Gastroenterologia y hepatologia最新文献

{"title":"Gastroesophageal Reflux Disease: How to Differentiate It from Esophageal Disorders of the Gut-Brain Interaction.","authors":"C Gómez Labrador, E Resina, F M Fernández-Gordón Sánchez, S Casabona-Francés","doi":"10.1016/j.gastrohep.2026.502915","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502915","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502915"},"PeriodicalIF":2.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Capsule retention revealing systemic follicular lymphoma with small-bowel involvement.","authors":"Carla Santos-Pascual, Ana García-Rodríguez, Natacha Llopart-Maurin, Maria Puigcerver-Mas","doi":"10.1016/j.gastrohep.2026.502918","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502918","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502918"},"PeriodicalIF":2.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolated Gastric Neurofibroma: An Exceptional Mimicker of Gastrointestinal Stromal Tumors.","authors":"Carlos Manuel Ortiz-Mendoza, Francisco Emilio Domínguez García-Diego, Marijose Abascal Morales, Paulina Jiménez Jáuregui, José Ernesto Carrera-González","doi":"10.1016/j.gastrohep.2026.502917","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502917","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502917"},"PeriodicalIF":2.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacotherapeutic safety in patients with liver cirrhosis: a national multidisciplinary survey on resources and perceived needs.","authors":"Andrea Rodriguez Esquiroz, Amaya Echeverría Gorriti, Javier Garjón Parra, Inés Aguinaga Ontoso","doi":"10.1016/j.gastrohep.2026.502916","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502916","url":null,"abstract":"<p><strong>Objective: </strong>To analyze, at a national and multidisciplinary level, the availability of resources, the level of knowledge, and the perceived needs of healthcare professionals in the management of patients with liver cirrhosis.</p><p><strong>Patients and methods: </strong>A national, multicenter, descriptive, cross-sectional study was conducted using a questionnaire aimed at medicine, pharmacy, and nursing professionals in primary care, hospital care, and community pharmacy. Professional profiles, the use of clinical decision support tools, and self-perceived training were evaluated. Qualitative variables were expressed as frequencies and percentages. To assess national variability and differences by professional profiles, Pearson's ꭓ2test or Fisher's exact test was used, as appropriate.</p><p><strong>Results: </strong>A total of 275 responses were analyzed (94% national coverage). A marked polarization in healthcare delivery and a low availability of local protocols (12.7%) were detected, with significant gaps between hospital and primary care settings. Critical deficiencies were highlighted in training (only 5.1% perceived themselves as fully trained), lack of computerized safety alerts (30.5%), and absence of patient educational materials (77.8%). There is a majority demand (91.6%) for quick-reference clinical management guidelines.</p><p><strong>Conclusions: </strong>The pharmacotherapeutic management of liver cirrhosis is limited by a critical lack of specialized training and support tools. The almost unanimous demand for resources justifies the urgent need to implement clinical decision support systems to optimize patient safety.</p>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502916"},"PeriodicalIF":2.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unexpected yellow nodules in the esophagus: when common histology becomes uncommon.","authors":"María Dolores Baños Salmerón, Ana Rosa Parra Tercero, Ángel Romo-Navarro, Carlos Vicente Hernández","doi":"10.1016/j.gastrohep.2026.502872","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502872","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502872"},"PeriodicalIF":2.0,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"OPTIMIZATION OF THE RELATIONSHIP WITH PRIMARY CARE TO MAXIMIZE THE DIAGNOSIS OF HEPATITIS B VIRUS INFECTION IN MIGRANT POPULATIONS FROM HIGH-PREVALENCE AREAS: VHBilbao PROJECT.","authors":"Pablo Ruiz, Laura Deiss, Laura Buendía, Ainara Merino, Nahia Ispizua, Saioa De La Maza, Paloma Liendo, Amaia Baranda, Fernando Menéndez, Sonia Blanco","doi":"10.1016/j.gastrohep.2026.502894","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502894","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502894"},"PeriodicalIF":2.0,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149147613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distinct Microbiological Profile of Intra-Abdominal Abscesses in Crohn's Disease: A Multicenter Cohort Study from GETECCU.","authors":"Cristina Polo Cuadro, Santiago García-López, Ana Royo Esteban, Ruth de Francisco, Milagros Vela González, Fernando Bermejo, Ignacio Blanco, Álvaro de la Serna, Luis Bujanda, Lorena Bernal, José Luis Rueda García, Carla J Gargallo-Puyuelo, Esteban Fuentes-Valenzuela, Beatriz Castro, Jordi Guardiola, Gema Ladrón, Carles Suria, Julia Sáez Fuster, Javier P Gisbert, Beatriz Sicilia, Raquel Gomez, Carmen Muñoz Vilafranca, Manuel Barreiro-de Acosta, Elena Peña, Marta Castillo Pradillo, Elena Cerrillo, Xavier Calvet, Noemí Manceñido, David Monfort I Miquel, Sandra Marín, Cristina Roig, Ainhoa Marcé Ormaza, Patricia Ramírez de Piscina, Elena Betoré, Albert Martin-Cardona, Marta Teller, Inmaculada Alonso Abreu, Nuria Maroto, Santiago Frago, Diego Gardeazabal, Isabel Pérez-Martínez, Ángel David Febles González, Sara Barrero, Carlos Taxonera, Irene García de la Filia, Ander Ezkurra-Altuna, Lucía Madero, María Dolores Martín-Arranz, Fernando Gomollón, Laura Letona Gimenez, Juan Manuel García-Lechuz Moya, Eugeni Domènech, Diego Casas Deza","doi":"10.1016/j.gastrohep.2026.502893","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502893","url":null,"abstract":"<p><strong>Objective: </strong>Intra-abdominal abscesses are a common and severe complication of penetrating Crohn's disease (CD). Data on their microbiological profile are scarce, yet essential for optimizing antibiotic strategies. The aim of our study is to analyse the differences between the pathogens found in patients with CD and in the control group, as well as their resistance rates.</p><p><strong>Patients and methods: </strong>We conducted a multicenter, observational study using data from the ENEIDA registry and a control cohort recruited at a tertiary hospital. CD patients with intra-abdominal abscesses requiring hospitalization between 2011 and 2021 were included. Controls were patients with non-CD intra-abdominal abscesses from the same timeframe.</p><p><strong>Results: </strong>A total of 145 CD patients and 156 controls were analyzed. Controls were older (58 vs 42 years, p<0.001), while sex distribution was similar. Escherichia coli was the most frequent pathogen in both cohorts. Streptococcus was more frequent in CD (29% vs. 14%, p=0.02), whereas Pseudomonas was more frequent in controls (12% vs. 1.4%, p=0.016). In the multivariate analysis, the absence of CD and pelvic abscess location were independently associated with the presence of Pseudomonas. Resistance rate was significantly higher in CD patients receiving immunosuppressive therapy (70.5% vs 50.6%, P=0.030). Antibiotic empirical regimens differed, but adequate coverage was similar (80% vs. 77%) between groups.</p><p><strong>Conclusions: </strong>CD-associated intra-abdominal abscesses display a distinct microbiological profile, with a higher prevalence of Streptococcus, whereas the prevalence of Pseudomonas is exceptional.</p>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502893"},"PeriodicalIF":2.0,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149148176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MANAGEMENT OF ANTITHROMBOTIC AGENTS PRIOR TO COLONOSCOPY: EXPERIENCE IN A SECONDARY CARE HOSPITAL.","authors":"Margarita Fernández de la Varga, Miriam Celada Sendino, Pedro Amor Martín, Carlos Ordieres Díaz, Marta Álvarez Posadilla, Adrián Huergo Fernández","doi":"10.1016/j.gastrohep.2026.502876","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502876","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502876"},"PeriodicalIF":2.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149136343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Masa pancreática heterogénea: el papel clave de la ultrasonografía endoscópica.","authors":"Paula Boyero Moreno, Daniel Barranco Castro, Carlos Ortiz Moyano, Belén Maldonado Pérez, Manuel Rodríguez-Téllez","doi":"10.1016/j.gastrohep.2026.502875","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502875","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502875"},"PeriodicalIF":2.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revisión sistemática sobre las estrategias terapéuticas en la dispepsia funcional: abordajes farmacológicos y no farmacológicos según el subtipo clínico.","authors":"Maika Aragunde Marcos, Alberto Ezquerra, Leticia Moreira, Elizabeth Barba","doi":"10.1016/j.gastrohep.2026.502870","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502870","url":null,"abstract":"<p><p>Functional dyspepsia is a disorder of gut-brain interaction that significantly affects quality of life and has a limited therapeutic response. This systematic review, conducted according to PRISMA 2020, analyzed randomized clinical trials published over the past ten years in adults meeting Rome III/IV criteria. Prokinetics showed no consistent benefit, except in some patients with overlapping subtypes. In postprandial distress syndrome, a low-FODMAP diet was not superior to conventional dietary advice, except, in a subgroup analysis, in patients with abdominal distension, while mirtazapine showed signals of benefit in patients with weight loss or early satiety. In epigastric pain syndrome, low-dose amitriptyline was superior to pantoprazole. Herbal therapies, electroacupuncture, transcutaneous auricular vagus nerve stimulation, and multidisciplinary care showed signals of benefit, mostly derived from single trials, whereas cannabidiol was ineffective. Overall, the evidence supports a personalized, stepwise, and biopsychosocial approach to treatment.</p>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502870"},"PeriodicalIF":2.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}