Gynecological Endocrinology最新文献_第10页

Evaluation of the safety profile of prolonged-release EE/DNG oral contraceptives: a critical appraisal. 长效EE/DNG口服避孕药安全性评价：一项关键性评价。

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2025-12-31 Epub Date: 2025-10-21 DOI: 10.1080/09513590.2025.2571648

Jonathan Douxfils, Laure Morimont, Nina Flerin, Ulysse Gaspard, Jean-Michel Foidart

{"title":"Evaluation of the safety profile of prolonged-release EE/DNG oral contraceptives: a critical appraisal.","authors":"Jonathan Douxfils, Laure Morimont, Nina Flerin, Ulysse Gaspard, Jean-Michel Foidart","doi":"10.1080/09513590.2025.2571648","DOIUrl":"https://doi.org/10.1080/09513590.2025.2571648","url":null,"abstract":"Recent publications have suggested that a novel prolonged-release formulation of ethinylestradiol (EE) 20 µg and dienogest (DNG) 2 mg offers improved bleeding profiles and minimal impact on coagulation. These conclusions, however, are based on incomplete safety assessments and potentially misleading pharmacokinetic assumptions. This critical appraisal highlights several concerns: (1) discrepancies between published and regulatory data on bleeding/spotting rates compared to established EE/DRSP combinations; (2) inappropriate reliance on clotting-time-based activated protein C resistance (APCr) assays that fail to detect contraceptive-induced hypercoagulability; and (3) a strikingly high incidence of venous thromboembolism (VTE) reported in clinical trials of prolonged-release EE/DNG, significantly exceeding rates associated with both traditional EE-based and newer body-identical estrogen-containing contraceptives. Furthermore, these VTE cases are not transparently discussed in the peer-reviewed literature, raising ethical concerns about selective reporting. The pharmacokinetic profile of this formulation does not appear to mitigate estrogenic hepatic effects in a clinically meaningful way. Robust evaluation using validated thrombin generation assays such as the endogenous thrombin potential (ETP)-based APCr test, alongside independent post-marketing studies, is essential before asserting a neutral or favorable safety profile. Until then, claims regarding improved safety remain unsubstantiated.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"41 1","pages":"2571648"},"PeriodicalIF":1.7,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145336587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combined myo-inositol and Banaba (1% Corosolic Acid) improve HOMA-IR and hepatic insulin extraction index in overweight and obese postmenopausal women. 联合肌醇和香蕉（1%可可果酸）改善超重和肥胖绝经后妇女HOMA-IR和肝脏胰岛素提取指数。

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2025-12-31 Epub Date: 2025-12-03 DOI: 10.1080/09513590.2025.2596417

Christian Battipaglia, Valeria Vescovi, Martina Foschi, Benedetta Righi, Alessandra Sponzilli, Veronica Setti, Maria Laura Rusce, Alessandro D Genazzani

{"title":"Combined myo-inositol and Banaba (1% Corosolic Acid) improve HOMA-IR and hepatic insulin extraction index in overweight and obese postmenopausal women.","authors":"Christian Battipaglia, Valeria Vescovi, Martina Foschi, Benedetta Righi, Alessandra Sponzilli, Veronica Setti, Maria Laura Rusce, Alessandro D Genazzani","doi":"10.1080/09513590.2025.2596417","DOIUrl":"10.1080/09513590.2025.2596417","url":null,"abstract":"Objective: To assess the effects of a 12-week combined treatment with myo-inositol (2 g) and Banaba extract (48 mg) standardized to 1% corosolic acid (MBN) on insulin resistance (HOMA-IR) and hepatic insulin extraction index (HIEI) in overweight and obese postmenopausal women.Methods: We conducted a retrospective observational study including 31 postmenopausal women (mean age 51 ± 1.2 years) attending the Gynecological Endocrinology Center of Modena, Italy. All patients received daily supplementation with MBN for 12 weeks. Hormonal and metabolic parameters-including fasting glucose, insulin, C-peptide, and HOMA-IR-were assessed before and after treatment. In addition, an oral glucose tolerance test (OGTT) was performed at both time points, with glucose, insulin, and C-peptide curves measured and corresponding area under the curve (AUC) values at 240 minutes calculated. HIEI was calculated as the insulin/C-peptide ratio. Data were analyzed globally and then stratified by family history of diabetes.Results: After treatment, fasting insulin, HOMA-IR, and HIEI were significantly reduced. The OGTT showed a 23.5% decrease in glucose AUC, with greater reductions in insulin AUC (-42%) compared to C-peptide AUC (-16.8%), suggesting enhanced hepatic insulin clearance. Patients with a family history of diabetes showed reductions in insulin and C-peptide, while those without showed only a decrease in insulin and HIE, with no changes in C-peptide.Conclusions: Combined MBN supplementation improved insulin sensitivity and hepatic insulin clearance in overweight and obese postmenopausal women, with particularly pronounced effects in those with a family history of diabetes. These findings underscore the potential of targeted integrative strategies to mitigate insulin resistance in this population.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"41 1","pages":"2596417"},"PeriodicalIF":1.7,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145668272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between dietary antioxidant intakes and female infertility: evidence from the national health and nutrition examination survey 2013-2020. 膳食抗氧化剂摄入量与女性不孕症的关系：来自2013-2020年全国健康与营养检查调查的证据

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2025-12-31 Epub Date: 2025-11-30 DOI: 10.1080/09513590.2025.2590871

Haiqin Luo, TuJuan Lao, JianLing Yang, XinYuan Gao, Jie Yang, ShiWu Wen, Daniel Krewski, Weisheng Gu, Ri-Hua Xie

{"title":"Association between dietary antioxidant intakes and female infertility: evidence from the national health and nutrition examination survey 2013-2020.","authors":"Haiqin Luo, TuJuan Lao, JianLing Yang, XinYuan Gao, Jie Yang, ShiWu Wen, Daniel Krewski, Weisheng Gu, Ri-Hua Xie","doi":"10.1080/09513590.2025.2590871","DOIUrl":"https://doi.org/10.1080/09513590.2025.2590871","url":null,"abstract":"Background: Approximately one in eight women aged 15-49 years seek medical care for infertility. Oxidative stress is a critical factor in female infertility. The Composite Dietary Antioxidant Index (CDAI) is a novel metric for assessing overall dietary antioxidant capacity. This study aimed to investigate the association between CDAI, its individual components, and infertility risk.Methods: A cross-sectional analysis was conducted using 2013-2020 National Health and Nutrition Examination Survey (NHANES) data. The CDAI was calculated based on dietary intake of vitamins A, C, E, zinc, selenium, and carotenoids. Weighted logistic regression models were used to assess associations between CDAI (and its components) and infertility. Restricted cubic spline (RCS) analysis was applied to evaluate potential non-linear relationships. Subgroup and sensitivity analyses were performed to test the robustness of the findings.Results: A negative association between CDAI and infertility was observed (OR = 0.95; 95%CI [0.91-0.99], P = 0.014). Stratification by CDAI quartiles showed a consistent decreasing trend in infertility risk (Q4 vs. Q1: OR = 0.52; 95%CI [0.33-0.84], P for trend = 0.003). RCS analysis indicated a linear negative relationship between CDAI and infertility (P for non-linear = 0.278). Higher carotenoid intake was inversely associated with infertility risk, whereas intakes of vitamin A and C showed V-shaped, non-linear associations with infertility (P for non-linear < 0.05). These findings remained stable across subgroup and sensitivity analyses.Conclusion: CDAI is linearly and inversely associated with the prevalence of female infertility, highlighting the potential importance of antioxidant-rich diets in promoting women's reproductive health.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"41 1","pages":"2590871"},"PeriodicalIF":1.7,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145648401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Meta-analysis of the effects of semaglutide on body mass index (BMI) and blood lipid levels in polycystic ovary syndrome patients. 西马鲁肽对多囊卵巢综合征患者体重指数（BMI）和血脂水平影响的meta分析。

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2025-12-31 Epub Date: 2025-09-17 DOI: 10.1080/09513590.2025.2553052

Wansu Chen, Dan Xu, Xueting Shao, Qingxia Song, Renshou Chen

{"title":"Meta-analysis of the effects of semaglutide on body mass index (BMI) and blood lipid levels in polycystic ovary syndrome patients.","authors":"Wansu Chen, Dan Xu, Xueting Shao, Qingxia Song, Renshou Chen","doi":"10.1080/09513590.2025.2553052","DOIUrl":"10.1080/09513590.2025.2553052","url":null,"abstract":"Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic disorder in reproductive-aged women, often associated with obesity and dyslipidemia. Semaglutide, a GLP-1 receptor agonist (GLP-1 RA), improves glycemic control and weight, but its effects on PCOS remain unclear. This meta-analysis evaluates semaglutide's impact on BMI and blood lipids in PCOS patients. We searched PubMed, Embase, Cochrane Library, ClinicalTrials.gov, WHO ICTRP, and gray literature sources for RCTs (2010-2025) comparing semaglutide vs. placebo/conventional treatment in PCOS patients. The outcomes included BMI, total cholesterol (TC), triglycerides (TG), LDL-C, and HDL-C. The data were analyzed using RevMan 5.4, with mean differences (MD) and 95% CIs were calculated. Heterogeneity was assessed via I². Eight RCTs (526 patients) were included. Semaglutide significantly reduced BMI (MD: -2.20 kg/m², 95% CI: -2.42 to -1.97, P < 0.001), TC (MD: -0.42 mmol/L, 95% CI: -0.46 to -0.39, P < 0.0001), TG (MD: -0.35 mmol/L, 95% CI: -0.38 to -0.32, P < 0.0001), and LDL-C (MD: -0.31 mmol/L, 95% CI: -0.35 to -0.27, P < 0.0001), but not HDL-C (P = 0.8524). Subgroup analysis showed greater efficacy at doses ≥ 1.0 mg/week and in patients with a baseline BMI > 28 kg/m². Overall evidence quality was moderate to low based on GRADE assessment. Semaglutide significantly improves BMI and lipid profiles in PCOS, particularly at higher doses, and in obese patients. Further long-term studies are needed to confirm safety and reproductive outcomes.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"41 1","pages":"2553052"},"PeriodicalIF":1.7,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145080555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors influencing the occurrence of pre-eclampsia and the establishment of a risk prediction model: a retrospective study. 子痫前期发生的影响因素及风险预测模型的建立：回顾性研究。

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2025-12-31 Epub Date: 2025-10-28 DOI: 10.1080/09513590.2025.2574870

Zhenhui Wang, Yiping You, Liu Jun, Xuyin Long, Xiu Zeng

{"title":"Factors influencing the occurrence of pre-eclampsia and the establishment of a risk prediction model: a retrospective study.","authors":"Zhenhui Wang, Yiping You, Liu Jun, Xuyin Long, Xiu Zeng","doi":"10.1080/09513590.2025.2574870","DOIUrl":"https://doi.org/10.1080/09513590.2025.2574870","url":null,"abstract":"Purpose: Pre-eclampsia (PE) is a pregnancy-related disorder for which reliable predictive methods remain limited.Methods: Data were collected between June 2018 and December 2022. Statistical analyses including Chi-square tests, multivariate logistic regression, and LASSO regression were applied to identify risk factors.Results: A total of 602 pregnant women were included, with 176 diagnosed with PE and 426 without PE. Significant differences between the PE and control groups were observed for high-risk pregnancy history (HRPH), mean arterial pressure (MAP), preeclampsia monitoring system (MP), uterine artery pulsatility index (UtA-PI), placental growth factor (PLGF), thyroid-stimulating hormone (TSH), and 25-hydroxyvitamin D (25-OH). Multivariate logistic regression showed that low 25-OH (OR = 10.24, p < 0.001), elevated TSH (OR = 5.13, p < 0.001), HRPH (OR = 2.21, p = 0.03), high-risk MP (OR = 1.83, p = 0.03), UtA-PI > 2.25 (OR = 2.95, p < 0.001), and low PLGF (OR = 2.67, p < 0.001) were significantly associated with PE, while high MAP showed a non-significant trend (OR = 3.06, p = 0.06). ROC analysis indicated that 25-OH had the highest diagnostic efficiency (AUC = 0.719), MAP the lowest (AUC = 0.601), and the combination of 25-OH, TSH, MP, and PLGF achieved the best performance (AUC = 0.843).Conclusion: The combination of HRPH, MAP, PLGF, TSH, and 25-OH demonstrated strong predictive power for PE, providing valuable guidance for the prevention and management of PE in clinical practice.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"41 1","pages":"2574870"},"PeriodicalIF":1.7,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145376782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Why are there so many different estrogens in clinical practice? 为什么在临床实践中有这么多不同的雌激素？

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2025-12-31 Epub Date: 2025-11-11 DOI: 10.1080/09513590.2025.2578174

Frederick N Naftolin, Tommaso Simoncini, Peter Chedraui

引用次数: 0

Association between VDR Apa I polymorphism and subclinical hypothyroidism in patients with polycystic ovary syndrome: a pilot study. VDR Apa I多态性与多囊卵巢综合征患者亚临床甲状腺功能减退的相关性：一项初步研究

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2025-12-31 Epub Date: 2025-10-06 DOI: 10.1080/09513590.2025.2566341

Li Liu, Huixian Kang, Xuli Li, Hairong Yao, Dongmei Shi, Yongjie Liu

{"title":"Association between VDR Apa I polymorphism and subclinical hypothyroidism in patients with polycystic ovary syndrome: a pilot study.","authors":"Li Liu, Huixian Kang, Xuli Li, Hairong Yao, Dongmei Shi, Yongjie Liu","doi":"10.1080/09513590.2025.2566341","DOIUrl":"10.1080/09513590.2025.2566341","url":null,"abstract":"Purpose: To investigate the association between vitamin D receptor (VDR) gene polymorphisms and sub-clinical hypothyroidism (SCH) risk in polycystic ovary syndrome (PCOS) patients.Methods: Forty-four PCOS patients and 24 controls were enrolled. VDR gene sequences, lipid profiles, and thyroid function were analyzed, with stratification by SCH status for group comparisons.Results: PCOS patients showed significant differences in fasting glucose, triglycerides, and BMI vs. controls. SCH patients exhibited distinct Apa I genotypes (P < 0.05), with the AC genotype rate (76.47%) significantly higher in PCOS + SCH vs. other groups. Unadjusted/adjusted ORs for SCH patients with the AC genotype were 4.2 (95% CI 1.40-13.10), 5.01 (95% CI 1.53-16.38), and 6.25 (95% CI 1.69-23.09). No other polymorphisms were significant.Conclusion: This study revealed that the VDR Apa I genotype (AC as a distinct risk factor) was associated with SCH in PCOS patients, suggesting new genetic insights.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"41 1","pages":"2566341"},"PeriodicalIF":1.7,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Implantation in single euploid embryo transfers: the role of blastocyst expansion grade and early serum β-hCG levels. 单整倍体胚胎移植的着床：囊胚膨胀等级和早期血清β-hCG水平的作用。

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2025-12-31 Epub Date: 2025-10-21 DOI: 10.1080/09513590.2025.2568572

Arthur C Arcaz, Carlos Hernandez-Nieto, Joseph A Lee, Tanmoy Mukherjee, Alan B Copperman

{"title":"Implantation in single euploid embryo transfers: the role of blastocyst expansion grade and early serum β-hCG levels.","authors":"Arthur C Arcaz, Carlos Hernandez-Nieto, Joseph A Lee, Tanmoy Mukherjee, Alan B Copperman","doi":"10.1080/09513590.2025.2568572","DOIUrl":"https://doi.org/10.1080/09513590.2025.2568572","url":null,"abstract":"Objective: Is there an association between blastocyst expansion grade and early serum β-hCG levels in pregnancies after single euploid embryo transfer?Methods: This retrospective cohort study included 8394 SEETs performed at a single center. Blastocysts were categorized as CHBs (n = 1677) or PHBs (n = 4612) based on their expansion grade. Serum β-hCG levels were measured on days 9 and 11 post-transfer. A multivariate logistic regression model adjusted for confounders, including maternal age, ovarian reserve, embryo morphology, year of treatment, and day of biopsy.On day 9 post-transfer, the median β-hCG level was significantly lower in CHBs (118 mIU/mL, IQR = 129.2) compared to PHBs (133 mIU/mL, IQR = 129.8; p < 0.0001). The difference persisted on day 11 post-transfer (CHBs: 290.2 mIU/mL, IQR = 357 vs. PHBs: 327.3 mIU/mL, IQR 358.6; p = 0.018). In multivariate regression, CHB status remained significantly associated with lower β-hCG on day 9 post-transfer (aOR = 0.998, 95% CI: 0.997-0.999), but not on day 11 post-transfer (aOR = 0.999, 95% CI: 0.999-1.0002).Conclusions: Completely hatched blastocysts (CHBs) with an expansion grade 6 were associated with lower early serum β-hCG levels compared to partially hatched blastocysts (PHBs) with expansion grades 4 and 5. Incorporating expansion grade into prediction models could enhance decision support tools for IVF patients.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"41 1","pages":"2568572"},"PeriodicalIF":1.7,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145336647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Twenty years to see the obvious…. 二十年见明摆着的....

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2025-12-31 Epub Date: 2025-12-12 DOI: 10.1080/09513590.2025.2598907

Tommaso Simoncini

引用次数: 0

Glucose-dependent insulinotropic peptide (GIP) suppresses androgen biosynthesis in PCOS mouse models and cellular systems. 葡萄糖依赖性胰岛素肽（GIP）抑制多囊卵巢综合征小鼠模型和细胞系统中的雄激素生物合成。

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2025-12-31 Epub Date: 2025-11-17 DOI: 10.1080/09513590.2025.2582506

Mengru Pan, Yifan Qian, Linlin Jiang, Chunwei Cao, Lin Li

{"title":"Glucose-dependent insulinotropic peptide (GIP) suppresses androgen biosynthesis in PCOS mouse models and cellular systems.","authors":"Mengru Pan, Yifan Qian, Linlin Jiang, Chunwei Cao, Lin Li","doi":"10.1080/09513590.2025.2582506","DOIUrl":"https://doi.org/10.1080/09513590.2025.2582506","url":null,"abstract":"Objective: To assess the potential therapeutic effects of glucose-dependent insulinotropic peptide (GIP) on hyperandrogenism.Methods: Polycystic ovary syndrome (PCOS) mouse models induced by dehydroepiandrosterone (DHEA) were established to evaluate the impact of GIP on androgen synthesis in vivo. Additionally, NCI-H295R cells were utilized for in vitro studies to investigate the effects of GIP on androgen synthesis using various techniques, including CCK8, flow cytometry, RT‒qPCR, WB, ELISA, and RNA sequencing (RNA-seq).Results: Administration of GIP significantly reduced testosterone secretion in a DHEA-induced PCOS mouse model. Consistent with these findings, GIP treatment decreased testosterone release and downregulated the expression of GIP receptor (GIPR), steroidogenic acute regulatory protein (STAR), cytochrome P450 family 11 subfamily A member 1 (CYP11A1), and cytochrome P450 family 17 subfamily A member 1 (CYP17A1) in NCI-H295R cells. Notably, RNA-seq revealed that PSENEN was the most significantly downregulated gene upon GIP stimulation. Knockdown of PSENEN in NCI-H295R cells further decreased testosterone levels in the culture medium, confirming the inhibitory effect of GIP on androgen synthesis.Conclusions: Our study demonstrated that the administration of GIP reduces androgen synthesis in PCOS mouse models and at the cellular level, suggesting its potential as a novel therapeutic target for managing PCOS.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"41 1","pages":"2582506"},"PeriodicalIF":1.7,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145540017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0