Gynecological Endocrinology最新文献

Drawbacks in dopaminergic neurotransmission: compromising sexual performance. 多巴胺能神经传递的缺点：影响性行为。

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-04-24 DOI: 10.1080/09513590.2026.2662695

Anastasia Armeni, Rossella E Nappi, Peter Chedraui

引用次数: 0

Retraction statement: effects of the position of fibroids on fertility. 子宫肌瘤位置对生育能力的影响。

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-04-19 DOI: 10.1080/09513590.2026.2661492

引用次数: 0

Expression of Concern: Insulin Sensitiser Agents Alone and in Co-Treatment with r-FSH for Ovulation Induction in PCOS Women. 关注的表达：胰岛素增敏剂单独使用和与r-FSH联合治疗多囊卵巢综合征妇女促排卵。

IF 3 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-06-16 DOI: 10.1080/09513590.2026.2687275

引用次数: 0

Multidimensional health evaluation in mid-aged women: cross-sectional study protocol for a future-implementable program. 中年妇女多维健康评估：未来可实施项目的横断面研究方案

IF 3 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-03-18 DOI: 10.1080/09513590.2026.2645743

Peter Chedraui, Melissa Sánchez-Briones, Marcela Mendoza-Burgos, María C Monteverde-Álvarez, Camilo R Nevárez-Gilbert, Ricardo Echeverría-Castro, Tiziana Fidecicchi, Tommaso Simoncini

{"title":"Multidimensional health evaluation in mid-aged women: cross-sectional study protocol for a future-implementable program.","authors":"Peter Chedraui, Melissa Sánchez-Briones, Marcela Mendoza-Burgos, María C Monteverde-Álvarez, Camilo R Nevárez-Gilbert, Ricardo Echeverría-Castro, Tiziana Fidecicchi, Tommaso Simoncini","doi":"10.1080/09513590.2026.2645743","DOIUrl":"10.1080/09513590.2026.2645743","url":null,"abstract":"Objective: To conduct a comprehensive assessment of physical, functional, emotional, cognitive, nutritional, metabolic, and sexual health in mid-aged women.Methods: This cross-sectional study was conducted at the Universidad Espíritu Santo Clinic (UEES Clinic), Ecuador, as part of a multidisciplinary integrated health initiative. Women aged 40-60 years were recruited through social media outreach by the UEES Research Center and Clinic between 1 October 2024 and 1 October 2025. Interested participants scheduled a clinical evaluation by telephone. Assessments included laboratory tests (complete blood count, FSH, estradiol, HDL-C, triglycerides, glucose, and thyroid hormones [T3, T4]); validated surveys: Menopause Rating Scale (MRS) for climacteric symptoms and quality of life; Center for Epidemiologic Studies Depression Scale, 10-item version (CESD-10) for depressive mood; short Everyday Memory Questionnaire-Revised (EMQ-R) for cognition; and FSFI-6 for sexual function. Participants also underwent anthropometric measurements, body composition analysis, muscle strength testing, and dietary assessment.Discussion: This methods paper describes a multidisciplinary approach for the comprehensive health evaluation of mid-aged women. It enables early identification of factors affecting quality of life and provides a replicable framework relevant to both local and broader Latin American contexts, serving as a model for similar initiatives across the region.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"42 1","pages":"2645743"},"PeriodicalIF":3.0,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147473214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reproductive transitions and autoimmunity: implications for women's health in rheumatology and gastroenterology. 生殖过渡和自身免疫：对风湿病和胃肠病学妇女健康的影响。

IF 3 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-03-17 DOI: 10.1080/09513590.2026.2645835

Lorenzo Cavagna, Marco Vincenzo Lenti, Laura Cucinella, Francesca Bottazzi, Antonio Di Sabatino, Rossella E Nappi

{"title":"Reproductive transitions and autoimmunity: implications for women's health in rheumatology and gastroenterology.","authors":"Lorenzo Cavagna, Marco Vincenzo Lenti, Laura Cucinella, Francesca Bottazzi, Antonio Di Sabatino, Rossella E Nappi","doi":"10.1080/09513590.2026.2645835","DOIUrl":"10.1080/09513590.2026.2645835","url":null,"abstract":"Women's reproductive life encompasses dynamic phases, including menarche, menstrual cycles, pregnancy, lactation, and menopause, as well as transitional periods of variable duration. These stages drive physiological changes that influence both physical and mental well-being and may modulate susceptibility to autoimmunity. The interplay between autoimmunity and reproductive milestones is bidirectional: reproductive stages can affect disease onset and progression, while autoimmune disorders influence fertility, pregnancy outcomes, and the timing of menopause. Persistent challenges in detecting autoimmune diseases, particularly within rheumatology and gastroenterology, underscore the need for targeted screening, multidisciplinary collaboration, and patient-centered strategies. Fertility preservation, preconception counseling, and individualized pregnancy management are essential to safeguard reproductive rights and optimize maternal and neonatal outcomes. Post-reproductive life, especially the menopause transition, represents a vulnerable period in which immune, hormonal, and metabolic changes converge. This manuscript highlights the importance of a comprehensive, lifespan-oriented approach to reproductive well-being in women with autoimmune diseases, integrating preventive, diagnostic, and therapeutic strategies across all stages of reproduction.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"42 1","pages":"2645835"},"PeriodicalIF":3.0,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147467692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microbiota and adenomyosis: exploring mechanisms and therapeutic potential. 微生物群和子宫腺肌症：探索机制和治疗潜力。

IF 3 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-04-16 DOI: 10.1080/09513590.2026.2660983

Qi Zhang, Lili Zou, Hongbo Yu, Junjie Wang

{"title":"Microbiota and adenomyosis: exploring mechanisms and therapeutic potential.","authors":"Qi Zhang, Lili Zou, Hongbo Yu, Junjie Wang","doi":"10.1080/09513590.2026.2660983","DOIUrl":"10.1080/09513590.2026.2660983","url":null,"abstract":"Objective: This review comprehensively explores the potential relationship between the microbiota and adenomyosis, aiming to identify specific microbial biomarkers, elucidate the molecular mechanisms underlying the involvement of the microbiota in the disease, and provide insights into more precise and personalized therapeutic strategies for patients with adenomyosis.Methods: This article adopts the narrative review method to comprehensively analyze the literature on the relationship between the microbiota and adenomyosis. A comprehensive literature search was conducted in PubMed, Embase and Web of Science databases. A total of 8 articles were included, among which one was an animal experiment. This review focuses on analyzing the differences in the composition of the microbiota between patients with adenomyosis and healthy control groups, as well as the potential molecular mechanisms by which the microbiota participates in the development of adenomyosis.Results: Studies have demonstrated that the composition of the microbiota in women with adenomyosis differs significantly from that in healthy controls.The potential mechanisms by which microbiota may be involved in adenomyosis are closely associated with immune-inflammatory responses and estrogen regulation, which further affect the progression of adenomyosis.Conclusions: Microbiota may play an important role in the pathogenesis of adenomyosis. Elucidating the specific microbial biomarkers and the underlying molecular mechanisms of microbiota in adenomyosis is crucial for developing novel, precise, and personalized therapeutic strategies, which may provide new options for the treatment of adenomyosis.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"42 1","pages":"2660983"},"PeriodicalIF":3.0,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147698672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Melatonin modulates granulosa cell angiogenesis differently in female- and male-factor infertility. 褪黑素在女性和男性因素不育中对颗粒细胞血管生成的调节不同。

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2025-12-23 DOI: 10.1080/09513590.2025.2606440

Giovanna Santos Cavalcanti, Kátia Cândido Carvalho, Pedro Augusto Araujo Monteleone, Peter Chedraui, José Cipolla-Neto, Joji Ueno, Ricardo Hsieh, Eduardo Carvalho de Arruda Veiga, Edmund Chada Baracat, José Maria Soares

{"title":"Melatonin modulates granulosa cell angiogenesis differently in female- and male-factor infertility.","authors":"Giovanna Santos Cavalcanti, Kátia Cândido Carvalho, Pedro Augusto Araujo Monteleone, Peter Chedraui, José Cipolla-Neto, Joji Ueno, Ricardo Hsieh, Eduardo Carvalho de Arruda Veiga, Edmund Chada Baracat, José Maria Soares","doi":"10.1080/09513590.2025.2606440","DOIUrl":"https://doi.org/10.1080/09513590.2025.2606440","url":null,"abstract":"Objective: To analyze the effects of melatonin on angiogenesis in cultured granulosa cells from women undergoing in vitro fertilization, comparing those with female-factor versus male-factor infertility.Methods: Granulosa cells were obtained from 47 women undergoing in vitro fertilization treatment, including 31 women with female-factor (FFG) and 16 women with male-factor infertility (MFG). Cells from both groups were cultured and divided into four treatment conditions for 96 h: a) control (culture medium without melatonin); b) vehicle (melatonin diluent-ethanol); c) 0.1 µM melatonin; and d) 10 µM melatonin. Expression of 84 genes involved in angiogenesis signaling pathway was analyzed by real-time PCR.Results: Cultured granulosa cells from both groups expressed aromatase and melatonin receptors. In both groups, cell proliferation peaked at 72 h when exposed to 10 µM melatonin. Of the 84 analyzed genes, three showed significant differential mRNA expression. In the MFG, melatonin at 10 µM upregulated VEGF-B mRNA expression in granulosa cells but downregulated PDGFA and HGF mRNA expression, in contrast to the higher expression of these genes in the FFG under identical conditions.Conclusion: Melatonin differentially modulates angiogenesis-related gene expression in granulosa cells, indicating that its effects may depend on infertility type and melatonin dose in women undergoing in vitro fertilization.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"42 1","pages":"2606440"},"PeriodicalIF":1.7,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145809796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Iatrogenic menopause and long-term health: a call for better evidence. 医源性更年期与长期健康：呼吁提供更好的证据。

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-04-08 DOI: 10.1080/09513590.2026.2656080

Ipek Betul Ozcivit Erkan, Punith Kempegowda

引用次数: 0

From 'polycystic ovary syndrome' to 'polyendocrine metabolic ovarian syndrome': why terminology matters. 从“多囊卵巢综合征”到“卵巢多内分泌代谢综合征”：为什么术语很重要。

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-06-02 DOI: 10.1080/09513590.2026.2680750

Peter Chedraui, Rossella E Nappi

引用次数: 0

European society of gynecology (ESG) position paper on the proposed terminology change from PCOS to PMOS. 欧洲妇科学会（ESG）关于建议将PCOS术语改为PMOS的立场文件。

IF 3 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-06-29 DOI: 10.1080/09513590.2026.2695512

Camil Castelo-Branco, Svetlana Vujovic, Alessandro D Genazzani, Mark Brincat, Blazej Meczekalski, Petra Stute, Andrea R Genazzani, Geraldine Brichant, Raoul Orvieto, Ineta Vasaraudze, Tevfik Yoldemir, Angelos Daniilidis

{"title":"European society of gynecology (ESG) position paper on the proposed terminology change from PCOS to PMOS.","authors":"Camil Castelo-Branco, Svetlana Vujovic, Alessandro D Genazzani, Mark Brincat, Blazej Meczekalski, Petra Stute, Andrea R Genazzani, Geraldine Brichant, Raoul Orvieto, Ineta Vasaraudze, Tevfik Yoldemir, Angelos Daniilidis","doi":"10.1080/09513590.2026.2695512","DOIUrl":"10.1080/09513590.2026.2695512","url":null,"abstract":"Background: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder whose terminology inadequately reflects its systemic nature. The proposed renaming to polyendocrine metabolic ovary syndrome (PMOS) aims to better represent its pathophysiology.Objective: To present the European Society of Gynaecology (ESG) position regarding the proposed terminology change and its implementation.Methods: Expert consensus and narrative synthesis of current scientific evidence and international recommendations.Results: ESG supports a structured, patient-centered transition strategy. Recommendations include prioritizing patient communication, implementing a gradual transition with prolonged dual terminology use, and integrating the new terminology systematically into scientific and educational frameworks. The importance of interdisciplinary clarity and the central role of gynecological endocrinology are emphasized.Conclusion: A phased and clearly communicated transition will enhance conceptual accuracy while preserving patient understanding, continuity of care, and clinical coordination.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"42 1","pages":"2695512"},"PeriodicalIF":3.0,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148345201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0