Heliyon最新文献

{"title":"Damage assessment of the Asian corn borer, <i>Ostrinia furnacalis</i> (Lepidoptera: Crambidae), in corn production centers in Indonesia.","authors":"Y Andi Trisyono, Valentina E F Aryuwandari, Nike G H Sinulingga, Ignatius Putra Andika","doi":"10.1016/j.heliyon.2025.e42795","DOIUrl":"10.1016/j.heliyon.2025.e42795","url":null,"abstract":"<p><p><i>Ostrinia furnacalis</i> (Guenée) is known as an insect pest in Indonesian corn production. This study aimed to determine the existing and potential damage due to this insect in four major corn production provinces: East and Central Java, Lampung, and North Sumatra. Twenty sites per province were selected and these sites were distributed in three districts in each province. Observations were done during the vegetative and reproductive stages. The potential damage was assessed by observing four heavily infested sites selected in Central Java and Lampung. The proportion of plants infested varied from 50 to 53 % and 35-64 % during the vegetative and reproductive stages, respectively. Average number of holes per stalk was 2.36 holes/stalk in Central Java followed by 1.40 holes/stalk in Lampung, 1.21 holes/stalk in North Sumatra, and 0.60 holes/stalk in East Java. Most holes were found on nodes above the ear (91.6 %) while most galleries had lengths ranging from 4 to 6 cm. In heavily infested fields, infested stalks reached 95 % with an average of 3 holes/stalk. Due to the potential damage that this pest may cause, effective and preventive management strategies should be planned and implemented to reduce the damage and prevent this insect from reaching its potential yield loss.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 4","pages":"e42795"},"PeriodicalIF":3.4,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11904569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conceptualizing green finance: Findings from textual and network analysis.","authors":"Karambir Singh Dhayal, Srijan Shashwat, Arun Kumar Giri","doi":"10.1016/j.heliyon.2025.e42785","DOIUrl":"10.1016/j.heliyon.2025.e42785","url":null,"abstract":"<p><p>Green finance has seen increased attention from academic researchers and policymakers due to its relevance in mitigating climate change and achieving environmental sustainability goals. Despite the exponential rise in its research publications and policy articles, there remains a lack of uniformity in the scholarly understanding of green finance. The lack of proper understanding and fragmented definitions further impede this domain's theoretical and practical advancements. Thus, it brings much subjectivity to green finance research as it becomes manipulated through different definitions. The current study addresses this significant research gap by systematically analyzing 126 green finance definitions sourced from research articles and different organizational reports of international repute. Through advanced textual analysis, co-word network analysis, and topic modelling through latent dirichlet allocation, the present study identifies the key dimensions of green finance and their interrelationships, culminating in a better understanding of these definitions. The study findings reveal ten core dimensions: environmental, sustainability, energy, finance, economic, institutional, technology, green, societal and sectoral, highlighting their centrality in shaping the existing green finance research definitions. The present study makes a significant critical contribution to advance the scholarly discourse on green finance by providing a strong foundation through the data-driven analysis of the existing definitions. It has significant practical implications, offering a standardized conceptual framework that policymakers, financial institutions, and international organizations can adopt to design sustainable financial products, align regulatory frameworks, and foster global collaboration.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 4","pages":"e42785"},"PeriodicalIF":3.4,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11904483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel signature predicts prognosis in pancreatic cancer based on tumor membrane-associated genes.","authors":"Zhaowei Ding, Jun Wu, Yongqing Ye, Yunlong Zhong, Lei Yan, Ping Wang","doi":"10.1016/j.heliyon.2025.e42791","DOIUrl":"10.1016/j.heliyon.2025.e42791","url":null,"abstract":"<p><strong>Background: </strong>Pancreatic cancer is one of the leading causes of tumor-related mortality, characterized by short patient survival times and limited treatment options. Some targeted therapies have not succeeded in improving patient prognosis. Tumor membranes possess potential target specificity, offering hope for enhancing the efficacy of immunotherapy and drug treatment.</p><p><strong>Methods: </strong>In this study, we collected gene expression and survival data from two scRNA-seq projects and patient cohorts in TCGA, ICGC, and GEO. Differential analysis and dimensionality reduction clustering were employed to isolate tumor epithelial cells. High-expression membrane-associated genes in tumor epithelial cells were identified through PPI network analysis and functional enrichment. Subsequently, membrane-associated genes associated with patient prognosis were selected using LASSO and Cox regression to construct MaGPS, which was validated in external datasets. Potential therapeutic targets of the MaGPS signatures were identified and confirmed by integrating spatial transcriptomics, scRNA-seq, and protein expressions. In addition, drug sensitivity analysis was performed to explore potential targeted drugs associated with MaGPS.</p><p><strong>Results: </strong>The results demonstrated the identification of a specific tumor epithelial cell cluster, c0. This cluster expressed 17 membrane-associated genes that are closely interconnected and play roles in extracellular interactions. The MaGPS model, developed based on the membrane-associated genes <i>LMO7</i>, <i>APOL1</i>, <i>SLC2A1</i>, <i>C15orf48</i>, <i>FXYD3</i>, and <i>CLDN18</i>, effectively predicted patient prognostic risk. Additionally, the expression of the six MaGPS signatures was observed to be elevated in tumors at both the protein expression and spatial transcriptomics levels. Furthermore, drug sensitivity analysis revealed that the MaGPS signature scores were significantly associated with the sensitivity to 38 different drugs, highlighting potential targeted therapies related to MaGPS.</p><p><strong>Conclusion: </strong>The MaGPS model, based on bulk RNA-seq, scRNA-seq, and spatial transcriptomics data, effectively evaluated the prognosis of pancreatic cancer and provided valuable insights for better therapeutic targets.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 4","pages":"e42791"},"PeriodicalIF":3.4,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integration of the SECI model and ChatGPT in higher education.","authors":"Urpi Barreto, Yasser Abarca","doi":"10.1016/j.heliyon.2025.e42814","DOIUrl":"10.1016/j.heliyon.2025.e42814","url":null,"abstract":"<p><p>In educational settings, the socialization, externalization, combination, and internalization (SECI) model promotes collaboration, the creation of new knowledge, and the integration of individual and collective experiences, thereby enriching learning with greater depth and meaning. The objective of this study was to identify the factors that contribute to the optimal development of the SECI model through the use of ChatGPT, to understand their interaction. The experiment included undergraduate students of business sciences at public and private universities in Cusco, Huancayo, and Lima, Peru. The students were divided into control and experimental groups, with 100 students in each group. The main selection criteria were prior knowledge of and willingness to use ChatGPT and being enrolled in a finance course. The phases of the SECI model were evaluated using ChatGPT in the experimental group through group discussions, brainstorming sessions, the creation of a manual, and individual assessments, exploring the impact of ChatGPT usage on learning. A comparison and description of each phase was conducted. Results revealed that while the use of ChatGPT improved the quality of interaction and externalization of knowledge in the experimental group compared to the control group, it did not have a notable impact on the quality of combination or internalization of knowledge. A multinomial logistic regression analyzed the impact of ChatGPT usage in each phase. Findings showed that the SECI model without ChatGPT explained 63.4 % of the change in internalization, while with ChatGPT it was 41.3 %. A positive correlation was observed between the use of ChatGPT and the performance in objective tests during the externalization and combination phases. However, while it enhanced the generation of ideas in the early stages of learning, it did not necessarily increase tacit knowledge in the internalization phase. The importance of using tools such as ChatGPT carefully and selectively, especially in the context of acquiring specialized knowledge, was emphasized.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 4","pages":"e42814"},"PeriodicalIF":3.4,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between magnesium depletion score and Klotho levels among U.S. adults: Findings from NHANES 2007-2016.","authors":"Xiaoyi Ma, Yuxin Yang, Kemin Yan, Lei Su, Jin Li, Yingying Gong, Wen He","doi":"10.1016/j.heliyon.2025.e42809","DOIUrl":"10.1016/j.heliyon.2025.e42809","url":null,"abstract":"<p><strong>Background: </strong>Magnesium is a vital mineral that plays a crucial role in various physiological processes, and its imbalance has been associated with many chronic aging-related diseases. Traditional assessment methods are insufficient, and the Magnesium Depletion Score (MDS) has been proposed as a significant indicator. Klotho, a transmembrane protein, is involved in aging regulation and oxidative stress modulation. Despite the shared relevance of MDS and Klotho to aging, their relationship remains unclear.</p><p><strong>Aims: </strong>This study aims to investigate the relationship between MDS and Klotho levels in U.S. adults.</p><p><strong>Methods: </strong>We performed a cross-sectional analysis utilizing information from the NHANES database (2007-2016), including 8285 participants. MDS was computed according to specific criteria, encompassing alcohol intake, proton pump inhibitor utilization, diuretic utilization, and renal function. Participants were categorized into groups according to MDS score: none to low (score = 0 or 1), medium (score = 2), and high (score >2). The association between MDS and Klotho levels was assessed using weighted multivariable linear regression models and subgroup analysis.</p><p><strong>Results: </strong>The analysis revealed a negative association between MDS and serum Klotho levels after comprehensive adjustment. Participants with the highest MDS showed decreased Klotho concentrations compared to those with the lowest level. This association remained robust even after excluding outliers. Subgroup analysis indicated a stronger correlation between MDS and serum Klotho concentration in individuals aged 40-60 years, women, and those with normal weight.</p><p><strong>Conclusion: </strong>The findings suggest a negative association between MDS and Klotho levels, indicating that magnesium metabolism may influence Klotho expression. These results underscore the potential significance of magnesium in aging processes and age-related diseases, highlighting the potential benefit of increasing serum Klotho concentration through magnesium supplementation.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 4","pages":"e42809"},"PeriodicalIF":3.4,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11894308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebrovascular events induced by venomous snake bites: A systematic review.","authors":"Jorge Vasconez-Gonzalez, Karen Delgado-Moreira, Juan S Izquierdo-Condoy, María de Lourdes Noboa-Lasso, Esteban Gamez-Rivera, María Belén Lopez-Molina, Andrés López-Cortés, Andrea Tello-De-la-Torre, Alejandra Torres Cerda, Daniela Silva Martinod, Esteban Ortiz-Prado","doi":"10.1016/j.heliyon.2025.e42779","DOIUrl":"10.1016/j.heliyon.2025.e42779","url":null,"abstract":"<p><p>Snake bites represent a critical public health issue, affecting approximately 2.7 million people globally each year. Around 20 % of snake species are venomous, and their venom contains a complex array of toxins that can cause multi-organ damage, particularly affecting the nervous system, leading to both ischemic and hemorrhagic cerebrovascular events. This systematic review aims to compile and analyze data on cerebrovascular events associated with venomous snakebites. A comprehensive literature search was conducted using Scopus, PubMed, SciELO, and LILACS databases, with search terms including (\"snake bite\" OR \"viper bite\") AND (\"stroke\" OR \"hemorrhagic stroke\" OR \"ischemic stroke\"). Studies in English, Spanish, French and Portuguese were reviewed, yielding 52 eligible articles reporting 73 cases of stroke following snakebites. Most cases were attributed to snakes from the <i>Viperidae</i> family, with 67.12 % of cases occurring in males. Ischemic strokes were the most frequent, comprising 73.97 % of reported cases. The most affected systems were the nervous, cardiovascular, and respiratory systems. Snakes from the <i>Bothrops</i> genera and <i>Daboia russelii</i> specie caused the widest range of symptoms, including altered consciousness, ptosis, hypertension, drowsiness, aphasia, and tachycardia. Stroke is a severe complication of snakebite envenomation. Regarding treatment, the articles included emphasize the use of antivenom serum; however, they do not go into detail about the specific management of cutaneous stroke due to a snakebite, whether ischemic or hemorrhagic It is crucial to develop standardized protocols for the management of snakebite-induced strokes and to conduct further research to identify the snake species whose venom poses the highest risk for cerebrovascular complications.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 4","pages":"e42779"},"PeriodicalIF":3.4,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11904508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification and phylogenetic analysis of marine sponges in the Jordanian Gulf of Aqaba using DNA barcoding.","authors":"Zeinab Arabeyyat, Mais Sweiss, Abdalmajeed Alajlouni, Neda'a Al-Ajlouni, Marwan Mahmoud, Sura Shartooh, Farah Alsoqi, Maysoon Kteifan","doi":"10.1016/j.heliyon.2025.e42771","DOIUrl":"10.1016/j.heliyon.2025.e42771","url":null,"abstract":"<p><p>Sponges (Porifera) are the largest biomass component of coral reefs benthic fauna among marine organisms and are very morphologically diverse. In the present work, we aimed to identify marine sponges in the Jordanian Gulf of Aqaba using the partial 18S rRNA and the 28S rRNA genes as DNA barcoding markers. A total of nine morphologically different marine sponge samples from 6.6m to approximately 22m depth were collected. Sponge fragments were frozen at -80 °C prior to DNA extraction. The sponge's DNA was extracted using a commercial kit and subjected directly to PCR amplification for the 18S rRNA and 28S rRNA genes. The DNA sequences were analyzed using the Basic Local Alignment Search Tool (BLAST) to determine the sponge's identity, and phylogenetic trees were constructed to clarify the relationship among the samples. The results obtained revealed the presence of the following genera: <i>Axinella</i>, <i>Negombata</i>, <i>Siphonochalina</i>, <i>Diacarnus</i>, and an unidentified genus within the order <i>Haplosclerida</i>. Identification of sponge species was difficult due to the scarcity of diagnostic morphological characters. To our knowledge, this is the first study in the Jordanian Gulf of Aqaba that focuses on the morphological and molecular taxonomy of marine sponges using DNA barcoding markers.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 4","pages":"e42771"},"PeriodicalIF":3.4,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11889570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DROP app: A hydroclimate information service to deliver scientific rainfall, local rainfall, and soil moisture forecasts for agricultural decision-making.","authors":"Samuel Jonson Sutanto, Spyridon Paparrizos, Lisanne Nauta, Iwan Supit, Victoria Lefèvre, Gordana Kranjac-Berisavljevic, Bizoola Zinzoola Gandaa, Richard Dogbey, Baba Mohammadu Jamaldeen, Fulco Ludwig","doi":"10.1016/j.heliyon.2025.e42740","DOIUrl":"10.1016/j.heliyon.2025.e42740","url":null,"abstract":"<p><p>Weather and Climate Information Services developed for agriculture often only provide scientific weather and climate forecasts on various timescales. Yet, local forecasts derived from indigenous knowledge and soil moisture information are still missing. In this study, we evaluate the implementation of the DROP app, a hydroclimate information service, offering both local (LF) and scientific rainfall forecasts (SF) and soil moisture forecasts, that was designed with and for smallholder farmers working on rainfed agriculture in northern Ghana. Results of the forecast assessment show that the LF generates a high probability of rain detection (POD), with a minimum value of 0.7. The hybrid forecast (HF) that integrates the SF and LF yields the highest POD value of 0.9 compared to others. However, the hybrid system also has a high number of false alarms which results in an overall lower forecast performance of HF compared to SF. Using forecasts obtained from the app, farmers adjusted their farming activities, such as time of sowing, planting and weeding dates, fertilizer and herbicide application, and harvesting. Although some limitations exist, the DROP app has potential to deliver actionable knowledge for climate-smart farm decision-making and thus, facilitate effective agriculture management.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 4","pages":"e42740"},"PeriodicalIF":3.4,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11883362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine learning to predict urine culture antibiotic sensitivities in the emergency department.","authors":"Johnathan M Sheele, Ronna L Campbell, Derick D Jones","doi":"10.1016/j.heliyon.2025.e42737","DOIUrl":"10.1016/j.heliyon.2025.e42737","url":null,"abstract":"<p><strong>Background: </strong>Urinary tract infections (UTIs) are among the most common bacterial infections diagnosed in the emergency department. Treatment of UTIs is largely empiric because urine culture results are not rapidly available.</p><p><strong>Objectives: </strong>We examined whether machine learning could predict antibiotic sensitivities of the urine cultures by using only data available during the clinical encounter.</p><p><strong>Methods: </strong>We used extreme gradient boosting (XGBoost) to examine 62,963 emergency department patient encounters from January 1, 2017, through December 31, 2021. All encounters included a urinalysis and urine culture. We included 1303 variables in the full model and examined 21 antibiotics. An antibiotic was characterized as <i>sensitive</i> only if all bacteria in the culture were susceptible; if ≥ 1 bacteria was not susceptible, then it was characterized as <i>intermediate or resistant</i>.</p><p><strong>Results: </strong>We predicted urine cultures to be sensitive vs intermediate or resistant with area under the receiver operating curve (AUROC) values ranging from 70 % (for amikacin) to 90 % (for linezolid) (median, 82 %) when negative urine cultures were characterized as antibiotic susceptible. AUROCs were as follows: nitrofurantoin (84 %); trimethoprim + sulfamethoxazole (80 %); ciprofloxacin (85 %); levofloxacin (85 %); first-generation cephalosporins (84 %); and third-generation cephalosporins (80 %). When models excluded urine cultures with no bacterial growth, AUROCs ranged from 66 % (for ampicillin) to 87 % (for amikacin) (median, 74 %). When models included only patients diagnosed with a UTI plus bacteriuria (≥10,000 colony-forming units per mL in urine culture), AUROCs ranged from 63 % (for ampicillin) to 85 % (for tetracycline) (median, 74 %).</p><p><strong>Conclusion: </strong>XGBoost can predict bacteriuria antibiotic sensitivities.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 4","pages":"e42737"},"PeriodicalIF":3.4,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11894297/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibacterial properties of bimetallic nanopattern induced by excimer laser on PTFE nanotextile.","authors":"Petr Slepička, Tereza Vašinová, Bára Frýdlová, Anna Kutová, Šárka Havlíčková, Václav Švorčík, Nikola Slepičková Kasálková","doi":"10.1016/j.heliyon.2025.e42775","DOIUrl":"10.1016/j.heliyon.2025.e42775","url":null,"abstract":"<p><p>The construction of functional micro- or nanostructured surfaces is extensively studied since they are able to provide multifunctional properties and for large variety of potential applications in fields such as tissue engineering, wearable electronics or microfluidics. The micro- or nanosized surfaces can be easily prepared by various lithography techniques, also additional modifications (laser exposure, metal deposition and further processing) and which can induce new applicable properties on the basis of synergic effect by combining aforementioned approaches. In this work we have focused on the polytetrafluoroethylene (PTFE) nanotextile with specific bimetallic nanostructures. Our primary target was to find optimal surface modification of silver/gold coated surface, which would induce strong antibacterial response to both gram-positive and/or gram-negative bacteria. We have used plasma-modified polytetrafluoroethylene nanotextile as a substrate, onto which silver and gold nanolayers were deposited by sputtering. The foils were further subjected to \"single-shot\" exposure to an excimer KrF laser and some samples were also thermally stressed before exposure. Such surfaces were further examined in terms of surface morphology and chemical composition. The surface was investigated for antibacterial properties. Their antimicrobial activity was examined <i>in vitro</i> against the bacteria <i>Escherichia coli</i> and <i>Staphylococcus epidermidis</i> strains. The surface of the prepared materials was replicated into a lactic acid polymer and the properties were again investigated in terms of surface morphology and surface chemistry. The results demonstrated construction of antibacterial surfaces with excellent resistance to bacteria <i>E. coli</i> for bimetallic structures on PTFE. Excimer laser induced bimetallic pattern exhibited also significant antibacterial properties for <i>S. epidermidis</i>. Replication of bimetallic pattern was also demonstrated.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"11 4","pages":"e42775"},"PeriodicalIF":3.4,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11904575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}