Gynecologic oncology最新文献

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Pre-clinical efficacy of RAF/MEK clamp avutometinib in combination with FAK inhibition for low-grade serous ovarian cancer RAF/MEK钳夹阿武托米尼联合FAK抑制剂治疗低级别浆液性卵巢癌的临床前疗效
IF 4.5 2区 医学
Gynecologic oncology Pub Date : 2024-10-09 DOI: 10.1016/j.ygyno.2024.07.058
Blair McNamara, Michelle Greenman, Cem Demirkiran, Levent Mutlu, Tobias Hartwich, Stefania Bellone, Diego Manavella, Margherita Zipponi, Yang Yang-Hartwich, Kevin Yang, Elena Ratner, Peter Schwartz, Alessandro Santin
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引用次数: 0
Spatial transcriptomics identifies unique loss of immunosurveillance in endometrial cancers of women with severe obesity 空间转录组学发现重度肥胖妇女的子宫内膜癌丧失了独特的免疫监视功能
IF 4.5 2区 医学
Gynecologic oncology Pub Date : 2024-10-09 DOI: 10.1016/j.ygyno.2024.07.031
Estefania Fernandez , Brenda Melendez , Richard Yang , Rossana Lazcano Segura , Mikayla Bowen , Khalida Wani , Bhavana Singh , Joseph Celestino , Laurence Bernard , Tri Nguyen , Alexander Lazar , Jennifer Wargo , Karen Lu , Melinda Yates
{"title":"Spatial transcriptomics identifies unique loss of immunosurveillance in endometrial cancers of women with severe obesity","authors":"Estefania Fernandez , Brenda Melendez , Richard Yang , Rossana Lazcano Segura , Mikayla Bowen , Khalida Wani , Bhavana Singh , Joseph Celestino , Laurence Bernard , Tri Nguyen , Alexander Lazar , Jennifer Wargo , Karen Lu , Melinda Yates","doi":"10.1016/j.ygyno.2024.07.031","DOIUrl":"10.1016/j.ygyno.2024.07.031","url":null,"abstract":"","PeriodicalId":12853,"journal":{"name":"Gynecologic oncology","volume":null,"pages":null},"PeriodicalIF":4.5,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142420326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dostarlimab plus chemotherapy followed by dostarlimab plus niraparib maintenance therapy among patients with primary advanced or recurrent endometrial cancer in the ENGOT-EN6-NSGO/GOG-3031/RUBY trial ENGOT-EN6-NSGO/GOG-3031/RUBY试验中的原发性晚期或复发性子宫内膜癌患者接受多斯他利单抗加化疗后再接受多斯他利单抗加尼拉帕利的维持治疗
IF 4.5 2区 医学
Gynecologic oncology Pub Date : 2024-10-09 DOI: 10.1016/j.ygyno.2024.07.016
Mansoor Mirza , Sharad Ghamande , Lars Hanker , Destin Black , Nicoline Raascou-Jensen , Lucy Gilbert , Ana Oaknin , Angeles Alvarez Secord , Antonella Savarese , Robert Holloway , Rebecca Kristeleit , Joseph Buscema , Ingrid Boere , Sudarshan Sharma , Christine Gennigens , Prafull Ghatage , Kaitlin Yablonski , Shadi Stevens , Hanna Trukhan , Matthew Powell
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引用次数: 0
Efficacy and safety of alpelisib plus olaparib versus chemotherapy among patients with platinum-resistant or refractory high-grade serous ovarian cancer without BRCA mutation: Primary analysis of the EPIK-O trial 在无 BRCA 基因突变的铂类耐药或难治性高级别浆液性卵巢癌患者中,阿来替尼联合奥拉帕利与化疗相比的疗效和安全性:EPIK-O 试验的初步分析
IF 4.5 2区 医学
Gynecologic oncology Pub Date : 2024-10-09 DOI: 10.1016/j.ygyno.2024.07.024
Panagiotis Konstantinopoulos , Jae-Weon Kim , Gilles Freyer , Jung-Yun Lee , Lydia Gaba , Rachel Grisham , Nicoletta Colombo , Xiaohua Wu , Jalid Sehouli , Felipe Cruz , David Cibula , Bradley Monk , Gitte-Bettina Nyvang , Michael Friedlander , Domenica Lorusso , Els Van Nieuwenhuysen , Rosalind Glasspool , Christian Marth , Patsy Hinson , Monica Zuradelli , Antonio González-Martín
{"title":"Efficacy and safety of alpelisib plus olaparib versus chemotherapy among patients with platinum-resistant or refractory high-grade serous ovarian cancer without BRCA mutation: Primary analysis of the EPIK-O trial","authors":"Panagiotis Konstantinopoulos , Jae-Weon Kim , Gilles Freyer , Jung-Yun Lee , Lydia Gaba , Rachel Grisham , Nicoletta Colombo , Xiaohua Wu , Jalid Sehouli , Felipe Cruz , David Cibula , Bradley Monk , Gitte-Bettina Nyvang , Michael Friedlander , Domenica Lorusso , Els Van Nieuwenhuysen , Rosalind Glasspool , Christian Marth , Patsy Hinson , Monica Zuradelli , Antonio González-Martín","doi":"10.1016/j.ygyno.2024.07.024","DOIUrl":"10.1016/j.ygyno.2024.07.024","url":null,"abstract":"","PeriodicalId":12853,"journal":{"name":"Gynecologic oncology","volume":null,"pages":null},"PeriodicalIF":4.5,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142420841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Financial toxicity in gynecologic oncology and its impact on medication access, debt, and food insecurity 妇科肿瘤的财务毒性及其对药物获取、债务和粮食不安全的影响
IF 4.5 2区 医学
Gynecologic oncology Pub Date : 2024-10-09 DOI: 10.1016/j.ygyno.2024.07.081
Alana Lanser, Bunja Rungruang, Sharad Ghamande, Robert Higgins, Marian Johnson, David Mysona
{"title":"Financial toxicity in gynecologic oncology and its impact on medication access, debt, and food insecurity","authors":"Alana Lanser, Bunja Rungruang, Sharad Ghamande, Robert Higgins, Marian Johnson, David Mysona","doi":"10.1016/j.ygyno.2024.07.081","DOIUrl":"10.1016/j.ygyno.2024.07.081","url":null,"abstract":"","PeriodicalId":12853,"journal":{"name":"Gynecologic oncology","volume":null,"pages":null},"PeriodicalIF":4.5,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142416286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk of cancer progression of non-atypical endometrial hyperplasia in a diverse patient population: A long-term, follow-up study 不同患者群体中的非典型子宫内膜增生症癌变风险:长期随访研究
IF 4.5 2区 医学
Gynecologic oncology Pub Date : 2024-10-09 DOI: 10.1016/j.ygyno.2024.07.102
Benjamin Yao, Ken Lin, Sara Isani, Pe-er Dar, Ohad Rotenberg
{"title":"Risk of cancer progression of non-atypical endometrial hyperplasia in a diverse patient population: A long-term, follow-up study","authors":"Benjamin Yao, Ken Lin, Sara Isani, Pe-er Dar, Ohad Rotenberg","doi":"10.1016/j.ygyno.2024.07.102","DOIUrl":"10.1016/j.ygyno.2024.07.102","url":null,"abstract":"","PeriodicalId":12853,"journal":{"name":"Gynecologic oncology","volume":null,"pages":null},"PeriodicalIF":4.5,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142420272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early phase vs. late phase clinical trials: Trends in enrollment of racial and ethnic minority groups 早期与晚期临床试验:少数种族和族裔群体的入组趋势
IF 4.5 2区 医学
Gynecologic oncology Pub Date : 2024-10-09 DOI: 10.1016/j.ygyno.2024.07.104
Michael Richardson , Danika Barry , Jecca Steinberg , Kai Holder , Vineeth Thirunavu , Danielle Strom , Naixin Zhang , Brandon Turner , Christopher Magnani , Brannon Weeks , Anna Marie Young , Connie Lu , Tierney Wolgemuth , Nora Laasiri , Natalie Squires , Jill Anderson , Beth Karlan , John Chan , Daniel Kapp , Dario Roque , Ritu Salani
{"title":"Early phase vs. late phase clinical trials: Trends in enrollment of racial and ethnic minority groups","authors":"Michael Richardson , Danika Barry , Jecca Steinberg , Kai Holder , Vineeth Thirunavu , Danielle Strom , Naixin Zhang , Brandon Turner , Christopher Magnani , Brannon Weeks , Anna Marie Young , Connie Lu , Tierney Wolgemuth , Nora Laasiri , Natalie Squires , Jill Anderson , Beth Karlan , John Chan , Daniel Kapp , Dario Roque , Ritu Salani","doi":"10.1016/j.ygyno.2024.07.104","DOIUrl":"10.1016/j.ygyno.2024.07.104","url":null,"abstract":"","PeriodicalId":12853,"journal":{"name":"Gynecologic oncology","volume":null,"pages":null},"PeriodicalIF":4.5,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142420274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of sintilimab plus bevacizumab in recurrent/persistent ovarian clear cell carcinoma (INOVA): A multicenter, single-arm, phase II trial 辛替利单抗加贝伐单抗治疗复发性/顽固性卵巢透明细胞癌的疗效(INOVA):多中心、单臂、II 期试验
IF 4.5 2区 医学
Gynecologic oncology Pub Date : 2024-10-09 DOI: 10.1016/j.ygyno.2024.07.059
Qinglei Gao , Xingyu Liu , Bairong Xia , Wei Zhang , Li Sun , Cui Feng , Yi Huang , Yunong Gao , Jie Jiang , Guiling Li , Yu Zhang
{"title":"Efficacy of sintilimab plus bevacizumab in recurrent/persistent ovarian clear cell carcinoma (INOVA): A multicenter, single-arm, phase II trial","authors":"Qinglei Gao , Xingyu Liu , Bairong Xia , Wei Zhang , Li Sun , Cui Feng , Yi Huang , Yunong Gao , Jie Jiang , Guiling Li , Yu Zhang","doi":"10.1016/j.ygyno.2024.07.059","DOIUrl":"10.1016/j.ygyno.2024.07.059","url":null,"abstract":"","PeriodicalId":12853,"journal":{"name":"Gynecologic oncology","volume":null,"pages":null},"PeriodicalIF":4.5,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142416061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monitoring minimal residual disease using circulating tumor DNA in patients treated long-term with PARP inhibitors for ovarian cancer 利用循环肿瘤 DNA 监测长期接受 PARP 抑制剂治疗的卵巢癌患者的极小残留病灶
IF 4.5 2区 医学
Gynecologic oncology Pub Date : 2024-10-09 DOI: 10.1016/j.ygyno.2024.07.055
Dahye Lee, Yoo-Na Kim, Dongju Won, Jung-Yun Lee
{"title":"Monitoring minimal residual disease using circulating tumor DNA in patients treated long-term with PARP inhibitors for ovarian cancer","authors":"Dahye Lee, Yoo-Na Kim, Dongju Won, Jung-Yun Lee","doi":"10.1016/j.ygyno.2024.07.055","DOIUrl":"10.1016/j.ygyno.2024.07.055","url":null,"abstract":"","PeriodicalId":12853,"journal":{"name":"Gynecologic oncology","volume":null,"pages":null},"PeriodicalIF":4.5,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142416722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Too much of a good thing? Projecting the need for gynecologic oncologists over the next 20 years 好事太多?预测未来 20 年对妇科肿瘤专家的需求
IF 4.5 2区 医学
Gynecologic oncology Pub Date : 2024-10-09 DOI: 10.1016/j.ygyno.2024.07.050
Teresa Boitano , Evan Myers , Laura Havrilesky , Stephanie Blank , Warner Huh
{"title":"Too much of a good thing? Projecting the need for gynecologic oncologists over the next 20 years","authors":"Teresa Boitano , Evan Myers , Laura Havrilesky , Stephanie Blank , Warner Huh","doi":"10.1016/j.ygyno.2024.07.050","DOIUrl":"10.1016/j.ygyno.2024.07.050","url":null,"abstract":"","PeriodicalId":12853,"journal":{"name":"Gynecologic oncology","volume":null,"pages":null},"PeriodicalIF":4.5,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142421345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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