Human Fertility最新文献

Risk of adverse pregnancy outcomes after abnormal hysterosalpingography. 异常子宫输卵管造影后不良妊娠结局的风险。

IF 2.1 4区医学

Human Fertility Pub Date : 2025-12-01 Epub Date: 2025-01-13 DOI: 10.1080/14647273.2024.2431109

Erika Gandelsman, Leonti Grin, Tamar Wainstock, Roza Berkovitz Shperling, Elena Scherbina, Bozhena Saar-Ryss

{"title":"Risk of adverse pregnancy outcomes after abnormal hysterosalpingography.","authors":"Erika Gandelsman, Leonti Grin, Tamar Wainstock, Roza Berkovitz Shperling, Elena Scherbina, Bozhena Saar-Ryss","doi":"10.1080/14647273.2024.2431109","DOIUrl":"10.1080/14647273.2024.2431109","url":null,"abstract":"Objective: To investigate the association between an abnormal hysterosalpingogram (HSG) and obstetrical and neonatal outcomes.Design: A retrospective cohort study comparing outcomes between women with normal versus abnormal tubal patency and uterine cavity on HSG.Results: Among 2181 women included in the study, 494 (22.6%) had an abnormal HSG. Of these, 207 (42%) presented with uterine abnormalities, 336 (68%) with tubal abnormalities and 49 (10%) with both. The study identified 232 clinical pregnancies in the abnormal HSG group and 814 pregnancies in controls. Women with abnormal HSG showed higher rates of preterm labour (PTL) compared to controls (13.6% vs. 7.7%, p < 0.05, n = 1687). Multivariate analysis revealed that any HSG abnormality was associated with an increased risk of PTL (aOR 2.39, 1.04-5.51). When analysing by type of abnormality, uterine abnormalities increased the risk of preeclampsia (aOR 2.86, 1.06-7.7) and low birthweight (aOR 2.31, 1.0-5.35), while tubal abnormalities were specifically associated with increased risk of PTL (aOR 3.87, 1.63-9.19).Conclusion: An abnormal HSG study was associated with adverse obstetrical outcomes. Specifically, uterine abnormalities increased the risk of preeclampsia and birthweight below 10th percentile, while tubal abnormalities were associated with a heightened risk of PTL.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"28 1","pages":"2431109"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143055882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Women, Wombs and Warnock: 40 years after the Warnock Report, is legislation fit for purpose for uterus transplantation? 妇女，子宫和沃诺克：沃诺克报告40年后，立法是否适合子宫移植的目的？

IF 2.1 4区医学

Human Fertility Pub Date : 2025-12-01 Epub Date: 2025-04-15 DOI: 10.1080/14647273.2025.2492115

Natasha Hammond-Browning

{"title":"Women, Wombs and Warnock: 40 years after the Warnock Report, is legislation fit for purpose for uterus transplantation?","authors":"Natasha Hammond-Browning","doi":"10.1080/14647273.2025.2492115","DOIUrl":"https://doi.org/10.1080/14647273.2025.2492115","url":null,"abstract":"This article examines and evaluates the adequacy of current legislation regarding uterus transplants in light of the Warnock Committee's foundational work on reproductive ethics and technology. With increasing advancements in reproductive technology, the potential for uterus transplants to provide opportunities for cisgender women with absolute uterine factor infertility (AUFI) to gestate has garnered significant attention. However, existing legal frameworks often lag behind medical innovations, leading to disparities in access, regulation, and patient rights. Questions also arise regarding applying existing legislation to novel medical innovations, such as the potential to provide a uterus transplant to transgender women. As uterus transplantation emerges as a viable treatment option for cisgender women with absolute uterine factor infertility, the need for comprehensive legal frameworks becomes increasingly urgent and so this article assesses whether existing assisted reproduction laws are fit for purpose or whether reform is required given advances in reproductive medicine such as uterus transplantation.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"28 1","pages":"2492115"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144011523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expression of Concern: Comparison of macroscopic one-layer over number 1 nylon suture vasovasostomy with the standard two-layer microsurgical procedure. 关注表达：1号尼龙缝合血管造口术与标准两层显微外科手术的比较。

IF 2.1 4区医学

Human Fertility Pub Date : 2025-12-01 Epub Date: 2025-04-17 DOI: 10.1080/14647273.2025.2480402

引用次数: 0

Can a lack of knowledge of the ovulatory cycle result in primary infertility? Evidence from selected South Asian countries. 缺乏对排卵周期的了解会导致原发性不孕吗？来自选定南亚国家的证据。

IF 2.1 4区医学

Human Fertility Pub Date : 2025-12-01 Epub Date: 2024-12-19 DOI: 10.1080/14647273.2024.2441832

Pratyashee Ojah, Manas Ranjan Pradhan

{"title":"Can a lack of knowledge of the ovulatory cycle result in primary infertility? Evidence from selected South Asian countries.","authors":"Pratyashee Ojah, Manas Ranjan Pradhan","doi":"10.1080/14647273.2024.2441832","DOIUrl":"https://doi.org/10.1080/14647273.2024.2441832","url":null,"abstract":"Knowledge of ovulatory cycle (KOC) is a crucial factor for successful conception. Despite sizable number of women suffering from infertility, empirical evidence on the relation between infertility and KOC is rare in South Asia. This study assesses the association between primary infertility and KOC. The data of ever-married women aged 20-49 gathered in the recent rounds of Demographic and Health Survey (DHS) for India (2019-2021), Bangladesh (2017-2018), Pakistan (2017-2018) and Nepal (2022) were analyzed. Bivariate analysis and binary logistic regression were conducted through Stata (V.17) with a 5% significance level. Women with no KOC in India [AOR:1.71, C.I.: (1.54, 1.9)] and Bangladesh [AOR:2.6, C.I.: (1.67, 4.06)] had higher odds of primary infertility than their counterparts with correct KOC. The study concludes that correct KOC is a significant predictor of primary infertility in India and Bangladesh and is insignificant in Pakistan and Nepal. Moreover, higher age at marriage and no-visit to healthcare facility were the other significant predictors of primary infertility in all four countries. Women who are struggling to conceive would benefit from education related to the timing and identification of the fertile window, which may be provided through primary healthcare providers.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"28 1","pages":"2441832"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Increased paternal age adversely affects live birth rates in oocyte recipient cycles. 增加的父亲年龄对卵母细胞受体周期的活产率有不利影响。

IF 2.1 4区医学

Human Fertility Pub Date : 2025-12-01 Epub Date: 2025-05-23 DOI: 10.1080/14647273.2025.2506799

Yeliz Atik, Stavroula Kastora, Rawad Halimeh, Margot Zomer, Rabi Odia, Holly Exeter, Mina Vasilic, Suzanne Cawood, Wael Saab, Paul Serhal, Srividya Seshadri, Dimitrios Mavrelos, Ephia Yasmin

{"title":"Increased paternal age adversely affects live birth rates in oocyte recipient cycles.","authors":"Yeliz Atik, Stavroula Kastora, Rawad Halimeh, Margot Zomer, Rabi Odia, Holly Exeter, Mina Vasilic, Suzanne Cawood, Wael Saab, Paul Serhal, Srividya Seshadri, Dimitrios Mavrelos, Ephia Yasmin","doi":"10.1080/14647273.2025.2506799","DOIUrl":"https://doi.org/10.1080/14647273.2025.2506799","url":null,"abstract":"This retrospective cohort study was conducted in a single center to investigate the influence of paternal age on oocyte recipient cycles. 320 IVF/ICSI oocyte recipient cycles resulting in embryo transfers between 01/2015- 06/2022 and meeting the inclusion criteria: donors ≤35 years, endometrial thickness 6mm and normal endometrial cavity were analyzed. Donor or surgically retrieved sperm or PGT-A cycles were excluded. Paternal and recipient ages were grouped according to previous literature for comparability. Primary outcome was live birth rate, and secondary outcomes were clinical pregnancy and miscarriage rates. The median recipient, paternal and donor ages were 42 (IQR: 19-50), 43 (IQR: 38-46) and 26 years (IQR: 23-29). 55.6% [N=178] of the cycles were fresh and 44.3% [N=142] were frozen embryo transfers. Univariate and multivariate logistic regression, adjusted for semen WHO criteria, recipient age, IVF/ICSI and fresh/frozen cycles highlighted reduced odds of live birth by 79%, OR 0.21 [95%CI 0.11 to 0.38]; P<0.0001, clinical pregnancy by 58%, OR 0.42 [95%CI 0.31 to 0.89]; P<0.0001 and increased odds of miscarriage by 108%, OR 2.08 [95%CI 1.91 to 3.01]; P<0.0001 in those of paternal age 51 years compared to fathers ≤35 years. Our study identifies the negative impact of advanced paternal age.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"28 1","pages":"2506799"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Do very young oocyte donors negatively impact live birth rates in their recipients? 非常年轻的卵母细胞供体是否会对受者的活产率产生负面影响？

IF 2.1 4区医学

Human Fertility Pub Date : 2025-12-01 Epub Date: 2024-12-04 DOI: 10.1080/14647273.2024.2434524

Luisa Kahn, Sara Aziz, Benjamin Jones, Meen-Yau Thum, James Nicopoullos, Raef Faris, Srdjan Saso, Tim Bracewell-Milnes

{"title":"Do very young oocyte donors negatively impact live birth rates in their recipients?","authors":"Luisa Kahn, Sara Aziz, Benjamin Jones, Meen-Yau Thum, James Nicopoullos, Raef Faris, Srdjan Saso, Tim Bracewell-Milnes","doi":"10.1080/14647273.2024.2434524","DOIUrl":"https://doi.org/10.1080/14647273.2024.2434524","url":null,"abstract":"To understand whether there was an association between very young oocyte donors and adverse outcomes, this was a single centre retrospective study (Lister Fertility Clinic, London) examining data collected between 1st January 2010 and 31st December 2021. A total of 1,182 oocyte donors were included in the final analysis. Data was categorised by donor age in years; ≤22, 23-25, 26-28, 29-31, 32-34. Statistical analysis was performed using SPSS. Donors aged ≤22 years showed increased live birth rates (LBR) in fresh In Vitro Fertilisation (IVF) cycles when compared to donors aged 26-28 (p < 0.0136), 29-31 (p < 0.0044), and 32-34 (p < 0.0003) years, respectively. There was also an increased positive pregnancy rate in fresh IVF cycles for donor oocytes ≤22 years when compared to all other groups. The LBR and positive pregnancy rates decreased with increasing oocyte age with fresh IVF cycles. There was no significant difference in the LBR with frozen IVF cycles compared to fresh IVF cycles. Our data showed that very young oocyte donors are in fact associated with improved IVF outcomes, especially in fresh IVF cycles.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"28 1","pages":"2434524"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142768369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How do coping strategies influence fertility-related information seeking/avoidance? 应对策略如何影响生育相关信息的寻求/回避？

IF 2.1 4区医学

Human Fertility Pub Date : 2025-12-01 Epub Date: 2025-04-24 DOI: 10.1080/14647273.2025.2488759

Chloe May Smith, Mei Yee Tang, Gavin Clark, Suzanne Madgwick

{"title":"How do coping strategies influence fertility-related information seeking/avoidance?","authors":"Chloe May Smith, Mei Yee Tang, Gavin Clark, Suzanne Madgwick","doi":"10.1080/14647273.2025.2488759","DOIUrl":"https://doi.org/10.1080/14647273.2025.2488759","url":null,"abstract":"Despite the rise in discussions around fertility and reproductive health, recent evidence indicates that women's fertility awareness (FA) remains low, with many avoiding essential fertility-related information (FRI). Existing research has linked low awareness to demographic factors, yet psychological and behavioural determinants have received less attention. This study, therefore, explores the influence of coping strategies (avoidant and problem-focused) on FRI-seeking and avoidance behaviours and their effect on FA. A cross-sectional survey gathered data from 216 UK-based female participants aged 18-68 (M = 31.69, SD = 10.42), measuring demographics, FA, FRI-seeking and avoidance, and coping strategies. Data underwent multiple regression and moderation analyses. The average FA score was 17.87/29 (62%). FRI-seeking positively predicted FA (p < 0.001), while FRI-avoidance negatively predicted FA (p < 0.001). Avoidant coping significantly predicted increased FRI-avoidance (p < 0.001), moderating the relationship between FRI-avoidance and FA (p < 0.001). Problem-focused coping significantly predicted FRI-seeking (p < 0.001), moderating the relationship between FRI-seeking and FA (p < 0.001). Results suggest that coping strategies influence motivation to seek and avoid FRI. Future FRI and fertility education should be tailored to suit women's coping strategies to facilitate active engagement, which may enhance awareness and support more informed fertility decision-making.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"28 1","pages":"2488759"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mpox in assisted conception: should we be worried about this monkey wrench? 辅助受孕中的 Mpox：我们是否应该担心这个 "猴子扳手"？

IF 2.1 4区医学

Human Fertility Pub Date : 2025-12-01 Epub Date: 2024-12-16 DOI: 10.1080/14647273.2024.2441825

Michael B Yakass, Bryan J Woodward

引用次数: 0

Peer reviewers for Human Fertility in 2024. 2024年《人类生育》杂志的同行评审。

IF 2.1 4区医学

Human Fertility Pub Date : 2025-12-01 Epub Date: 2025-02-28 DOI: 10.1080/14647273.2025.2455862

引用次数: 0

Response to Kahana et al. (2024) Enhancing predictions of embryo implantation in thin endometrium: a comparative analysis of endometrial thickness in frozen versus fresh IVF cycles. 对Kahana等人（2024）加强薄子宫内膜胚胎着床的预测：冷冻与新鲜试管婴儿周期子宫内膜厚度的比较分析。

IF 2.1 4区医学