Ana Tirado Escuder, María Paz Palacios Rosales, Pablo Bellot García, Cayetano Fabián Miralles Maciá
{"title":"Hepatitis colestásica paraneoplásica secundaria a linfoma de Hodgkin tratada con terapia MARS y brentuximab vedotina","authors":"Ana Tirado Escuder, María Paz Palacios Rosales, Pablo Bellot García, Cayetano Fabián Miralles Maciá","doi":"10.1016/j.gastrohep.2026.502713","DOIUrl":"10.1016/j.gastrohep.2026.502713","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 8","pages":"Article 502713"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147377119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Celis, Rodrigo Quera, Paulina Núñez, Christian von Muhlenbrock, Ricardo Espinoza, Alexandra Concha, Camila Mendoza, Francisca Marcet, Daniela Araya, Javiera Fuentes, Fernanda Riesco, Piedad Correa
{"title":"Eficacia y seguridad a largo plazo del trasplante de microbiota fecal guiado por colonoscopia en la infección recurrente por Clostridioides difficile: serie prospectiva de casos","authors":"Andrea Celis, Rodrigo Quera, Paulina Núñez, Christian von Muhlenbrock, Ricardo Espinoza, Alexandra Concha, Camila Mendoza, Francisca Marcet, Daniela Araya, Javiera Fuentes, Fernanda Riesco, Piedad Correa","doi":"10.1016/j.gastrohep.2026.502719","DOIUrl":"10.1016/j.gastrohep.2026.502719","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 8","pages":"Article 502719"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147511490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Márquez Pérez, Laura Carrión Martín, Lorena Hidalgo Aguirre, Andrés Conthe Alonso, Ana Matilla Peña
{"title":"Hepatocellular carcinoma surveillance: A practical guide based on current evidence","authors":"Laura Márquez Pérez, Laura Carrión Martín, Lorena Hidalgo Aguirre, Andrés Conthe Alonso, Ana Matilla Peña","doi":"10.1016/j.gastrohep.2026.502825","DOIUrl":"10.1016/j.gastrohep.2026.502825","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 8","pages":"Article 502825"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148338469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The impact of gluten-containing and gluten-free diets on intestinal inflammation: Evaluation of fecal calprotectin in a healthy rat model","authors":"Atilla Bektaş, Meltem Ulusoy, Ahmet Melih Özel","doi":"10.1016/j.gastrohep.2026.502711","DOIUrl":"10.1016/j.gastrohep.2026.502711","url":null,"abstract":"<div><h3>Objective</h3><div>Gluten-free diets are increasingly adopted by individuals without gluten-related disorders, despite limited evidence for anti-inflammatory benefit. We evaluated whether varying gluten exposure influences intestinal inflammation in healthy rats using fecal calprotectin (fKp) as the outcome.</div></div><div><h3>Patients and methods</h3><div>Forty newly weaned male Wistar albino rats were randomized to four isocaloric, iso-nitrogenic diets for 12 weeks (<em>n</em> <!-->=<!--> <!-->10/group): (1) standard wheat-containing control, (2) gluten-free animal protein-based diet, (3) control diet supplemented with 6% vital wheat gluten, and (4) control diet supplemented with 12% vital wheat gluten. Food and water were provided ad libitum. After a 12-h fast, rats were sacrificed and cecal fecal samples were collected individually. fKp was measured using an enzyme-linked immunosorbent assay (ELISA).</div></div><div><h3>Results</h3><div>Mean fKp differed across groups (one-way ANOVA, <em>p</em> <!-->=<!--> <!-->0.030). Compared with the gluten-free group (26.57<!--> <!-->±<!--> <!-->5.77<!--> <!-->μg/g), fKp was lower with 6% gluten (23.33<!--> <!-->±<!--> <!-->5.14<!--> <!-->μg/g) and 12% gluten (23.57<!--> <!-->±<!--> <!-->4.86<!--> <!-->μg/g) (<em>p</em> <!-->=<!--> <!-->0.013). fKp did not differ between the standard control (29.98<!--> <!-->±<!--> <!-->5.76<!--> <!-->μg/g) and gluten-free diets (<em>p</em> <!-->><!--> <!-->0.05). There was no difference between 6% and 12% supplementation, indicating a plateau effect.</div></div><div><h3>Conclusion</h3><div>In healthy rats, gluten-containing diets did not increase intestinal inflammation as assessed by fKp. Gluten elimination provided no anti-inflammatory advantage over a standard diet, whereas moderate gluten supplementation was associated with lower fKp without a clear dose–response. Findings should be interpreted cautiously and considered hypothesis-generating rather than definitive.</div></div>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 8","pages":"Article 502711"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147325812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María Buti, Antonio Aguilera, José Luis Calleja, José María Molero, Pablo Ryan, José Joaquín Antón, Raquel Domínguez-Hernández, Alberto de la Cuadra-Grande, Federico García
{"title":"Corrigendum de “Recomendaciones sobre el diagnóstico de pacientes con el virus de la hepatitis delta (VHD) en España [Gastroenterología y Hepatología 49 (2026) 502768]”","authors":"María Buti, Antonio Aguilera, José Luis Calleja, José María Molero, Pablo Ryan, José Joaquín Antón, Raquel Domínguez-Hernández, Alberto de la Cuadra-Grande, Federico García","doi":"10.1016/j.gastrohep.2026.502848","DOIUrl":"10.1016/j.gastrohep.2026.502848","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 8","pages":"Article 502848"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149016804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Javier P Gisbert, Javier Alcedo, Javier Amador, Jesús Barrio, Luis Bujanda, Xavier Calvet, Luis Fernández-Salazar, José María Huguet, Ángel Lanas, Alfredo J Lucendo, Samuel J Martínez-Domínguez, Leticia Moreira, Olga P Nyssen, Pablo Parra, Ángeles Pérez-Aisa, Javier Tejedor-Tejada
{"title":"VI Spanish Consensus Conference on the treatment of Helicobacter pylori infection.","authors":"Javier P Gisbert, Javier Alcedo, Javier Amador, Jesús Barrio, Luis Bujanda, Xavier Calvet, Luis Fernández-Salazar, José María Huguet, Ángel Lanas, Alfredo J Lucendo, Samuel J Martínez-Domínguez, Leticia Moreira, Olga P Nyssen, Pablo Parra, Ángeles Pérez-Aisa, Javier Tejedor-Tejada","doi":"10.1016/j.gastrohep.2026.502847","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502847","url":null,"abstract":"<p><p>Helicobacter pylori (H. pylori) infection is highly prevalent in the Spanish population and is the main cause of chronic gastritis, peptic ulcer disease, and gastric cancer. Five previous consensus meetings on the management of H. pylori infection in Spain have been held, the most recent in 2021. Changes in treatment regimens and the growing body of available evidence justified the organization of this VI Spanish Consensus Conference in June 2026, focused on the treatment of this infection. Sixteen experts in the field participated, performed a systematic literature search, and developed 25 recommendations, which were subsequently submitted to an iterative process of serial anonymous voting using Delphi methodology. The GRADE system was used to classify the certainty of the evidence and the strength of the recommendations. As a starting point, this consensus establishes that the recommended treatments should achieve, and preferably exceed, a 90% cure rate when administered empirically. Accordingly, quadruple regimens are recommended as both first-line and rescue treatments. As first-line treatment, a 10-day regimen with a proton pump inhibitor plus bismuth, tetracycline, and metronidazole (Pylera®) is recommended. After failure of this regimen, a combination of a proton pump inhibitor, amoxicillin, levofloxacin, and bismuth is recommended. This consensus also provides a detailed review of other rescue treatment alternatives.</p>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502847"},"PeriodicalIF":2.0,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149108718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An endoscopic challenge in the treatment of late dumping syndrome after Roux-en-Y gastric bypass.","authors":"Marina Vélez, Maria Pellisé, Joan Llach","doi":"10.1016/j.gastrohep.2026.502866","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502866","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502866"},"PeriodicalIF":2.0,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149108622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eider López Gaztelu, Irene Moraleja, Juan Antonio Arévalo, Ana Arechalde Pérez, Aitor Orive Calzada, Iago Rodríguez-Lago
{"title":"Porphyria in ulcerative colitis: two cases and a novel drug trigger.","authors":"Eider López Gaztelu, Irene Moraleja, Juan Antonio Arévalo, Ana Arechalde Pérez, Aitor Orive Calzada, Iago Rodríguez-Lago","doi":"10.1016/j.gastrohep.2026.502869","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502869","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502869"},"PeriodicalIF":2.0,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149108671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Javier P Gisbert, Javier Alcedo, Javier Amador, Jesús Barrio, Luis Bujanda, Xavier Calvet, Luis Fernández-Salazar, José María Huguet, Ángel Lanas, Alfredo J Lucendo, Samuel J Martínez-Domínguez, Leticia Moreira, Olga P Nyssen, Pablo Parra, Ángeles Pérez-Aisa, Javier Tejedor-Tejada
{"title":"VI Conferencia Española de Consenso sobre el tratamiento de la infección por Helicobacter pylori.","authors":"Javier P Gisbert, Javier Alcedo, Javier Amador, Jesús Barrio, Luis Bujanda, Xavier Calvet, Luis Fernández-Salazar, José María Huguet, Ángel Lanas, Alfredo J Lucendo, Samuel J Martínez-Domínguez, Leticia Moreira, Olga P Nyssen, Pablo Parra, Ángeles Pérez-Aisa, Javier Tejedor-Tejada","doi":"10.1016/j.gastrohep.2026.502847","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502847","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502847"},"PeriodicalIF":2.0,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149108732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}