Human Fertility最新文献_第10页

Psychological distress in infertile women: the role of quality of marital relationships and self-compassion. 不孕妇女的心理困扰：婚姻关系质量和自我同情的作用。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2023-06-24 DOI: 10.1080/14647273.2023.2222547

Mehrdad Hajihasani, Raziyeh Ekhtiari Amiri

{"title":"Psychological distress in infertile women: the role of quality of marital relationships and self-compassion.","authors":"Mehrdad Hajihasani, Raziyeh Ekhtiari Amiri","doi":"10.1080/14647273.2023.2222547","DOIUrl":"10.1080/14647273.2023.2222547","url":null,"abstract":"Infertility is a common disease. At least 10-15% of women deal with infertility in some way. Infertile women suffer from a higher degree of psychological distress compared to fertile women. This study aims to identify the role of the quality of marital relationships and self-compassion in psychological distress in infertile women. The participants were 400 women who were referred to fertility clinics in Iran over a two-year period. Questionnaires containing Demographic Questionnaire, Psychological Distress Scale (DASS), Marital Quality Scale (MQS) and Self-Compassion Scale (MCS). The results showed that predictor variables explain a total of 29.9% of the variance of psychological distress in infertile women. The quality of marital relationships (p = 0.001 and β = -0.49) and self-compassion (p < 0.05 and β = -0.08) can negatively predict the psychological distress of infertile women. Considering that the significant role of the quality of marital relationships and self-compassion in the psychological distress of infertile women has been confirmed; therefore, interventions that focus on the quality of marital relationships and self-compassion may be effective and should be used as a resource to combat psychological distress in infertile women.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":" ","pages":"1393-1399"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10053456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Y-chromosome haplogroups and Azoospermia Factor (AZF) analysis in Tunisian infertile male. 突尼斯不育男性的 Y 染色体单倍群和无精子症因子（AZF）分析。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2023-01-02 DOI: 10.1080/14647273.2022.2163194

Myriam Ghorbel, Siwar Baklouti-Gargouri, Rim Keskes, Afifa Sellami, Ken McElreavy, Leila Ammar-Keskes

{"title":"Y-chromosome haplogroups and Azoospermia Factor (AZF) analysis in Tunisian infertile male.","authors":"Myriam Ghorbel, Siwar Baklouti-Gargouri, Rim Keskes, Afifa Sellami, Ken McElreavy, Leila Ammar-Keskes","doi":"10.1080/14647273.2022.2163194","DOIUrl":"10.1080/14647273.2022.2163194","url":null,"abstract":"The aim of the present study was to clarify the implication of Y chromosome genetic variations and haplogroups in Tunisian infertile men. A total of 27 Y-chromosomal binary markers partial microdeletions (gr/gr, b1/b3 and b2/b3) and copy number variation of DAZ and CDY genes in the AZFc region were analysed in 131 Tunisian infertile men with spermatogenic failure and severe reduced sperm concentrations and in 85 normospermic men as controls. Eleven different haplogroups in the overall population study (E3b2; J1J*, E1, E3b*, F, G, K, P/Q, R*, R1* and R1a1) were found. Interestingly, the J1J* haplogroup was significantly more frequent in azoo/oligospermic patients than in normospermic men (35.1% and 22.3%, respectively (p value = 0.04)). Results showed also that patients without DAZ/CDY1 copies loss and without partial microdeletions belonged to the R1 haplogroup. The relative high frequencies of two haplogroups, E3b2 (35.1%) and J (30%) was confirmed in Tunisia. We reported in the present study and for the first time, that J1J* haplogroup may confer a risk factor for infertility in the Tunisian population and we suggested that R1 haplogroup may ensure certain stability to Y-chromosome in Tunisian men.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":" ","pages":"1238-1247"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10517714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimising the screening for haemoglobinopathies in pregnancy planning. 优化怀孕计划中的血红蛋白病筛查。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2023-03-21 DOI: 10.1080/14647273.2023.2190041

Robert S Nickel, Deepika S Darbari, Brenda Martin, Lisa Thaniel, Harvey Stern, Cyril Jacquot

{"title":"Optimising the screening for haemoglobinopathies in pregnancy planning.","authors":"Robert S Nickel, Deepika S Darbari, Brenda Martin, Lisa Thaniel, Harvey Stern, Cyril Jacquot","doi":"10.1080/14647273.2023.2190041","DOIUrl":"10.1080/14647273.2023.2190041","url":null,"abstract":"Haemoglobinopathies are among the most common inherited disorders around the world. In the United States the diagnosis of haemoglobinopathy or a carrier state is made by universal newborn screening. However, many individuals of childbearing age do not know they are a haemoglobinopathy carrier. Screening for common haemoglobinopathies is generally offered as a part of pregnancy planning so that prospective parents can be counselled regarding the risk of having a child with a haemoglobinopathy. Multiple tests exist to screen patients for presence of haemoglobinopathy carrier or disease state; however, it is crucial to order and interpret the results correctly to appropriately counsel couples. In this case series, we describe clinical scenarios where prospective parents were surprised to unexpectedly have a child with sickle cell disease, a haemoglobinopathy that causes severe clinical complications. Through these cases we demonstrate that deficiencies in testing can occur at different levels which may lead to incorrect estimation of the risk of having a child affected by a haemoglobinopathy. Consultation with a haematologist, laboratory medicine specialist, or genetic counsellor should be considered to select the appropriate test and interpret its results.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":" ","pages":"1334-1339"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9516069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of delayed blastulation and expansion grade on clinical outcomes of high-quality blastocyst transfer: an analysis of 1751 frozen-thawed cycles. 囊胚移植延迟和扩增等级对优质囊胚移植临床结果的影响：对 1751 个冷冻解冻周期的分析。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2023-03-21 DOI: 10.1080/14647273.2023.2188491

Yingchun Guo, Yuting Xiang, Yanfang Wang, Tingting Li, Cong Fang

{"title":"Influence of delayed blastulation and expansion grade on clinical outcomes of high-quality blastocyst transfer: an analysis of 1751 frozen-thawed cycles.","authors":"Yingchun Guo, Yuting Xiang, Yanfang Wang, Tingting Li, Cong Fang","doi":"10.1080/14647273.2023.2188491","DOIUrl":"10.1080/14647273.2023.2188491","url":null,"abstract":"The aim of the study was to compare retrospectively the extent of blastulation timing (Day 5 or later) and expansion grade to predict the ability of blastocysts to give rise to a pregnancy. Blastocysts frozen on day 5 with a lower expansion grade (group D5) or day 6 with a higher expansion grade (group D6) were included. A single embryo was thawed and transferred on day 5 after ovulation or progesterone supplementation. Differences in patient baseline characteristics, endometrial preparation and pregnancy outcomes between groups were stratified by patient age and anti-Müllerian hormone (AMH) levels. Logistic regression was used to analyse the results. A total of 617 blastocysts in group D5 and 1134 blastocysts in group D6 were assessed. Stratified analyses showed higher biochemical pregnancy, clinical pregnancy and live birth rates for patients aged less than 30 years old, and higher ongoing pregnancy rate for patients with AMH ≥ 1.1 ng/ml. For patients aged less than 30 years old, the biochemical pregnancy, clinical pregnancy and live birth rates in group D5 were higher than those in group D6.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":" ","pages":"1313-1321"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9145079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Longitudinal trends in fertility in women of advanced maternal age in the United States and Sweden from 1935-2018 and comparison to maternal mortality ratios. 1935-2018 年美国和瑞典高龄产妇生育率的纵向趋势以及与孕产妇死亡率的比较。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2023-02-20 DOI: 10.1080/14647273.2022.2161075

Jessica Grubman, Marcelle Cedars, Nadia Diamond-Smith

{"title":"Longitudinal trends in fertility in women of advanced maternal age in the United States and Sweden from 1935-2018 and comparison to maternal mortality ratios.","authors":"Jessica Grubman, Marcelle Cedars, Nadia Diamond-Smith","doi":"10.1080/14647273.2022.2161075","DOIUrl":"10.1080/14647273.2022.2161075","url":null,"abstract":"Advanced maternal age (AMA, >35 years at delivery) confers maternal and foetal risks, particularly with age >45 years and nulliparity, but longitudinal comparative data on age- and parity-specific AMA fertility is lacking. We used the Human Fertility Database (HFD), a publicly available, international database, to analyse fertility in US and Swedish women aged 35-54 from 1935 to 2018. Age-specific fertility rates (ASFR), total birth counts, and proportion of AMA births were evaluated across maternal age, parity, and time, and compared to maternal mortality rates during the same time. In the US, total AMA births nadired in the 1970s, and have risen since. Until 1980, most AMA births were to women completing parity 5 or higher; since then, most have been to low parity women. While ASFR in 35 to 39 year olds was highest in 2015, ASFR in women 40-44 and 45-49 were highest in 1935, though they have been rising recently, especially in low-parity women. While the same AMA fertility trends were seen in the US and Sweden from 1970-2018, maternal mortality rates have risen in the US despite remaining low in Sweden. Although AMA is known to contribute to maternal mortality, this discrepancy merits further consideration.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":" ","pages":"1219-1227"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10757877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impacts of the COVID-19 pandemic on early pregnancy outcomes among women undergoing frozen-thawed embryo transfer: a retrospective cohort study. COVID-19 大流行对接受冷冻解冻胚胎移植的妇女早孕结果的影响：一项回顾性队列研究。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2023-09-05 DOI: 10.1080/14647273.2023.2251680

Xin Li, Xiaodie Yao, Lijing Bai, Renjie Lu, Shijie Geng, Xiufeng Ling, Juan Wen, Lingmin Hu

{"title":"Impacts of the COVID-19 pandemic on early pregnancy outcomes among women undergoing frozen-thawed embryo transfer: a retrospective cohort study.","authors":"Xin Li, Xiaodie Yao, Lijing Bai, Renjie Lu, Shijie Geng, Xiufeng Ling, Juan Wen, Lingmin Hu","doi":"10.1080/14647273.2023.2251680","DOIUrl":"10.1080/14647273.2023.2251680","url":null,"abstract":"The effect of COVID-19 pandemic on early pregnancy outcomes among women undergoing frozen-thawed embryo transfer (FET) remains unclear. We aimed to evaluate whether early pregnancy outcomes were altered in patients undergoing FET during the pandemic. In this retrospective cohort study, women conceived through FET in 2016-2021 from two hospitals in China were included. The early pregnancy outcomes were compared using Logistic regression model, including biochemical pregnancy rate (BPR), clinical pregnancy rate (CPR), and early pregnancy loss rate (EPLR). A total of 16,669 (67.2%) and 6,113 (26.8%) FET cycles enrolled before and during the pandemic, respectively. Univariate analyses showed that women undergoing FET during the pandemic had significantly increased BPR (72.9% vs. 69.7%) and CPR (59.5% vs. 55.0%), and significantly decreased EPLR (13.7% vs. 16.7%) compared to pre-pandemic (all P < 0.001). Moreover, after adjustment, the results were in accordance with univariate analysis for CPR [adjusted OR (95%CI) = 1.08 (1.01-1.14)] and EPLR [adjusted OR (95%CI) = 0.82 (0.73-0.91)], while the statistical significance between BPR and the pandemic disappeared. In summary, women conceived by FET did not have a reduced possibility of clinical pregnancy and a higher risk of early pregnancy loss during the pandemic compared with the pre-pandemic.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":" ","pages":"1477-1484"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10153969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of CFTR channel in female infertility. CFTR 通道在女性不孕症中的作用。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2022-12-28 DOI: 10.1080/14647273.2022.2161427

Mahmoud M Habibullah

引用次数: 1

Sperm toxicity testing on lubricant gels: should we be recommending 'fertility-friendly' specialist products? 润滑剂凝胶的精子毒性测试:我们应该推荐“生育友好”的专业产品吗?

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2022-04-04 DOI: 10.1080/14647273.2022.2053214

Joseph Tomlinson, Karen Pooley, Mathew Tomlinson

{"title":"Sperm toxicity testing on lubricant gels: should we be recommending 'fertility-friendly' specialist products?","authors":"Joseph Tomlinson, Karen Pooley, Mathew Tomlinson","doi":"10.1080/14647273.2022.2053214","DOIUrl":"10.1080/14647273.2022.2053214","url":null,"abstract":"Couples trying to conceive or providing samples for Assisted Reproductive Technologies (ART) are advised against the use of lubricant-gels due to the risk of sperm-toxicity. However, gels now exist which are specifically formulated to help couples conceive but without consensus on their toxicity relative to non-specialist products. This study tested gels recently introduced as 'sperm friendly' (FertilSafe Plus, Fertile Check) alongside established lubricants intended for pleasure only using a recently published toxicity testing regime. Computer Assisted Sperm Analysis (CASA) was performed at 1 and 2 h on donor sperm (n = 12) pre-incubated with each gel (10% v/v) and controls. All gels led to a significant loss of motility/velocity at 1 and 2 h (p < 0.01), with the most significant loss from the 2 Durex pleasure products (11% and 15%, vs 47% progression) at 60 min, although these performed better than saliva (used as negative control). Incubation with FertilSafePlus led to the smallest loss of motility (24% vs 47%) at 1 h. Saliva and products designed for lubrication only exhibited the most negative effect on motility and those marketed as 'sperm safe' could be considered the best performers. Whether these affects are due to direct toxicity or are indirect due to other factors such as viscosity, pH or osmolality remains uncertain.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"1 1","pages":"1028-1031"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45099390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FSH administration at 12-hour intervals for the first 2 days, combined with mandatory GnRH-agonist trigger and blastocyst vitrification in women (<80Kg) with high AMH levels, results in higher cumulative live birth rates and is safer. 对 AMH 水平较高的女性（体重小于 80 千克），在最初 2 天内每隔 12 小时给予 FSH，同时强制使用 GnRH 激动剂触发和囊胚玻璃化，可获得更高的累积活产率，而且更安全。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2023-01-16 DOI: 10.1080/14647273.2023.2164870

Richard Fleming, Mariano Mascarenhas, Frances Roebuck, Patricia Ambrose, Clare Noble, Ann Henderson, Nicole Gibson, Marco Gaudoin

{"title":"FSH administration at 12-hour intervals for the first 2 days, combined with mandatory GnRH-agonist trigger and blastocyst vitrification in women (<80Kg) with high AMH levels, results in higher cumulative live birth rates and is safer.","authors":"Richard Fleming, Mariano Mascarenhas, Frances Roebuck, Patricia Ambrose, Clare Noble, Ann Henderson, Nicole Gibson, Marco Gaudoin","doi":"10.1080/14647273.2023.2164870","DOIUrl":"10.1080/14647273.2023.2164870","url":null,"abstract":"We aimed to determine if a programme change to 12 hourly injections of FSH (150 IU per injection) for the first 2 days of stimulation in women with high ovarian reserve (AMH ≥ 30 pmol/L), followed by 24 hourly injections, would elicit increased earlier follicular recruitment, higher egg yields and blastocyst embryos for cryopreservation, leading to potential higher cumulative pregnancy rates, than conventional daily injections throughout. For safety reasons, the approach required mandatory cryopreservation of all blastocysts (mFET group; n = 74), after ovulation trigger with GnRH-agonist, in GnRH-antagonist controlled cycles. The 'Comparator group' (n = 91) comprised women with the same high AMH levels treated with the same base dose of FSH, with the aim of fresh blastocyst transfer and cryopreservation of supernumerary embryos, treated over the preceding 2 years. There was no difference in age, AMH, weight or BMI between the groups. The mFET group achieved higher egg (17.7 versus 11.7; p < 0.001) and embryo (10.9 versus 7.2; p < 0.001) yields and fewer cases with sub-optimal embryo yields (7% versus 22%; p = 0.018). The cumulative live birth rate was superior in the mFET group (73% versus 43%), as was the safety profile, and negligible rate of treatment plan modification.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":" ","pages":"1271-1278"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10531843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

We want to feel valued: eggs donors' experiences of donation. 我们希望得到重视：卵子捐献者的捐赠经历。

IF 1.9 4区医学

Human Fertility Pub Date : 2023-12-01 Epub Date: 2023-01-10 DOI: 10.1080/14647273.2022.2164226

Sonja Goedeke, Heather Gamble, Rebecca Thurlow

{"title":"We want to feel valued: eggs donors' experiences of donation.","authors":"Sonja Goedeke, Heather Gamble, Rebecca Thurlow","doi":"10.1080/14647273.2022.2164226","DOIUrl":"10.1080/14647273.2022.2164226","url":null,"abstract":"Egg donation in New Zealand is identity-release, with donor-conceived individuals having the right to access donors' identifying information at the age of 18. It also allows donors and previously unknown recipients to meet prior to donation. Further, donation is altruistic, although reimbursement of costs is possible. In our previous paper we explored the motivations of 21 egg donors in this context and reported that they are motivated to donate as an act of personal gift-giving to recipients who may become known to them through donation, and that they do not want to be compensated for this financially. In this paper, drawing on in-depth interviews, we report on donors' experiences of the donation process and subsequent to donation. Donors understood their donations to be a significant act, both for the recipients and their families, but also for themselves, particularly given the multiple sacrifices which they willingly made. Donors wished for their gift and their role to be valued and acknowledged through being appreciated, informed, involved and supported by recipients and clinics before, during and after their donations. These findings have implications for clinical practice and care, offering insight into how best to support donors prior and subsequent to donation.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"26 2","pages":"326-336"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9783811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0