstract":"Infertility is a common disease. At least 10-15% of women deal with infertility in some way. Infertile women suffer from a higher degree of psychological distress compared to fertile women. This study aims to identify the role of the quality of marital relationships and self-compassion in psychological distress in infertile women. The participants were 400 women who were referred to fertility clinics in Iran over a two-year period. Questionnaires containing Demographic Questionnaire, Psychological Distress Scale (DASS), Marital Quality Scale (MQS) and Self-Compassion Scale (MCS). The results showed that predictor variables explain a total of 29.9% of the variance of psychological distress in infertile women. The quality of marital relationships (p = 0.001 and β = -0.49) and self-compassion (p < 0.05 and β = -0.08) can negatively predict the psychological distress of infertile women. Considering that the significant role of the quality of marital relationships and self-compassion in the psychological distress of infertile women has been confirmed; therefore, interventions that focus on the quality of marital relationships and self-compassion may be effective and should be used as a resource to combat psychological distress in infertile women.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10053456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Y-chromosome haplogroups and Azoospermia Factor (AZF) analysis in Tunisian infertile male. 突尼斯不育男性的 Y 染色体单倍群和无精子症因子（AZF）分析。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2023-01-02 DOI: 10.1080/14647273.2022.2163194

Myriam Ghorbel, Siwar Baklouti-Gargouri, Rim Keskes, Afifa Sellami, Ken McElreavy, Leila Ammar-Keskes

{"title":"Y-chromosome haplogroups and Azoospermia Factor (AZF) analysis in Tunisian infertile male.","authors":"Myriam Ghorbel, Siwar Baklouti-Gargouri, Rim Keskes, Afifa Sellami, Ken McElreavy, Leila Ammar-Keskes","doi":"10.1080/14647273.2022.2163194","DOIUrl":"10.1080/14647273.2022.2163194","url":null,"abstract":"The aim of the present study was to clarify the implication of Y chromosome genetic variations and haplogroups in Tunisian infertile men. A total of 27 Y-chromosomal binary markers partial microdeletions (gr/gr, b1/b3 and b2/b3) and copy number variation of DAZ and CDY genes in the AZFc region were analysed in 131 Tunisian infertile men with spermatogenic failure and severe reduced sperm concentrations and in 85 normospermic men as controls. Eleven different haplogroups in the overall population study (E3b2; J1J*, E1, E3b*, F, G, K, P/Q, R*, R1* and R1a1) were found. Interestingly, the J1J* haplogroup was significantly more frequent in azoo/oligospermic patients than in normospermic men (35.1% and 22.3%, respectively (p value = 0.04)). Results showed also that patients without DAZ/CDY1 copies loss and without partial microdeletions belonged to the R1 haplogroup. The relative high frequencies of two haplogroups, E3b2 (35.1%) and J (30%) was confirmed in Tunisia. We reported in the present study and for the first time, that J1J* haplogroup may confer a risk factor for infertility in the Tunisian population and we suggested that R1 haplogroup may ensure certain stability to Y-chromosome in Tunisian men.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10517714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the risk of paternal cell contamination in PGT and the necessity of intracytoplasmic sperm injection. PGT中父系细胞污染风险的调查及卵浆内单精子注射的必要性。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2022-05-10 DOI: 10.1080/14647273.2022.2026498

Colleen Lynch, Ellen Armstrong, Marina Charitou, Tony Gordon, Darren Griffin

引用次数: 0

EMLA (lidocaine-prilocaine) cream for pain relief during hysterosalpingography: a systematic review and meta-analysis of randomised placebo-controlled trials. EMLA(利多卡因-丙胺卡因)乳膏用于子宫输卵管造影期间疼痛缓解:随机安慰剂对照试验的系统回顾和荟萃分析。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2022-02-27 DOI: 10.1080/14647273.2022.2040748

Ahmed Abu-Zaid, Saeed Baradwan, Mohammed Abuzaid, Rayan AlSghan, Osama Alomar, Hany Salem, Ismail A Al-Badawi

{"title":"EMLA (lidocaine-prilocaine) cream for pain relief during hysterosalpingography: a systematic review and meta-analysis of randomised placebo-controlled trials.","authors":"Ahmed Abu-Zaid, Saeed Baradwan, Mohammed Abuzaid, Rayan AlSghan, Osama Alomar, Hany Salem, Ismail A Al-Badawi","doi":"10.1080/14647273.2022.2040748","DOIUrl":"10.1080/14647273.2022.2040748","url":null,"abstract":"We systematically investigated the efficacy and safety of EMLA (5% lidocaine-prilocaine cream) versus placebo for pain relief among infertile patients undergoing hysterosalpingography (HSG). We screened four databases from inception until 25 November 2020. We included only randomised placebo-controlled trials (RCTs) and assessed their risk of bias. The main efficacy outcomes included safety and pain scores during the different stages of HSG. The pooled outcomes were summarised as mean difference (MD) with 95% confidence interval (CI). Three RCTs were included, comprising 258 patients (131 and 127 patients received EMLA and placebo, respectively). All RCTs revealed an overall low risk of bias. EMLA significantly reduced pain perception during cervical instrumentation of tenaculum and cannula (MD = -1.53, 95% CI [-2.59, -0.47], p = 0.005) and at 24 h after completion of HSG (MD = -1.30, 95% CI [-2.57, -0.03], p = 0.04). Despite EMLA decreased pain perception during the other procedural stages of HSG, the differences were not statistically significant compared with placebo. EMLA was safe and free of local and systemic adverse reactions. This meta-analysis advocates that topical application of 5% EMLA cream is safe and correlates with decreased pain perception during HSG, particularly during the cervical instrumentation step and at 24 h after HSG completion.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44719676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The role of CFTR channel in female infertility. CFTR 通道在女性不孕症中的作用。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2022-12-28 DOI: 10.1080/14647273.2022.2161427

Mahmoud M Habibullah

引用次数: 1

FSH administration at 12-hour intervals for the first 2 days, combined with mandatory GnRH-agonist trigger and blastocyst vitrification in women (<80Kg) with high AMH levels, results in higher cumulative live birth rates and is safer. 对 AMH 水平较高的女性（体重小于 80 千克），在最初 2 天内每隔 12 小时给予 FSH，同时强制使用 GnRH 激动剂触发和囊胚玻璃化，可获得更高的累积活产率，而且更安全。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2023-01-16 DOI: 10.1080/14647273.2023.2164870

Richard Fleming, Mariano Mascarenhas, Frances Roebuck, Patricia Ambrose, Clare Noble, Ann Henderson, Nicole Gibson, Marco Gaudoin

{"title":"FSH administration at 12-hour intervals for the first 2 days, combined with mandatory GnRH-agonist trigger and blastocyst vitrification in women (<80Kg) with high AMH levels, results in higher cumulative live birth rates and is safer.","authors":"Richard Fleming, Mariano Mascarenhas, Frances Roebuck, Patricia Ambrose, Clare Noble, Ann Henderson, Nicole Gibson, Marco Gaudoin","doi":"10.1080/14647273.2023.2164870","DOIUrl":"10.1080/14647273.2023.2164870","url":null,"abstract":"We aimed to determine if a programme change to 12 hourly injections of FSH (150 IU per injection) for the first 2 days of stimulation in women with high ovarian reserve (AMH ≥ 30 pmol/L), followed by 24 hourly injections, would elicit increased earlier follicular recruitment, higher egg yields and blastocyst embryos for cryopreservation, leading to potential higher cumulative pregnancy rates, than conventional daily injections throughout. For safety reasons, the approach required mandatory cryopreservation of all blastocysts (mFET group; n = 74), after ovulation trigger with GnRH-agonist, in GnRH-antagonist controlled cycles. The 'Comparator group' (n = 91) comprised women with the same high AMH levels treated with the same base dose of FSH, with the aim of fresh blastocyst transfer and cryopreservation of supernumerary embryos, treated over the preceding 2 years. There was no difference in age, AMH, weight or BMI between the groups. The mFET group achieved higher egg (17.7 versus 11.7; p < 0.001) and embryo (10.9 versus 7.2; p < 0.001) yields and fewer cases with sub-optimal embryo yields (7% versus 22%; p = 0.018). The cumulative live birth rate was superior in the mFET group (73% versus 43%), as was the safety profile, and negligible rate of treatment plan modification.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10531843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impacts of the COVID-19 pandemic on early pregnancy outcomes among women undergoing frozen-thawed embryo transfer: a retrospective cohort study. COVID-19 大流行对接受冷冻解冻胚胎移植的妇女早孕结果的影响：一项回顾性队列研究。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2023-09-05 DOI: 10.1080/14647273.2023.2251680

Xin Li, Xiaodie Yao, Lijing Bai, Renjie Lu, Shijie Geng, Xiufeng Ling, Juan Wen, Lingmin Hu

{"title":"Impacts of the COVID-19 pandemic on early pregnancy outcomes among women undergoing frozen-thawed embryo transfer: a retrospective cohort study.","authors":"Xin Li, Xiaodie Yao, Lijing Bai, Renjie Lu, Shijie Geng, Xiufeng Ling, Juan Wen, Lingmin Hu","doi":"10.1080/14647273.2023.2251680","DOIUrl":"10.1080/14647273.2023.2251680","url":null,"abstract":"The effect of COVID-19 pandemic on early pregnancy outcomes among women undergoing frozen-thawed embryo transfer (FET) remains unclear. We aimed to evaluate whether early pregnancy outcomes were altered in patients undergoing FET during the pandemic. In this retrospective cohort study, women conceived through FET in 2016-2021 from two hospitals in China were included. The early pregnancy outcomes were compared using Logistic regression model, including biochemical pregnancy rate (BPR), clinical pregnancy rate (CPR), and early pregnancy loss rate (EPLR). A total of 16,669 (67.2%) and 6,113 (26.8%) FET cycles enrolled before and during the pandemic, respectively. Univariate analyses showed that women undergoing FET during the pandemic had significantly increased BPR (72.9% vs. 69.7%) and CPR (59.5% vs. 55.0%), and significantly decreased EPLR (13.7% vs. 16.7%) compared to pre-pandemic (all P < 0.001). Moreover, after adjustment, the results were in accordance with univariate analysis for CPR [adjusted OR (95%CI) = 1.08 (1.01-1.14)] and EPLR [adjusted OR (95%CI) = 0.82 (0.73-0.91)], while the statistical significance between BPR and the pandemic disappeared. In summary, women conceived by FET did not have a reduced possibility of clinical pregnancy and a higher risk of early pregnancy loss during the pandemic compared with the pre-pandemic.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10153969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Longitudinal trends in fertility in women of advanced maternal age in the United States and Sweden from 1935-2018 and comparison to maternal mortality ratios. 1935-2018 年美国和瑞典高龄产妇生育率的纵向趋势以及与孕产妇死亡率的比较。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2023-02-20 DOI: 10.1080/14647273.2022.2161075

Jessica Grubman, Marcelle Cedars, Nadia Diamond-Smith

{"title":"Longitudinal trends in fertility in women of advanced maternal age in the United States and Sweden from 1935-2018 and comparison to maternal mortality ratios.","authors":"Jessica Grubman, Marcelle Cedars, Nadia Diamond-Smith","doi":"10.1080/14647273.2022.2161075","DOIUrl":"10.1080/14647273.2022.2161075","url":null,"abstract":"Advanced maternal age (AMA, >35 years at delivery) confers maternal and foetal risks, particularly with age >45 years and nulliparity, but longitudinal comparative data on age- and parity-specific AMA fertility is lacking. We used the Human Fertility Database (HFD), a publicly available, international database, to analyse fertility in US and Swedish women aged 35-54 from 1935 to 2018. Age-specific fertility rates (ASFR), total birth counts, and proportion of AMA births were evaluated across maternal age, parity, and time, and compared to maternal mortality rates during the same time. In the US, total AMA births nadired in the 1970s, and have risen since. Until 1980, most AMA births were to women completing parity 5 or higher; since then, most have been to low parity women. While ASFR in 35 to 39 year olds was highest in 2015, ASFR in women 40-44 and 45-49 were highest in 1935, though they have been rising recently, especially in low-parity women. While the same AMA fertility trends were seen in the US and Sweden from 1970-2018, maternal mortality rates have risen in the US despite remaining low in Sweden. Although AMA is known to contribute to maternal mortality, this discrepancy merits further consideration.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10757877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Human ovarian cryopreservation: vitrification versus slow freezing from histology to gene expression. 人类卵巢冷冻保存：从组织学到基因表达的玻璃化与缓慢冷冻。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2022-11-17 DOI: 10.1080/14647273.2022.2136540

Pauline Jaeger, Cyrielle Fournier, Claire Santamaria, Eloise Fraison, Nicolas Morel-Journel, Mehdi Benchaib, Bruno Salle, Jacqueline Lornage, Elsa Labrune

{"title":"Human ovarian cryopreservation: vitrification versus slow freezing from histology to gene expression.","authors":"Pauline Jaeger, Cyrielle Fournier, Claire Santamaria, Eloise Fraison, Nicolas Morel-Journel, Mehdi Benchaib, Bruno Salle, Jacqueline Lornage, Elsa Labrune","doi":"10.1080/14647273.2022.2136540","DOIUrl":"10.1080/14647273.2022.2136540","url":null,"abstract":"Cryopreservation of ovarian tissue is one of the strategies offered to girls and women needing gonadotoxic treatment to preserve their fertility. The reference method to cryopreserve is slow freezing; vitrification is an alternative method. The aim was to evaluate which of the two is the best method for human ovarian tissue cryopreservation. Each ovary was divided into three groups: (i) fresh; (ii) slow freezing; and (iii) vitrification. An evaluation of the follicular density, quality and the expression six genes (CYP11A, STAR, GDF9, ZP3, CDK2, CDKN1A) were performed. We observed no significant difference in follicular density within these three groups. Slow freezing altered the primordial follicles compared to the fresh tissue (31.8% vs 55.9%, p = 0.046). The expression of genes involved in steroidogenesis varied after cryopreservation compared to the fresh group; CYP11A was under-expressed in slow freezing group (p = 0.01), STAR was under-expressed in the vitrification group (p = 0.01). Regarding the expression of genes involved in cell cycle regulation, CDKN1A was significantly under-expressed in both freezing groups (slow freezing: p = 0.0008; vitrification: p = 0.03). Vitrification had no effect on the histological quality of the follicles at any stage of development compared to fresh tissue. There was no significant difference in gene expression between the two techniques.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40469575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0