Risk of adverse pregnancy outcomes after abnormal hysterosalpingography.

IF 2.1 4区医学 Q2 OBSTETRICS & GYNECOLOGY

Human Fertility Pub Date : 2025-12-01 Epub Date: 2025-01-13 DOI:10.1080/14647273.2024.2431109

Erika Gandelsman, Leonti Grin, Tamar Wainstock, Roza Berkovitz Shperling, Elena Scherbina, Bozhena Saar-Ryss

{"title":"Risk of adverse pregnancy outcomes after abnormal hysterosalpingography.","authors":"Erika Gandelsman, Leonti Grin, Tamar Wainstock, Roza Berkovitz Shperling, Elena Scherbina, Bozhena Saar-Ryss","doi":"10.1080/14647273.2024.2431109","DOIUrl":null,"url":null,"abstract":"Objective: To investigate the association between an abnormal hysterosalpingogram (HSG) and obstetrical and neonatal outcomes.Design: A retrospective cohort study comparing outcomes between women with normal versus abnormal tubal patency and uterine cavity on HSG.Results: Among 2181 women included in the study, 494 (22.6%) had an abnormal HSG. Of these, 207 (42%) presented with uterine abnormalities, 336 (68%) with tubal abnormalities and 49 (10%) with both. The study identified 232 clinical pregnancies in the abnormal HSG group and 814 pregnancies in controls. Women with abnormal HSG showed higher rates of preterm labour (PTL) compared to controls (13.6% vs. 7.7%, p < 0.05, n = 1687). Multivariate analysis revealed that any HSG abnormality was associated with an increased risk of PTL (aOR 2.39, 1.04-5.51). When analysing by type of abnormality, uterine abnormalities increased the risk of preeclampsia (aOR 2.86, 1.06-7.7) and low birthweight (aOR 2.31, 1.0-5.35), while tubal abnormalities were specifically associated with increased risk of PTL (aOR 3.87, 1.63-9.19).Conclusion: An abnormal HSG study was associated with adverse obstetrical outcomes. Specifically, uterine abnormalities increased the risk of preeclampsia and birthweight below 10th percentile, while tubal abnormalities were associated with a heightened risk of PTL.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"28 1","pages":"2431109"},"PeriodicalIF":2.1000,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Human Fertility","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/14647273.2024.2431109","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/13 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: To investigate the association between an abnormal hysterosalpingogram (HSG) and obstetrical and neonatal outcomes.

Design: A retrospective cohort study comparing outcomes between women with normal versus abnormal tubal patency and uterine cavity on HSG.

Results: Among 2181 women included in the study, 494 (22.6%) had an abnormal HSG. Of these, 207 (42%) presented with uterine abnormalities, 336 (68%) with tubal abnormalities and 49 (10%) with both. The study identified 232 clinical pregnancies in the abnormal HSG group and 814 pregnancies in controls. Women with abnormal HSG showed higher rates of preterm labour (PTL) compared to controls (13.6% vs. 7.7%, p < 0.05, n = 1687). Multivariate analysis revealed that any HSG abnormality was associated with an increased risk of PTL (aOR 2.39, 1.04-5.51). When analysing by type of abnormality, uterine abnormalities increased the risk of preeclampsia (aOR 2.86, 1.06-7.7) and low birthweight (aOR 2.31, 1.0-5.35), while tubal abnormalities were specifically associated with increased risk of PTL (aOR 3.87, 1.63-9.19).

Conclusion: An abnormal HSG study was associated with adverse obstetrical outcomes. Specifically, uterine abnormalities increased the risk of preeclampsia and birthweight below 10th percentile, while tubal abnormalities were associated with a heightened risk of PTL.

查看原文本刊更多论文

目的：探讨子宫输卵管造影（HSG）异常与产科和新生儿预后之间的关系：调查子宫输卵管造影（HSG）异常与产科和新生儿预后之间的关系：一项回顾性队列研究，比较输卵管通畅性和子宫腔在 HSG 检查中正常与异常妇女的预后：在参与研究的 2181 名妇女中，有 494 名（22.6%）HSG 检查结果异常。其中，207 人（42%）子宫异常，336 人（68%）输卵管异常，49 人（10%）两者均有异常。研究在 HSG 异常组中发现了 232 例临床妊娠，在对照组中发现了 814 例妊娠。与对照组相比，HSG异常妇女的早产率（PTL）较高（13.6% 对 7.7%，P n = 1687）。多变量分析显示，任何 HSG 异常都与 PTL 风险增加有关（aOR 2.39，1.04-5.51）。根据异常类型进行分析，子宫异常会增加子痫前期（aOR 2.86，1.06-7.7）和低出生体重（aOR 2.31，1.0-5.35）的风险，而输卵管异常与 PTL 风险增加特别相关（aOR 3.87，1.63-9.19）：结论：HSG检查异常与不良产科结果有关。结论：HSG 检查异常与不良产科结果有关，特别是子宫异常会增加子痫前期和出生体重低于 10 百分位数的风险，而输卵管异常则会增加 PTL 的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Human Fertility OBSTETRICS & GYNECOLOGY-REPRODUCTIVE BIOLOGY

CiteScore

3.30

自引率

5.30%

发文量

期刊介绍： Human Fertility is a leading international, multidisciplinary journal dedicated to furthering research and promoting good practice in the areas of human fertility and infertility. Topics included span the range from molecular medicine to healthcare delivery, and contributions are welcomed from professionals and academics from the spectrum of disciplines concerned with human fertility. It is published on behalf of the British Fertility Society. The journal also provides a forum for the publication of peer-reviewed articles arising out of the activities of the Association of Biomedical Andrologists, the Association of Clinical Embryologists, the Association of Irish Clinical Embryologists, the British Andrology Society, the British Infertility Counselling Association, the Irish Fertility Society and the Royal College of Nursing Fertility Nurses Group. All submissions are welcome. Articles considered include original papers, reviews, policy statements, commentaries, debates, correspondence, and reports of sessions at meetings. The journal also publishes refereed abstracts from the meetings of the constituent organizations.