Gastroenterologia y hepatologia最新文献

{"title":"Pósteres virtuales","authors":"","doi":"10.1016/S0210-5705(24)00183-3","DOIUrl":"https://doi.org/10.1016/S0210-5705(24)00183-3","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141089885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metástasis de origen pulmonar de localización inusual","authors":"Carmen Pradera Cibreiro , Marta Ramos Alonso , Rafael Lago Cascudo , Martín Fernández López , Diana Alejandra Rivera Castillo , María Violeta Mauriz Barreiro","doi":"10.1016/j.gastrohep.2023.01.004","DOIUrl":"10.1016/j.gastrohep.2023.01.004","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10686980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LPS-TLR4 pathway exaggerates alcoholic hepatitis via provoking NETs formation","authors":"Yang Liu ,&nbsp;Shuo Chen ,&nbsp;Shuo Yu ,&nbsp;Jiazhong Wang ,&nbsp;Xin Zhang ,&nbsp;Hao Lv ,&nbsp;Harouna Aboubacar ,&nbsp;Nan Gao ,&nbsp;Xiaoli Ran ,&nbsp;Yun Sun ,&nbsp;Gang Cao","doi":"10.1016/j.gastrohep.2023.05.002","DOIUrl":"10.1016/j.gastrohep.2023.05.002","url":null,"abstract":"<div><h3>Background</h3><p>Intrahepatic infiltration of neutrophils is a character of alcoholic hepatitis (AH) and neutrophil extracellular traps (NETs) are an important strategy for neutrophils to fix and kill invading microorganisms. The gut-liver axis has been thought to play a critical role in many liver diseases also including AH. However, whether NETs appear in AH and play role in AH is still unsure.</p></div><div><h3>Methods</h3><p><span><span>Serum samples from AH patients were collected and LPS and MPO-DNA were detected. WT, </span>NE KO, and </span>TLR4 KO mice were used to build the AH model, and the intestinal bacteria were eliminated at the same time and LPS was given. Then the formation of NETs and AH-related markers were detected.</p></div><div><h3>Results</h3><p>The serum MPO-DNA and LPS concentration was increased in AH patients and a correlation was revealed between these two indexes. More intrahepatic NETs formed in AH mice. NETs formation decreased with antibiotic intervention and restored with antibiotic intervention plus LPS supplement. While NETs formation failed to change with gut microbiome or combine LPS supplement in TLR4 KO mice. As we tested AH-related characters, liver injury, intrahepatic fat deposition, inflammation, and fibrosis alleviated with depletion of NE. These related marks were also attenuated with gut sterilization by antibiotics and recovered with a combined treatment with antibiotics plus LPS. But the AH-related markers did show a difference in TLR4 KO mice when they received the same treatment.</p></div><div><h3>Conclusion</h3><p>Intestinal-derived LPS promotes NETs formation in AH through the TLR4 pathway and further accelerates the AH process by NETs.</p></div>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9535578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comunicaciones orales. Sesión General 2","authors":"","doi":"10.1016/S0210-5705(24)00176-6","DOIUrl":"https://doi.org/10.1016/S0210-5705(24)00176-6","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141090136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatic cystadenoma as cause of secondary Budd-Chiari syndrome","authors":"David Villaescusa,&nbsp;Miguel Ángel Rodríguez-Gandía,&nbsp;Elena Garrido,&nbsp;Diego Burgos,&nbsp;Julia López,&nbsp;Luis Téllez,&nbsp;José Luis Lledó,&nbsp;Agustín Albillos","doi":"10.1016/j.gastrohep.2023.03.006","DOIUrl":"10.1016/j.gastrohep.2023.03.006","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9292644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comunicaciones orales. Sesión General 6","authors":"","doi":"10.1016/S0210-5705(24)00180-8","DOIUrl":"https://doi.org/10.1016/S0210-5705(24)00180-8","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141089882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Junta directiva y Comité científico","authors":"","doi":"10.1016/S0210-5705(24)00174-2","DOIUrl":"https://doi.org/10.1016/S0210-5705(24)00174-2","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0210570524001742/pdfft?md5=0b20e77c371a41fa5f8133fdd5b60a03&pid=1-s2.0-S0210570524001742-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141090134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comunicaciones orales. Sesión General 1","authors":"","doi":"10.1016/S0210-5705(24)00175-4","DOIUrl":"https://doi.org/10.1016/S0210-5705(24)00175-4","url":null,"abstract":"","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141090135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Documento de consenso de la Sociedad Española de Trasplante Hepático. Recuperación intensificada en trasplante hepático","authors":"Laura Lladó ,&nbsp;Manuel Abradelo de Usera ,&nbsp;Annabel Blasi ,&nbsp;Rosa Gutiérrez ,&nbsp;Eva Montalvá ,&nbsp;Sonia Pascual ,&nbsp;Gonzalo Rodríguez-Laiz ,&nbsp;en representación de la Sociedad Española de Trasplante Hepático (SETH)","doi":"10.1016/j.gastrohep.2023.06.009","DOIUrl":"10.1016/j.gastrohep.2023.06.009","url":null,"abstract":"<div><p>The goal of the Spanish Society for Liver Transplantation (<em>Sociedad Española de Trasplante Hepático</em>) is to promote and create consensus documents about current topics in liver transplantation with a multidisciplinary approach. To this end, in November 2022, the 10th Consensus Document Meeting was held, with the participation of experts from the 26 authorized Spanish liver transplantation programs. This edition discusses enhanced recovery after liver transplantation, dividing needed actions into 3<!--> <!-->periods: preoperative, intraoperative and postoperative. The evaluated evidence and the consensus conclusions for each of these topics are described.</p></div>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139717510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of colorectal cancer screening backlog due to the COVID-19 pandemic: A retrospective analysis of the use of a colorectal cancer screening clinical-decision support tool in Argentina","authors":"Lisandro Pereyra ,&nbsp;Leandro Steinberg ,&nbsp;Juan Lasa ,&nbsp;Agustina Marconi ,&nbsp;Audrey H. Calderwood ,&nbsp;María Pellisé","doi":"10.1016/j.gastrohep.2023.02.010","DOIUrl":"10.1016/j.gastrohep.2023.02.010","url":null,"abstract":"<div><h3>Background</h3><p>The COVID-19 pandemic created a backlog in colorectal cancer (CRC) screening and surveillance colonoscopies. The real impact in Argentina is not fully known.</p></div><div><h3>Goal</h3><p>To estimate the impact of the COVID-19 pandemic on CRC prevention by comparing the number of CRC screening and surveillance consults in a clinical decision support-tool used in Argentina before, during and after pandemic lockdown.</p></div><div><h3>Methods</h3><p>We analyzed data from May 2019 to December 2021 from CaPtyVa, a clinical decision support tool for CRC screening and surveillance. Queries were divided in pre-pandemic (May 2019 to March 2020), lockdown (April 2020 to December 2020), and post-lockdown (January 2021 to December 2021). The number of CRC monthly screening and surveillance visits were compared among the three periods and stratified according to CRC risk.</p></div><div><h3>Results</h3><p>Overall, 27,563 consults were analyzed of which 9035 were screening and 18,528 were surveillance. Pre-pandemic, the median number of screening consults was 346 per month (IQR25–75 280–410). There was a decrease to 156 (80–210)/month (<em>p</em> <!-->&lt;<!--> <!-->0.005) during lockdown that partially recovered during post-lockdown to 230 (170–290)/month (<em>p</em> <!-->=<!--> <!-->0.05). Pre-pandemic, the median number of surveillance consults was 716 (560–880)/month. They decreased to 354 (190–470)/month during lockdown (<em>p</em> <!-->&lt;<!--> <!-->.05) and unlike screening, completely recovered during post-lockdown to 581 (450–790)/month.</p></div><div><h3>Conclusions</h3><p>There was a &gt;50% decrease in the number of CRC screening and surveillance consults registered in CaPtyVa during lockdown in Argentina. Post-lockdown, surveillance consults recovered to pre-pandemic levels, but screening consults remained at 66% of pre-pandemic levels. This has implications for delays in CRC diagnoses and patient outcomes.</p></div>","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9703483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}