Glycoconjugate Journal最新文献

Editorial Expression of Concern: Disease-associated glycosylated molecular variants of human C-reactive protein activate complement-mediated hemolysis of erythrocytes in tuberculosis and Indian visceral leishmaniasis. 关注的编辑表达：疾病相关的人c反应蛋白糖基化分子变异激活补体介导的红细胞溶血在结核病和印度内脏利什曼病。

IF 3.1 4区生物学

Glycoconjugate Journal Pub Date : 2026-04-27 DOI: 10.1007/s10719-026-10214-4

Waliza Ansar, Sumi Mukhopadhyay, S K Hasan Habib, Shyamasree Basu, Bibhuti Saha, Asish Kumar Sen, C N Mandal, Chitra Mandal

引用次数: 0

N-glycan signatures of immunoglobulins-depleted serum proteins in colorectal cancer. 结直肠癌中免疫球蛋白缺失血清蛋白的n -聚糖特征。

IF 3.1 4区生物学

Glycoconjugate Journal Pub Date : 2026-04-23 DOI: 10.1007/s10719-026-10216-2

Huiai Lu, Yuanyuan Liu, Yi Wang, Jiajing Lin, Liming Cheng, Xin Liu, Si Liu, At

引用次数: 0

The structural units, recognition factors (RFs) and their codes of a LFuc Recognition Protein (FRP)^. LFuc识别蛋白（FRP）的结构单元、识别因子及其编码。

IF 3.1 4区生物学

Glycoconjugate Journal Pub Date : 2026-04-22 DOI: 10.1007/s10719-025-10208-8

Albert M Wu, Tanuja Singh, Jia Hau Liu, Yung Liang Chen

引用次数: 0

De novo determination of fucose linkages in N-glycans using logically derived sequence tandem mass spectrometry. 用逻辑推导的序列串联质谱法从头测定n -聚糖中的焦点键。

IF 3.1 4区生物学

Glycoconjugate Journal Pub Date : 2026-04-21 DOI: 10.1007/s10719-026-10213-5

Jien-Lian Chen, Hsien-Wei Tseng, Chun-Cheng Lin, Chi-Kung Ni

引用次数: 0

GlycoRNA biology, a naive field with unlimited horizons. GlycoRNA生物学，一个有着无限视野的幼稚领域。

IF 3.1 4区生物学

Glycoconjugate Journal Pub Date : 2026-03-16 DOI: 10.1007/s10719-026-10212-6

Amit Ranjan, Rajesh Kumar Gupta

引用次数: 0

Enhanced anti-proliferative activity of Jacalin, a plant lectin in combination with taxol in MDA-MB-468 triple-negative breast cancer cells. 植物凝集素Jacalin联合紫杉醇对MDA-MB-468三阴性乳腺癌细胞的抗增殖活性增强

IF 3.1 4区生物学

Glycoconjugate Journal Pub Date : 2026-03-05 DOI: 10.1007/s10719-026-10210-8

Bommanaboina Anil Kumar, Thaslima B, Lavanya V, Shazia Jamal, Neesar Ahmed

引用次数: 0

Salmon proteoglycan modulates TIMP-gelatinase regulation in intestinal epithelial cells. 三文鱼蛋白多糖调节肠上皮细胞中timp -明胶酶的调节。

IF 3.1 4区生物学

Glycoconjugate Journal Pub Date : 2026-02-13 DOI: 10.1007/s10719-026-10211-7

Shintaro Hirasawa, Tomio Yabe

引用次数: 0

Identification of mitochondrial associated genes as diagnostic biomarkers for basal cell carcinoma: Comprehensive bioinformatics analysis and experimental validation. 鉴定线粒体相关基因作为基底细胞癌的诊断生物标志物：综合生物信息学分析和实验验证。

IF 3.1 4区生物学

Glycoconjugate Journal Pub Date : 2026-02-12 DOI: 10.1007/s10719-026-10209-1

Zuojiao Xu, Chunjun Yang

引用次数: 0

Total plasma N-glycomic patterns of COVID-19 disease. COVID-19疾病的总血浆n -糖糖型。

IF 3.1 4区生物学

Glycoconjugate Journal Pub Date : 2026-01-20 DOI: 10.1007/s10719-025-10201-1

Georgia Elgood-Hunt, Jack Cheeseman, Richard A Gardner, Thomas Sénard, Paulina A Urbanowicz, Alejandro A Garcia Leon, Cormac McCarthy, Marco P Monopoli, Daryl L Fernandes, Craig P Thompson, Oleg A Mayboroda, Patrick W G Mallon, Daniel I R Spencer

{"title":"Total plasma N-glycomic patterns of COVID-19 disease.","authors":"Georgia Elgood-Hunt, Jack Cheeseman, Richard A Gardner, Thomas Sénard, Paulina A Urbanowicz, Alejandro A Garcia Leon, Cormac McCarthy, Marco P Monopoli, Daryl L Fernandes, Craig P Thompson, Oleg A Mayboroda, Patrick W G Mallon, Daniel I R Spencer","doi":"10.1007/s10719-025-10201-1","DOIUrl":"10.1007/s10719-025-10201-1","url":null,"abstract":"Total plasma N-glycans alter in disease states, with few studies focused on COVID-19. A discovery cohort of 310 COVID-19 patients, replicated with 97 COVID-19 patients and tested with 100 COVID-19 patients, was used to unearth the N-glycans capable of distinguishing infection, as well as prognosis of intensive care unit (ICU) admission and mortality. All significant bisected glycans were decreased in patients compared to controls, whilst fucosylated tri-antennary glycans and sialylated tetra-antennary glycans were increased in patients. For both those admitted to the ICU and those who died, Peak 61 (A4G4S4F) was elevated in the more severe disease course, while Peak 29 (FA2G2S2) was lowered. Pinpointing specific glycosylation changes has alluded to a potential story of glycoprotein pathways in response to SARS-CoV-2 infection. This study could be further explored through deriving the glycoproteins associated with the glycans of interest and the glycosylation changes experienced on these proteins.","PeriodicalId":12762,"journal":{"name":"Glycoconjugate Journal","volume":"43 1","pages":"9"},"PeriodicalIF":3.1,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12819545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146009651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Isolation and structural elucidation of immunomodulatory oligosaccharides from Trillium tschonoskii. 黄芩免疫调节寡糖的分离与结构分析。

IF 3.1 4区生物学

Glycoconjugate Journal Pub Date : 2026-01-12 DOI: 10.1007/s10719-025-10204-y

Juan Song, Si Liu, Meng Sun, Guangzhong Tu, Zhiqiang Zhang, Yue Liu, Yi Nan, Guobin Shen, Xiaojuan Chen, Haizhen Liang, Bin Liu, Baiping Ma

{"title":"Isolation and structural elucidation of immunomodulatory oligosaccharides from Trillium tschonoskii.","authors":"Juan Song, Si Liu, Meng Sun, Guangzhong Tu, Zhiqiang Zhang, Yue Liu, Yi Nan, Guobin Shen, Xiaojuan Chen, Haizhen Liang, Bin Liu, Baiping Ma","doi":"10.1007/s10719-025-10204-y","DOIUrl":"https://doi.org/10.1007/s10719-025-10204-y","url":null,"abstract":"Six oligosaccharides with the degree of polymerization (DP) 2 to 7 were isolated from the active fraction of Trillium tschonoskii using a high-temperature semi-preparative porous graphitic carbon (PGC) column based on high-performance liquid chromatography coupled with a charged aerosol detector and vanquish fraction collector (HPLC-CAD-VFC) system. The structures of DP2 - 7 were determined as maltose, maltotriose, maltotetraose, maltopentaose, maltohexaose, and maltoheptaose with (1→4)-α-D-glucopyranose residues by relative quantitative 1H nuclear magnetic resonance (qHNMR) spectroscopy with anomeric protons integration and NMR structural-reporter-group resonances. The immunomodulatory activities of this series of maltooligosaccharides (MOS) were tested on RAW264.7 cells. All samples on cells had no cytotoxicity, and the oligosaccharide fraction (TOS1) could increase the phagocytic capacity and production of nitric oxide (NO) and cytokines to a much higher level than monomers. In particular, maltopentaose (DP5) showed a relatively higher capacity for stimulating proliferation, NO, and cytokine production than other purified oligosaccharides. The immunomodulatory activity of MOS investigated in this study is beneficial for utilizing MOS as a functional ingredient in novel product development.","PeriodicalId":12762,"journal":{"name":"Glycoconjugate Journal","volume":"43 1","pages":"8"},"PeriodicalIF":3.1,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145951785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0