Gastroenterologia y hepatologia最新文献

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Corrigendum to «Guía de práctica clínica multidisciplinar de manejo de la esteatosis hepática metabólica» Gastroenterología y Hepatología 48 (2025) 502442 《代谢性肝阻滞症管理多学科临床实践指南》更正,胃肠病学和肝病48 (2025)502442
IF 1.9 4区 医学
Gastroenterologia y hepatologia Pub Date : 2026-05-01 Epub Date: 2026-01-31 DOI: 10.1016/j.gastrohep.2025.502640
Manuel Romero-Gómez , Javier Escalada , Mar Noguerol , Antonio Pérez , Juana Carretero , Javier Crespo , Juan J. Mascort , Ignacio Aguilar , Francisco Tinahones , Pedro Cañones , Ricardo Gómez-Huelgas , Daniel de Luis , Idoia Genúa Trullos , Rocío Aller , Miguel A. Rubio , José Luis Calleja
{"title":"Corrigendum to «Guía de práctica clínica multidisciplinar de manejo de la esteatosis hepática metabólica» Gastroenterología y Hepatología 48 (2025) 502442","authors":"Manuel Romero-Gómez , Javier Escalada , Mar Noguerol , Antonio Pérez , Juana Carretero , Javier Crespo , Juan J. Mascort , Ignacio Aguilar , Francisco Tinahones , Pedro Cañones , Ricardo Gómez-Huelgas , Daniel de Luis , Idoia Genúa Trullos , Rocío Aller , Miguel A. Rubio , José Luis Calleja","doi":"10.1016/j.gastrohep.2025.502640","DOIUrl":"10.1016/j.gastrohep.2025.502640","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 5","pages":"Article 502640"},"PeriodicalIF":1.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147854238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hepatitis enfisematosa: diagnóstico radiológico y correlación intraoperatoria de una patología infecciosa extraordinariamente infrecuente “肺泡性肝炎:一种极其罕见的传染病的放射诊断和术后相关性”。
IF 1.9 4区 医学
Gastroenterologia y hepatologia Pub Date : 2026-05-01 Epub Date: 2025-12-04 DOI: 10.1016/j.gastrohep.2025.502637
Paloma Montosa Ródenas, Sergio Molina Espinoza, Manuel Jesús Rabaza Espigares, Antonio Jesús Láinez Ramos-Bossini
{"title":"Hepatitis enfisematosa: diagnóstico radiológico y correlación intraoperatoria de una patología infecciosa extraordinariamente infrecuente","authors":"Paloma Montosa Ródenas, Sergio Molina Espinoza, Manuel Jesús Rabaza Espigares, Antonio Jesús Láinez Ramos-Bossini","doi":"10.1016/j.gastrohep.2025.502637","DOIUrl":"10.1016/j.gastrohep.2025.502637","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 5","pages":"Article 502637"},"PeriodicalIF":1.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145696086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Más allá del TIPS permeable: El papel del PET/TC en la endoTIPSitis 超越渗透性TIPS: PET-CT在内窥镜炎中的诊断作用。
IF 1.9 4区 医学
Gastroenterologia y hepatologia Pub Date : 2026-05-01 Epub Date: 2025-12-18 DOI: 10.1016/j.gastrohep.2025.502643
Julio Otero Figar, Daniel Muíño Dominguez, Inés Magide Yañez, Mario Álvarez Diez, Blanca Mesonero de la Cruz, Elena Granda Villanueva, Javier Fernández Gil, María Ponte Romo, Ana Diaz Simal, Lissa Franco Aguirre
{"title":"Más allá del TIPS permeable: El papel del PET/TC en la endoTIPSitis","authors":"Julio Otero Figar, Daniel Muíño Dominguez, Inés Magide Yañez, Mario Álvarez Diez, Blanca Mesonero de la Cruz, Elena Granda Villanueva, Javier Fernández Gil, María Ponte Romo, Ana Diaz Simal, Lissa Franco Aguirre","doi":"10.1016/j.gastrohep.2025.502643","DOIUrl":"10.1016/j.gastrohep.2025.502643","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 5","pages":"Article 502643"},"PeriodicalIF":1.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Etrasimod: revisión de la seguridad y las consideraciones prácticas de manejo de una nueva terapia oral para el tratamiento de la colitis ulcerosa 伊特拉西莫德:一种治疗溃疡性结肠炎的新型口服疗法的安全性和实际管理考虑的综述。
IF 1.9 4区 医学
Gastroenterologia y hepatologia Pub Date : 2026-05-01 Epub Date: 2025-12-20 DOI: 10.1016/j.gastrohep.2025.502647
Yamile Zabana , Ana Cábez , Ana Gutiérrez Casbas
{"title":"Etrasimod: revisión de la seguridad y las consideraciones prácticas de manejo de una nueva terapia oral para el tratamiento de la colitis ulcerosa","authors":"Yamile Zabana ,&nbsp;Ana Cábez ,&nbsp;Ana Gutiérrez Casbas","doi":"10.1016/j.gastrohep.2025.502647","DOIUrl":"10.1016/j.gastrohep.2025.502647","url":null,"abstract":"<div><div>Modulation of sphingosine-1-phosphate receptors represents a relatively recent approach in the treatment of inflammatory bowel disease, although these modulators have been approved since 2010 for other inflammatory conditions such as multiple sclerosis. Etrasimod is a sphingosine-1-phosphate receptor (S1PR) modulator that binds to S1PR1, S1PR4 and S1PR5 receptors, and its efficacy has been demonstrated in the treatment of moderately to severely active ulcerative colitis. It is a small molecule and synthetic drug administered orally, with a proper bioavailability and a fast elimination rate, predictable pharmacokinetics and lack of immunogenicity, which are convenient characteristics for both efficacy and safety. This article reviews the pharmacological characteristics of etrasimod and its safety profile.</div></div>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 5","pages":"Article 502647"},"PeriodicalIF":1.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145809780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Argentinian Crohn's Disease and Ulcerative Colitis Registry (RADECCU): Methodological aspects and objectives 阿根廷克罗恩病和溃疡性结肠炎登记处(RADECCU):方法方面和目标。
IF 1.9 4区 医学
Gastroenterologia y hepatologia Pub Date : 2026-05-01 Epub Date: 2026-01-09 DOI: 10.1016/j.gastrohep.2026.502652
Domingo Balderramo , Joaquín Montero , Juan Lasa , Ramiro Cruz González Sueyro , Pablo Andrés Olivera , Alicia Sambuelli , Abel Novillo , Juan Andrés De Paula
{"title":"The Argentinian Crohn's Disease and Ulcerative Colitis Registry (RADECCU): Methodological aspects and objectives","authors":"Domingo Balderramo ,&nbsp;Joaquín Montero ,&nbsp;Juan Lasa ,&nbsp;Ramiro Cruz González Sueyro ,&nbsp;Pablo Andrés Olivera ,&nbsp;Alicia Sambuelli ,&nbsp;Abel Novillo ,&nbsp;Juan Andrés De Paula","doi":"10.1016/j.gastrohep.2026.502652","DOIUrl":"10.1016/j.gastrohep.2026.502652","url":null,"abstract":"<div><h3>Objective</h3><div>There is little information available at the national level on inflammatory bowel disease (IBD) in Argentina. The objective was to describe the methodology of the Argentinian Crohn's Disease and Ulcerative Colitis Registry (RADECCU).</div></div><div><h3>Patient and methods</h3><div>RADECCU was developed in 2023 with the aim of facilitating the collection of relevant information from patients with IBD in Argentina. After the registry's website platform was developed (01/2023), a nationwide promotion campaign was carried out to incorporate centers into RADECCU.</div></div><div><h3>Results</h3><div>From 02/2023 to 6/2025, 69 centers (41 private, 28 public) were incorporated, including 142 professionals, and 4081 patients (2275 women and 1806 men) were enrolled in the registry.</div></div><div><h3>Conclusion</h3><div>RADECCU is the first national IBD registry in Argentina. This registry will provide information on the status of IBD in Argentina and contribute to Latin American data with the potential to generate real-world evidence on different aspects of interest.</div></div>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 5","pages":"Article 502652"},"PeriodicalIF":1.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145951156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fístulas perianales complejas: no todo es enfermedad de Crohn 复杂的肛周瘘:并不是所有的克罗恩病。
IF 1.9 4区 医学
Gastroenterologia y hepatologia Pub Date : 2026-05-01 Epub Date: 2026-01-22 DOI: 10.1016/j.gastrohep.2026.502663
Anna Porta-Vilaro , Patricia Garbayo-Salmons , Lucía Madero , Margalida Calafat , Iria Baston-Rey , Eduard Brunet-Mas , Grupo Joven de Geteccu
{"title":"Fístulas perianales complejas: no todo es enfermedad de Crohn","authors":"Anna Porta-Vilaro ,&nbsp;Patricia Garbayo-Salmons ,&nbsp;Lucía Madero ,&nbsp;Margalida Calafat ,&nbsp;Iria Baston-Rey ,&nbsp;Eduard Brunet-Mas ,&nbsp;Grupo Joven de Geteccu","doi":"10.1016/j.gastrohep.2026.502663","DOIUrl":"10.1016/j.gastrohep.2026.502663","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 5","pages":"Article 502663"},"PeriodicalIF":1.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146043981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infección por Clostridioides difficile: Documento de posicionamiento de la Societat Catalana de Digestologia 艰难梭菌感染:加泰罗尼亚胃肠病学会的立场文件。
IF 1.9 4区 医学
Gastroenterologia y hepatologia Pub Date : 2026-05-01 Epub Date: 2026-01-15 DOI: 10.1016/j.gastrohep.2025.502634
Clàudia Aràjol , Begoña González Suárez , María Bonilla Moreno , Mireia Puig-Asensio , Virginia Robles-Alonso , Gerard Surís , Cristina Solé , José Ramón Santos , Lorena Rodríguez-Alonso
{"title":"Infección por Clostridioides difficile: Documento de posicionamiento de la Societat Catalana de Digestologia","authors":"Clàudia Aràjol ,&nbsp;Begoña González Suárez ,&nbsp;María Bonilla Moreno ,&nbsp;Mireia Puig-Asensio ,&nbsp;Virginia Robles-Alonso ,&nbsp;Gerard Surís ,&nbsp;Cristina Solé ,&nbsp;José Ramón Santos ,&nbsp;Lorena Rodríguez-Alonso","doi":"10.1016/j.gastrohep.2025.502634","DOIUrl":"10.1016/j.gastrohep.2025.502634","url":null,"abstract":"<div><h3>Introduction</h3><div><em>Clostridioides difficile</em> infection (CDI) is the leading cause of healthcare-associated infectious diarrhea and is associated with significant morbidity and mortality, primarily due to its high recurrence rate. For this reason, the Catalan Society of Gastroenterology commissioned the development of a position paper aimed at providing practical recommendations, grounded in scientific evidence and expert consensus, on the diagnosis and management of CDI.</div></div><div><h3>Methods</h3><div>This position paper was developed by specialists in Gastroenterology, Infectious Diseases and Microbiology. It was based on a non-systematic review of the scientific evidence. Recommendations were formulated through expert consensus.</div></div><div><h3>Results</h3><div>The document presents a structured approach to the diagnosis and treatment of CDI, emphasizing individualized management and strategies to reduce recurrence rates. Key components include the role of fecal microbiota transplantation and a therapeutic algorithm informed by disease severity and by whether the episode is initial or recurrent.</div></div><div><h3>Conclusions</h3><div>This position paper aims to serve as a practical, evidence-based guide for healthcare professionals involved in the clinical management of CDI, promoting the implementation of optimal therapeutic strategies and addressing the main challenges associated with this infection.</div></div>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 5","pages":"Article 502634"},"PeriodicalIF":1.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145994423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recommendations for the diagnosis of patients with hepatitis delta virus (HDV) in Spain. 西班牙丁型肝炎病毒(HDV)患者诊断建议
IF 1.9 4区 医学
Gastroenterologia y hepatologia Pub Date : 2026-04-28 DOI: 10.1016/j.gastrohep.2026.502768
María Buti, Antonio Aguilera, José Luis Calleja, José María Molero, Pablo Ryan, José Joaquín Antón Basanta, Raquel Domínguez-Hernández, Alberto De la Cuadra-Grande, Federico García
{"title":"Recommendations for the diagnosis of patients with hepatitis delta virus (HDV) in Spain.","authors":"María Buti, Antonio Aguilera, José Luis Calleja, José María Molero, Pablo Ryan, José Joaquín Antón Basanta, Raquel Domínguez-Hernández, Alberto De la Cuadra-Grande, Federico García","doi":"10.1016/j.gastrohep.2026.502768","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502768","url":null,"abstract":"<p><p>The hepatitis Delta virus (HDV), whose infection depends on the presence of the hepatitis B virus (HBV), is associated with one of the chronic viral hepatitis that most rapidly progresses to advanced liver disease, including liver cirrhosis and/or hepatocellular carcinoma. In this context, screening for HBV/HDV infection is key to the early diagnosis of hepatitis D, improving the prognosis of infected individuals through a strategy that has proven to be effective and efficient. This document reviews the epidemiology and current situation of hepatitis D in Spain, including the main barriers to its detection and diagnosis. The aim is to define recommendations for the diagnosis of hepatitis D, determined by a multidisciplinary experts panel. Regarding screening, recommendations are established in relation to: 1) settings and populations where screening is indicated; 2) optimization of HDV detection (reflex testing and point-of-care testing); and 3) the frequency for the test to be repeated. Regarding diagnosis, the following aspects are addressed: 1) how to diagnose HDV infection (double reflex test); 2) what characteristics are present in the tests currently available to determine HDV-RNA; and 3) possible solutions to overcome the current barriers in the diagnosis of the infection. These recommendations contribute to improving the prognosis for hepatitis D and, additionally, represent a step toward eliminating viral hepatitis by 2030, a goal set by the World Health Organization.</p>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502768"},"PeriodicalIF":1.9,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147814190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hepatic PEComa: a diagnostic and therapeutic challenge. 肝PEComa:诊断和治疗的挑战。
IF 1.9 4区 医学
Gastroenterologia y hepatologia Pub Date : 2026-04-28 DOI: 10.1016/j.gastrohep.2026.502769
Isabel Company Ricart, María José Naharro Gascón, Manuel Bellver Oliver, Carlos Domingo Del Pozo
{"title":"Hepatic PEComa: a diagnostic and therapeutic challenge.","authors":"Isabel Company Ricart, María José Naharro Gascón, Manuel Bellver Oliver, Carlos Domingo Del Pozo","doi":"10.1016/j.gastrohep.2026.502769","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502769","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502769"},"PeriodicalIF":1.9,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147814119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Human intestinal spirochetosis: clinicopathological features in patients from a Chilean Academic Health Network. 人类肠道螺旋体病:智利学术健康网络患者的临床病理特征。
IF 1.9 4区 医学
Gastroenterologia y hepatologia Pub Date : 2026-04-22 DOI: 10.1016/j.gastrohep.2026.502767
O Corsi, B Riffo, F Pinochet, M Ballart, J Chahuán, T Reyes, T Feuerhake, J Torres
{"title":"Human intestinal spirochetosis: clinicopathological features in patients from a Chilean Academic Health Network.","authors":"O Corsi, B Riffo, F Pinochet, M Ballart, J Chahuán, T Reyes, T Feuerhake, J Torres","doi":"10.1016/j.gastrohep.2026.502767","DOIUrl":"https://doi.org/10.1016/j.gastrohep.2026.502767","url":null,"abstract":"<p><strong>Objective: </strong>To describe clinical features, endoscopic and histological findings, and follow up in patients with Human intestinal spirochetosis (HIS) from a Chilean academic health center.</p><p><strong>Patients and methods: </strong>A retrospective review was conducted on HIS cases diagnosed in an academic health network in Santiago de Chile between 2018 and 2022. Clinical, endoscopic, histopathological, therapeutic, and follow-up information was collected.</p><p><strong>Results: </strong>Sixteen colonic samples were identified (0.03% of all colonoscopies). The median age was 40 years, 75% were male, and 33% had an antecedent of HIV infection. All patients reported symptoms: diarrhea (67%), abdominal pain (40%), and gastrointestinal bleeding (27%). The majority (69%) had a normal-appearing mucosa upon endoscopy, and the finding of spirochetes occurred predominantly in step biopsies (75%). Histopathological analysis revealed normal mucosal architecture in 88% of cases. Post-colonoscopy follow-up was achieved for 10 patients, 4 of whom received antibiotics with subsequent symptom resolution in the three with post-treatment follow-up. All followed-up patients who did not receive antibiotics reported symptom resolution.</p><p><strong>Conclusion: </strong>HIS is infrequent and predominantly colonic. Most cases are men, have a history of a sexually transmitted infection, present with gastrointestinal symptoms, and often have a normal colonoscopy. Most samples do not exhibit significant histopathological changes beyond superficial bacterial colonization.</p>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502767"},"PeriodicalIF":1.9,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147769764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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