Judith Cortada, Francesca Castaldo, Jordi Sánchez-Delgado, José Ferrusquía-Acosta, Meritxell Casas, Mireia Miquel, Mario Sutil-Vega, Mercedes Vergara, Cristina Solé
{"title":"Prevalence and prognosis of cirrhotic cardiomyopathy in hospitalized patients with decompensated cirrhosis.","authors":"Judith Cortada, Francesca Castaldo, Jordi Sánchez-Delgado, José Ferrusquía-Acosta, Meritxell Casas, Mireia Miquel, Mario Sutil-Vega, Mercedes Vergara, Cristina Solé","doi":"10.1016/j.gastrohep.2025.502518","DOIUrl":"10.1016/j.gastrohep.2025.502518","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502518"},"PeriodicalIF":2.2,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144368788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Suárez-Saro Fernández, Mónica Barreales Valbuena, Cristina Martín-Arriscado Arroba, Elena Gómez Domínguez, Álvaro Hidalgo Romero, Inmaculada Fernández Vázquez
{"title":"Prognostic value of early Lille score in patients with severe alcohol-associated hepatitis.","authors":"Ana Suárez-Saro Fernández, Mónica Barreales Valbuena, Cristina Martín-Arriscado Arroba, Elena Gómez Domínguez, Álvaro Hidalgo Romero, Inmaculada Fernández Vázquez","doi":"10.1016/j.gastrohep.2025.502517","DOIUrl":"10.1016/j.gastrohep.2025.502517","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effectiveness of the Lille Index (LI) on day 2 (LI2) and day 4 (LI4) in predicting short-term mortality in patients with severe alcohol-associated hepatitis (SAH) and to assess its concordance compared to the Lille Index on day 7 (LI7).</p><p><strong>Patients and methods: </strong>This retrospective, observational, single-center study included SAH patients admitted between 2016 and 2023. SAH was defined as a Maddrey score ≥32 and/or a MELD score ≥21. The predictive ability of LI2, LI4, and LI7 for 28-, 90-, and 180-day mortality was analyzed using AUC, Cox regression (Hazar Ratio (HR)), and Kaplan-Meier curves.</p><p><strong>Results: </strong>Among 65 SAH patients, 62 received corticosteroids. Median follow-up was 722 days. LI2 was associated with a 28-day mortality HR of 33.1 (95% CI: 3.8-287.3), similar to LI7 (HR: 13.2; 95% CI: 2.2-81.2). AUCs for 28-day mortality were 0.818 for LI2, 0.794 for LI4, and 0.809 for LI7 (p>0.05). The proportion of patients classified by prognosis was similar for LI2 vs. LI7 (68.33% vs. 70.97%, p=0.752) and LI4 vs. LI7 (73.33% vs. 70.97%, p=0.771). Concordance between LI2 and LI7 was 85%, and between LI4 and LI7 was 93.33%.</p><p><strong>Results: </strong>Among 65 SAH patients, 62 received corticosteroids. The median follow-up was 722 days. LI2 was associated with a 28-day mortality HR of 33.1 (95% CI: 3.8-287.3), similar to LI7 (HR: 13.2; 95% CI: 2.2-81.2). AUCs for 28-day mortality were 0.818 for LI2, 0.794 for LI4, and 0.809 for LI7 (p>0.05). The proportion of patients classified by prognosis was similar for LI2 vs. LI7 (p=0.752) and LI4 vs. LI7 (p=0.771). Concordance between LI2 and LI7 was 85%, and between LI4 and LI7, 93.33%.</p><p><strong>Conclusions: </strong>LI2 and LI4 were comparable to LI7 in predicting short-term mortality in SAH. Earlier calculation, particularly LI2, could anticipate clinical decisions in poor prognosis patients, such as corticosteroid discontinuation or evaluation for liver transplantation in selected cases.</p>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502517"},"PeriodicalIF":2.2,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144368789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Guberna Blanco, Tamara Llamero Sanz, Concepción de La Plaza Román, Javier Pérez-Bedmar Delgado
{"title":"Diagnosis of a fibroid inflammatory polyp in a patient with previous Enterobius vermicularis infection.","authors":"Laura Guberna Blanco, Tamara Llamero Sanz, Concepción de La Plaza Román, Javier Pérez-Bedmar Delgado","doi":"10.1016/j.gastrohep.2025.502516","DOIUrl":"10.1016/j.gastrohep.2025.502516","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502516"},"PeriodicalIF":2.2,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guillermo Castillo-López, Carmen García Huerta, César Prieto de Frías, José María Riesco López
{"title":"Oesophageal mucosal bridge: An unexpected endoscopic finding.","authors":"Guillermo Castillo-López, Carmen García Huerta, César Prieto de Frías, José María Riesco López","doi":"10.1016/j.gastrohep.2025.502499","DOIUrl":"10.1016/j.gastrohep.2025.502499","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502499"},"PeriodicalIF":2.2,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raúl Fernández García, Marta Lecuona Muñoz, Eduardo Redondo Cerezo, Maria Del Carmen Fernández Cano
{"title":"Double pylorus: An uncommon complication of peptic ulcer.","authors":"Raúl Fernández García, Marta Lecuona Muñoz, Eduardo Redondo Cerezo, Maria Del Carmen Fernández Cano","doi":"10.1016/j.gastrohep.2025.502498","DOIUrl":"10.1016/j.gastrohep.2025.502498","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502498"},"PeriodicalIF":2.2,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144208331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manuel González Bermúdez, María Lourdes García Jiménez, Sergio Rodríguez Rojo, Jose Antonio Romero González, Pablo Concheiro Coello, Javier Aguirrezabalaga González, José Francisco Noguera Aguilar
{"title":"Analysis of risk factors for complications after protective ileostomy reconstruction in patients operated on for rectal cancer.","authors":"Manuel González Bermúdez, María Lourdes García Jiménez, Sergio Rodríguez Rojo, Jose Antonio Romero González, Pablo Concheiro Coello, Javier Aguirrezabalaga González, José Francisco Noguera Aguilar","doi":"10.1016/j.gastrohep.2025.502495","DOIUrl":"10.1016/j.gastrohep.2025.502495","url":null,"abstract":"<p><strong>Objective: </strong>To estimate the incidence of complications following ileostomy reversal and to identify associated risk factors.</p><p><strong>Patients and methods: </strong>A retrospective cohort study was conducted, including patients who underwent rectal cancer surgery with a protective ileostomy. The minimum follow-up period was one year. A univariate analysis was performed to identify potential risk factors for complications, and variables with P<0.1 were included in a multivariate analysis.</p><p><strong>Results: </strong>Between January 1, 2015, and December 31, 2023, a total of 220 patients underwent surgery. Thirteen percent did not undergo ileostomy reversal. Thus, 193 patients were included in the final analysis. The median time to ileostomy reversal was 292 days. Postoperative complications occurred in approximately 27.5% of cases. Among the potential risk factors, albumin levels <4g/dl, open surgical approach for rectal pathology, absence of efferent loop stimulation, and side-to-side anastomosis were associated with P<.1 in univariate analysis. In the multivariate analysis, only low albumin levels and the open surgical approach for rectal pathology remained significantly associated with an increased risk of complications.</p><p><strong>Conclusion: </strong>Modifiable factors such as the use of a laparoscopic approach for rectal surgery, stimulation of the efferent loop, and optimization of preoperative nutritional status may help reduce the incidence of postoperative complications.</p>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502495"},"PeriodicalIF":2.2,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144208330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara Sánchez Moreno, Ana Plaza Fernández, Francisca Anguita Montes
{"title":"Windsock duodenal diverticulum: An unusual cause of upper gastrointestinal bleeding.","authors":"Sara Sánchez Moreno, Ana Plaza Fernández, Francisca Anguita Montes","doi":"10.1016/j.gastrohep.2025.502497","DOIUrl":"10.1016/j.gastrohep.2025.502497","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502497"},"PeriodicalIF":2.2,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144208332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ignacio Antonio Gemio Del Rey, Roberto de la Plaza Llamas, Daniel Alejandro Díaz Candelas, Ludovica Gorini, Rodrigo Arellano González
{"title":"Use of PET in preoperative malignancy determination of gastric schwannomas. Systematic review and contribution of a case.","authors":"Ignacio Antonio Gemio Del Rey, Roberto de la Plaza Llamas, Daniel Alejandro Díaz Candelas, Ludovica Gorini, Rodrigo Arellano González","doi":"10.1016/j.gastrohep.2025.502496","DOIUrl":"10.1016/j.gastrohep.2025.502496","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502496"},"PeriodicalIF":2.2,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aingeru Sarriugarte Lasarte, Hector Marín Ortega, Miren San Martin Murillo, Silvia Perez Fernandez, Gerardo Moro Portela, Beatriz Villota Tamayo, Javier Uriarte Gonzalez, Jasone Larrea Oleaga, Raul Saa Álvarez
{"title":"Evaluation of the «textbook outcomes» surgery quality indicator as a good prognostic factor for pancreatic adenocarcinoma.","authors":"Aingeru Sarriugarte Lasarte, Hector Marín Ortega, Miren San Martin Murillo, Silvia Perez Fernandez, Gerardo Moro Portela, Beatriz Villota Tamayo, Javier Uriarte Gonzalez, Jasone Larrea Oleaga, Raul Saa Álvarez","doi":"10.1016/j.gastrohep.2025.502493","DOIUrl":"10.1016/j.gastrohep.2025.502493","url":null,"abstract":"<p><strong>Objectives: </strong>Pancreatic surgery is burdened with high morbidity and mortality. There are quality indicators of the surgical process known as textbook outcomes (TO) that have been validated in areas such as esophagogastric surgery or liver surgery, and are beginning to be used in pancreatic surgery. This indicator assesses the absence of: 1) Mortality, 2) Pancreatic fistula, 3) Hemorrhage, 4) Biliary fistula, 5) Clavien-Dindo>II and 6) Readmission; TO is considered if all criteria are got. The aim of this study is to assess the impact of the achievement of TO on the prognosis of pancreatic adenocarcinoma.</p><p><strong>Patients and methods: </strong>Retrospective comparative study between two periods; before and after the creation of a pancreatic surgery unit. The results have been evaluated using Textbook Outcomes and the impact on survival of the achievement of these criteria was analyzed.</p><p><strong>Results: </strong>A total of 185 patients with pancreatic adenocarcinoma were analyzed, divided into two 5-year periods before and after the creation of the pancreatic surgery unit. There were no significant differences in clinical-pathological variables. Since the creation of the unit, TO achievement increased from 47 to 80.7% (P<.05). The OS of patients at 1, 2, and 3 years in the groups with and without TO criteria fulfillment was 86.9, 55.7, 41 and 62.7, 40.3 and 31.3% respectively, with a statistically significant difference as shown in Image 1 (P=.013). Multivariate analysis of OS showed that compliance with all TOs significantly affects mortality (HR: 0.5 [0.31-0.81]; P=.004).</p><p><strong>Conclusion: </strong>The results support the hypothesis that the achievement of the TO surgical quality criteria has a positive impact on the oncological prognosis of curative surgery for pancreatic cancer. Centralization of pancreatic cancer surgery could help to meet the surgical quality criteria largely and thus improve the prognosis of patients.</p>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502493"},"PeriodicalIF":2.2,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paula Sirera-Sirera, Núria Lluís, Fèlix Lluís, Pedro Zapater, Pablo López-Guillén, José M Ramia-Ángel, Rahma Amrani, Trinidad Castillo-García, José Andreu-Viseras, Karina Cárdenas-Jaén, Lucía Guilabert, Sara Pérez-Brotons, Emma Martínez-Moneo, Nerea Gendive-Martin, Iván González Hermoso, Enrique de-Madaria, María José Ferri
{"title":"Fecal elastase-1 and <sup>13</sup>C-mixed triglyceride breath test vs. coefficient of fat absorption to diagnose exocrine pancreatic insufficiency after pancreatic surgery.","authors":"Paula Sirera-Sirera, Núria Lluís, Fèlix Lluís, Pedro Zapater, Pablo López-Guillén, José M Ramia-Ángel, Rahma Amrani, Trinidad Castillo-García, José Andreu-Viseras, Karina Cárdenas-Jaén, Lucía Guilabert, Sara Pérez-Brotons, Emma Martínez-Moneo, Nerea Gendive-Martin, Iván González Hermoso, Enrique de-Madaria, María José Ferri","doi":"10.1016/j.gastrohep.2025.502492","DOIUrl":"10.1016/j.gastrohep.2025.502492","url":null,"abstract":"<p><strong>Objective: </strong>Exocrine pancreatic insufficiency (EPI) is common after pancreatic surgery. In patients with chronic pancreatitis, our previous results supported the use of fecal elastase-1 (FE-1) over the <sup>13</sup>C-mixed triglyceride breath test (<sup>13</sup>C-MTBT) for the diagnosis of EPI. However, it is poorly established how the performance of these two tests compares to the diagnosis of EPI after pancreatic surgery.</p><p><strong>Patients and methods: </strong>FE-1 and <sup>13</sup>C-MTBT were compared with the gold standard coefficient of fat absorption (CFA). Area under ROC curve (AUC) and best cutoffs were used to assess presence of EPI. Patient characteristics were evaluated by extent of pancreatic resection.</p><p><strong>Results: </strong>The AUC (95% confidence interval) was 0.724 (0.578-0.871) for FE-1 and 0.640 (0.482-0.799) for <sup>13</sup>C-MTBT in the diagnosis of EPI. A pairwise comparison of the FE-1 and <sup>13</sup>C-MTBT AUCs showed no statistically significant difference (P=.20). The best cut-off point was 65.5μg/g for FE-1 and 22.5% for <sup>13</sup>C-MTBT. According to contingency analysis, both the FE-1 threshold of 65.5μg/g (P=.005) and the <sup>13</sup>C-MTBT threshold of 22.5% (P=.015) showed statistical significance for diagnosing EPI.</p><p><strong>Conclusion: </strong>FE-1 was more accurate for diagnosing EPI after pancreatic surgery, but the differences were not statistically different.</p>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502492"},"PeriodicalIF":2.2,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}