Gynecologic oncology最新文献_第6页

Benefit and cost: Early PARP inhibitor exposure shortens times to subsequent recurrences 收益和成本：早期暴露PARP抑制剂可缩短随后复发的时间

IF 4.1 2区医学

Gynecologic oncology Pub Date : 2026-02-01 Epub Date: 2026-02-14 DOI: 10.1016/j.ygyno.2026.01.210

Floor Backes , Anna Gonzalez , Reed O'Connor , Julia Chalif , Paulina Haight , Monica Levine , Robert Neff , Christa Nagel , Casey Cosgrove , Laura Chambers , David Cohn , Larry Copeland , David O'Malley

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Missed opportunities for ovarian cancer prevention with salpingectomy 错失了输卵管切除术预防卵巢癌的机会

IF 4.1 2区医学

Gynecologic oncology Pub Date : 2026-02-01 Epub Date: 2026-02-14 DOI: 10.1016/j.ygyno.2026.01.209

Laureen Gbordzoe, Mehrnaz Siavoshi, Christine Garcia, Allison Kay

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HPV clade classification is associated with response to chemoradiation in locally advanced cervical cancer 局部晚期宫颈癌的HPV分级与放化疗反应相关

IF 4.1 2区医学

Gynecologic oncology Pub Date : 2026-02-01 Epub Date: 2026-02-14 DOI: 10.1016/j.ygyno.2026.01.194

Shae Jansen Aref , D'Shaunique Walters , Matthew Wong , Molly El Alam , David Lo , Timothy Harris , Jhoan Sebastian Gonzalez Diaz , Travis Sims , Nadim Ajami , Lauren Colbert

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Neighborhood deprivation & oncologic outcomes in cervical cancer at a large, urban, tertiary care and NCI referral center 在大型城市三级保健和NCI转诊中心，社区剥夺与宫颈癌的肿瘤预后

IF 4.1 2区医学

Gynecologic oncology Pub Date : 2026-02-01 Epub Date: 2026-02-14 DOI: 10.1016/j.ygyno.2026.01.226

Megan Teramoto, Sarah Ackroyd, Nita Lee, Sandra Tilmon, Gini Fleming, Seiko Yamada

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Improving treatment of radiation-induced premature ovarian insufficiency after cervical cancer: A practice quality improvement initiative 改善宫颈癌后放疗性卵巢早衰的治疗：一项实践质量改善倡议

IF 4.1 2区医学

Gynecologic oncology Pub Date : 2026-02-01 Epub Date: 2026-02-14 DOI: 10.1016/j.ygyno.2026.01.224

Emily Smith , Neil Taunk , Jonathan Heintz , Arina Chesnokova

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Racial differences in endometrial stripe thickness among uterine cancer patients 子宫癌患者子宫内膜条纹厚度的种族差异

IF 4.1 2区医学

Gynecologic oncology Pub Date : 2026-02-01 Epub Date: 2026-02-14 DOI: 10.1016/j.ygyno.2026.01.223

Simone Sasse , Sarah Lawson , Sydney Williams , Arslan Kasimov , Danielle Blemur , Brooke Howitt

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A second chance for the second look: Feasibility of laparoscopic HIPEC at the conclusion of upfront treatment for epithelial ovarian cancer 第二次机会：在上皮性卵巢癌前期治疗结束时腹腔镜HIPEC的可行性

IF 4.1 2区医学

Gynecologic oncology Pub Date : 2026-02-01 Epub Date: 2026-02-14 DOI: 10.1016/j.ygyno.2026.01.213

Ana Kouri , Anya Menzies , Kristen Stearns , Christine McGough , Fang-Chi Hsu , Janelle Darby , Michael Kelly , Samuel Lentz , Laurel Berry

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TOC TOC

IF 4.1 2区医学

Gynecologic oncology Pub Date : 2026-02-01 Epub Date: 2026-02-20 DOI: 10.1016/S0090-8258(26)00797-3

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Safety and feasibility of concomitant urogynecologic and gynecologic oncology surgical procedures 泌尿妇科和妇科肿瘤外科手术的安全性和可行性。

IF 4.1 2区医学

Gynecologic oncology Pub Date : 2026-02-01 Epub Date: 2026-01-27 DOI: 10.1016/j.ygyno.2026.01.007

Kyle Wohlrab , Katina Robison , David D. Rahn , Gena C. Dunivan , John Occhino , Jon Pennycuff , Marina Frimer , Elizabeth Lokich , Kari Ring , Denise Uyar , Ira Winer , Holly E. Richter

{"title":"Safety and feasibility of concomitant urogynecologic and gynecologic oncology surgical procedures","authors":"Kyle Wohlrab , Katina Robison , David D. Rahn , Gena C. Dunivan , John Occhino , Jon Pennycuff , Marina Frimer , Elizabeth Lokich , Kari Ring , Denise Uyar , Ira Winer , Holly E. Richter","doi":"10.1016/j.ygyno.2026.01.007","DOIUrl":"10.1016/j.ygyno.2026.01.007","url":null,"abstract":"<div><div>This joint Clinical Consensus Statement on the safety and feasibility of concomitant urogynecologic and gynecologic oncology surgical procedures reflects statements drafted by content experts from the American Urogynecologic Society and the Society of Gynecologic Oncology. The writing group used a Delphi process to evaluate statements developed from a structured literature search and assessed consensus. A total of 35 statements were assessed in the following categories: (1) background, (2) treatment options, (3) timing of concurrent surgery, (4) risk factors, and (5) value-based care. Of the 35 statements, 28 reached consensus on initial review. Three statements were omitted, and 4 statements were revised and reached consensus following second review utilizing the Delphi process.</div></div><div><h3>Why this matters</h3><div>Pelvic floor disorders are common among patients with gynecologic cancer and significantly affect quality of life. Despite this significant overlap, only a minority of patients undergo concomitant urogynecologic surgical procedures at the time of surgical intervention for a gynecologic malignancy, and there is no current consensus on patient selection, timing of concurrent procedures, and best practices in the gynecologic oncology population. A critical evaluation of the current evidence surrounding the safety and feasibility of joint procedures is crucial to inform joint decision making with patients and identify knowledge gaps for future research.</div></div>","PeriodicalId":12853,"journal":{"name":"Gynecologic oncology","volume":"205 ","pages":"Pages 120-127"},"PeriodicalIF":4.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147270828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Understanding patient priorities: Sexual health and hereditary ovarian cancer syndromes 了解患者的优先事项：性健康和遗传性卵巢癌综合征

IF 4.1 2区医学

Gynecologic oncology Pub Date : 2026-02-01 Epub Date: 2026-01-30 DOI: 10.1016/j.ygyno.2025.12.010

Luiza Perez , Amita Kulkarni , Steve Lopez , Jesse T. Brewer , Xiaoyue Ma , Shoshana M. Rosenberg , Melissa K. Frey

{"title":"Understanding patient priorities: Sexual health and hereditary ovarian cancer syndromes","authors":"Luiza Perez , Amita Kulkarni , Steve Lopez , Jesse T. Brewer , Xiaoyue Ma , Shoshana M. Rosenberg , Melissa K. Frey","doi":"10.1016/j.ygyno.2025.12.010","DOIUrl":"10.1016/j.ygyno.2025.12.010","url":null,"abstract":"<div><h3>Background</h3><div>Patients with hereditary breast and ovarian cancer syndromes are frequently recommended risk-reducing salpingo-oophorectomy years before natural menopause. While effective in reducing cancer-related morbidity and mortality, salpingo-oophorectomy increases the risk of sexual dysfunction. This study explores patient experiences and perspectives on integrating sexual health support within hereditary cancer syndrome care.</div></div><div><h3>Methods</h3><div>From 02/2023–11/2023, we conducted a cross-sectional survey study at a gynecologic oncology clinic. Patients at increased genetic risk for breast and ovarian cancer completed a 26-question survey adapted from previous literature. Descriptive and univariate analyses were performed.</div></div><div><h3>Results</h3><div>Of 81 patients approached, 75 (93 %) participated. Median age was 42 years (IQR 13.5); 46 (61 %) had prior risk-reducing surgery, and 22 (29 %) had history of breast cancer. Sixty-six (88 %) reported that sexuality and intimacy were important and 57 (76 %) felt these issues should be addressed by the healthcare team. Sixty (80 %) preferred discussing sexual health with a physician. Patients welcomed discussions at multiple timepoints, including before risk-reducing surgery (46, 61 %) and during follow-up (67, 89 %). Twenty-six (35 %) felt it was too overwhelming to address sexual health at the time of pathogenic variant diagnosis. Key interests included consequences of risk-reducing treatments (58, 77 %) and strategies for maintaining sexuality and intimacy (49, 65 %).</div></div><div><h3>Conclusion</h3><div>Sexual health is a significant concern for patients with hereditary breast and ovarian cancer risk. Most prefer physician-led conversations throughout different stages of care. These findings underscore the importance of a proactive, patient-centered approach to sexual health communication in this population.</div></div>","PeriodicalId":12853,"journal":{"name":"Gynecologic oncology","volume":"205 ","pages":"Pages 113-119"},"PeriodicalIF":4.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146073947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0