Gastroenterologia y hepatologia最新文献

{"title":"TRANSLATION AND PSYCHOMETRIC EVALUATION OF THE SPANISH VERSION OF THE INFLAMMATORY BOWEL DISEASE KNOWLEDGE (IBD-KNOW) QUESTIONNAIRE.","authors":"Pilar Corsino Roche, Josep-Oriol Casanovas-Marsal, Santiago García López, Raquel Vicente Lidón, Eva Sierra Moros, Sonia Gallego Montañés, Diego Casas Deza, Laura Vicente Manso, Laura Lafarga-Molina","doi":"10.1016/j.gastrohep.2025.502576","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2025.502576","url":null,"abstract":"<p><strong>Objective: </strong>To translate, culturally adapt, and validate the Inflammatory Bowel Disease Knowledge questionnaire in adult Spanish-speaking patients with IBD.</p><p><strong>Patients and methods: </strong>A cross-sectional translation and linguistic validation study was conducted with 30 participants aged >18 years with inflammatory bowel disease at the Miguel Servet University Hospital (Zaragoza, Spain). The IBD-KNOW questionnaire was translated and culturally adapted following ISPOR guidelines. Content validity was assessed by a panel of experts using Aiken's V coefficient. Internal consistency was evaluated using Cronbach's alpha, and test-retest reliability was assessed with the intraclass correlation coefficient (ICC). Descriptive analyses and bivariate tests were used to evaluate sociodemographic and clinical variables, as well as associations with IBD knowledge.</p><p><strong>Results: </strong>The study assessed 30 adults (50% female) with an average age of 44.21±15.05 years; mean age at diagnosis 29.24±11.42 years and mean disease duration 14.97±8.70 years. The Spanish version of the IBD-KNOW demonstrated good internal consistency (Cronbach's α = 0.74) and strong test-retest reliability (ICC = 0.80; 95% CI: 0.62-0.89). No statistically significant differences were found between the test and retest scores (p = 0.39) or completion times (p = 0.736). The mean questionnaire score was 5.87 ± 1.53 out of 24.</p><p><strong>Conclusions: </strong>The Spanish version of the IBD-KNOW questionnaire is a valid, reliable, and culturally appropriate instrument for assessing disease-related knowledge in Spanish-speaking IBD patients. Its use in clinical settings can support the identification of educational needs and the design of targeted interventions aimed at improving patient engagement and health outcomes.</p>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502576"},"PeriodicalIF":1.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145039972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CLINICAL, ENDOSCOPIC AND HISTOLOGICAL CHARACTERISTICS OF CHLAMYDIA TRACHOMATIS PROCTITIS IN MALES.","authors":"Marta Teller, Antonio Giordano, Carlos González-Muñoza, Jordi Gordillo, Federico Bertoletti, Fernando Sánchez-Reus, Esther Garcia-Planella","doi":"10.1016/j.gastrohep.2025.502558","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2025.502558","url":null,"abstract":"<p><strong>Objective: </strong>Chlamydia trachomatis is a prevalent cause of infectious proctitis, often misdiagnosed as cancer or inflammatory bowel disease (IBD). This study aims to describe the main clinical symptoms, together with endoscopic and histopathological characteristics of Chlamydia trachomatis proctitis in the general population.</p><p><strong>Patients and methods: </strong>A retrospective observational study was conducted at a single institution, identifying all cases of proctitis due to Chlamydia trachomatis infection, detected by real-time PCR in rectal biopsy or anal smear, with endoscopic assessment.</p><p><strong>Results: </strong>A total of 28 male patients were included (median age 37, IQR 31-48). Among them, 20 patients reported having sex with males. Concomitant infections included HIV (n=10), Neisseria gonorrhoea (n=4), and Treponema pallidum (n=2). A history of sexually transmitted diseases was reported by 18 patients (64%). The main clinical symptoms were rectal bleeding (79%) and diarrhoea (43%). The main endoscopic findings were rectal erythema (71%) and ulcers (57%), with rectal (89%) and sigmoid inflammation (11%). In 5 cases (18%), a single isolated deep rectal ulcer was the only finding. In 16 cases (57.1%), neoplasia, IBD or fissure was suspected according to endoscopy. Histological findings included mixed inflammatory infiltrate of lamina propria (95%), cryptitis (54%), and crypt abscesses (32 %).</p><p><strong>Conclusions: </strong>Endoscopically detected Chlamydia Trachomatis proctitis in men presents with worrisome symptoms and nonspecific rectal ulcers, with chronic inflammation histology. This generates doubts about differential diagnosis with IBD and rectal cancer.</p>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502558"},"PeriodicalIF":1.9,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Territorial equity assessment within a colorectal cancer screening program: usefulness of colonoscopy quality indicators.","authors":"Rebeca Font, Anna Serradesanferm, Ramon Clèries, Judit Solà, Maria Pellisé, Francesc Balaguer, Josep M Castellví, Oscar Navarro-Campàs, Natàlia Pascual-Argente, Ester Sánchez-Tilló, Josep A Espinàs, Antoni Castells","doi":"10.1016/j.gastrohep.2025.502559","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2025.502559","url":null,"abstract":"<p><strong>Objective: </strong>The primary goal of a public health system is to ensure universal access to high-quality medical care. However, disparities in health outcomes have been observed across socio-demographic groups, some of them potentially related to their geographical location. To assess territorial equity, the Catalan Colorectal Cancer Screening Program was used, focusing on the adenoma detection rate (ADR) endoscopists.</p><p><strong>Patients and methods: </strong>This population-based screening program is based on fecal immunochemical testing. Positive individuals undergo colonoscopy in the endoscopy unit corresponding to their area of residency. Both ADR and serrated polyp detection rate (SPDR) of all endoscopists were assessed and reported in terms of variability among endoscopy units and proportion of endoscopists who did not reach pre-established quality standards (40% and 20%, respectively).</p><p><strong>Results: </strong>A total of 35,825 colonoscopies performed by 206 endoscopists of 39 endoscopy units were evaluated. Analysis of ADR variability revealed that 11 units (28.2%) performed significantly above the average of Catalonia, while 3 units (7.7%) performed below it. In terms of SPDR variability, 22 units (56.4%) significantly exceeded the average, whereas 8 units (20.5%) fell below this benchmark. Moreover, all endoscopists in 28 units (71.8%) achieved the ADR threshold of 40%, while this occurred in only 12 (30.8%) when using the SPDR threshold of 20%.</p><p><strong>Conclusion: </strong>Quality of colonoscopy, measured by the ADR, was high with minimal variability among units; however, using the SPDR revealed greater variability. This analysis underscores the value of indicators derived from screening programs as essential tools for evaluating potential territorial inequities.</p>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502559"},"PeriodicalIF":1.9,"publicationDate":"2025-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metastatic breast cancer as a cause of gastroduodenal obstruction. A matter for endoscopists.","authors":"Sara Campos Cancela, Iago Gavín Piña, Natalia García Morales, Antonio Rodríguez D'Jesús","doi":"10.1016/j.gastrohep.2025.502561","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2025.502561","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502561"},"PeriodicalIF":1.9,"publicationDate":"2025-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatigue in patients with Inflammatory Bowel Disease: a descriptive cross-sectional study.","authors":"Ana Mª López-Calleja, Beatriz López Cauce, Marisa Iborra Colomino, Beatriz Villarrubia Martín, Luis Menchén, Carmen Lobo Rodríguez","doi":"10.1016/j.gastrohep.2025.502557","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2025.502557","url":null,"abstract":"<p><strong>Aim: </strong>To identify factors associated with the presence of fatigue in patients with inflammatory bowel disease.</p><p><strong>Patients and method: </strong>Prospective cross-sectional descriptive study conducted in a multidisciplinary centre for the treatment of EIMI. Participants were patients diagnosed with IBD under follow-up in an advanced practice nurse (APN) consultation. Sociodemographic and clinical variables, biochemical parameters, disease activity, quality of life, severity of fatigue, anxiety and depression were collected. A multivariate analysis was performed with logistic regression adjusted for sex and years of disease progression.</p><p><strong>Results: </strong>A total of 243 patients were included, 174 (71.6%) with Crohn's disease and 69 (28.4%) with ulcerative colitis; 73 (30.2%) reported fatigue. Patients with fatigue had a significantly lower quality of life EuroQol-5D-5L: 60.08 vs. 76.34, (p<0.001, 95%CI: 12.15-20.36) and IBDQ-9 57.53 vs. 76.54, (p<0.001, 95%CI:15.35-22.67). The regression model adjusted for sex and years of disease included moderate disease activity (OR: 4.88, p<0.001, 95%CI: 2.13-11. 14), probable case of anxiety (OR: 2.16, p=0.031, 95% CI: 0.78-4.34), probable case of depression (OR: 2.86, p=0.004, 95%CI: 1.41-5.81).</p><p><strong>Conclusions: </strong>Fatigue was significantly associated with poorer health-related quality of life in patients with moderate disease activity and those experiencing anxiety or depression. These findings highlight the necessity of a comprehensive approach that includes early detection of fatigue and associated psychosocial factors.</p>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502557"},"PeriodicalIF":1.9,"publicationDate":"2025-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of Sociodemographic Factors, Healthy Habits, and Weight Stigma With Non-Alcoholic Fatty Liver Disease Risk in Obese Workers: Findings From a Large Occupational Cohort.","authors":"Mónica Egea Sancho, José Ignacio Ramírez-Manent, Pedro Juan Tárraga López, Irene Coll Campayo, María Teófila Vicente-Herrero, Ángel Arturo López-González","doi":"10.1016/j.gastrohep.2025.502560","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2025.502560","url":null,"abstract":"<p><strong>Background: </strong>Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global health concern, particularly among individuals with obesity. While metabolic and behavioral risk factors have been well described, the role of psychosocial determinants, such as weight stigma, remains underexplored.</p><p><strong>Objectives: </strong>To assess the association between sociodemographic variables, healthy lifestyle behaviors, and internalized weight stigma with MASLD risk in a large cohort of obese workers across Spain.</p><p><strong>Patients and methods: </strong>This cross-sectional study analyzed data from 26,816 obese employees who underwent occupational health screenings between January 2021 and December 2024. MASLD risk was assessed using three validated indices: the Fatty Liver Index (FLI), Hepatic Steatosis Index (HSI), and Lipid Accumulation Product (LAP). Sociodemographic characteristics, adherence to the Mediterranean diet, physical activity, smoking status, and weight stigma (assessed by the Weight Bias Internalization Scale) were evaluated. Multivariable logistic regression models were used to estimate associations.</p><p><strong>Results: </strong>Weight stigma was significantly associated with higher risk of MASLD across all three indices, independent of age, sex, social class, and health behaviors. Participants with internalized weight stigma were 1.6 to 2.3 times more likely to present with high-risk scores. Sociodemographic disparities and unhealthy lifestyle factors also contributed to elevated MASLD risk.</p><p><strong>Conclusions: </strong>Beyond metabolic and behavioral determinants, internalized weight stigma emerges as a strong independent factor associated with MASLD risk. These findings underscore the importance of incorporating psychosocial components into liver disease prevention strategies in occupational settings.</p>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502560"},"PeriodicalIF":1.9,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Advanced Therapies and Real-World Outcomes in Crohn's Disease: A Population-Based Comparison of Two Incident Cohorts in Navarra.","authors":"Alfonso Elosua, Óscar Nantes, María Chaparro, Lucía Zabalza, Rebeca Irisarri, Miren Vicuña, Marcos Kutz, Saioa Rubio, Julián Librero, Ramón Angós, Ana Garre, Javier P Gisbert, Cristina Rodríguez","doi":"10.1016/j.gastrohep.2025.502540","DOIUrl":"10.1016/j.gastrohep.2025.502540","url":null,"abstract":"<p><strong>Objective: </strong>The introduction of biologic therapies has transformed the management of Crohn's disease (CD), yet few studies have evaluated their impact on real-world outcomes over time. We aimed to compare two population-based cohorts of CD patients in Navarra, Spain, diagnosed in 2001-2003 (cohort A) and in 2017 (cohort B), to assess whether early use of advanced therapies has altered disease trajectory.</p><p><strong>Patients and methods: </strong>This prospective, multicentre cohort study included adult patients with confirmed CD from two periods. Clinical characteristics, treatments, hospitalizations, and surgical outcomes were analysed over five years. Time-to-event analyses were performed using Kaplan-Meier curves and Cox regression models.</p><p><strong>Results: </strong>A total of 128 patients were included (83 in cohort A, 45 in cohort B). At diagnosis, immunomodulators were used in 1.2% of cohort A vs. 21% in cohort B, and biologics in 0% vs. 51%, respectively. Initiation of immunomodulators (hazard ratio [HR]: 1.94; 95% CI: 1.11-3.39) and biologics (HR: 5.42; 95% CI: 2.57-11.42) occurred earlier in cohort B. Hospitalization at diagnosis was more frequent in cohort A (47% vs. 22%), and five-year hospitalization rates were significantly lower in cohort B (34% vs. 63%; HR: 0.52; 95% CI: 0.28-0.96). No significant differences in intestinal or perianal surgery rates were observed between cohorts.</p><p><strong>Conclusions: </strong>Earlier and more widespread use of advanced therapies in CD has been associated with reduced hospitalization over time, although surgical rates have remained stable. These findings suggest a shift toward earlier and more intensive treatment strategies in routine clinical practice.</p>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502540"},"PeriodicalIF":1.9,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Appendiceal Angiodysplasia: an unexpected cause of gastrointestinal bleeding.","authors":"Marc Lleixà Rioboo, Andrés Arango, Alexandre Rey, Ignasi Elizalde, Eva C Vaquero, Míriam Cuatrecasas, Ariadna Sánchez, María Daca-Álvarez","doi":"10.1016/j.gastrohep.2025.502538","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2025.502538","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502538"},"PeriodicalIF":1.9,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adjunctive resection of residual mucosal flap during Z-POEM for large Zenker's diverticulum.","authors":"Zhongshang Sun, Fazhen Xu, Xiaozhong Yang, Aijun Zhou, Bing Hu, Liansong Ye, Feng Pan","doi":"10.1016/j.gastrohep.2025.502537","DOIUrl":"10.1016/j.gastrohep.2025.502537","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502537"},"PeriodicalIF":1.9,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Banding-and-SINK for small (≤10-mm) gastrointestinal subepithelial tumours: A valid and effective alternative.","authors":"Joan B Gornals, Sandra Maisterra, Francesc Bas-Cutrina","doi":"10.1016/j.gastrohep.2025.502539","DOIUrl":"10.1016/j.gastrohep.2025.502539","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502539"},"PeriodicalIF":1.9,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}