Raúl Honrubia López , Aurora Burgos García , Yutaka Mitsunaga , Pedro de María Pallares , Mariana Tavecchia , Cristina Fernández de Castro
{"title":"La endoscopia de tercer espacio: una realidad para la próxima generación de endoscopistas","authors":"Raúl Honrubia López , Aurora Burgos García , Yutaka Mitsunaga , Pedro de María Pallares , Mariana Tavecchia , Cristina Fernández de Castro","doi":"10.1016/j.gastrohep.2024.502291","DOIUrl":"10.1016/j.gastrohep.2024.502291","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"48 2","pages":"Article 502291"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142686894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Javier Alcedo González , Fermín Estremera-Arévalo , Julyssa Cobián Malaver , Javier Santos Vicente , Luis Gerardo Alcalá-González , Juan Naves , Elizabeth Barba Orozco , Claudia Barber Caselles , Blanca Serrano-Falcón , Anna Accarino Garaventa , Carmen Alonso-Cotoner , Jordi Serra Pueyo
{"title":"Preguntas comunes y respuestas razonadas sobre el síndrome del sobrecrecimiento bacteriano intestinal (SIBO)","authors":"Javier Alcedo González , Fermín Estremera-Arévalo , Julyssa Cobián Malaver , Javier Santos Vicente , Luis Gerardo Alcalá-González , Juan Naves , Elizabeth Barba Orozco , Claudia Barber Caselles , Blanca Serrano-Falcón , Anna Accarino Garaventa , Carmen Alonso-Cotoner , Jordi Serra Pueyo","doi":"10.1016/j.gastrohep.2024.502216","DOIUrl":"10.1016/j.gastrohep.2024.502216","url":null,"abstract":"<div><div>The recognition and treatment of intestinal bacterial overgrowth syndrome are matters of controversy. The symptoms that have guided the search for the disorder suffer from lack of specificity, especially in the absence of well-defined predisposing factors. The accuracy of diagnostic procedures has been questioned and the proposed therapies achieve generally low effectiveness figures, with large differences between available studies. It is also unknown whether the normalization of tests is really a guarantee of cure.</div><div>Within this framework of uncertainty, and in order to contribute to the guidance and homogenization of medical practice, a group of experts from the AEG and ASENEM have formulated the key questions on the management of this pathology and have provided answers to them, in accordance with the available scientific evidence. In addition, they have drawn up statements based on the conclusions of the review and have voted on them individually to reflect the degree of consensus for each statement.</div></div>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"48 2","pages":"Article 502216"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesca Bolis , Giorgio Cazzaniga , Fabio Pagni , Pietro Invernizzi , Marco Carbone , Alessio Gerussi
{"title":"The phenotypic landscape of primary biliary cholangitis and autoimmune hepatitis variants","authors":"Francesca Bolis , Giorgio Cazzaniga , Fabio Pagni , Pietro Invernizzi , Marco Carbone , Alessio Gerussi","doi":"10.1016/j.gastrohep.2024.502225","DOIUrl":"10.1016/j.gastrohep.2024.502225","url":null,"abstract":"<div><div>Autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC) stand as distinct diseases, yet occasionally intertwine with overlapping features, posing diagnostic and management challenges. This recognition traces back to the 1970s, with initial case reports highlighting this complexity.</div><div>Diagnostic scoring systems like IAIHG and simplified criteria for AIH were introduced but are inherently limited in diagnosing variant syndromes. The so-called Paris criteria offer a diagnostic framework with high sensitivity and specificity for variant syndromes, although disagreements among international guidelines persist.</div><div>Histological findings in AIH and PBC may exhibit overlapping features, rendering histology alone inadequate for a definitive diagnosis. Autoantibody profiles could be helpful, but similarly cannot be considered alone to reach a solid and consistent evaluation.</div><div>Treatment strategies vary based on the predominant features observed.</div><div>Individuals with overlapping characteristics favoring AIH ideally benefit from corticosteroids, while patients primarily manifesting PBC features should initially receive treatment with choleretic drugs like ursodeoxycholic acid (UDCA).</div></div>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"48 2","pages":"Article 502225"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141476474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Losa , Gisela Silva , Sara Mosca , Berta Bonet , Helena Moreira Silva , Ermelinda Santos Silva
{"title":"Pediatric gallstone disease—Management difficulties in clinical practice","authors":"Ana Losa , Gisela Silva , Sara Mosca , Berta Bonet , Helena Moreira Silva , Ermelinda Santos Silva","doi":"10.1016/j.gastrohep.2024.502228","DOIUrl":"10.1016/j.gastrohep.2024.502228","url":null,"abstract":"<div><h3>Background</h3><div>Gallstone disease (GD) is no longer an exclusive condition of adulthood, and its prevalence is increasing in pediatric age. The management and the extent of the etiological investigation of GD in children and adolescents remains controversial. This study aimed to analyze the difficulties in the work-up and management of pediatric GD patients.</div></div><div><h3>Methods</h3><div>A retrospective study performed in a single tertiary center enrolled sixty-five patients with GD followed from January 2014 to June 2021. Patients were categorized conveniently according to their age at diagnosis: Group A (<10<!--> <!-->years, <em>n</em> <!-->=<!--> <!-->35) and Group B (≥10<!--> <!-->years, <em>n</em> <!-->=<!--> <!-->30). We analyzed demographic, clinical and laboratory data, ultrasonographic findings at presentation, therapeutics and complications.</div></div><div><h3>Results</h3><div>Symptoms were more frequent in patients >10<!--> <!-->years old (<em>p</em> <!-->=<!--> <!-->0.001). Cholecystectomy was performed in 31 patients (47.7%). A multivariate regression logistic model identified the age >10<!--> <!-->years (OR<!--> <!-->=<!--> <!-->6.440, <em>p</em> <!-->=<!--> <!-->0.005) and underlying entities (OR<!--> <!-->=<!--> <!-->6.823, <em>p</em> <!-->=<!--> <!-->0.017) as independent variables to perform surgery. Spontaneous resolution of GD was more common in children <2<!--> <!-->years old. A multivariate regression logistic model showed a trend for those >10<!--> <!-->years old to develop more complications. Two out of 18 patients were diagnosed with ABCB4 gene mutations in heterozygosity.</div></div><div><h3>Conclusions</h3><div>Decision-making on cholecystectomy remains challenging in asymptomatic patients. Identifying predictive factors for the development of complications has proven difficult. However, we found a trend toward the development of complications in individuals older than 10<!--> <!-->years.</div></div>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"48 2","pages":"Article 502228"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Índice de autores","authors":"","doi":"10.1016/S0210-5705(25)00116-5","DOIUrl":"10.1016/S0210-5705(25)00116-5","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"48 ","pages":"Pages S164-S174"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comunicaciones orales. Sesión General 1","authors":"","doi":"10.1016/S0210-5705(25)00107-4","DOIUrl":"10.1016/S0210-5705(25)00107-4","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"48 ","pages":"Pages S1-S5"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comunicaciones orales. Sesión General 4","authors":"","doi":"10.1016/S0210-5705(25)00110-4","DOIUrl":"10.1016/S0210-5705(25)00110-4","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"48 ","pages":"Pages S18-S22"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonietta Gerarda Gravina , Raffaele Pellegrino , Giovanna Palladino, Giuseppe Imperio, Andrea Ventura, Marina Cipullo, Annachiara Coppola, Alessandro Federico
{"title":"Profiling the patient with inflammatory bowel disease in the relationship between physical activity and partner/social network status: A post hoc patient-tailored analysis of the “BE-FIT-IBD” study","authors":"Antonietta Gerarda Gravina , Raffaele Pellegrino , Giovanna Palladino, Giuseppe Imperio, Andrea Ventura, Marina Cipullo, Annachiara Coppola, Alessandro Federico","doi":"10.1016/j.gastrohep.2024.502203","DOIUrl":"10.1016/j.gastrohep.2024.502203","url":null,"abstract":"<div><h3>Introduction</h3><div>Normal quality of life is an ultimate target in the therapeutic approach to inflammatory bowel diseases (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC) in the context of which regular physical activity (PA) is often a chimeric parameter that is not standardized in terms of quality/quantity. The study aimed to profile a sample of IBD patients about the relationship between PA-partner status and social network support.</div></div><div><h3>Patients and methods</h3><div>A <em>post hoc</em> analysis of the “BE-FIT-IBD” study was set up by stratifying the data of PA with that of partner status and the support that the patient's social network (i.e., relatives, friends) provided in inciting the patient to practice regular PA.</div></div><div><h3>Results</h3><div><span>In the 219 patients included, there was a greater tendency for patients with stable partners to view the risk of reactivation/worsening of IBD as a barrier to conducting regular PA (</span><em>p</em> <!--><<!--> <!-->0.0001). Single patients considered PA more as a protective factor (<em>p</em> <!-->=<!--> <!-->0.045). Patients without a PA-supporting social network retained IBD-related treatment as a PA barrier (<em>p</em> <!-->=<!--> <span>0.016) and PA as a risk for IBD complications (</span><em>p</em> <!-->=<!--> <span>0.01), with less confidence that PA could improve the course of IBD (</span><em>p</em> <!--><<!--> <!-->0.001). Rectal syndrome was an IBD-related barrier more represented in patients with PA-deterring social network (<em>p</em> <!--><<!--> <!-->0.0001).</div></div><div><h3>Conclusions</h3><div>These factors are potential targets for recovering the IBD patient's adherence to regular PA.</div></div>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":"48 2","pages":"Article 502203"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140897841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}