Human Fertility最新文献_第3页

Young adult's views on using a poster to learn about fertility: redesigning the fertility education poster. 年轻人对使用海报了解生育知识的看法：重新设计生育教育海报。

IF 1.9 4区医学

Human Fertility Pub Date : 2024-12-01 Epub Date: 2024-05-28 DOI: 10.1080/14647273.2024.2345675

Katie Hamilton, Joyce C Harper

{"title":"Young adult's views on using a poster to learn about fertility: redesigning the fertility education poster.","authors":"Katie Hamilton, Joyce C Harper","doi":"10.1080/14647273.2024.2345675","DOIUrl":"https://doi.org/10.1080/14647273.2024.2345675","url":null,"abstract":"Fertility awareness should be taught to everyone. The International Reproductive Health Education Collaboration (IRHEC) designed a fertility poster in 2019 but did not have a specific target group in mind. Studies have been conducted in Denmark and Sweden to determine how the poster can be redesigned. In this study, we carried out focus groups with young adults in the UK to ask their views of the poster, with the aim of redesigning it. Six focus groups were undertaken with twenty seven, 18-25 year olds. Five questions were asked: 1. What are your thoughts, feelings, and reactions to the poster? 2. Did you learn anything from the poster? 3. How has reading the poster impacted your opinions or thoughts about having children? 4. What are your opinions about using a poster format to inform and start reflections regarding family building? 5. Reading through each point are there any changes to be made? Content analysis was performed. Themes identified revealed the information on the poster gave the participants some anxiety and apprehension, especially regarding the effect of age on fertility, perceptions of IVF, and gaps in knowledge. The fertility education poster is a good resource for education, but other resources should be developed.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"27 1","pages":"2345675"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141158289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Best practice recommendations for medically assisted reproduction in patients with known cardiovascular disease or at high risk of cardiovascular disease. 对已知患有心血管疾病或心血管疾病高风险患者进行医学辅助生殖的最佳实践建议。

IF 1.9 4区医学

Human Fertility Pub Date : 2024-12-01 Epub Date: 2024-01-09 DOI: 10.1080/14647273.2023.2278295

Kate English, Charlotte Frise, Johanna Trinder, Matthew Cauldwell, Maggie Simpson, Dawn Adamson, Chris Elton, Gwenda Burns, Meenakshi Choudhary, Mike Nathanson, Leema Robert, Jim Moore, Pat O'Brien, Jyotsna Pundir

引用次数: 0

Evidence based management of patients with endometriosis undergoing assisted conception: British fertility society policy and practice recommendations. 辅助受孕子宫内膜异位症患者的循证管理：英国生育协会政策与实践建议。

IF 1.9 4区医学

Human Fertility Pub Date : 2024-12-01 Epub Date: 2024-01-16 DOI: 10.1080/14647273.2023.2288634

Karolina Skorupskaite, Madeleine Hardy, Harish Bhandari, Ephia Yasmin, Wael Saab, Srividya Seshadri

{"title":"Evidence based management of patients with endometriosis undergoing assisted conception: British fertility society policy and practice recommendations.","authors":"Karolina Skorupskaite, Madeleine Hardy, Harish Bhandari, Ephia Yasmin, Wael Saab, Srividya Seshadri","doi":"10.1080/14647273.2023.2288634","DOIUrl":"10.1080/14647273.2023.2288634","url":null,"abstract":"Endometriosis is a chronic inflammatory condition in women of reproductive age, which can lead to infertility and pelvic pain. Endometriosis associated infertility is multifactorial in nature adversely affecting each step of the natural reproductive physiology and thereby processes and outcomes of Assisted Reproductive Technology (ART) cycles. These outcomes are further complicated by the subtype of endometriosis, being peritoneal, deep infiltrating and ovarian, which bear negative effects on ovarian reserve, response to stimulation, accessibility for oocyte retrieval, intraoperative safety and endometrial receptivity. There is still a lack of clear guidance about the role of surgery for ovarian endometriosis/endometriomas. This guideline evaluates the evidence of the impact of pelvic endometriosis and endometriomas on the outcome of ART and provides recommendations for management options before and during ART including intra-uterine insemination. Recommendations are made based on the current evidence for the management of patients with endometriosis across each step of ART with the primary aim of improving ART outcomes.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"27 1","pages":"2288634"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139472192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A systematic review of interventions to improve male knowledge of fertility and fertility-related risk factors. 对提高男性生育知识和生育相关风险因素的干预措施进行系统性审查。

IF 1.9 4区医学

Human Fertility Pub Date : 2024-12-01 Epub Date: 2024-03-18 DOI: 10.1080/14647273.2024.2328066

Srinithy Krishnan, Michael P Daly, Ruth Kipping, China Harrison

{"title":"A systematic review of interventions to improve male knowledge of fertility and fertility-related risk factors.","authors":"Srinithy Krishnan, Michael P Daly, Ruth Kipping, China Harrison","doi":"10.1080/14647273.2024.2328066","DOIUrl":"10.1080/14647273.2024.2328066","url":null,"abstract":"Male infertility is a global health concern. The effectiveness of interventions developed to improve males' knowledge of fertility regulation and fertility-related risk factors remains unclear. This systematic review aimed to synthesize and evaluate the evidence for these interventions. Four databases were searched from inception to June 2023. Eligible studies examined interventions to increase fertility knowledge among presumed fertile males aged ≥16 years of age. Conference abstracts, protocols and studies without sex-disaggregated results for males were excluded. A narrative synthesis without meta-analysis was performed. A total of 4884 records were identified. Five studies (reported in six publications), all conducted in high-income countries, were included. Two were randomized control trials, and three were experimental studies. Interventions were delivered in person by a health professional (n = 3), online and via a mobile app. All studies showed a significant improvement in knowledge of fertility or fertility-related risk factors from baseline to follow-up. The largest improvement was observed for secondary and vocational students. A moderate, long-term retainment of knowledge was observed at two-year follow-up in one study. Available evidence suggests interventions to improve males' fertility knowledge are effective, particularly for younger, less educated males.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"27 1","pages":"2328066"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140143320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of embryo migration after embryo transfer with fresh oocyte donation cycles on pregnancy outcomes. 新鲜卵母细胞捐赠周期胚胎移植后胚胎迁移对妊娠结果的影响。

IF 2.1 4区医学

Human Fertility Pub Date : 2024-12-01 Epub Date: 2024-09-26 DOI: 10.1080/14647273.2024.2406338

Berk Angun, Turkan Gursu, Hale Goksever Celik, Alper Eraslan, John Yeh, Ercan Bastu

{"title":"The effect of embryo migration after embryo transfer with fresh oocyte donation cycles on pregnancy outcomes.","authors":"Berk Angun, Turkan Gursu, Hale Goksever Celik, Alper Eraslan, John Yeh, Ercan Bastu","doi":"10.1080/14647273.2024.2406338","DOIUrl":"https://doi.org/10.1080/14647273.2024.2406338","url":null,"abstract":"Embryo migration is defined as the movement of embryos to implant at the exact site in the endometrial cavity during assisted reproductive technology (ART). We aimed to evaluate the impact of embryo migration on clinical pregnancy (CPR) and live birth rates (LBR) in fresh oocyte donation (OD) cycles. A total of 611 fresh OD cycles was recruited in this prospective cohort study. All embryos were expulsed to upper-middle uterus between 10 and 20 mm from the fundus. Air bubble-fundus distance was measured using ultrasound (USG) at the time of embryo transfer (ET) and then 60 minutes after ET. Patients were divided into 3 groups; first group consisted of patients whose embryos migrated towards fundus, second group whose embryos remained between 10 and 20 mm from fundus and the third group including embryos which migrated towards cervix. There was no significant difference between the groups regarding CPR and LBR (p = 0.359 and p = 0.865, respectively). Our study revealed that embryo migration was a fact and almost 22% of embryos migrated towards the fundus or the cervix. On the other hand, whether the embryo stayed static or migrated, CPR and LBR did not differ significantly in fresh OD cycles.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"27 1","pages":"2406338"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142345722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quality of information for oocyte donors on South African donor agency websites: a content analysis. 南非捐献机构网站上卵细胞捐献者信息的质量：内容分析。

IF 2.1 4区医学

Human Fertility Pub Date : 2024-12-01 Epub Date: 2024-10-14 DOI: 10.1080/14647273.2024.2413531

Karin Hammarberg, Florence Hui-Min Yang, Cal Volks, Andrea Whittaker

{"title":"Quality of information for oocyte donors on South African donor agency websites: a content analysis.","authors":"Karin Hammarberg, Florence Hui-Min Yang, Cal Volks, Andrea Whittaker","doi":"10.1080/14647273.2024.2413531","DOIUrl":"https://doi.org/10.1080/14647273.2024.2413531","url":null,"abstract":"Reproductive travel for gamete donation is becoming increasingly common. South Africa is renowned for its availability and relative affordability of high-quality assisted reproductive technology (ART) services. In South Africa (SA) gamete donation is anonymous by law and donors are compensated. Due to its significant availability of donors, SA is a popular destination for people who need donor gametes. The aim of this study was to assess the quality and comprehensiveness of information for oocyte donors available on donor agency websites in SA. A Google search was performed to compile a list of oocyte donor agency websites and content analysis was used to assess the comprehensiveness of the information for donors. Information on 12 websites was analysed. Overall, wording suggested that oocyte donation is a safe and easy procedure which is a process worth experiencing. Possible physical risks and psychological implications of donating oocytes were either not mentioned or downplayed. No website mentioned if or how donors would be followed up after oocyte retrieval or how they would be cared for in case of complications. No website informed donors about the possibility of genetic testing revealing their identity to a child born from their donation. The lack of transparency about the psychological implications and potential risks of donating oocytes suggests that women who contemplate donating oocytes in SA may not have the information they need to make informed decisions about whether to proceed. Since donor agency websites are potential donors' primary source of information, they should provide comprehensive information about all aspects of oocyte donation. This should include transparent and comprehensive information about the known physical and psychological risks. Donors also need to know that oocyte donation may have unknown long-term health risks and that direct-to-consumer genetic testing may reveal their identity to children conceived through their donation in the future.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"27 1","pages":"2413531"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142464098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysing adherence to guidelines for time-lapse imaging information on UK fertility clinic websites. 分析英国生育诊所网站延时成像信息指南的遵守情况。

IF 1.9 4区医学

Human Fertility Pub Date : 2024-12-01 Epub Date: 2024-05-20 DOI: 10.1080/14647273.2024.2346595

Manuela Perrotta, Letizia Zampino, Alina Geampana, Priya Bhide

{"title":"Analysing adherence to guidelines for time-lapse imaging information on UK fertility clinic websites.","authors":"Manuela Perrotta, Letizia Zampino, Alina Geampana, Priya Bhide","doi":"10.1080/14647273.2024.2346595","DOIUrl":"https://doi.org/10.1080/14647273.2024.2346595","url":null,"abstract":"This study aims to systematically analyze the provision of information on Time-lapse Imaging (TLI) by UK fertility clinic websites. We conducted an analysis of 106 clinic websites that offer fertility treatment to self-funded patients. The analysis aimed to examine whether these clinics offer TLI, the associated cost for patients, and the clarity and quality of the provided information. Out of the 106 websites analysed, 71 (67%) claimed to offer TLI. Among these websites, 25 (35.2%) mentioned charging patients between £300 and £850, 25 (35.8%) claimed not to charge patients, and 21 (29.6%) did not provide any cost information for TLI. Furthermore, 64 (90.1%) websites made claims or implied that TLI leads to improved clinical outcomes by enhancing embryo selection. Notably, 34 (47.9%) websites did not mention or provide any links to the HFEA rating system. It is crucial to provide patients with clear and accurate information to enable them to make fully informed decisions about TLI, particularly when they are responsible for the associated costs. The findings of this study raise concerns about the reliability and accuracy of the information available on fertility clinic websites, which are typically the primary source of information for patients.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"27 1","pages":"2346595"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141070172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spermatogonial quantity in prepubertal boys undergoing fertility preservation is comparable between haematological and non-haematological cancers. 接受生育力保存的青春期前男孩的精原细胞数量在血癌和非血癌之间具有可比性。

IF 1.9 4区医学

Human Fertility Pub Date : 2024-12-01 Epub Date: 2024-06-06 DOI: 10.1080/14647273.2024.2362980

Prathima Tholeti, Sindhura L Koulmane Laxminarayana, Vani R Lakshmi, Vasudeva K Bhat, Vijay Kumar P, Shubhashree Uppangala, Guruprasad Kalthur, Norah Spears, Satish Kumar Adiga

{"title":"Spermatogonial quantity in prepubertal boys undergoing fertility preservation is comparable between haematological and non-haematological cancers.","authors":"Prathima Tholeti, Sindhura L Koulmane Laxminarayana, Vani R Lakshmi, Vasudeva K Bhat, Vijay Kumar P, Shubhashree Uppangala, Guruprasad Kalthur, Norah Spears, Satish Kumar Adiga","doi":"10.1080/14647273.2024.2362980","DOIUrl":"https://doi.org/10.1080/14647273.2024.2362980","url":null,"abstract":"Fertility restoration potential of immature testicular tissue (ITT) depends on the number of spermatogonial cells in the retrieved tissue prior to cryopreservation in oncofertility programme. There are limited data on the association between type of malignancy and testicular germ cell population. Hence, this study is aimed to investigate the spermatogonial and Sertoli cell population in ITT retrieved from 14 pre-pubertal boys who opted for fertility preservation. Histopathological and immunochemical analysis of seminiferous tubules from haematological (N = 7) and non-haematological (N = 7) malignant patients revealed 3.43 ± 2.92 and 1.71 ± 1.81 spermatogonia per tubular cross section (S/T), respectively. The Sertoli cell number was comparable between haematological and non-haematological group (18.42 ± 3.78 and 22.03 ± 10.43). Spermatogonial quantity in ITT did not vary significantly between haematological and non-haematological cancers. This observation, though preliminary, would contribute to the limited literature on paediatric male oncofertility.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"27 1","pages":"2362980"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141261519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum androgen dynamics in young women aged 18-40 treated with chemotherapy for breast cancer: an observational, multicentric, prospective study in France. 接受乳腺癌化疗的 18-40 岁年轻女性的血清雄激素动态：法国的一项多中心前瞻性观察研究。

IF 2.1 4区医学

Human Fertility Pub Date : 2024-12-01 Epub Date: 2024-07-03 DOI: 10.1080/14647273.2024.2350758

S Loubersac, M Chaillot, A Reignier, T Lefebvre, A Dezellus, A Colombel, P Barriere, D Masson, T Freour

{"title":"Serum androgen dynamics in young women aged 18-40 treated with chemotherapy for breast cancer: an observational, multicentric, prospective study in France.","authors":"S Loubersac, M Chaillot, A Reignier, T Lefebvre, A Dezellus, A Colombel, P Barriere, D Masson, T Freour","doi":"10.1080/14647273.2024.2350758","DOIUrl":"10.1080/14647273.2024.2350758","url":null,"abstract":"Although the deleterious impact of chemotherapy regimen used to treat women of reproductive age with breast cancer on ovarian reserve has been extensively studied, hardly anything has been reported on the effect of these protocols on theca cell function and ovarian androgen secretion. The aim of this prospective multicentric cohort study was to describe serum levels of total testosterone and androstenedione during chemotherapy and 24-month follow-up in 250 patients <40 years treated for breast cancer. Mean basal levels of androstenedione and total testosterone at diagnosis were 1.68 ng/mL and 0.20 ng/mL respectively. No correlation with age was found. Serum levels of androstenedione and total testosterone rapidly decreased after chemotherapy completion, before slowly increasing and almost returning to basal levels in all patients during 2-year follow-up. In conclusion our study demonstrates a chemotherapy-induced alteration of ovarian thecal function, resulting in a significant decrease in serum androgen levels. This alteration of theca cell function adds to the well-known alteration of granulosa cell function, resulting in a global, but partly transient, ovarian failure in young women treated for breast cancer. These data bring new insight into ovarian physiology and emphasize the need for pre and post-treatment ovarian follow-up. Trial registration: ClinicalTrial.gov identifier NCT01114464.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"27 1","pages":"2350758"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141491671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diminished ovarian reserve associates with pregnancy and birth outcomes after IVF: a retrospective cohort study. 卵巢储备功能减退与体外受精后妊娠和分娩结果的关系：一项回顾性队列研究。

IF 2.1 4区医学

Human Fertility Pub Date : 2024-12-01 Epub Date: 2024-10-14 DOI: 10.1080/14647273.2024.2414813

Shen Can, Xiaoyan Yang, Ye He, Chao Wang, Huijuan Zou, Qingling Fan, Xiaofeng Xu, Guoqi Cai, Cao Yunxia, Peng Xiaoqing

{"title":"Diminished ovarian reserve associates with pregnancy and birth outcomes after IVF: a retrospective cohort study.","authors":"Shen Can, Xiaoyan Yang, Ye He, Chao Wang, Huijuan Zou, Qingling Fan, Xiaofeng Xu, Guoqi Cai, Cao Yunxia, Peng Xiaoqing","doi":"10.1080/14647273.2024.2414813","DOIUrl":"https://doi.org/10.1080/14647273.2024.2414813","url":null,"abstract":"Antral follicle count (AFC) and serum anti-Müllerian hormone (AMH) are currently the most sensitive and reliable markers of ovarian reserve, but the role of AFC and AMH, as prognosis markers of diminished ovarian reserve (DOR), in pregnancy outcomes after embryo transfer (ET) have been inconsistent. A retrospective cohort study was conducted in a university-affiliated hospital. A total of 4599 women who received their first IVF treatment between January 2012 and December 2019 were included. Uni- and multi-variable regression models were used to determine the association of DOR evaluated by AFC and AMH with pregnancy, number of ET cycles to pregnancy, live birth, preterm birth, and low birth weight. Among the women included, 380 (8.3%) had DOR (i.e. AFC <5 or AMH <1.2 μg/L). After adjusting for confounders, DOR determined by AFC/AMH, AFC alone and AMH alone was associated with a lower pregnancy rate (Risk ratio [RR] 0.81, 95% confidence interval [CI] 0.73-0.89). Among women who were successfully pregnant, DOR evaluated by AFC/AMH but not evaluated by AFC alone or AMH alone was associated with an increased number of ET cycles to pregnancy (Odds ratio 1.43, 95% CI 1.04-1.96). DOR was not associated with the risks of live birth, low birth weight, and preterm birth. Women with DOR may have more difficulty becoming pregnant after IVF treatment, suggesting the predictive role of DOR in pregnancy outcomes before IVF treatment.","PeriodicalId":13006,"journal":{"name":"Human Fertility","volume":"27 1","pages":"2414813"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142464097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0