Gastroenterologia y hepatologia最新文献

{"title":"Transmural air leakage after endoscopic submucosal dissection in the distal rectum","authors":"Eduardo Rodríguez-Hernández, Antonio Zebenzuy Gimeno-García, Ibrahim Hernández-González, David Nicolás-Pérez","doi":"10.1016/j.gastrohep.2026.502707","DOIUrl":"10.1016/j.gastrohep.2026.502707","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 8","pages":"Article 502707"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147304904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Food-related quality of life in inflammatory bowel disease: Validity and reliability of the Brazilian version of the FR-QoL-29-Portuguese-Brazil","authors":"Isadora Sayuri Macedo Tuma,&nbsp;Maria Paula Carlin Cambi,&nbsp;Sara Fernanda de Oliveira Dominski,&nbsp;Patrícia Ignácio,&nbsp;Daniéla Oliveira Magro,&nbsp;Kevin Whelan,&nbsp;Paulo Gustavo Kotze","doi":"10.1016/j.gastrohep.2026.502754","DOIUrl":"10.1016/j.gastrohep.2026.502754","url":null,"abstract":"<div><h3>Objective</h3><div>Our aim was to (i) undertake a comprehensive translation of the FR-QoL-29 instrument to Brazilian-Portuguese; and (ii) evaluate its validity and reliability in patients with IBD in Brazil.</div></div><div><h3>Materials and methods</h3><div>The FR-QoL-29 underwent forward and backward translation to Brazilian-Portuguese. A cross-sectional study was conducted in patients with IBD either in remission or with active disease at a tertiary referral center in Brazil. Clinical and demographic characteristics, Montreal classification and anthropometric measurements were collected. Data were compared with controls without any gastrointestinal disease.</div></div><div><h3>Results</h3><div>A total of 203 consecutive patients were included, of whom 173 had IBD and 30 were controls. Cronbach's <em>α</em> was 0.93 for IBD patients without previous IBD-related surgery, 0.93 for IBD patients with previous intestinal surgery, and 0.80 for the control group. Using the Kaiser–Meyer–Olkin (KMO) test to assess sample adequacy, the result was 0.85 for IBD patients without previous surgery (<em>p</em> <!-->&lt;<!--> <!-->0.001) and 0.73 for those with previous IBD-related operations (<em>p</em> <!-->&lt;<!--> <!-->0.001).</div></div><div><h3>Conclusion</h3><div>The FR-QoL-29-Portuguese-Brazil is a valid and reliable tool for use in this language and in this specific population to measure the important factor of food-related quality of life.</div></div>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 8","pages":"Article 502754"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147616024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comentario: «Recomendaciones de vacunación y adherencia en la enfermedad inflamatoria intestinal: un estudio de discordancia médico-paciente»: Todavía es necesario mejorar","authors":"Rodrigo Quera,&nbsp;Paulina Núñez,&nbsp;Lilian Flores","doi":"10.1016/j.gastrohep.2026.502781","DOIUrl":"10.1016/j.gastrohep.2026.502781","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 8","pages":"Article 502781"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148005071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laceración esplénica como complicación tras una colonoscopia diagnóstica","authors":"María Calderón Chamizo,&nbsp;José Manuel Tapia Cabo,&nbsp;Julia Ternero Fonseca,&nbsp;Alberto Naranjo Pérez,&nbsp;Alberto Pérez Ramírez","doi":"10.1016/j.gastrohep.2026.502657","DOIUrl":"10.1016/j.gastrohep.2026.502657","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 8","pages":"Article 502657"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146044018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Population-based real-world adoption of advanced therapies for ulcerative colitis in Brazil: Trends and regional differences from a nationwide public healthcare database","authors":"Maria Paz Gimenez Villamil,&nbsp;Maria Victoria Bein,&nbsp;Douglas Andreas Valverde,&nbsp;Mariane Christina Savio,&nbsp;Rafaela Araújo Molteni Moretti,&nbsp;Thyago Proença de Moraes,&nbsp;Abel Botelho Quaresma,&nbsp;Paulo Gustavo Kotze","doi":"10.1016/j.gastrohep.2026.502762","DOIUrl":"10.1016/j.gastrohep.2026.502762","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate temporal trends and regional differences in the use of advanced therapies for ulcerative colitis (UC) within Brazil's public healthcare system.</div></div><div><h3>Patients and methods</h3><div>Retrospective population-based study using Brazilian Department of Informatics of the Unified Health System (DATASUS) data (2019–2023). Patients with an ICD-10 code for UC were included. Monthly dispensing rates of infliximab, vedolizumab, and tofacitinib were analyzed.</div></div><div><h3>Results</h3><div>By 2023, 195,807 UC patients were identified. Administrative prevalence increased from 26.37 to 62.47 per 100,000 inhabitants. Nationwide use of advanced therapies rose significantly. Vedolizumab showed the highest Annual Average Percent Change (AAPC) (+8.5%), followed by tofacitinib (+4.8%) and infliximab (+1.02%). The Southeast demonstrated the greatest growth, whereas the Northeast showed a significant decline across all therapies.</div></div><div><h3>Conclusion</h3><div>UC prevalence increased markedly in Brazil, with persistent regional disparities in advanced therapy use.</div></div>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 8","pages":"Article 502762"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147662357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computer-assisted adenoma detection colonoscopy with an ENDO-AID artificial intelligence system and Endocuff- versus Endocuff-assisted colonoscopy: A randomized controlled trial","authors":"Antonio Z. Gimeno-García,&nbsp;Anjara Hernández,&nbsp;Domingo Hernández Negrin,&nbsp;Eduardo Rodríguez,&nbsp;Gloria Lorenzo,&nbsp;Jorge Mon,&nbsp;Rafael Romero,&nbsp;Alejandro Jiménez,&nbsp;Vanessa Felipe,&nbsp;Zaida Adrián,&nbsp;Raquel de la Barreda,&nbsp;Juan Ortega,&nbsp;Yaiza Cedrés,&nbsp;Manuel Hernández-Guerra,&nbsp;David Nicolás-Pérez","doi":"10.1016/j.gastrohep.2026.502757","DOIUrl":"10.1016/j.gastrohep.2026.502757","url":null,"abstract":"<div><h3>Background</h3><div>Compared with conventional colonoscopy, computer-assisted adenoma detection (CADe) colonoscopy and Endocuff-Vision (EV) have been shown to increase the adenoma detection rate (ADR). However, the evidence for whether their combination further increases the ADR compared with that of EV alone is limited. The aim was to compare the combination of CADe and EV, with EV alone.</div></div><div><h3>Methods</h3><div>In all, 696 patients were randomized 1:1 to receive either CADe (ENDO-AID [OIP-1]) plus EV or EV alone at a tertiary care hospital. The primary outcome was the ADR. The secondary outcomes included the advanced ADR and the number of adenomas per colonoscopy (APC). Both intention-to-treat (ITT) and per-protocol (PP) analyses were conducted for the primary outcome.</div></div><div><h3>Results</h3><div>In the ITT analysis, the ADR was 54.6% and 51.1% in the combination and EV groups, respectively (OR 1.15, 95% CI (0.85–1.55)). In the PP analysis, the ADRs were 58.7% and 56.6%, respectively (OR 1.09, 95% CI (0.79–1.52)), for the combination and EV groups. The ADR in the proximal colon was significantly greater in the combination group than in the EV group (39.6% vs. 30%; <em>P</em> <!-->=<!--> <!-->0.015). The APC value was significantly greater in the combination group than in the EV group (mean: 1.7, SD: 2.34 vs. mean: 1.31, SD: 1.92; <em>P</em> <!-->=<!--> <!-->0.029), which was primarily due to increased detection of flat diminutive adenomas.</div></div><div><h3>Conclusions</h3><div>Compared with EV alone, colonoscopy assisted by both ENDO-AID (OIP-1) and EV does not significantly increase the ADR. However, this combination may be beneficial for the detection of proximal and diminutive flat adenomas (<span><span>NCT05141773</span><svg><path></path></svg></span>).</div></div>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 8","pages":"Article 502757"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147618319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vaccination recommendations and adherence in inflammatory bowel disease: A physician–patient discordance study","authors":"Rocío Ferreiro-Iglesias,&nbsp;Alejandro Hernández-Camba,&nbsp;Antonio Valdivia,&nbsp;Iago Rodríguez-Lago,&nbsp;Yamile Zabana,&nbsp;Manuel Barreiro-de Acosta,&nbsp;on behalf of the GETECCU Youth Group and ACCU Spain","doi":"10.1016/j.gastrohep.2026.502714","DOIUrl":"10.1016/j.gastrohep.2026.502714","url":null,"abstract":"<div><h3>Objective</h3><div>Despite specific recommendations, immunization rates among patients with inflammatory bowel disease (IBD) remain suboptimal. This study aimed to assess vaccination management by exploring the concordance and discordance between physicians’ reported vaccination recommendations and patients’ recall of having received those recommendations, as well as patients’ adherence following a medical recommendation.</div></div><div><h3>Patients and methods</h3><div>An anonymous online survey was sent to 8000 patients from a national patient association (ACCU Spain) and 1000 members of the Spanish IBD Working Group (GETECCU).</div></div><div><h3>Results</h3><div>A total of 144 physicians and 1302 patients responded (mean age of 43 years). Almost all physicians expressed concern about vaccination in IBD and 63% deemed them very important. Although 69% of physicians reported recommending influenza vaccination during pregnancy, only 11.1% of pregnant patients recalled having received such advice. Among patients who reported having received a vaccination recommendation, adherence varied widely by vaccine type, ranging from 55% for HPV to over 80% for influenza, pneumococcal, hepatitis B, and tetanus vaccines. The main reasons for non-adherence were the perception that vaccination was unnecessary and fear of adverse events.</div></div><div><h3>Conclusions</h3><div>Discordance exists between physicians’ reported vaccination practices and patients’ recall of the information received. Although physicians awareness is high, communication gaps and other barriers may limit effective implementation.</div></div>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 8","pages":"Article 502714"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147354721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Documento de consenso sobre el diagnóstico, manejo y tratamiento de la infección crónica por el virus de la hepatitis B y por el virus de la hepatitis D en España","authors":"Sabela Lens,&nbsp;Federico García,&nbsp;Juanjo Mascort,&nbsp;Marta Casado,&nbsp;Carolina Freyre,&nbsp;Alicia Lázaro,&nbsp;Gema Muñoz,&nbsp;Cristina Molera,&nbsp;Javier García-Samaniego,&nbsp;María Buti,&nbsp;Representantes de las sociedades científicas","doi":"10.1016/j.gastrohep.2026.502717","DOIUrl":"10.1016/j.gastrohep.2026.502717","url":null,"abstract":"<div><div>Chronic infection by hepatitis B virus (HBV) and hepatitis D virus (HDV) continues to pose a major public health challenge in Spain due to its high morbidity and mortality and the risk of progression to cirrhosis and hepatocellular carcinoma. Although effective tools exist for the control of hepatitis B and recent therapeutic advances have been made for hepatitis D, significant inequalities persist in early diagnosis, access to treatment, and appropriate patient follow-up. This consensus document has been jointly developed by the Spanish Association for the Study of the Liver (AEEH), the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC)—through its Viral Hepatitis Study Group (GEHEP)—the Spanish Society of Digestive Pathology (SEPD), the Spanish Society of Family and Community Medicine (semFYC), the Spanish Society of Hospital Pharmacy (SEFH), the Alliance for the Elimination of Viral Hepatitis in Spain (AEHVE), and the Spanish Society of Paediatric Gastroenterology, Hepatology and Nutrition (SEGHNP). The objective is to provide updated and consensus-based recommendations on the diagnosis, management, and treatment of chronic HBV and HDV infection, from a multidisciplinary perspective and adapted to real-world clinical practice. The document addresses screening and diagnostic strategies, criteria for assessing liver fibrosis, indications for antiviral treatment, specific management of hepatitis D, and the role of coordination between primary care and hospital care. Likewise, it emphasizes the need to implement strategies to advance toward the goals of viral hepatitis elimination.</div></div>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 8","pages":"Article 502717"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147456673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gangrena de Fournier en paciente con carcinoma hepatocelular en tratamiento sistémico con atezolizumab más bevacizumab","authors":"Elena Granda Villanueva,&nbsp;Blanca Mesonero de la Cruz,&nbsp;Jaime Álvarez Grau,&nbsp;Andrés Curiel Elizondo,&nbsp;Lorena Carballo Folgoso,&nbsp;Andrés Castaño García","doi":"10.1016/j.gastrohep.2026.502718","DOIUrl":"10.1016/j.gastrohep.2026.502718","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 8","pages":"Article 502718"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147456638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multicystic disease of the pancreas mimicking intraductal papillary mucinous neoplasm","authors":"Zanglong Deng,&nbsp;Tao Guo,&nbsp;Tao Yin","doi":"10.1016/j.gastrohep.2026.502708","DOIUrl":"10.1016/j.gastrohep.2026.502708","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"49 8","pages":"Article 502708"},"PeriodicalIF":2.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147304947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}