Gynecological Endocrinology最新文献_第2页

Low serum hepcidin levels in women with polycystic ovary syndrome: evidence from meta-analysis. 多囊卵巢综合征妇女血清血红素水平低：来自荟萃分析的证据。

IF 2 4区医学

Gynecological Endocrinology Pub Date : 2024-12-01 Epub Date: 2024-07-08 DOI: 10.1080/09513590.2024.2375568

Jieou Nong, Hua Li, Yunfei Yang, Qiujie Lu, Yifan Sun, Qi Yin, Hongying He

{"title":"Low serum hepcidin levels in women with polycystic ovary syndrome: evidence from meta-analysis.","authors":"Jieou Nong, Hua Li, Yunfei Yang, Qiujie Lu, Yifan Sun, Qi Yin, Hongying He","doi":"10.1080/09513590.2024.2375568","DOIUrl":"10.1080/09513590.2024.2375568","url":null,"abstract":"Background: Iron metabolism plays a significant role in the development of metabolic disorders in women with polycystic ovary syndrome (PCOS). Despite the importance of hepcidin, a key iron regulator, current research on serum hepcidin levels in PCOS patients shows conflicting results.Methods: PubMed, Embase, Web of Science, Cochrane Library and the China National Knowledge Infrastructure (CNKI) database were systematically searched from their inception to 9 September 2023. The search aimed to identify studies in English and Chinese that examined hepcidin levels in women with PCOS compared to healthy control subjects. Standardized mean differences (SMDs) with corresponding 95% confidence intervals (95% CIs) were calculated to evaluate the difference in serum hepcidin levels between women with and without PCOS.Results: The meta-analysis included a total of 10 eligible studies, which encompassed 499 PCOS patients and 391 control subjects. The pooled analysis revealed a significant reduction in serum hepcidin levels among the PCOS patients compared to the healthy controls (SMD = -3.49, 95% CI: -4.68 to -2.30, p < .05). There was no statistically significant difference in serum hepcidin levels between PCOS patients with a body mass index (BMI) < 25 and those with a BMI ≥ 25 (p > .05).Conclusion: The serum hepcidin levels of women with PCOS were significantly lower than those of healthy controls, which suggests that serum hepcidin could be a potential biomarker for PCOS.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141558650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy and safety of visnadine in the treatment of symptoms of sexual dysfunction in heterosexual women: a systematic review of randomized clinical trials. 维那丁治疗异性恋女性性功能障碍症状的有效性和安全性：随机临床试验的系统回顾。

IF 2 4区医学

Gynecological Endocrinology Pub Date : 2024-12-01 Epub Date: 2024-03-25 DOI: 10.1080/09513590.2024.2328619

Brenda Caira-Chuquineyra, Daniel Fernandez-Guzmán, Humberto Garayar-Peceros, Vicente A Benites-Zapata, Faustino R Pérez-López, Juan E Blümel, Edward Mezones-Holguín

{"title":"Efficacy and safety of visnadine in the treatment of symptoms of sexual dysfunction in heterosexual women: a systematic review of randomized clinical trials.","authors":"Brenda Caira-Chuquineyra, Daniel Fernandez-Guzmán, Humberto Garayar-Peceros, Vicente A Benites-Zapata, Faustino R Pérez-López, Juan E Blümel, Edward Mezones-Holguín","doi":"10.1080/09513590.2024.2328619","DOIUrl":"10.1080/09513590.2024.2328619","url":null,"abstract":"Objective: To synthesize the primary evidence on the efficacy and safety of visnadine on symptoms of sexual dysfunction (SD) in heterosexual women.Methods: We conducted a systematic review of randomized clinical trials (RCTs) with a primary search without language restriction in PubMed/Medline, Scopus, Embase, Web of Science, Cochrane Library, and international clinical trial registries. Trials reporting the use of visnadine by any route in women with SD were eligible. We performed screening, data extraction, and risk of bias assessment in a double-blind approach. The primary outcomes were the Female Sexual Function Index (FSFI) and its domains. Secondary outcomes were safety, arousal, lubrication, pleasure, orgasm, negative sensations, duration, and overall satisfaction.Results: Initially, 242 records were retrieved. We selected nine papers for full-text reading and finally included two RCTs: one with a parallel design and one with a crossover design with a total of 96 patients. One study compared visnadine aerosol with a placebo, while the other compared different frequencies of visnadine aerosol use. Visnadine use showed a statistically significant improvement (p < 0.05) in overall FSFI scores, regardless of the frequency of use. A meta-analysis was not possible due to the high clinical and methodological heterogeneity between available studies.Conclusion: RCTs regarding the use of visnadine for the Female SD are scarce and methodologically limited. This preliminary evidence shows visnadine as a potentially effective and safe option to alleviate some of the clinical symptoms of SD in heterosexual women. However, future better-designed randomized studies with larger sample numbers are required.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140287375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychological stressors involved in the pathogenesis of premature ovarian insufficiency and potential intervention measures. 卵巢早衰发病机制中的心理压力因素及潜在干预措施。

IF 2 4区医学

Gynecological Endocrinology Pub Date : 2024-12-01 Epub Date: 2024-05-30 DOI: 10.1080/09513590.2024.2360085

Ying-Pei Xu, Ji-Chun Fu, Zhi-Lin Hong, De-Fei Zeng, Chao-Qin Guo, Ping Li, Jin-Xiang Wu

引用次数: 0

Time-efficient consultation hours in the department of gynecological endocrinology. 妇科内分泌科的高效问诊时间。

IF 2 4区医学

Gynecological Endocrinology Pub Date : 2024-12-01 Epub Date: 2024-09-01 DOI: 10.1080/09513590.2024.2396628

Anne-Sophie Berger, Marina Sourouni, Norman Bitterlich, Kerstin Blickenstorfer, Kai J Bühling, Irene Lambrinoudaki, Xiangyan Ruan, Katrin Schaudig, Michael von Wolff, Petra Stute

{"title":"Time-efficient consultation hours in the department of gynecological endocrinology.","authors":"Anne-Sophie Berger, Marina Sourouni, Norman Bitterlich, Kerstin Blickenstorfer, Kai J Bühling, Irene Lambrinoudaki, Xiangyan Ruan, Katrin Schaudig, Michael von Wolff, Petra Stute","doi":"10.1080/09513590.2024.2396628","DOIUrl":"10.1080/09513590.2024.2396628","url":null,"abstract":"Background: The aim was to conduct a benchmark pilot study to find the best practice for consultation hours in the field of gynecological endocrinology. Suitable benchmarking participants were found in China, Germany, Greece, and Switzerland. Specifically, the study aimed to find the most time-efficient and beneficial consultation type in gynecological endocrinology focused on menopause and whether a shorter face-to-face consultation correlates with lower patient satisfaction.Methods: This was an observational study. To analyze the processes of all benchmarking participants three tools were used: a measurement of time needed for the different consultation types, a questionnaire for patients and one for physicians. The primary endpoint was the time measurement of first consultations. Secondary endpoints were the time measurements of follow-up consultations and phone consultations and patient satisfaction.Results: The mean overall duration of a first consultation differed from 20.4 min to 39.7 min (p = 0.003), mainly based on differences of the mean time to acquire the patient history, 5.6 to 21.6 min (p < 0.001). The percentage of patients who felt they had enough time to discuss questions ranged from 70% to 100% (p < 0.001). The percentage of patients who felt fully understood by their physician ranged from 62.5% to 92% (p = 0.006). The duration of a first consultation did not correlate with patients feeling well consulted (r=-0.048, p = 0.557).Conclusions: A concise patient history that concentrates on the most relevant points can reduce the total consultation time. Reducing consultation time can be made without compromising how well patients feel consulted.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142106747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of body mass index and polycystic ovary syndrome (PCOS) subtypes on periodontal health in Chinese women with PCOS and periodontitis. 体质指数和多囊卵巢综合征（PCOS）亚型对患有多囊卵巢综合征和牙周炎的中国女性牙周健康的影响。

IF 2 4区医学

Gynecological Endocrinology Pub Date : 2024-12-01 Epub Date: 2024-09-21 DOI: 10.1080/09513590.2024.2405097

Xiaodan Liu, Fengran Wang, Xiao Wang, Qingxian Luan

{"title":"Impact of body mass index and polycystic ovary syndrome (PCOS) subtypes on periodontal health in Chinese women with PCOS and periodontitis.","authors":"Xiaodan Liu, Fengran Wang, Xiao Wang, Qingxian Luan","doi":"10.1080/09513590.2024.2405097","DOIUrl":"10.1080/09513590.2024.2405097","url":null,"abstract":"Background: This study aimed to investigate the impact of body mass index (BMI) and Polycystic Ovary Syndrome (PCOS) subtypes on periodontal parameters in Chinese women with PCOS and periodontitis.Method: We conducted a retrospective case-control study analyzing data from 88 women with PCOS and 82 healthy controls. Participants were categorized by BMI (<24.0 kg/m2and ≥24.0 kg/m2) and PCOS subtypes. We compared periodontal parameters [including probing depth (PD), gingival bleeding index (GBI)] and reproductive hormone-related parameters.Results: Women with PCOS and periodontitis had a significantly higher GBI (2.71 ± 0.53) compared to controls (2.25 ± 0.41, p < 0.0001). Among patients with BMI <24.0 kg/m2, those with PCOS had a younger age [25.00(5.00) vs. 26.00(6.00) years, p < 0.05], lower PD [3.24(0.55) mm vs. 3.43 (0.48) mm, p < 0.01], and higher GBI [2.63(0.76) vs. 2.23(0.55), p < 0.0001]. For BMI ≥24.0 kg/m2, PCOS patients had a higher GBI [2.91(0.36) vs. 2.38(0.59), p < 0.01] but a lower percentage of severe periodontal disease (p < 0.05).Conclusion: PCOS could potentially worsen gingival inflammation among women already suffering from periodontitis, and a higher BMI might further intensify this correlation.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142284448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Statement of Retraction: Can Metformin reduce the incidence of Gestational Diabetes Mellitus in pregnant women with polycystic ovary syndrome? Prospective Cohort Study. 撤回声明：二甲双胍能降低多囊卵巢综合征孕妇的妊娠糖尿病发病率吗？前瞻性队列研究。

IF 2 4区医学

Gynecological Endocrinology Pub Date : 2024-12-01 Epub Date: 2024-09-23 DOI: 10.1080/09513590.2024.2401196

引用次数: 0

Expression of Concern: Laparoscopic ovarian drilling versus GnRH antagonist combined with cabergoline as a prophylaxis against the re-development of ovarian hyperstimulation syndrome. 表达关切：腹腔镜卵巢钻孔术与 GnRH 拮抗剂联合卡麦角林作为预防卵巢过度刺激综合征再次发生的方法。

IF 2 4区医学

Gynecological Endocrinology Pub Date : 2024-12-01 Epub Date: 2024-03-11 DOI: 10.1080/09513590.2024.2307189

引用次数: 0

Statement of Retraction: Luteal support with vaginal dydrogesterone increases pregnancy rate in patients with clomifene resistant polycystic ovary syndrome receiving letrozole for ovulation induction. 撤回声明：使用阴道地屈孕酮进行黄体支持可提高接受来曲唑促排卵的克罗米芬耐药多囊卵巢综合征患者的妊娠率。

IF 2 4区医学

Gynecological Endocrinology Pub Date : 2024-12-01 Epub Date: 2024-07-26 DOI: 10.1080/09513590.2024.2381309

引用次数: 0

Statement of Retraction: Oral carnitine supplementation influences mental health parameters and biomarkers of oxidative stress in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. 撤回声明：口服肉碱可影响多囊卵巢综合征妇女的精神健康参数和氧化应激生物标志物：一项随机、双盲、安慰剂对照试验。

IF 2 4区医学

Gynecological Endocrinology Pub Date : 2024-12-01 Epub Date: 2024-07-13 DOI: 10.1080/09513590.2024.2373613

引用次数: 0

Association of dietary glycemic index and glycemic load with the risk of gestational diabetes mellitus: a systematic review and dose-response meta-analysis. 膳食血糖指数和血糖负荷与妊娠糖尿病风险的关系：系统回顾和剂量反应荟萃分析。

IF 2 4区医学

Gynecological Endocrinology Pub Date : 2024-12-01 Epub Date: 2024-07-08 DOI: 10.1080/09513590.2024.2375564

Yu Zhang, Huanrong Feng, Xuefeng Li, Qiong Chen, Ruyue Shao, Chengli Wang, Yimeng Gao

{"title":"Association of dietary glycemic index and glycemic load with the risk of gestational diabetes mellitus: a systematic review and dose-response meta-analysis.","authors":"Yu Zhang, Huanrong Feng, Xuefeng Li, Qiong Chen, Ruyue Shao, Chengli Wang, Yimeng Gao","doi":"10.1080/09513590.2024.2375564","DOIUrl":"10.1080/09513590.2024.2375564","url":null,"abstract":"Objective: To comprehensively assess the dose-response association between dietary glycemic index (GI) and glycemic load (GL) and gestational diabetes mellitus (GDM) risk.Methods: PubMed, Embase, Cochrane Library, Web of Science, CNKI, WanFang, and VIP databases were searched up to May 29, 2024. Studies with at least three exposure categories were included. Dose-response analysis was also performed when covariates were adjusted in the included studies.Results: Thirteen studies involving 39,720 pregnant women were included. A linear relationship was found between GI and the risk of GDM (χ2 = 4.77, Pnon-linearity = .0923). However, association was not significant (χ2 = 0.06, p = .8000). For every unit increase in GI (range 0-30), GDM risk increased by 0.29%. After adjusting for covariates, the linear relationship persisted (χ2 = 4.95, Pnon-linearity = .084) with no significant association (χ2 = 0.08, p = .7775). For GL, a linear relationship was also found (χ2 = 4.17, Pnon-linearity =.1245), but GL was not significantly associated with GDM risk (χ2 = 2.63, p = .1049). The risk of GDM increased by 0.63% per unit increase in GL. After covariate adjustment, a significant association was observed (χ2 = 6.28, p = .0122).Conclusion: No significant association between GI and GDM risk was found. After adjusting for covariates, GL shows a significant association with GDM risk. Our findings emphasize the importance of considering dietary GL in managing the risk of GDM. Future research should continue to explore these relationships with standardized diagnostic criteria and robust adjustment for potential confounders.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141558649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0