Gastroenterologia y hepatologia最新文献_第5页

Disease clearance in ulcerative colitis: What is it? What does it involve? How do we translate it into spanish? 溃疡性结肠炎的疾病清除：它是什么？它包括哪些内容？如何翻译成西班牙语？

IF 2.2 4区医学

Gastroenterologia y hepatologia Pub Date : 2024-10-28 DOI: 10.1016/j.gastrohep.2024.502281

Laura Ramos, Ignacio Marín-Jiménez

引用次数: 0

The impact of anxiety and depression on quality of life in a cohort of inflammatory bowel disease patients from Northeastern of Brazil. 巴西东北部一组炎症性肠病患者的焦虑和抑郁对生活质量的影响。

IF 2.2 4区医学

Gastroenterologia y hepatologia Pub Date : 2024-10-28 DOI: 10.1016/j.gastrohep.2024.502283

Raiza Lima Silva, Francisca Isabelle da Silva E Sousa, Gabriel Lucas Ferreira da Silva, Victória Danielly Rabelo Almeida, Simão Barbosa Silva, Mateus Mendes Santos Freire, Marcellus Henrique Loiola Ponte de Souza, Lucia Libanez Bessa Campelo Braga

{"title":"The impact of anxiety and depression on quality of life in a cohort of inflammatory bowel disease patients from Northeastern of Brazil.","authors":"Raiza Lima Silva, Francisca Isabelle da Silva E Sousa, Gabriel Lucas Ferreira da Silva, Victória Danielly Rabelo Almeida, Simão Barbosa Silva, Mateus Mendes Santos Freire, Marcellus Henrique Loiola Ponte de Souza, Lucia Libanez Bessa Campelo Braga","doi":"10.1016/j.gastrohep.2024.502283","DOIUrl":"10.1016/j.gastrohep.2024.502283","url":null,"abstract":"Objective: This study aims to assess whether the association between chronic pathologies and depressive and/or anxious disorders is high, resulting in a reduction in the patient's quality of life.Patients and methods: This is a prospective cross-sectional study with a descriptive and analytical design. Sociodemographic data and lifestyle habits were collected. Subsequently, the Inflammatory Bowel Disease Questionnaire (IBDQ) and the Hospital Anxiety and Depression Scale (HADS) were applied.Results: A total of 141 patients participated in the study, with a mean age of 45.78 (SD 16.01) years, of which 60.3% were female (n=85) and 39.7% were male (n=56). 58.9% had ulcerative colitis (UC) (n=83), and 41.1% had Crohn's disease (CD) (n=58). 16.5% of patients had a previous diagnosis of generalized anxiety disorder (GAD) and/or major depression (MD) (n=23). Regarding IBDQ scores, participants with anxiety had significantly lower mean scores in all IBDQ items (p<0.001), while the depression diagnosis obtained significantly lower mean values for systemic (p=0.015), emotional (p=0.001), and intestinal symptoms (p=0.005).Conclusion: The results indicate that anxiety and depression negatively impact the quality of life of patients with IBD independently of the disease activity.","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A targeted endoscopic band ligation technique for management of acute esophageal variceal bleeding. 治疗急性食管静脉曲张出血的定向内窥镜带状结扎技术。

IF 2.2 4区医学

Gastroenterologia y hepatologia Pub Date : 2024-10-28 DOI: 10.1016/j.gastrohep.2024.502282

Gilberto Herrera-Quiñones, Raúl Alberto Jiménez-Castillo, Susana Isabel Scharrer, Diego García-Compean, Joel Omar Jaquez-Quintana, Carlos Alejandro Cortez-Hernández, Héctor Jesús Maldonado-Garza, Andres Cardenas, José Alberto González-González

{"title":"A targeted endoscopic band ligation technique for management of acute esophageal variceal bleeding.","authors":"Gilberto Herrera-Quiñones, Raúl Alberto Jiménez-Castillo, Susana Isabel Scharrer, Diego García-Compean, Joel Omar Jaquez-Quintana, Carlos Alejandro Cortez-Hernández, Héctor Jesús Maldonado-Garza, Andres Cardenas, José Alberto González-González","doi":"10.1016/j.gastrohep.2024.502282","DOIUrl":"10.1016/j.gastrohep.2024.502282","url":null,"abstract":"Background/aims: Endoscopic band ligation (EBL) standard therapy is traditionally performed with banding from the distal esophagus upwards. However, esophageal varices (EV) with stigma of recent bleeding are not consistently banded at the first attempt. We aimed to compare conventional banding in acute variceal bleeding (AVB) vs targeted banding of EV in patients with stigma of recent bleeding (white nipple sign).Methods: This case-control study included patients treated in our hospital from December 2016 to September 2019 with endoscopic signs of recent variceal bleeding. The targeted technique involves deploying the first band at the recent bleeding stigmata and then completing the procedure with standard variceal banding technique. The conventional group included patients treated with standard EBL.Results: We analyzed 92 patients, 54 (58.7%) in conventional technique and 38 (41.3%) in the targeted group. Active bleeding during endoscopy occurred in 11 (20.0%) of conventional and two (6.5%) of the targeted group (p=0.021). Although procedure time was longer in the conventional group (24.3min SD 11.58) compared to the targeted group (21.52min SD 8.73) this difference was not significant. One detached band episode was documented in targeted group and none in the conventional group (p=0.418). TIPS were not used during this study due to health system policy. There were no significant differences in mortality, rebleeding or transfusion requirements between groups.Conclusions: The targeted technique for EV with stigma of recent bleeding had a low band detachment incidence and fewer bleeding events during endoscopy, however, the limitations of the study should be considered.","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":"502282"},"PeriodicalIF":2.2,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differences in management of pediatric functional dyspepsia in Spain, a descriptive study by the Working Group on Motility and Functional Gastrointestinal Disorders of SEGHNP. 西班牙小儿功能性消化不良的管理差异，由 SEGHNP 运动和功能性胃肠道疾病工作组进行的一项描述性研究。

IF 2.2 4区医学

Gastroenterologia y hepatologia Pub Date : 2024-10-22 DOI: 10.1016/j.gastrohep.2024.502279

Miguel Ángel Carro Rodríguez, Inmaculada Hidalgo Montes, Carlos Ruiz Hernández, César Sánchez Sánchez, Andrés Bodas Pinedo

引用次数: 0

Comparative evaluation of point of care assay with ELISA techniques for quantifying serum concentrations of ustekinumab in inflammatory bowel disease patients. 用于定量炎症性肠病患者血清中乌司替尼浓度的护理点测定与酶联免疫吸附技术的比较评估

IF 2.2 4区医学

Gastroenterologia y hepatologia Pub Date : 2024-10-21 DOI: 10.1016/j.gastrohep.2024.502277

Carles Iniesta-Navalón, Manuel Ríos-Saorín, Lorena Rentero-Redondo, Rebeca Añez-Castaño, Elena Urbieta-Sanz

{"title":"Comparative evaluation of point of care assay with ELISA techniques for quantifying serum concentrations of ustekinumab in inflammatory bowel disease patients.","authors":"Carles Iniesta-Navalón, Manuel Ríos-Saorín, Lorena Rentero-Redondo, Rebeca Añez-Castaño, Elena Urbieta-Sanz","doi":"10.1016/j.gastrohep.2024.502277","DOIUrl":"10.1016/j.gastrohep.2024.502277","url":null,"abstract":"Objectives: To evaluate the analytical performance and clinical utility of the POC-AFIAS assay in comparison with two ELISA established assays for quantifying serum concentrations of ustekinumab.Methods: A prospective study was conducted. Consecutive serum samples from adult patients undergoing treatment with ustekinumab were collected. Three analytical techniques were compared for the quantification of ustekinumab serum concentrations: the AFIAS-10® POC assay (POC-AFIAS), the Promonitor® ELISA assay (ELISA-PRO), and the ELISA Ridascreen® assay (ELISA-RDSC). Ustekinumab concentrations were evaluated within three therapeutic ranges: <1μg/mL, 1-4.5μg/mL, and >4.5μg/mL. Statistical analysis included Pearson correlation, intra-class correlation coefficient, and Bland-Altman analysis.Results: A total of 104 patients were included in the study. The median ustekinumab concentrations measured were 5.22μg/mL (POC-AFIAS), 3.99μg/mL (ELISA-PRO), and 4.50μg/mL (ELISA-RDSC). Strong correlations were observed between techniques (POC-AFIAS and ELISA-PRO: r=0.921, POC-AFIAS and ELISA-RDSC: r=0.940, ELISA-PRO and ELISA-RDSC: r=0.976). The Bland-Altman analysis revealed a bias difference of 1.81μg/mL between POC-AFIAS and ELISA-PRO, and 1.27μg/mL between POC-AFIAS and ELISA-RDSC. Agreement rates varied by therapeutic range, with the highest agreement observed within the therapeutic range (97.3%) and lower agreement for supra-therapeutic concentrations (74.6%).Conclusion: This study demonstrated that the POC-AFIAS assay provides comparable results to established ELISA techniques for quantifying serum concentrations of ustekinumab, particularly within the therapeutic range. The findings suggest that the POC-AFIAS assay offers a rapid and effective tool for managing ustekinumab therapy in clinical practice.","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142499152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intraductal oncocytic papillary neoplasm of the pancreas. 胰腺导管内癌细胞乳头状肿瘤。

IF 2.2 4区医学

Gastroenterologia y hepatologia Pub Date : 2024-10-19 DOI: 10.1016/j.gastrohep.2024.502278

Guillermo Castillo-López, Santiago González Vázquez, Beatriz Merchán Gómez, Maite Alonso-Sierra, César Prieto de Frías, Fernando Lapuente Sastre, Fernando Rotellar, Carolina Areán Cuns, Pilar López-Ferrer, José María Riesco López

引用次数: 0

Tenofovir alafenamide versus entecavir in treating patients with chronic hepatitis B: A meta-analysis. 治疗慢性乙型肝炎患者的替诺福韦阿拉非酰胺与恩替卡韦：一项荟萃分析。

IF 2.2 4区医学

Gastroenterologia y hepatologia Pub Date : 2024-10-18 DOI: 10.1016/j.gastrohep.2024.502276

Jian-Xing Luo, Guo Chen, Xiao-Yu Hu, Chang Yu

{"title":"Tenofovir alafenamide versus entecavir in treating patients with chronic hepatitis B: A meta-analysis.","authors":"Jian-Xing Luo, Guo Chen, Xiao-Yu Hu, Chang Yu","doi":"10.1016/j.gastrohep.2024.502276","DOIUrl":"10.1016/j.gastrohep.2024.502276","url":null,"abstract":"Background: The superiority between TAF and ETV remains unclear. Which is the best choice for patients with CHB? Thus, this meta-analysis aimed to evaluate the efficacy and safety of TAF and ETV for patients with CHB.Methods: MEDLINE/PubMed, Cochrane Library, EMBASE, Web of Science and CNKI were searched for eligible studies from inception to January 2024 and a meta-analysis was done.Results: 24 trials with a total of 6753 subjects were screened. TAF significantly improved 12- and 24-week complete virological response (CVR), 12-week biochemical response (BR) and 24-week HBeAg loss, but could not improve 48- and 96-week CVR, 24-, 48- and 96-week BR, 96-week HBeAg loss, adverse events, 48-week HBsAg decline and loss, 12-, 24- and 48-week HBeAg seroconversion, 96-week HCC incidence compared to ETV. Subgroup analysis was conducted according to race, research type and switching. Different results were obtained from different subgroups.Conclusions: TAF was superior to ETV at 12- and 24-week CVR, 12-week BR and 24-week HBeAg loss. Race and switching might affect the efficacy of TAF and ETV.","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142463314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The simplified depth-predicting score outperforms the depth-predicting score for predicting the depth of invasion in differentiated early gastric cancer patients among nonexpert endoscopists. 在预测分化型早期胃癌患者的侵犯深度方面，简化深度预测评分优于非专业内镜医师的深度预测评分。

IF 2.2 4区医学

Gastroenterologia y hepatologia Pub Date : 2024-10-11 DOI: 10.1016/j.gastrohep.2024.502265

Lulu Zeng, Hui Li, Tian Huang, Yuting Heng, Jun Liu, Xiangpeng Hu

{"title":"The simplified depth-predicting score outperforms the depth-predicting score for predicting the depth of invasion in differentiated early gastric cancer patients among nonexpert endoscopists.","authors":"Lulu Zeng, Hui Li, Tian Huang, Yuting Heng, Jun Liu, Xiangpeng Hu","doi":"10.1016/j.gastrohep.2024.502265","DOIUrl":"10.1016/j.gastrohep.2024.502265","url":null,"abstract":"Aim: Endoscopists utilize depth-predicting score (DPS) and simplified depth-predicting score (S-DPS) to predict the invasion depth of early gastric cancer based on conventional white-light endoscopic features. The effectiveness of these scores has not been fully elucidated among nonexpert endoscopists. This study aimed to compare the ability of DPS and S-DPS to predict invasion depth of differentiated early gastric cancers by nonexpert endoscopists.Participants and methods: We collected subitem scores of DPS and S-DPS from 19 nonexpert endoscopists for early gastric cancer conventional white-light endoscopy images in the test dataset to predict the invasion depth of the early gastric cancer conventional white-light endoscopy images. Accuracy, specificity, overdiagnosis rate, and underdiagnosis rate were subsequently calculated using the histological invasion depth as the gold standard.Results: Using 3 as the cutoff line, the overall S-DPS diagnostic accuracy for invasion depth was significantly greater than that of DPS [73.86% (69.32%, 75.00%) vs. 67.05% (62.50%, 71.59%), p=0.005]. The overall S-DPS overdiagnosis rate was significantly lower than that of DPS [7.58% (3.03%, 13.64%) vs. 28.79% (18.18%, 37.88%), p=0.000]. The overall S-DPS under-diagnosed rate was significantly higher than that of DPS [86.36% (68.18%, 90.91%) vs. 45.45% (31.82%, 59.09%), p=0.000]. The specificity of the S-DPS was significantly greater than that of DPS [92.42% (86.36%, 96.97%) vs. 71.21% (62.12%, 81.82%), p=0.000].Conclusion: The diagnostic accuracy of the S-DPS was greater than that of the DPS among nonexpert endoscopists. Furthermore, S-DPS is simpler than other methods, making it more conducive to clinical application for nonexpert endoscopists.","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142463315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic characteristics and extracolonic phenotypic manifestations in patients with familiar adenomatous polyposis. 熟悉的腺瘤性息肉病患者的遗传特征和结肠外表型表现。

IF 2.2 4区医学

Gastroenterologia y hepatologia Pub Date : 2024-10-11 DOI: 10.1016/j.gastrohep.2024.502266

Víctor Argumánez, Vicente Lorenzo-Zúñiga, Marco Bustamante-Balén, Sonia García García, Isabel Terol Cháfer, Silvestre Oltra, Vicente Pons-Beltrán

{"title":"Genetic characteristics and extracolonic phenotypic manifestations in patients with familiar adenomatous polyposis.","authors":"Víctor Argumánez, Vicente Lorenzo-Zúñiga, Marco Bustamante-Balén, Sonia García García, Isabel Terol Cháfer, Silvestre Oltra, Vicente Pons-Beltrán","doi":"10.1016/j.gastrohep.2024.502266","DOIUrl":"10.1016/j.gastrohep.2024.502266","url":null,"abstract":"Introduction: Familial adenomatous polyposis (FAP) is a hereditary disease caused by mutations in the APC gene, which is also associated with extracolonic manifestations. The objective was to characterize the extracolonic manifestations in a cohort of patients with classic FAP and the possible genotype-phenotype association.Materials and methods: The study design was observational and descriptive. Demographic, clinical, and genetic variables were collected based on the type of mutation (frameshift, nonsense, splicing, rearrangement, and others).Results: We included 45 patients with FAP (mean age 47years, range 21-78; 51% female), belonging to 21 families, with a median of 2 (range 0-6) manifestations per patient. Eighty percent (n=36) had upper digestive tract involvement, with duodenal adenomas (73%), fundic gland polyposis (56%), and ampullary adenoma (36%) being the most frequent findings. The most common extraintestinal manifestations were desmoid tumors (16%) and papillary thyroid carcinoma (13%). Thirty eight percent of the patients presented an aggressive phenotype (SpigelmanIII-IV, high-grade dysplasia, invasive neoplasia, desmoid tumor, and papillary thyroid carcinoma). The most common genetic mutations were frameshift (56%), nonsense (26%), and splicing (16%), primarily located in exon15 (50%). No significant correlation was found between the type of genetic mutation and the severity or location of phenotypic manifestations.Conclusions: One-third of patients with FAP present an aggressive phenotype, without a demonstrated correlation between the type of genetic alteration and the phenotypic manifestations.","PeriodicalId":12802,"journal":{"name":"Gastroenterologia y hepatologia","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142463312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sustained jaundice after endoscopic retrograde cholangiopancreatography. 内镜逆行胰胆管造影术后持续黄疸。内镜逆行胰胆管造影术后持续黄疸。

IF 2.2 4区医学

Gastroenterologia y hepatologia Pub Date : 2024-10-10 DOI: 10.1016/j.gastrohep.2024.502264

Idoia Agulleiro Beraza, Eduardo Leo Carnerero, José Manuel Sousa Martín, Rose Marie Vallejo Vigo

引用次数: 0