Associations Between Metabolic Risk Factors and Lung Function Among Adults in Northern Thailand: A Cross-Sectional Study.

IF 2.7 4区医学 Q2 HEALTH CARE SCIENCES & SERVICES

Healthcare Pub Date : 2025-07-10 DOI:10.3390/healthcare13141671

Anurak Wongta, Nan Ei Moh Moh Kyi, Muhammad Samar, Nyan Lin Thu, Tipsuda Pintakham, Surat Hongsibsong

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引用次数: 0

Abstract

Background/objectives: Lung function decline is influenced by metabolic risk factors (e.g., obesity, hyperglycemia, dyslipidemia) and environmental exposures (e.g., PM2.5), which may jointly contribute to airway inflammation and lung function impairment. This study aimed to investigate these associations in northern Thai adults and identify factors linked to lung function impairment.

Methods: A cross-sectional study was conducted in San Pa Thong, Chiang Mai, Thailand, involving 137 adults. Data on metabolic indicators and spirometry were collected. Statistical analyses included Spearman's correlation, multivariable linear regression, and logistic regression.

Results: Higher triglyceride levels and shorter 6-min walk test (6MWT) distances were associated with reduced forced expiratory volume in one second (FEV₁) and forced vital capacity (FVC). Only 6MWT distance remained a significant factor for lung function impairment in logistic regression (adjusted OR = 0.763, 95% CI: 0.588-0.990, p = 0.042).

Conclusions: Combining metabolic and respiratory assessments may improve early detection of lung function impairment in high-risk populations, particularly given the dual burden of metabolic disorders and air pollution in northern Thailand. These findings support the integration of metabolic and respiratory screening in community health programs to enhance preventive strategies.

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泰国北部成人代谢危险因素与肺功能之间的关系：一项横断面研究

背景/目的：肺功能下降受代谢危险因素（如肥胖、高血糖、血脂异常）和环境暴露（如PM2.5）的影响，这些因素可能共同导致气道炎症和肺功能损害。本研究旨在调查泰国北部成年人的这些关联，并确定与肺功能损害相关的因素。方法：在泰国清迈的新巴通进行横断面研究，涉及137名成年人。收集代谢指标和肺活量测定数据。统计分析包括Spearman相关、多变量线性回归和逻辑回归。结果：较高的甘油三酯水平和较短的6分钟步行测试（6MWT）距离与一秒钟用力呼气量（FEV1）和用力肺活量（FVC）降低有关。在logistic回归中，只有6MWT距离仍然是肺功能损害的显著因素（校正OR = 0.763, 95% CI: 0.588-0.990, p = 0.042）。结论：结合代谢和呼吸评估可以改善高危人群肺功能障碍的早期发现，特别是考虑到泰国北部代谢紊乱和空气污染的双重负担。这些发现支持在社区健康项目中整合代谢和呼吸筛查，以加强预防策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Healthcare Medicine-Health Policy

CiteScore

3.50

自引率

7.10%

发文量

审稿时长

47 days

期刊介绍： Healthcare (ISSN 2227-9032) is an international, peer-reviewed, open access journal (free for readers), which publishes original theoretical and empirical work in the interdisciplinary area of all aspects of medicine and health care research. Healthcare publishes Original Research Articles, Reviews, Case Reports, Research Notes and Short Communications. We encourage researchers to publish their experimental and theoretical results in as much detail as possible. For theoretical papers, full details of proofs must be provided so that the results can be checked; for experimental papers, full experimental details must be provided so that the results can be reproduced. Additionally, electronic files or software regarding the full details of the calculations, experimental procedure, etc., can be deposited along with the publication as “Supplementary Material”.