Healthcare最新文献

{"title":"Effects of Exercise Program on Mental, Pulmonary, and Cardiovascular Health of Elderly Men with Acquired Severe Physical Disabilities: A Retrospective Study.","authors":"Zebin Wen, Yonghwan Kim, Yongchul Choi","doi":"10.3390/healthcare13060597","DOIUrl":"10.3390/healthcare13060597","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Physical activity is recommended for people with physical disabilities and is beneficial not only for physical health but also for mental health. This study aimed to evaluate the quality of life (QoL), pulmonary health, and cardiovascular health among a group of older men with physical disabilities who participated in an exercise program. <b>Methods:</b> This study included 23 participants in the exercise group (EG) as an experimental group and 23 in the culture group (CG) as a control group. All participants were ≥65 years, with one or more physical disabilities, and used wheelchairs or crutches for mobility. The participants were each provided with the exercise program for 8 weeks. Assessments included a QoL, pulmonary function test, brachial-ankle pulse wave velocity (baPWV), and factors of metabolic syndrome. The exercise program consisted of aerobics, strength training using dumbbells and tubes, and mat exercises for three days a week for 8 weeks. The culture program included singing, drawing, and writing. <b>Results:</b> The interaction effects by time and group showed that EG had a superior change compared to CG in QoL (physical function, pain, fatigue, social), forced vital capacity, baPWV, triglycerides, and high-density lipoprotein cholesterol (<i>p</i> < 0.05). <b>Conclusions:</b> Participation in the exercise program positively influenced mental, pulmonary, and cardiovascular health in older men with physical disabilities. Our research results will provide useful information for rehabilitation and social security research to improve the health of elderly people with physical disabilities.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"13 6","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11942334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining Users' Acceptance Intention of Health Applications Based on the Technology Acceptance Model.","authors":"Jae Hyung Park, Chul Won Lee, Chanwook Do","doi":"10.3390/healthcare13060596","DOIUrl":"10.3390/healthcare13060596","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Mobile health applications are essential for improving healthcare access and promoting healthy lifestyles. This study investigates the roles of perceived ease of use, usefulness, and satisfaction in shaping behavioral intentions using the Technology Acceptance Model. <b>Methods:</b> A survey of 329 mobile health application users in Korea was analyzed using confirmatory factor analysis and structural equation modeling to test hypothesized relationships. <b>Results:</b> The findings indicate that perceived ease of use positively influences perceived usefulness (H1). Customer satisfaction is positively influenced by both the perceived ease of use and perceived usefulness (H2 and H3). Furthermore, behavioral intention is affected by perceived ease of use, perceived usefulness, and customer satisfaction (H4 through H6). <b>Conclusions:</b> The findings from this study elucidate how mobile health applications can enhance users' perceptions of ease of use and usefulness, thereby influencing their behavioral intentions through increased satisfaction. This research also advances our understanding of application services and informs the development of effective operational and marketing strategies.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"13 6","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11942198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in Physical Activity Recommendations, Levels of Physical Activity and Main Barriers to Exercise Between Spanish and Polish Cancer Patients.","authors":"Asier Del Arco, Aitor Martinez Aguirre-Betolaza, Iker Muñoz Pérez, Ewa Malchrowicz-Mośko, Mateusz Krystian Grajek, Karolina Krupa-Kotara, Agata Wypych-Ślusarska, Piotr Nowaczyk, Tomasz Urbaniak, Arkaitz Castañeda-Babarro","doi":"10.3390/healthcare13060598","DOIUrl":"10.3390/healthcare13060598","url":null,"abstract":"<p><p><b>Background/Objectives</b>: Physical activity (PA) and exercise have demonstrated numerous benefits for patients with cancer. However, there may be different barriers which vary according to geographical area. The aim of this study was to compare oncologists, PA recommendations, PA patterns and barriers in two different geographical areas. <b>Methods:</b> A total of 254 patients were included, 239 of them women and 15 of them men, while 41.3% of the sample was Polish and 58.7% of the sample Spanish. <b>Results:</b> In terms of differences in time spent on PA per day, the Spanish spent more time walking than the Polish did (<i>p</i> = 0.007). However, no significant differences were found between countries, types or intensity of exercise, and there was a significant relationship between age and type of PA modality (<i>p</i> = 0.002). At the same time, there were different reasons for not practicing PA (<i>p</i> = 0.009). The subsequent analysis showed that younger adults were prone to more vigorous-intensity exercise than the other age groups (<i>p</i> = 0.001, η² = 0.08). Furthermore, there was a significant difference between age groups, countries and sitting time (<i>p</i> = 0.01), with Polish patients spending more time sitting than Spaniards (<i>p</i> = 0.01, η² = 0.06). <b>Conclusions:</b> Although PA patterns in the two countries were similar, the main barriers to exercise differed. Therefore, PA programs should be as personalized as possible (taking into account sociodemographic, cultural and climatic characteristics). Ultimately, to improve the quality of life and health of their patients, oncologists should provide those activities that are most beneficial to their patients.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"13 6","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11942116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Should Artificial Intelligence-Based Patient Preference Predictors Be Used for Incapacitated Patients? A Scoping Review of Reasons to Facilitate Medico-Legal Considerations.","authors":"Pietro Refolo, Dario Sacchini, Costanza Raimondi, Simone S Masilla, Barbara Corsano, Giulia Mercuri, Antonio Oliva, Antonio G Spagnolo","doi":"10.3390/healthcare13060590","DOIUrl":"10.3390/healthcare13060590","url":null,"abstract":"<p><strong>Background: </strong>Research indicates that surrogate decision-makers often struggle to accurately interpret and reflect the preferences of incapacitated patients they represent. This discrepancy raises important concerns about the reliability of such practice. Artificial intelligence (AI)-based Patient Preference Predictors (PPPs) are emerging tools proposed to guide healthcare decisions for patients who lack decision-making capacity.</p><p><strong>Objectives: </strong>This scoping review aims to provide a thorough analysis of the arguments, both for and against their use, presented in the academic literature.</p><p><strong>Methods: </strong>A search was conducted in PubMed, Web of Science, and Scopus to identify relevant publications. After screening titles and abstracts based on predefined inclusion and exclusion criteria, 16 publications were selected for full-text analysis.</p><p><strong>Results: </strong>The arguments in favor are fewer in number compared to those against. Proponents of AI-PPPs highlight their potential to improve the accuracy of predictions regarding patients' preferences, reduce the emotional burden on surrogates and family members, and optimize healthcare resource allocation. Conversely, critics point to risks including reinforcing existing biases in medical data, undermining patient autonomy, raising critical concerns about privacy, data security, and explainability, and contributing to the depersonalization of decision-making processes.</p><p><strong>Conclusions: </strong>Further empirical studies are needed to assess the acceptability and feasibility of these tools among key stakeholders, such as patients, surrogates, and clinicians. Moreover, robust interdisciplinary research is needed to explore the legal and medico-legal implications associated with their implementation, ensuring that these tools align with ethical principles and support patient-centered and equitable healthcare practices.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"13 6","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11942106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Perspectives of General Practitioners on the Roles and Competences of Nurses During a Euthanasia Process: A Cross-Sectional Study.","authors":"Dennis Demedts, Rosalie-Marianne Mathé, Johan Bilsen","doi":"10.3390/healthcare13060595","DOIUrl":"10.3390/healthcare13060595","url":null,"abstract":"<p><p><b>Background:</b> The legalization of euthanasia in Belgium in 2002 positioned nurses as possible participants in the euthanasia process. However, ethical and legal dilemmas necessitate clear definitions of their roles and competencies in this context. Given that general practitioners (GPs) are the primary medical professionals performing euthanasia, understanding their perspectives on the roles of nurses is crucial. <b>Aim:</b> This study aims to describe GPs' perceptions of the roles and competencies of nurses during the euthanasia process. The research question addressed is as follows: \"What are GPs' views on the roles and competencies of nurses in euthanasia?\". <b>Methods:</b> A quantitative cross-sectional survey was conducted among licensed GPs in Flanders, Belgium. Data were collected via an online survey using Qualtrics and analyzed with SPSS Statistics. Ethical approval was obtained from the Medical Ethics Committee of the university. <b>Results:</b> The study included responses from 237 GPs. GPs value the roles and competencies of nurses, recognizing euthanasia as a multidisciplinary process. They acknowledge the critical support nurses provide to patients and their families. GPs assert that the administration of euthanasia medication should remain the exclusive responsibility of the GP. The analysis further indicated that demographic factors did not significantly influence the results. <b>Discussion/Conclusions:</b> GPs in Belgium generally rated the roles and competencies of nurses positively. Enhancing multidisciplinary collaboration, legislating the roles of nurses, and incorporating practical euthanasia training in nursing curricula, e.g., via simulations, are recommended.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"13 6","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11942348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study on 10-Week Combined Aerobic and Resistance Training Exercise Prescription for Female Patients with Pelvic Floor Dysfunction.","authors":"Lu Zhang, Jingbo He, Quancheng Zhang, Ling Wang","doi":"10.3390/healthcare13060592","DOIUrl":"10.3390/healthcare13060592","url":null,"abstract":"<p><p><b>Background/Objectives</b>: Female pelvic floor dysfunction (FPFD) is a prevalent condition affecting postpartum women. This study aims to evaluate the effectiveness of a 10-week combined aerobic and resistance training exercise prescription in improving pelvic floor muscle strength and function in postpartum women with FPFD. <b>Methods</b>: Thirty postpartum women diagnosed with FPFD underwent a 10-week exercise intervention. This study adopted a single-group pre-post design. Pelvic floor muscle electromyography assessment indicators were measured before and after the intervention. <b>Results</b>: The exercise intervention significantly improved the maximum value of fast-twitch muscle fibers (type II) and the average value of slow-twitch muscle fibers (type I) while reducing resting tension and variability. <b>Conclusions</b>: A 10-week combined aerobic and resistance training exercise prescription effectively improves pelvic floor muscle strength in postpartum women. It enhances the maximum value of fast-twitch (type II) muscle fibers, reduces rise and recovery times, and improves slow-twitch (type I) muscle fiber function, including increasing the mean value and reducing variability, rise time, and recovery time.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"13 6","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11942542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined Physical-Cognitive Therapies for the Health of Older Adults with Mild Cognitive Impairment: A Systematic Review and Meta-Analysis.","authors":"Juan Miguel Muñoz-Perete, María Del Carmen Carcelén-Fraile, Javier Cano-Sánchez, Agustín Aibar-Almazán, Yolanda Castellote-Caballero, María Aurora Mesas-Aróstegui, Andrés García-Gutiérrez, Fidel Hita-Contreras","doi":"10.3390/healthcare13060591","DOIUrl":"10.3390/healthcare13060591","url":null,"abstract":"<p><p><b>Background:</b> Mild cognitive impairment (MCI) represents an early stage of cognitive loss that significantly increases the risk of dementia. The aim of this study was to comprehensively synthesize the current evidence on the effect of combined physical and cognitive therapies in older adults with MCI. <b>Methods:</b> A systematic review with meta-analysis was conducted by searching for specific keywords in the PubMed, Scopus, Cinhal, and Web of Science databases. This meta-analysis included a total of 2256 participants distributed across 21 studies that evaluated the benefits of combining physical exercise with cognitive stimulation. <b>Results:</b> This review revealed that these types of therapies present a significant improvement in memory, attention, and executive functions. Participants showed notable improvements in these cognitive areas, highlighting the synergistic effects of physical exercise and cognitive stimulation, which exceeded the benefits of each therapy separately. These results contribute to the understanding of how these combined therapies can improve cognitive health in this population, offering robust evidence supporting their application in clinical practice. <b>Conclusions:</b> This meta-analysis shows that combined physical exercise and cognitive stimulation interventions may be an effective strategy for improving cognitive health in older adults with MCI. The findings of this study offer a valuable contribution to the field, highlighting the potential of these combined therapies to prevent cognitive decline and improve the quality of life of this population. The results may be of interest to health professionals and guide future research and clinical applications.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"13 6","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11941773/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Uneven Effect of Rare Diseases on Functional Status and Work Capacity.","authors":"Corina Oancea, Despina Mihaela Gherman, Florina Georgeta Popescu, Sorina Maria Aurelian, Corina Homentcovschi","doi":"10.3390/healthcare13060594","DOIUrl":"10.3390/healthcare13060594","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Background:&lt;/b&gt; Rare diseases are defined as clinical conditions that affect only a small number of persons in a population, considered fewer than 1 per 2000 in the European Union or fewer than 1 per 1600 in the United States They are serious, often chronic and progressive conditions, characterized by a pronounced clinical polymorphism that crosses all medical specialties. Multiple areas of life beyond just physical health are affected with significant impact on patients, families, and healthcare systems. &lt;b&gt;Objective:&lt;/b&gt; To analyze the socio-demographic, medical, and vocational characteristics that correlate with functional status and work disability as a measure of quality of life in rare diseases. &lt;b&gt;Methods:&lt;/b&gt; An observational retrospective study of adults with rare diseases evaluated for eligibility for social insurance rights in the National Institute of Medical Assessment and Work Capacity Rehabilitation Bucharest (INEMRCM, the Romanian abbreviation) over a 5-year period was made. Descriptive analysis was used to present sample characteristics. Means and standard deviations (SD) were calculated to describe numerical variables, frequencies were used to describe categorical variables, and logistic regression analysis was conducted to evaluate potential predictors of work capacity. All statistical analyses were performed by PSPP.3 software. &lt;i&gt;p&lt;/i&gt; &lt; 0.05 was the cut-off for statistical significance with a 95% confidence interval. &lt;b&gt;Results:&lt;/b&gt; 90 consecutive persons were included in the survey. The mean age of the group was 44.5 years ± SD 10.61 years, with a female/male ratio of 48/42 persons. The mean disease duration was 10.61 years ± SD 9.76 years. Men had more severe disease (73.81%); &lt;i&gt;p&lt;/i&gt; = 0.018 and significantly younger retirement age, M/F = 39.10 ± 12.26/43.06 ± 9.32; &lt;i&gt;p&lt;/i&gt; = 0.037. Less disabling diseases were predominant autoimmune conditions (85.71% of cases); genetic conditions had a more severe functional impact in 63.75% of cases; &lt;i&gt;p&lt;/i&gt; = 0.037. People with multisystem diseases but with specific or targeted treatment can work more frequently (76.19%); those with visual impairment have more severe impairments (73.77%); &lt;i&gt;p&lt;/i&gt; &lt; 0.001. All individuals who received specific therapy had a better functional status, unlike only 37.21% of those who received symptomatic treatment or treatment for complications; &lt;i&gt;p&lt;/i&gt; = 0.023. Logistic regression analysis indicated that the type of impairment and the availability of specific treatments could serve as predictors of a reduced likelihood of employment in rare disease cases. Education level and occupation were not correlated with functional impairment and work disability (NS). &lt;b&gt;Conclusions:&lt;/b&gt; Several factors, including some that are modifiable, were associated with better outcomes, such as reduced disability and an increased potential for work participation. Sex, disease etiology, type of impairment, and treatment were all significantly linked to functiona","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"13 6","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11942041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Health Literacy Among Hospitalized Patients: A Cross-Sectional Study in Silesia, Poland.","authors":"Kamila Jaroń, Mateusz Grajek, Joanna Kobza, Mateusz Rozmiarek","doi":"10.3390/healthcare13060593","DOIUrl":"10.3390/healthcare13060593","url":null,"abstract":"<p><p><b>Background:</b> Health literacy includes the basic competencies needed to improve the quality of communication with medical personnel. <b>Objective:</b> The purpose of this study was to analyze the level of health literacy of hospitalized patients and to assess the impact of factors such as age, gender, education, place of residence, the ability to question the doctor about the information provided, and the evaluation of communication with medical personnel on their health literacy. <b>Material and methods:</b> The study was cross-sectional, and a specially designed questionnaire was used to collect data. Patients' level of health literacy was assessed using the functional, communicative, and critical health literacy (FCCHL) scale. The study included 203 independent adult patients. <b>Results:</b> Higher levels of health literacy were observed more often in younger age groups, among women, people with higher education, and residents of large cities. Patients with a higher level of health literacy rated their communication with medical personnel higher, were more active in communicating with doctors, and asked questions more often, indicating that they were more involved in the medical decision-making process. A larger percentage of these patients believed that their consent to medical services was informed compared to patients with lower health literacy. In addition, patients with higher health literacy were more likely to express the belief that the medical staff spent enough time with them during their visit. <b>Conclusions:</b> The study's findings underscore the importance of strengthening health education, which can help reduce health literacy disparities and improve health care quality.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"13 6","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11941875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of Modified Mindfulness Training Program for Antenatal Depression and Perceived Stress Among Expectant Mothers with Male Child Preference.","authors":"Badil, Najma Naz, Dildar Muhammad, Khalid Rehman","doi":"10.3390/healthcare13060584","DOIUrl":"10.3390/healthcare13060584","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Antenatal depression and perceived stress are prevalent mental health challenges faced by pregnant women, and they are associated with male child preference. This study aimed to assess the feasibility of a modified mindfulness training program for reducing antenatal depression and perceived stress levels among expectant mothers with a male child preference at a public sector tertiary care hospital in Karachi, Pakistan. <b>Material and Methods:</b> The present feasibility trial was conducted among expectant mothers with antenatal depression and perceived stress with a male child preference using the ADAPT-ITT framework. Assessments of the needs and experiences of the new target population were carried out through an exploratory and descriptive qualitative study. In-depth interviews were conducted using a semi-structured interview guide and analyzed using a thematic analysis process. Repeated-measures MANOVA was employed to investigate the effect of time on antenatal depression and perceived stress scores in the feasibility of the intervention. <b>Results:</b> Five major themes emerged from the qualitative data. A significant influence of time was established on the antenatal depression scores, with perceived scores of F (2, 326) = 21.244, <i>p</i> < 0.001, and F (2, 326) = 310.748, <i>p</i> < 0.001. The antenatal depression scores significantly decreased from pre-intervention to post-intervention (mean difference = 4.00, <i>p</i> < 0.001), and there was a slightly significant decline from post-intervention to follow-up (mean difference = 1.167, <i>p</i> = 0.001). The perceived stress scores were significantly reduced from pre-intervention to post-intervention (mean difference = 10.214, <i>p</i> < 0.001), and there was a minor but significant decline from post-intervention to follow-up (mean difference = 0.333, <i>p</i> = 0.043). <b>Conclusions:</b> This study concludes that the modified mindfulness training program is a culturally suitable, contextually relevant intervention in the context of Pakistan and it significantly reduced antenatal depression and perceived stress in expectant mothers with a male child preference. The modified mindfulness training program was modified in accordance with the context of Islamic teaching regarding health-promoting lifestyles and religious spirituality.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"13 6","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11942594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}