Health physicsPub Date : 2025-02-01Epub Date: 2024-09-04DOI: 10.1097/HP.0000000000001884
Haegin Han, Jaehyo Kim, Sungho Moon, Gahee Son, Bangho Shin, Hyeonil Kim, Suhyeon Kim, Chansoo Choi, Chan Hyeong Kim
{"title":"MPPD: A User-Friendly Posture Deformation Program for Mesh-Type Computational Phantoms.","authors":"Haegin Han, Jaehyo Kim, Sungho Moon, Gahee Son, Bangho Shin, Hyeonil Kim, Suhyeon Kim, Chansoo Choi, Chan Hyeong Kim","doi":"10.1097/HP.0000000000001884","DOIUrl":"10.1097/HP.0000000000001884","url":null,"abstract":"<p><strong>Abstract: </strong>Recently, the International Commission on Radiological Protection (ICRP) released adult Mesh-type Reference Computational Phantoms (MRCPs), which have great advantage in high deformability. Previous studies have exploited their high deformability to investigate the dosimetric influence of varying statures and postures, demonstrating significant variations in radiation doses. However, the previous studies are constrained by their inability to consider both stature and posture concurrently and by the limited range of postures analyzed. In the present study, a computer program named MPPD (Mesh-type Phantom Posture Deformer) was developed, a user-friendly graphical user interface that enables users to adjust the posture of adult MRCPs and corresponding library phantoms. The MPPD program was applied to deform five adult male phantoms of different statures into sitting and kneeling postures, showcasing its rapid computational speed and minimal RAM usage. The effectiveness of the MPPD program for dose calculation was also investigated by computing the detriment-weighted doses for MPPD-deformed adult male MRCPs, which showed good agreement with dose values for existing posture-deformed phantoms of the previous study. Furthermore, as an application of the MPPD program, the combined dosimetric impact of stature and posture was investigated, which is the inaugural effort to estimate doses by considering these factors concurrently. The result showed that the impact of stature and posture on radiation doses could largely vary depending on the radiation source, highlighting the importance of simultaneous consideration of stature and posture for accurate dose estimation.</p>","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":"122-132"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health physicsPub Date : 2025-02-01Epub Date: 2024-11-08DOI: 10.1097/HP.0000000000001902
Richard A Tell, Robert Kavet
{"title":"An Alternative Approach for Evaluating Induced and Contact Currents for Compliance with Their Exposure Limits (100 kHz to 110 MHz) in IEEE Std C95.1-2019.","authors":"Richard A Tell, Robert Kavet","doi":"10.1097/HP.0000000000001902","DOIUrl":"10.1097/HP.0000000000001902","url":null,"abstract":"<p><strong>Abstract: </strong>The Institute of Electrical and Electronics Engineers establishes exposure reference levels ( ERL s) for electric fields ( E -fields) (0-300 GHz) and both induced ( I IND ) and contact currents ( I SC ) (<110 MHz) in its standard, IEEE Std C95.1™-2019 (IEEE C95.1). The \"classical\" scenarios addressed in IEEE C95.1 include a free-standing, grounded \"reference\" person ( I IND ) or an ungrounded reference person in manual contact with an adjacent grounded conductor ( I SC ), each exposed to a vertically oriented E -field driving the currents. The ERL s for current from 100 kHz to 110 MHz were established to limit heating in the finger (from touch), ankle ( I IND ), and wrist ( I SC from grasp contact), specifying the 6-min average specific absorption rate ( SAR , W kg -1 ) as the dosimetric reference limit ( DRL ); whole-body E -field ERL s are 30-min averages. The DRLs were established assuming a default \"effective\" local cross-section (9.5 cm 2 ) and consistent with a composite tissue conductivity of ~0.5 S m -1 . A previous publication described the misalignment of the ERL s for E -fields with the ERL s for I IND (which extends to I SC ) and also proposed a ramped E -field ERL from 100 kHz to 30 MHz. For the frequency range 100 kHz to 110 MHz, this paper proposes temperature increase ( ΔT ) in ankle and wrist as the preferred effect metric associated with I IND and I SC ; applying the E -field ERL s as surrogates for limits to these currents; and adopting the proposed ramp. The analysis of ΔT is based on the tissue mix in realistic anatomic depictions of ankle and wrist cross-sections; relevant tissue properties posted online; published tissue perfusion data; and anthropometric data on a large sample of male and female adults in the US military, allowing an estimate of effects over a range of body size. To evaluate ΔT versus frequency and time, the Penne bioheat equation was adapted with convective cooling from arterial blood as the lone cooling mechanism. The analysis revealed that I IND s and I SC s induced by ERL -level E -fields produce SAR s in excess of the local DRL s (in some cases far exceed). Calculations of time to ΔT of 5 °C, reflective of a potentially adverse (painful) response, resulted in worst-case times for effects in the ankle on the order of minutes but on the order of 10s of s in wrist. Thus, compliance with the E -field ERL , as assessed as a 30-min whole-body average is incompatible with the time course of potentially adverse effects in ankle and wrist from I IND and I SC , respectively. Further analysis of the relevant exposure/dose scenarios and consensus of stakeholders with a multi-disciplinary perspective will enable the development of a revised standard, practical from a compliance perspective and protective of all persons.</p>","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":"156-166"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health physicsPub Date : 2025-01-31DOI: 10.1097/HP.0000000000001957
Tingyu Yang, Rong Gao, Yehui Gao, Mingyue Huang, Jialu Cui, Lin Lin, Hongbo Cheng, Wanyun Dang, Yue Gao, Zengchun Ma
{"title":"The Changes of Lymphocytes and Immune Molecules in Irradiated Mice by Different Doses of Radiation.","authors":"Tingyu Yang, Rong Gao, Yehui Gao, Mingyue Huang, Jialu Cui, Lin Lin, Hongbo Cheng, Wanyun Dang, Yue Gao, Zengchun Ma","doi":"10.1097/HP.0000000000001957","DOIUrl":"https://doi.org/10.1097/HP.0000000000001957","url":null,"abstract":"<p><strong>Abstract: </strong>The effects of different radiation doses on T and B lymphocyte functional subsets and the changes of immune cells and immune molecules were observed in mice at different times post-irradiation to provide a theoretical basis for the changes of immune cells affected by radiation. In this study, the changes of T and B immune cells and immune-related molecules were observed at 1, 3, 7, 14, and 21 d after single irradiation of 2 Gy, 4 Gy, and 6 Gy. The results showed that white blood cells (WBC), lymphocytes (LYMPH), and lymphocyte percentage (LYMPH%) in peripheral blood of mice were significantly reduced and reached the lowest point 3 d after irradiation. Flow cytometry results showed that the percentages of CD3+T and CD8+/CD3+T lymphocytes in spleen and thymus were significantly decreased, and the percentages of CD19+B lymphocytes in spleen and CD4+/CD3+T lymphocytes in thymus were also decreased. However, the percentages of splenic NK cells, CD4+/CD3+T cells, and CD4+/CD8+ ratios in spleen and thymus were increased. Most of the indicators fell to the lowest or highest point 3 d after irradiation, indicating that immune function was suppressed at this time. From 7 to 21 d after irradiation, most immune cells gradually recovered. Single irradiation of 2 Gy, 4 Gy, and 6 Gy increased the contents of IL-1β, IL-2, IL-6, IL-17, TNF-α, TGF-β, and IFN-γ in serum of mice and decreased the contents of anti-inflammatory factors IL-4 and IL-10. The serum levels of immunoglobulin IgA, IgG, IgM and complement C3, C4 were significantly increased after irradiation. Our study showed that a single dose of 2 Gy, 4 Gy, and 6 Gy induced immunosuppression in mice, and maximum immunosuppression was achieved 3 d after irradiation. At this time, CD19+B lymphocytes were the most sensitive, followed by CD3+T lymphocytes, and NK cells were the most resistant. The radiosensitivity of CD8+/CD3+T lymphocytes was slightly higher than that of CD4+/CD3+T lymphocytes.</p>","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health physicsPub Date : 2025-01-28DOI: 10.1097/HP.0000000000001955
Lienard Chang, Daniel Kim
{"title":"Radiation Dose to Occupational Dosimeters Brought on Commercial Air Travel.","authors":"Lienard Chang, Daniel Kim","doi":"10.1097/HP.0000000000001955","DOIUrl":"https://doi.org/10.1097/HP.0000000000001955","url":null,"abstract":"<p><strong>Abstract: </strong>Occupational radiation dosimeters that return high readings cannot always be explained by circumstances in the workplace. For this experiment, a series of optically stimulated luminescence (OSL) dosimeters were brought to airports to estimate the radiation dose OSLs would receive should a worker accidentally bring their dosimeter with them during travel. The OSLs returned readings between 0.77 and 3.70 mSv. While factors such as scanning times, machine modality and model, flight duration, and elevation changes can all affect dosimeter readings, this small experiment provides a general range of dose readings to dosimeters to assist radiation safety program managers in quantifying true radiation dose from the workplace.</p>","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143058810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health physicsPub Date : 2025-01-16DOI: 10.1097/HP.0000000000001947
Alaa Mujahid, Bashayr Alotaibi, Chloe DeMellier, Carlos Gallegos, Mohammad Sherwani, Ara Alexandrian, Anna Sorace, Amy Brady, Remo George
{"title":"Characterization of Cutaneous Radiation Syndrome in a Mouse Model Using [18F]F- Fluorodeoxyglucose Positron Emission Tomography.","authors":"Alaa Mujahid, Bashayr Alotaibi, Chloe DeMellier, Carlos Gallegos, Mohammad Sherwani, Ara Alexandrian, Anna Sorace, Amy Brady, Remo George","doi":"10.1097/HP.0000000000001947","DOIUrl":"https://doi.org/10.1097/HP.0000000000001947","url":null,"abstract":"<p><strong>Abstract: </strong>Ionizing radiation on the skin has the potential to cause various sequelae affecting quality of life and even leading to death due to multi-system failure. The development of radiation dermatitis is attributed to oxidative damage to the skin's basal layer and alterations in immune response, leading to inflammation. Past studies have shown that [18F]F-2-fluoro-2-deoxyglucose positron emission tomography-computed tomography ([18F]F-FDG PET/CT) can be used effectively for the detection of inflammatory activity, especially in conditions like hidradenitis suppurativa, psoriasis, and early atherosclerosis. Since currently there are no specific tests for radiation dermatitis, our study aimed to validate whether radiation dermatitis induced in mice can be accurately visualized and measured using [18F]F-FDG PET/CT. We induced cutaneous radiation syndrome in BALB/c mice with different radiation absorbed doses and monitored symptom development through photography, PET imaging, and histopathology, marking the first attempt at non-invasively quantifying radiation dermatitis effects at the molecular level using PET imaging. Our results showed that there were progressive changes in the dorsal skin of irradiated mice, with notable differences between those exposed to varying doses of radiation. Erythema, epilation, and desquamation were more pronounced in mice exposed to lower doses (25 Gy and 35 Gy) than at 45 Gy; however, by the third week, severe skin deterioration, including ulceration and dermal atrophy, was evident in mice irradiated with 35 Gy and 45 Gy. PET/CT imaging revealed increased [18F]F-FDG uptake in the irradiated dorsal skin area of all mice compared to controls, with more pronounced avidity for the lesion in the 25 Gy and 35 Gy than the 45 Gy. Comparison of tissue-normalized SUVMax values showed that both the 25 Gy and 35 Gy mice exhibited fourfold [18F]F-FDG uptake in the dorsal skin compared to controls, while a twofold uptake was seen at 45 Gy, thus indicating substantial metabolic changes in the dorsal skin induced by radiation exposure. Histopathological analyses correlated with the above findings, demonstrating generalized hypertrophy and epidermal thickening in all irradiated mice compared to controls, with thicker epidermis observed with higher radiation doses and increased destruction of microvasculature. In conclusion, PET/CT emerges as a successful tool for imaging cutaneous radiation syndrome, with the observed dermal changes in irradiated mice closely aligning with metabolic alterations of the affected area.</p>","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143004508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis Method of 131I Activity in Carbon Cartridge and Internal Dose Assessment for Nuclear Medicine Workers.","authors":"Shuo Wang, Fei Tuo, Jian-Feng Zhang, Xiao-Liang Li, Bao-Lu Yang, Qiang Zhou, Ze-Shu Li, Shu-Ying Kong, Wei-Hao Qin","doi":"10.1097/HP.0000000000001954","DOIUrl":"https://doi.org/10.1097/HP.0000000000001954","url":null,"abstract":"<p><strong>Abstract: </strong>Inhalation of 131I is the main route for internal doses to nuclear medicine workers. This study aimed to establish a simple analysis method for determining 131I activity in carbon cartridges, explore the activity concentration of 131I in nuclear medicine departments, and evaluate the internal dose of workers. A total of 21 nuclear medicine departments in the hospital conducted air sampling using a high-volume air sampler equipped with carbon cartridges and glass fiber filters to collect gaseous 131I and aerosol 131I, respectively. Furthermore, a mathematical model was developed to analyze the 131I activity with inhomogeneous distribution in cartridges. Based on the 131I activity measured by the HPGe γ spectrometer, the personal annual inhalation effective dose was estimated. The results showed that there is a significant difference in the activity of gaseous 131I and aerosol 131I, with the activity ranging from 1.5±0.08 Bq m-1 to 3,944.23±197.21 Bq m-3 and ND (not detectable) to 842.11±42.11 Bq m-3, respectively. The activity of aerosol 131I is about 1% to 7% of that of gaseous 131I. The annual committed effective dose caused by inhalation of 131I for workers is 3.6 μSv to 8.23 mSv, which is lower than the dose limit of 20 mSv y-1. In general, the 131I contamination in the nuclear medicine department cannot be ignored, and the concentration of 131I should be regularly monitored to prevent and control the internal radiation to which workers may be exposed.</p>","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health physicsPub Date : 2025-01-13DOI: 10.1097/HP.0000000000001935
Jerrold T Bushberg, Matthew J Butcher
{"title":"Measurement of Ambient Millimeter Wave Exposure Levels around Small Base Stations.","authors":"Jerrold T Bushberg, Matthew J Butcher","doi":"10.1097/HP.0000000000001935","DOIUrl":"https://doi.org/10.1097/HP.0000000000001935","url":null,"abstract":"<p><strong>Abstract: </strong>This study investigated the implementation and impact of fifth-generation (5G) wireless millimeter wave (mmW) technology. 5G offers significant advancements over previous generations and supports additional frequency bands, including mmW, to enhance mobile broadband with ultra-reliable, low-latency communications, supporting a high volume of diverse communications. This technology is expected to enable billions of new connections in the Internet of Things (IoT), fostering innovations in various sectors including healthcare, manufacturing, and education. This research contributes to the understanding and safe implementation of this transformative technology. Global adoption of 5G is rapidly increasing, with over 1.5 billion subscriptions as of 2024, projected to reach 58% of all wireless subscriptions by 2029. Despite its benefits, 5G mmW installations have raised concerns regarding exposure to electromagnetic fields. This study was conducted using a dual-polarized horn antenna and relatively inexpensive spectrum analyzers to measure typical ambient mmW radiofrequency field power densities near operational radio base stations (RBS) in urban and suburban environments. The measurements were taken at various times of the day and in different weather conditions to ensure a comprehensive understanding of the ambient mmW exposure. The study's results provide reassuring evidence that the ambient mmW exposure from RBSs is significantly lower than the safety limits set by the Federal Communications Commission (FCC) and other international standards. The exposure levels ranged from 0.0003% to 0.0082% of the public maximum permissible exposure (MPE), with the highest levels being more than 25,000 times lower than the allowed continuous public exposure. This study concludes that typical mmW exposure from 5G RBSs is minimal and substantially below established safety limits.</p>","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142978062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health physicsPub Date : 2025-01-10DOI: 10.1097/HP.0000000000001920
John Mauro, Joseph Porrovecchio, William Amann, Stephen Marschke, Michael S Brightwell, Ron Davison, Duane DeMore, Amy Mangel, Lynn Anspaugh, Adela Salame-Alfie, Armin Ansari
{"title":"Supplemental Operational Guidance for Minimizing Potential Inhalation Doses to Workers and Volunteers at Community Reception Centers and Public Shelters.","authors":"John Mauro, Joseph Porrovecchio, William Amann, Stephen Marschke, Michael S Brightwell, Ron Davison, Duane DeMore, Amy Mangel, Lynn Anspaugh, Adela Salame-Alfie, Armin Ansari","doi":"10.1097/HP.0000000000001920","DOIUrl":"https://doi.org/10.1097/HP.0000000000001920","url":null,"abstract":"<p><strong>Abstract: </strong>In the event of a nuclear explosion in an urban environment, contaminated persons may be directed to Community Reception Centers (CRC) and/or public shelters. This paper is a companion document to a previous paper that addresses the inhalation hazard to workers at a CRC from resuspension of fallout from the evacuees. To limit the inhalation hazard evacuees must be screened to prevent severely contaminated persons from entering a CRC. The suggested screening level is 10,000 dpm cm-2 and rapid methods of screening arriving evacuees are presented. Practical advice is provided on methods that can be used to limit contamination within a CRC. These methods include alterations to heating and cooling systems and the implementation of monitoring strategies to guard against unexpected increases in airborne activity levels.</p>","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health physicsPub Date : 2025-01-10DOI: 10.1097/HP.0000000000001952
Brianna H Matthews, Stephen Noble
{"title":"Nuclear Waste Tank Emission Contributions to Particle Size Distribution.","authors":"Brianna H Matthews, Stephen Noble","doi":"10.1097/HP.0000000000001952","DOIUrl":"https://doi.org/10.1097/HP.0000000000001952","url":null,"abstract":"<p><strong>Abstract: </strong>Pollutants from anthropogenic activities including industrial processes are ubiquitous to the environment. To understand the impact from industrial aerosol on climate and human health, industrial aerosol needs to be better characterized. In this study, particle number concentrations were used as a proxy for atmospheric pollutants, which include both particles and gases. Particle concentration and size distribution were measured using a scanning mobility particle sizer (SMPS) approximately 4.5 km from primary industrial areas at the Savannah River Site in Aiken, SC. Industrial areas include numerous nuclear waste storage and processing tanks. The SMPS data were divided into two groups depending on the wind direction measured onsite to categorize transport from the industrial area or from elsewhere. Industrial contributions were found to have a higher concentration of particles with sizes less than 200 nm, 859 ± 564 cm-3, in comparison to non-industrial attributed particles, 733 ± 495 cm-3 on average from March-July 2021. For sizes larger than 200 nm, industrial and non-industrial particles have a similar concentration, 89 ± 59 cm-3 and 99 ± 61 cm-3, with non-industrial concentrations being slightly larger. To confirm that industrial particles could travel to the sampling location, air dispersion modeling was completed for specific case studies during the sampling period. The atmospheric dispersion modeling results confirmed that particles released at the industrial areas reached the sampling location when the wind direction was favorable for transport from the industrial areas. The greater concentration of smaller-sized particles in industrial emissions has implications for typical particulate measurements (PM2.5), heath impacts, and climatological influences.</p>","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health physicsPub Date : 2025-01-09DOI: 10.1097/HP.0000000000001946
Gang Liu, Ye Li, XiaoQin Wu, YinYin Liu, Rong Zhang, LiMei Niu, Xue Zhang, Jinhan Wang, Yeqing Gu
{"title":"Risk Estimation of Carcinogenic and Noncarcinogenic Diseases from Radiation for Medical X-ray Workers.","authors":"Gang Liu, Ye Li, XiaoQin Wu, YinYin Liu, Rong Zhang, LiMei Niu, Xue Zhang, Jinhan Wang, Yeqing Gu","doi":"10.1097/HP.0000000000001946","DOIUrl":"https://doi.org/10.1097/HP.0000000000001946","url":null,"abstract":"<p><strong>Abstract: </strong>The objective of this paper is to construct a follow-up cohort of medical x-ray workers and analyze the risk estimates of radiation-induced carcinogenic and noncarcinogenic diseases induced by chronic low-dose ionizing radiation exposure in the follow-up cohort. A fixed cohort study was used. A total of 159 medical x-ray workers working in radiology departments of hospitals in Gansu Province from 1950 to 1980 were selected as the radiology group, and 149 medical workers in internal medicine, surgery, and other departments who had not engaged in radiology work at the same hospital were selected as the control group. A fifth follow-up survey was also conducted. Information on personal radiation exposure history, lifestyle and morbidity was collected for 310 medical x-ray workers and the control group. Malignant tumors and noncancerous diseases (cataracts, diabetes, aplastic anemia, hypertension, coronary heart disease, cerebral apoplexy, etc.) were used as endpoints to analyze the risk estimates of carcinogenic and noncancerous diseases caused by low-dose radiation. There were 14 patients with malignant tumors, 8 in the radiation group and 6 in the control group (RR=1.25); 11 cases of cataract, radiation group, 8 cases, control group, 3 cases, RR:2.50; 18 patients with diabetes mellitus, 12 in the radiation group and 6 in the control group (RR = 1.87); 25 hypertensive patients, 17 in the radiation group and 8 in the control group (RR = 1.99); 23 patients with CHD, 12 in the radiation group and 11 in the control group (RR = 1.02); and 15 cerebral apoplexy patients, 5 in the radiation group and 10 in the control group (RR=0.47).Compared with the control group, the differences were statistically significant (P<0.01). The risk factors for CR and noncarcinogenic diseases associated with low-dose radiation were cataracts (RR: 2.50) > hypertension (RR: 1.99) > diabetes (RR: 1.87) > malignancy (RR: 1.25) > CHD (RR: 1.02) > cerebral apoplexy (RR: 1.02). 0.47. Compared with those in the control group, medical x-ray workers had an increased risk of developing malignant tumors and cataracts, which may be related to occupational exposure to chronic low-dose ionizing radiation. Therefore, radiation workers should pay attention to the optimization of protection in radiation work practice. The incidences of hypertension and diabetes are increased, and the incidences of CHD are basically the same; in particular, the incidence of cerebral apoplexy is significantly reduced, indicating that cerebral apoplexy has a certain protective effect on medical x-ray workers.</p>","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}