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Prevalence of Elder Abuse and Neglect of Persons with Dementia in Community Settings: A Systematic Review and Meta-Analysis. 社区环境中对老年痴呆症患者的虐待和忽视:一项系统回顾和荟萃分析。
IF 3.1 3区 医学
Gerontology Pub Date : 2025-01-01 Epub Date: 2025-03-28 DOI: 10.1159/000543804
Yan Shen, Fei Sun, Yali Feng, Peter A Lichtenberg, Hongdao Meng
{"title":"Prevalence of Elder Abuse and Neglect of Persons with Dementia in Community Settings: A Systematic Review and Meta-Analysis.","authors":"Yan Shen, Fei Sun, Yali Feng, Peter A Lichtenberg, Hongdao Meng","doi":"10.1159/000543804","DOIUrl":"10.1159/000543804","url":null,"abstract":"<p><strong>Introduction: </strong>Individuals with dementia are at an elevated risk for abuse and neglect. This study aimed to estimate pooled prevalence rates of elder abuse among community-dwelling individuals with dementia using a meta-analytic approach. Additionally, it explored the heterogeneity associated with prevalence estimates through subgroup analyses.</p><p><strong>Methods: </strong>In line with the Cochrane guidelines, searches were conducted across eight academic online databases, reference lists of eligible studies, and existing systematic reviews. Eligible studies are studies published between January 1990 and March 2023 that report elder abuse among people with dementia (PWD) in community settings. The final review included 30 eligible studies from eight countries, encompassing a sample of 6,789 dependent/carer dyads.</p><p><strong>Results: </strong>The pooled rate of overall abuse among older adults with dementia is 42.6% (95% CI: 0.34-0.51). Among the various forms of abuse, psychological abuse was most prevalent, occurring in 44.8% of cases (95% CI: 0.37, 0.52), followed by financial abuse (28.3%, 95% CI: 0.03, 0.53), neglect (19.8%, 95% CI: 0.09, 0.34), and physical abuse (10%, 95% CI: 0.07, 0.13).</p><p><strong>Conclusion: </strong>The high prevalence of elder abuse highlights the significant vulnerability of individuals with dementia. The highest rate of psychological abuse indicates a particular need to address emotional trauma of PWD, as well as to adopt measures to reduce abusive or neglectful behaviors via caregiver education and support.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":"71 5","pages":"400-416"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychological Effects of Mountainous Environments over the Life Span and Potential Implications for Healthy Ageing: A Narrative Review. 山区环境对生命周期的心理影响及其对健康老龄化的潜在影响:叙述性综述。
IF 3.1 3区 医学
Gerontology Pub Date : 2025-01-01 Epub Date: 2025-05-21 DOI: 10.1159/000546367
Benedikt Hösl, Martin Niedermeier, Johannes Burtscher, Martin Kopp
{"title":"Psychological Effects of Mountainous Environments over the Life Span and Potential Implications for Healthy Ageing: A Narrative Review.","authors":"Benedikt Hösl, Martin Niedermeier, Johannes Burtscher, Martin Kopp","doi":"10.1159/000546367","DOIUrl":"10.1159/000546367","url":null,"abstract":"<p><strong>Background: </strong>Healthy ageing is defined as a process of preserving functional capacity to enable well-being in old age. This concept includes both a physical and a psychological component, which can be positively influenced by spending time in nature and being physically active. Mountainous areas offer diverse opportunities to be physically active in a natural environment. However, little research is available on the psychological effects of mountain environments and mountain sports, particularly in relation to healthy ageing.</p><p><strong>Summary: </strong>We analyse the extent to which the interactions of physical activity, nature exposure, and specific characteristics of mountainous regions including hypoxia may influence mental health, based on current research, and discuss the relevance of these factors individually and in combination for healthy ageing.</p><p><strong>Key messages: </strong>In general, the benefits reported from spending time in nature or physical activity seem to be transferable to mountainous regions and/or mountain sports. The available research primarily points to positive acute and longer-term psychological (and sometimes therapeutic) effects of exposure to mountainous regions and mountain sports performed in moderate altitude on various mental health parameters, such as well-being, anxiety, and depression, which could in turn promote healthy ageing. In contrast, staying at very high or extremely high altitudes seems to be associated with negative effects on mental health. Overall, further research is needed to draw more reliable conclusions.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"546-554"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trajectories of Instrumental Activities of Daily Living and Their Predictors among Older Men and Women in Hong Kong: A 14-Year Prospective Study. 香港老年男女日常生活工具活动轨迹及其预测因素:一项为期14年的前瞻性研究。
IF 3.1 3区 医学
Gerontology Pub Date : 2025-01-01 Epub Date: 2025-01-02 DOI: 10.1159/000543378
Zhihui Lu, Jason Leung, T W Auyeung, Jenny Lee, Kenneth Lo, King-Son Lai, Kuen Lam, Jean Woo, Timothy Kwok
{"title":"Trajectories of Instrumental Activities of Daily Living and Their Predictors among Older Men and Women in Hong Kong: A 14-Year Prospective Study.","authors":"Zhihui Lu, Jason Leung, T W Auyeung, Jenny Lee, Kenneth Lo, King-Son Lai, Kuen Lam, Jean Woo, Timothy Kwok","doi":"10.1159/000543378","DOIUrl":"10.1159/000543378","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to identify the different patterns of trajectories in instrumental activities of daily living (IADL) in older men and women, respectively, and to examine the factors associated with the different trajectories.</p><p><strong>Methods: </strong>We included 2,088 participants with an average age of 70.8 years at baseline from the MrOS and MsOS Hong Kong cohort study (men: 1,074; women: 1,014) and followed up the participants for over 14 years. The group-based trajectory models were used to identify IADL trajectories. Binary logistic regression and multinominal logistic regression models were used to identify factors associated with different trajectories.</p><p><strong>Results: </strong>Two distinct trajectories were identified for men including \"slow decliners\" (92.6% of men) and \"rapid decliners\" (7.4%), while three distinct trajectories were identified for women including \"slow decliners\" (43.5% of women), \"intermediate decliners\" (48.2%), and \"rapid decliners\" (8.3%). Being overweight or obese and slow walking speed were common predictors of more rapid IADL declining trajectories in both men and women. Particularly, having stroke, weak grip strength, and higher level of PM2.5 were associated with the higher risk of being rapid decliners in men, and having osteoporosis and poor self-rated health were associated with more rapid IADL declining trajectories in women.</p><p><strong>Conclusion: </strong>Sex differences were observed in the IADL declining trajectories. Several risk factors were found that could possibly be useful in identifying and preventing functional impairments in an earlier stage.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":"71 2","pages":"81-87"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11854970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Engagement in the Community-Based Going-Out Programs and the Association with Physical Frailty Assessed by the Kihon Checklist: A Cohort Study. 参与以社区为基础的外出活动与Kihon检查表评估的身体虚弱的关系:一项队列研究。
IF 3.1 3区 医学
Gerontology Pub Date : 2024-12-02 DOI: 10.1159/000542089
Masanori Morikawa, Kenji Harada, Satoshi Kurita, Chiharu Nishijima, Kazuya Fujii, Daisuke Kakita, Yukari Yamashiro, Naoto Takayanagi, Motoki Sudo, Hiroyuki Shimada
{"title":"Engagement in the Community-Based Going-Out Programs and the Association with Physical Frailty Assessed by the Kihon Checklist: A Cohort Study.","authors":"Masanori Morikawa, Kenji Harada, Satoshi Kurita, Chiharu Nishijima, Kazuya Fujii, Daisuke Kakita, Yukari Yamashiro, Naoto Takayanagi, Motoki Sudo, Hiroyuki Shimada","doi":"10.1159/000542089","DOIUrl":"10.1159/000542089","url":null,"abstract":"<p><strong>Introduction: </strong>In efforts to address the public health concern of physical frailty prevention, community-based programs without supervision are anticipated, yet efficacy has not been shown. We aimed to investigate the association of engaging in an unsupervised, community-based going-out program on the incidence of physical frailty among older adults.</p><p><strong>Methods: </strong>A cohort observational study was employed. Following a baseline assessment during 2015 and 2017 in Japan, we observed 1,350 older adults engage in a community-based going-out program for 12 months. Participants were categorized into either a non-engaged or engaged group via propensity score matching. A follow-up survey (mean period = 920 ± 76 days) was conducted to investigate the occurrence of physical frailty using the Kihon Checklist. The incidence of frailty, absolute risk reduction, and number needed to treat for program engagement were calculated. The odds ratio (OR) in engaged group compared with the non-engaged group was determined in a logistic regression model.</p><p><strong>Results: </strong>Incidence of frailty was 15.1% in non-engaged group (n = 107 out of 628) and 8.3% in the engaged group (n = 53 out of 628). The number needed to treat and its 95% confidence interval were 21 (12-63) after matching. Compared with matched non-engaged group (OR 1.0), the OR and 95% confidence interval of matched engaged group for occurrence of physical frailty were 0.61 (0.42-0.87).</p><p><strong>Conclusions: </strong>Engaging in the unsupervised community-based going-out program could prevent one incidence of physical frailty in every 21 participants and may thus contribute to preventing physical frailty at the population level.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-11"},"PeriodicalIF":3.1,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142768329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic Nf-κB Inhibition Prevents Experimental Aging Nephropathy. 慢性 Nf-κB 抑制可预防实验性衰老性肾病
IF 3.1 3区 医学
Gerontology Pub Date : 2024-11-27 DOI: 10.1159/000540761
Helena Mendonça Tessaro, Fernanda Florencia Fregnan Zambom, Orestes Foresto-Neto, Sara Cristina Fim Ribeiro, Claudia Ramos de Sena, Denise Maria Avancini Costa Malheiros, Niels Olsen Saraiva Câmara, Clarice Kazue Fujihara, Roberto Zatz
{"title":"Chronic Nf-κB Inhibition Prevents Experimental Aging Nephropathy.","authors":"Helena Mendonça Tessaro, Fernanda Florencia Fregnan Zambom, Orestes Foresto-Neto, Sara Cristina Fim Ribeiro, Claudia Ramos de Sena, Denise Maria Avancini Costa Malheiros, Niels Olsen Saraiva Câmara, Clarice Kazue Fujihara, Roberto Zatz","doi":"10.1159/000540761","DOIUrl":"https://doi.org/10.1159/000540761","url":null,"abstract":"<p><p>Introduction The pathogenesis of aging nephropathy is yet to be elucidated. Intrarenal Angiotensin-II (AngII) and activation of the NF-κB and NLRP3 inflammasome pathways exert a relevant pathogenic role in the progression of chronic kidney disease (CKD). We sought to investigate whether monotherapy with Losartan and combined treatment with Losartan and the NF-κB inhibitor pyrrolidine dithiocarbamate (PDTC) would attenuate experimental aging nephropathy. Materials and Methods Forty adult Male Munich-Wistar rats were distributed among four groups: 12M (n=10), untreated 12-month-old rats; 15M (n=10), untreated 15-month-old rats; 15MLos (n=8), rats receiving Losartan (50 mg/kg/d) and 15MLos+PDTC (n=8), rats receiving Losartan and PDTC (60 mg/kg/d). All treatments were given by mouth from 12 to 15 months of age. Results Group 15M exhibited slightly decreased tail-cuff pressure, and marked increase in albuminuria, sclerotic glomeruli, cortical collagen-1 deposition and infiltration by myofibroblasts, AngII-positive cells and proinflammatory M1 macrophages, whereas the amount of anti-inflammatory M2 macrophages was reduced. In addition, the renal abundance of TLR4, nuclear p65 and IL-6 was increased, indicating activation of the NF-κB pathway, without evidence of simultaneous activation of the NLRP3 cascade. Losartan treatment decreased cortical collagen-1 deposition, myofibroblasts and AngII-positive cells, and partially restored renal M2, but had no significant effect on albuminuria, glomerulosclerosis or NF-κB activation. Combined Losartan+PDTC prevented all the observed abnormalities. Discussion/conclusion Simultaneous blockade of renal AngII and inhibition of the NF-κB pathway may represent a novel alternative to limit the decline of renal function with age.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-23"},"PeriodicalIF":3.1,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does the digital divide accelerate cognitive function decline related to the poor management of diabetes in later life? 数字鸿沟是否会加速与晚年糖尿病管理不善有关的认知功能衰退?
IF 3.1 3区 医学
Gerontology Pub Date : 2024-11-25 DOI: 10.1159/000541150
Yanan Luo, Binbin Su, Feiran Zheng, Xiaoying Zheng
{"title":"Does the digital divide accelerate cognitive function decline related to the poor management of diabetes in later life?","authors":"Yanan Luo, Binbin Su, Feiran Zheng, Xiaoying Zheng","doi":"10.1159/000541150","DOIUrl":"https://doi.org/10.1159/000541150","url":null,"abstract":"<p><strong>Introduction: </strong>The objective is to investigate the role of digital exclusion in the association between diabetes and cognitive function among adults aged 50 and above.</p><p><strong>Methods: </strong>107,188 participants aged 50 years old and above across 31 countries from 2010-2018 were involved. The mixed-effects linear regression models were used to analyze the data.</p><p><strong>Results: </strong>The presence of diabetes was found to be associated with a notable reduction in the global cognitive function score (unadjusted β=-0.27, 95% CI: -0.28, -0.25). The presence of digital exclusion was found to have a significant association with the decline in cognitive function scores related to diabetes. Similar trends were observed in the scores for memory, numeracy, and orientation.</p><p><strong>Discussion: </strong>These findings underscore the importance of addressing the digital divide to promote healthy aging. Developing digital interventions targeting diabetes-related cognitive impairments and fostering digital inclusion among older adults with diabetes hold significant value in preventing cognitive impairment.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-15"},"PeriodicalIF":3.1,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Age-Related Hearing Loss: A Cross-Sectional Study of Healthy Older Australians. 与年龄相关的听力损失:对澳大利亚健康老年人的横断面研究。
IF 3.1 3区 医学
Gerontology Pub Date : 2024-11-21 DOI: 10.1159/000541895
Carlene J Britt, Elsdon Storey, Robyn L Woods, Nigel Stocks, Mark R Nelson, Anne M Murray, Joanne Ryan, Gary Rance, John J McNeil
{"title":"Age-Related Hearing Loss: A Cross-Sectional Study of Healthy Older Australians.","authors":"Carlene J Britt, Elsdon Storey, Robyn L Woods, Nigel Stocks, Mark R Nelson, Anne M Murray, Joanne Ryan, Gary Rance, John J McNeil","doi":"10.1159/000541895","DOIUrl":"10.1159/000541895","url":null,"abstract":"<p><strong>Introduction: </strong>Hearing loss is common in ageing populations, but thorough investigation of factors associated with objective hearing loss in otherwise healthy, community-dwelling older individuals is rare. We examined prevalence of age-related hearing loss (ARHL) in healthy, community-dwelling older adults, and determined whether sociodemographic, lifestyle, or health factors associate with hearing thresholds. Audiometry assessment was investigated with self-reports of hearing loss and hearing handicap.</p><p><strong>Methods: </strong>Australian participants (n = 1,260) of median age 73 years (IQR 71-76) joined ASPirin in Reducing Events in the Elderly (ASPREE)-Hearing, a sub-study of the ASPREE trial with exclusions including cognitive impairment, cardiovascular disease, independence-limiting physical disability, and uncontrolled hypertension. ASPREE collected demographics, anthropometrics, lifestyle, and health data. Audiometry measured better ear pure-tone average (PTA) across four frequencies (0.5-4 kHz) to establish hearing thresholds, categorised as normal or mild, moderate, and severe hearing loss. Questionnaires collected perceived hearing problems and noise exposure.</p><p><strong>Results: </strong>ARHL prevalence by audiometry was 49.7%, affecting men (59%) more than women (41%). A majority (54.5%) self-reported some hearing problems which mostly aligned with objective assessments; 45.6% self-reported a \"little trouble\" with hearing, while 35% had objective mild hearing loss; 8.3% reported having a \"lot of trouble\" hearing, while 13% had moderate hearing loss; and 0.6% reported being \"deaf,\" while 2% demonstrated severe hearing loss. There was a significant association (p < 0.001) between self-reported hearing handicap and audiometric measures of hearing loss. In multivariate analysis of health, demographics, and lifestyle risk factors, only age, gender (men), and education years (<12) remained associated (p < 0.05) with hearing loss. Hearing thresholds were not associated with smoking, living situation, alcohol use, hypertension, diabetes, or chronic kidney disease.</p><p><strong>Conclusion: </strong>ARHL robustly assessed by audiometry is common among healthy older Australians with men more likely to have abnormal hearing thresholds than women. Hearing loss was associated with fewer years of formal education, but not with a range of chronic conditions or alcohol use. Self-reported hearing loss correlates well with higher PTA hearing threshold levels in this healthy cohort where prevalence was lower than previously reported for the age group 70+ years. Hearing health education remains an important public health tool for this age. Targeting hearing in older patient health checks could be beneficial to mitigate the cognitive, social, and mental health consequences of ARHL, even if patients do not report a problem or handicap.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-12"},"PeriodicalIF":3.1,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11854973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142686792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Decreased phagocytosis and intracellular killing of bacteria in leukocytes of geriatric patients with Clostridioides difficile infections. 难辨梭状芽孢杆菌感染的老年患者白细胞吞噬能力和细胞内杀灭细菌能力下降。
IF 3.5 3区 医学
Gerontology Pub Date : 2024-09-18 DOI: 10.1159/000541244
Jana Seele,Kaya S Heinen,Volker Meier,Melissa Ballüer,Ellea Liedtke,Marija Djukic,Helmut Eiffert,Roland Nau
{"title":"Decreased phagocytosis and intracellular killing of bacteria in leukocytes of geriatric patients with Clostridioides difficile infections.","authors":"Jana Seele,Kaya S Heinen,Volker Meier,Melissa Ballüer,Ellea Liedtke,Marija Djukic,Helmut Eiffert,Roland Nau","doi":"10.1159/000541244","DOIUrl":"https://doi.org/10.1159/000541244","url":null,"abstract":"INTRODUCTIONPatients suffering from a Clostridioides (C.) difficile infection have a higher overall mortality than patients with similar co-morbidities.METHODSWhole blood samples of 15 patients with C. difficile enteritis and 15 control patients matched for age and sex were used to analyse the capacity of blood phagocytes to internalize and kill encapsulated Escherichia (E.) coli. The median age of C. difficile patients and control patients was 81 and 82 years, respectively. Blood samples were co-incubated with E. coli for 15 or 30min. After 15min of co-incubation, extracellular bacteria were killed by gentamicin for 15-45 minutes. Then eukaryotic cells were lysed with distilled water, and the number of intracellular bacteria per ml whole blood was determined by quantitative plating on agar plates. Both groups were compared by Mann-Whitney U-test.RESULTSAfter 15 or 30min of co-incubation, blood phagocytes from patients with C. difficile enteritis showed a reduced density of phagocytosed or adherent bacteria in comparison to blood phagocytes from control patients (15min: p=0.046, 30min: p=0.005). The density of intracellular bacteria decreased less rapidly over time in the blood from C. difficile patients [median Δlog CFU/ml x h (25th/ 75th percentile) -0.893 (-1.893/ -0.554) versus -1.483 (-2.509/ -1.028); p=0.02]. In line with these results, the percentage of intracellularly killed bacteria was decreased in phagocytes from C. difficile-infected patients compared to controls (median intracellular killing rate 64.3% for blood phagocytes from C. difficile patients versus 81.9% for blood phagocytes from control patients within 30 min of co-incubation, p = 0.048).CONCLUSIONBlood phagocytes from patients with C. difficile enteritis exhibited a reduced capacity to phagocytose and kill bacteria in comparison to blood phagocytes from age- and sex-matched control patients. Patients with C. difficile infection may have a higher disposition to develop infectious diseases than age- and sex-matched control patients.","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":"3 1","pages":"1-12"},"PeriodicalIF":3.5,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142250464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A SIMPLE FRAILTY INDEX PREDICTS IN-HOSPITAL MORTALITY. 简单的虚弱指数可预测住院死亡率。
IF 3.5 3区 医学
Gerontology Pub Date : 2024-09-11 DOI: 10.1159/000541397
Zvi Shimoni,Natan Dusseldorp,Yael Cohen,Izack Barnisan,Paul Froom
{"title":"A SIMPLE FRAILTY INDEX PREDICTS IN-HOSPITAL MORTALITY.","authors":"Zvi Shimoni,Natan Dusseldorp,Yael Cohen,Izack Barnisan,Paul Froom","doi":"10.1159/000541397","DOIUrl":"https://doi.org/10.1159/000541397","url":null,"abstract":"INTRODUCTIONComparing frailty models in different settings that predict in-hospital mortality might modify patient disposition and treatment, but models are often complex.METHODSIn the following study we selected all acutely admitted adult patients in 2020- 2021 to the three internal medicine departments at a regional 400-bed hospital. We attempt to determine (a) if a new scale (Laniado-4 scale) that includes only three yes/no questions derived from the Norton scale and the presence of a urinary catheter performs as well as the graded Norton scale (including all five domains), in predicting in-hospital mortality and (b) to determine the predictive value of a simple frailty index that includes the new scale as well as categories of age, serum albumin, and creatinine values. We calculated odds ratios with 95% confidence intervals and c-statistics for the various models predicting in-hospital mortality.RESULTSThe mean patient age was 73±19 years, and 49.1% (5665/11542) were males. A Laniado-4 scale performed better than the Norton scale for predicting in-hospital mortality. A simple frailty index ranging from 0 to ≥8 points was associated with rates of in-hospital mortality that increased from 0 to 37.7%, with an odds ratio of 2.13(2.03-2.25) per 1 index point. The c-statistic was 0.887 (0.881-0.893).CONCLUSIONSWe conclude the Laniado-4 scale performed better than the Norton scale in predicting in-hospital mortality and that a simple frailty index that included the 4-question scale and categories of age, serum creatinine, and serum albumin performed as well or better than more complicated models.","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":"2021 1","pages":"1-11"},"PeriodicalIF":3.5,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expecting Relocation to a Nursing Home: Longitudinal Links with Functional Limitations, Self-Rated Health, and Life Satisfaction. 预期搬迁到养老院:与功能限制、自我健康评价和生活满意度的纵向联系。
IF 3.5 3区 医学
Gerontology Pub Date : 2024-09-10 DOI: 10.1159/000541336
Emmie A M Verspeek,Yvonne Brehmer,Joran Jongerling,Alexandra Hering,Manon A van Scheppingen
{"title":"Expecting Relocation to a Nursing Home: Longitudinal Links with Functional Limitations, Self-Rated Health, and Life Satisfaction.","authors":"Emmie A M Verspeek,Yvonne Brehmer,Joran Jongerling,Alexandra Hering,Manon A van Scheppingen","doi":"10.1159/000541336","DOIUrl":"https://doi.org/10.1159/000541336","url":null,"abstract":"INTRODUCTIONDeveloping realistic expectations of future old age constitutes an adaptational process which facilitates the anticipation of- and adjustment to challenges, such as relocation to a nursing home. Developing such expectations might minimize negative impacts of relocation. This pre-registered study examined (a) to which extent lower levels and declines in health (i.e., functional limitations and self-rated health) and life satisfaction before relocation were associated with higher levels and increases in expectations to relocate, and (b) to which extent higher expectations to relocate were associated with more positive changes in health and life satisfaction after relocation.METHODSUsing data from the Health and Retirement Study (HRS; 2006-2018), we selected older adults (aged 65 years and older) who relocated to a nursing home. We used latent growth curve models (LGMs) to assess the longitudinal links between self-reported measures of health, life satisfaction, and expectations to relocate to a nursing home from up to seven years before (n = 1,048) until up to five years after relocation (n = 307).RESULTSAs hypothesized, more functional limitations and lower self-rated health were related to higher expectations of relocation. Surprisingly, changes in expectations to relocate were not related to changes in health and life satisfaction before relocation. Moreover, expectations to relocate were not associated with changes in health and life satisfaction after relocation.CONCLUSIONThe absence of a link between expectations to relocate to a nursing home with changes in health and well-being suggests that these expectations did not constitute adaptational processes before or after this transition.","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":"24 1","pages":"1-19"},"PeriodicalIF":3.5,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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