GerontologyPub Date : 2025-01-01Epub Date: 2025-01-27DOI: 10.1159/000543805
Patrick Klaiber, Theresa Pauly
{"title":"Daily Fluctuations in Subjective Age among Older Adults: Links with Stressors, Positive Events, and Emotional Reactions.","authors":"Patrick Klaiber, Theresa Pauly","doi":"10.1159/000543805","DOIUrl":"10.1159/000543805","url":null,"abstract":"<p><strong>Introduction: </strong>Subjective age, or felt age, refers to individuals' perception of their age compared to their chronological age. Feeling older than usual has been associated with experiencing more same-day stressors and higher negative affect. Feeling older may indicate depleted psychological resources, increasing the likelihood of interpreting everyday situations as stressful and reacting more intensely to them. Conversely, feeling younger may indicate greater psychosocial resources, enhancing engagement in and responsiveness to positive events.</p><p><strong>Methods: </strong>This study investigated fluctuations in subjective age as a predictor of same-day event occurrence (stressors and positive events) and affective responses to these events using 14-day diary data from a sample of 108 older Swiss adults (aged 65-92).</p><p><strong>Results: </strong>On average, participants felt approximately 8 years younger than their chronological age, with significant day-to-day variability (ICC = 0.69). On days when individuals felt older than usual, they reported more stressors and fewer positive events. Older subjective age was also associated with greater stress reactivity (greater upticks in negative affect and greater dips in positive affect) and more pronounced responses to positive events. Time-ordered effects showed subjective age predicting positive events, but not stressors.</p><p><strong>Conclusion: </strong>These findings underscore the importance of subjective age as a dynamic psychological construct potentially shaping the events people encounter and how they affectively respond to them. In addition, the lagged analyses provide evidence for subjective age as a predictor of daily event processes, but not for daily events as predictors of future subjective age, which contributes to disentangling the direction of association.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":"71 3","pages":"239-251"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GerontologyPub Date : 2025-01-01Epub Date: 2025-05-02DOI: 10.1159/000546192
Elan Small, Deborah Thomas, Lake Crawford, Isabelle Chatroux, Harrison Steins, Moses Asori, Ben Honigman
{"title":"The Impact of Living at Moderate Altitude in the USA: Epidemiology and Key Research Questions.","authors":"Elan Small, Deborah Thomas, Lake Crawford, Isabelle Chatroux, Harrison Steins, Moses Asori, Ben Honigman","doi":"10.1159/000546192","DOIUrl":"10.1159/000546192","url":null,"abstract":"<p><strong>Background: </strong>Over the last 20 years, the USA has seen a significant population migration into moderate elevation locations (defined as elevations 1,800-2,500 m for the purposes of this review). While considerable research has investigated how chronic diseases are impacted on acute ascent to high altitude, little research has examined how residing at high altitude impacts longer term health including risk of various disease states and long-term morbidity, with even fewer studies examining moderate altitude specifically.</p><p><strong>Summary: </strong>This review investigated how living at moderate elevation impacts seven different disease states/health issues pertinent to the aging individual. Overall, this review reveals a limited literature in this field, though with interesting findings that warrant the need for further studies. While limited studies have documented a potential protective effect of moderate altitude on ischemic heart disease and obesity prevalence, current evidence suggests worse outcomes for chronic obstructive pulmonary disease, possibly increased rates of pulmonary hypertension and low birth weight (which increases risk of chronic diseases later in life), negative impacts on sleep, and increased association with risk of mental health issues including suicide.</p><p><strong>Key messages: </strong>Residing at moderate altitude appears to be beneficial for some disease states but detrimental to others. Further research is needed to solidify these associations, particularly for aging populations, and more importantly to understand the mechanisms that might explain these associations. Understanding the role of mild hypoxia in health resulting from living at moderate altitudes guides improved care delivery and the design of public health interventions.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"535-545"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GerontologyPub Date : 2025-01-01Epub Date: 2025-04-22DOI: 10.1159/000545939
Seyda Bilgin, Veysel Suzan, Bahar Bektan Kanat, Gulru Ulugerger Avci, Suna Avci, Hakan Yavuzer, Ibrahim Murat Bolayırlı, Alper Doventas, Deniz Suna Erdincler
{"title":"Exploring the Relationship between Primary Sarcopenia and Intestinal Barrier Dysfunction in Geriatric Patients: Insights from SARC-F, Serum DAO, Zonulin, LPS, and I-FABP Levels.","authors":"Seyda Bilgin, Veysel Suzan, Bahar Bektan Kanat, Gulru Ulugerger Avci, Suna Avci, Hakan Yavuzer, Ibrahim Murat Bolayırlı, Alper Doventas, Deniz Suna Erdincler","doi":"10.1159/000545939","DOIUrl":"10.1159/000545939","url":null,"abstract":"<p><strong>Introduction: </strong>Objectives of this study were to assess the correlation between serum levels of DAO (diamine oxidase), LPS (lipopolysaccharide), I-FABP (intestinal fatty acid binding protein), and zonulin with primary sarcopenia in elderly patients and to compare the diagnostic performance of these biomarkers with the SARC-F score.</p><p><strong>Methods: </strong>The study included 88 patients aged 65 and above. Comorbidities and geriatric syndromes were assessed, and those with secondary sarcopenia were excluded. The EWGSOP2 criteria were applied for diagnosing sarcopenia, while the SARC-F questionnaire was utilized to identify individuals at risk of sarcopenia. Serum levels of DAO, zonulin, LPS, and I-FABP were measured using ELISA.</p><p><strong>Results: </strong>No significant differences were observed between the two groups regarding age and gender. SARC-F, serum DAO, and zonulin concentrations were notably higher in the sarcopenia group than in the non-sarcopenia group (p < 0.001). Statistically significant parameters were analyzed using stepwise multiple regression. In stepwise multivariate logistic regression analysis, both DAO and zonulin scores were found to be associated with sarcopenia (odds ratio [OR] 1.041, 95% confidence interval [CI]: 1.020-1.063, p < 0.001; OR 1.108, 95% CI: 1.018-1.206, p = 0.018, subsequently). ROC curve analysis revealed that the area under the curve for DAO, zonulin, and SARC-F was 0.807 (p < 0.001), 0.723 (p < 0.001), and 0.943 (p < 0.001), subsequently. The Spearman correlation test revealed a significant, low correlation between serum zonulin and the SARC-F score (r = 0.3583, p = 0.0006) and a moderate correlation between serum DAO and the SARC-F score (r = 0.4384, p < 0.0001).</p><p><strong>Conclusion: </strong>This study is the first to show a connection between primary sarcopenia and intestinal barrier dysfunction. While the findings support the use of the SARC-F questionnaire in routine practice, serum levels of DAO and zonulin could serve as an alternative when the SARC-F questionnaire is not applicable.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"513-523"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GerontologyPub Date : 2025-01-01Epub Date: 2025-05-26DOI: 10.1159/000546478
Johannes Burtscher, Kamilla Woznica Miskowiak, Katharina Hüfner, Hannelore Ehrenreich, Martin Kopp
{"title":"The Potential Role of Mitochondria in Age-Related Health Benefits Conferred by Moderate Hypoxia.","authors":"Johannes Burtscher, Kamilla Woznica Miskowiak, Katharina Hüfner, Hannelore Ehrenreich, Martin Kopp","doi":"10.1159/000546478","DOIUrl":"10.1159/000546478","url":null,"abstract":"<p><strong>Background: </strong>Mitochondrial integrity and efficiency deteriorate with age and are linked to cellular senescence. Mitochondria are highly responsive to reduced oxygen availability (hypoxia), which, e.g., occurs when exposed to altitude. We hypothesize that mitochondria are involved in the observed health benefits at moderate altitude. Because the experimental evidence on mitochondrial changes at moderate altitude is limited, we also evaluate dose-response associations of oxygen transport and mitochondrial functions derived from measurements at normoxia and severe hypoxia.</p><p><strong>Summary: </strong>We summarize the effects of environmental oxygen availability and changes in cellular oxygen demand/supply on mitochondrial functions and assess, how this may influence aging. Hypotheses are presented how mild hypoxia at moderate altitude (1,000-2,500 m) could improve mitochondrial function and possibly explain the reported lower levels of mortality from several age-related diseases.</p><p><strong>Key messages: </strong>It is unknown, whether continuous or intermittent types of hypoxia exposure are more effective in improving mitochondrial functions and promoting healthy aging. The combination of tissue-specific oxygen demand (e.g., during physical exercise) with mild reductions of ambient oxygen availability may enable the reported health benefits associated with moderate altitude residence.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"555-563"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144158040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GerontologyPub Date : 2025-01-01Epub Date: 2024-09-24DOI: 10.1159/000540655
Kira Scheerman, Julio R Klaverweide, Carel G M Meskers, Andrea B Maier
{"title":"Toward Senior-Friendly Hospitals: An Overview of Programs, Their Elements and Effectiveness in Improving Care.","authors":"Kira Scheerman, Julio R Klaverweide, Carel G M Meskers, Andrea B Maier","doi":"10.1159/000540655","DOIUrl":"10.1159/000540655","url":null,"abstract":"<p><strong>Background: </strong>Comprehensive \"senior-friendly hospital\" (SFH)-programs have been developed to counteract negative health outcomes in hospitalized older adults. The aim of this narrative review was to provide an overview of published SFH-programs and their elements and to summarize evidence of their effect on quality of care and patient satisfaction.</p><p><strong>Summary: </strong>A search of the databases Pubmed/Medline from inception to July 2023 and of governmental, regional, and hospital websites was performed. Programs were earmarked as SFH-programs if they primarily focused on the hospital setting, and comprised a hospital wide, multilevel approach and consisted of multiple elements. Articles and reports were included if participants were hospitalized and aged 60 years and older, and described the effect on quality of care or patient satisfaction. Articles focusing on specific patient groups or wards or on a health system or network were excluded. Ten SFH-programs were identified, with mutual elements like \"organizational support,\" \"social climate and services,\" \"processes of care,\" and \"physical environment.\" Only for the \"Acute Care for Elders\" program (USA), evidence was found showing positive effects on functional abilities, falls, delirium, length of stay, and patient satisfaction; effectiveness of other SFH-programs could not be found.</p><p><strong>Key message: </strong>Elements of SFH-programs may improve care for hospitalized older adults, but the evidence of their effectiveness is scarce.</p><p><strong>Background: </strong>Comprehensive \"senior-friendly hospital\" (SFH)-programs have been developed to counteract negative health outcomes in hospitalized older adults. The aim of this narrative review was to provide an overview of published SFH-programs and their elements and to summarize evidence of their effect on quality of care and patient satisfaction.</p><p><strong>Summary: </strong>A search of the databases Pubmed/Medline from inception to July 2023 and of governmental, regional, and hospital websites was performed. Programs were earmarked as SFH-programs if they primarily focused on the hospital setting, and comprised a hospital wide, multilevel approach and consisted of multiple elements. Articles and reports were included if participants were hospitalized and aged 60 years and older, and described the effect on quality of care or patient satisfaction. Articles focusing on specific patient groups or wards or on a health system or network were excluded. Ten SFH-programs were identified, with mutual elements like \"organizational support,\" \"social climate and services,\" \"processes of care,\" and \"physical environment.\" Only for the \"Acute Care for Elders\" program (USA), evidence was found showing positive effects on functional abilities, falls, delirium, length of stay, and patient satisfaction; effectiveness of other SFH-programs could not be found.</p><p><strong>Key message: </strong>Elements of SFH-programs ma","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-12"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11777139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GerontologyPub Date : 2025-01-01Epub Date: 2025-03-24DOI: 10.1159/000545328
Hye Jun Lee, Jung-Ha Kim
{"title":"Effect of Physical Activity Type on Serum Remnant Cholesterol Level in Korean Adults: A Nationwide Population-Based Study.","authors":"Hye Jun Lee, Jung-Ha Kim","doi":"10.1159/000545328","DOIUrl":"10.1159/000545328","url":null,"abstract":"<p><strong>Introduction: </strong>Remnant cholesterol (RC) is an important contributor to cardiovascular disease development. We aimed to investigate the effect of physical activity (PA) type on serum RC levels in Korean adults.</p><p><strong>Methods: </strong>We used data from the 2016-2021 Korea National Health and Nutrition Examination Survey, and included 32,877 adults. Serum RC was calculated by subtracting the low-density lipoprotein cholesterol and high-density lipoprotein cholesterol levels from the total cholesterol level. Hyper-remnant cholesterolemia was defined as a serum RC level of ≥30 mg/dL. PA was classified into aerobic, resistance, and walking exercises, which involved practicing 150 min of moderate, 75 min of high-intensity PA, or a combination of the 2, per week; doing resistance exercise more than 2 days per week; walking more than 150 min per week, respectively. Multivariate logistic regression analysis was performed to examine the association between serum RC and PA type.</p><p><strong>Results: </strong>Among those aged <65 years, the odds ratio (OR) of hyper-remnant cholesterolemia was 1.23 times higher in the group that did not perform resistance exercise than in the group that performed more than 2 resistance exercises per week (95% confidence interval [CI] 1.12-1.36, p < 0.0001). Among those aged ≥65 years, the OR of hyper-remnant cholesterolemia was 1.31 times higher in the group that did not practice walking exercise than in the group that walked for more than 150 min per week (95% CI: 1.11-1.55, p < 0.01).</p><p><strong>Conclusion: </strong>This study revealed that resistance exercise in those aged <65 years and walking exercise in those aged ≥65 years were significantly associated with low RC levels in Korean adults.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":"71 5","pages":"365-375"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12060825/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GerontologyPub Date : 2025-01-01Epub Date: 2025-02-07DOI: 10.1159/000543970
Shruti Karnik, Anu Gaikwad, Harishchandra Chaudhari, Priyanka Khopkar-Kale
{"title":"Identification of Potential Blood-Based Biomarkers for Frailty by Using an Integrative Approach.","authors":"Shruti Karnik, Anu Gaikwad, Harishchandra Chaudhari, Priyanka Khopkar-Kale","doi":"10.1159/000543970","DOIUrl":"https://doi.org/10.1159/000543970","url":null,"abstract":"","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":"71 4","pages":"319-320"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GerontologyPub Date : 2025-01-01Epub Date: 2025-03-12DOI: 10.1159/000545228
Martin Burtscher, Barbara Strasser, Jeannette Klimont, Barbara Leitner, Hanno Ulmer, Martin Kopp, Johannes Burtscher
{"title":"The Impact of Living at Moderate Altitude on Healthy Aging in Austria: Epidemiological Findings and Potential Underlying Mechanisms.","authors":"Martin Burtscher, Barbara Strasser, Jeannette Klimont, Barbara Leitner, Hanno Ulmer, Martin Kopp, Johannes Burtscher","doi":"10.1159/000545228","DOIUrl":"https://doi.org/10.1159/000545228","url":null,"abstract":"<p><strong>Background: </strong>Epidemiological data of populations living at moderate altitudes between 1,000 and 2,000 m suggest healthier aging when compared to people living in lower regions. Besides social determinants of health, lifestyle and cardiovascular risk factors, environmental conditions such as ambient temperature, air pollution and aeroallergens, solar radiation and in particular hypobaric hypoxia may modify the risk of disease development and mortality. The present study was aimed at (1) evaluating altitude-dependent overall and age-specific mortality rates of the most prevalent diseases using mortality registries and (2) link them to differences in lifestyle and risk factors from a population-based survey in Austria. We analyzed altitude-dependent mortality data of the entire Austrian population over a 10-year period (2013-2022, including the COVID-19 pandemic) and the distribution of cardiovascular risk factors such as hypertension, hypercholesterolemia and diabetes, lifestyle factors such as the amount of regular physical activity and dietary habits based on a representative Austrian-wide survey from 2019.</p><p><strong>Summary: </strong>Mortality was reduced in both sexes when living between 1,000 and 2,000 m compared to those living lower: by 15% (13-18%) in men and by 22% (20-24%) in women (p < 0.05). People aged between 50 and 89 years, particularly benefited from living at higher altitudes. Women lived a healthier lifestyle than men, especially at an age of above 50 years, only women older than 74 benefited from a higher located residence regarding COVID-19 mortality.</p><p><strong>Key messages: </strong>The present study confirms mortality benefits at moderate altitudes. We propose that besides lifestyle and other environmental conditions, episodically occurring hypoxic periods and related hypoxia conditioning effects represent major underlying mechanisms.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":"71 5","pages":"351-364"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of Timing of Physical Activity with Physical Frailty Incidence in Older Adults.","authors":"Masanori Morikawa, Kenji Harada, Satoshi Kurita, Chiharu Nishijima, Kazuya Fujii, Daisuke Kakita, Yukari Yamashiro, Naoto Takayanagi, Motoki Sudo, Hiroyuki Shimada","doi":"10.1159/000543283","DOIUrl":"10.1159/000543283","url":null,"abstract":"<p><strong>Introduction: </strong>Maximizing the benefits of physical activity (PA) is important to prevent physical frailty for a measure of this public health issue. This study aimed to investigate the association of timing of PA with the conversion to physical frailty.</p><p><strong>Methods: </strong>This longitudinal observational study enrolled a total of 1,310 community-dwelling Japanese older adults who enrolled in the National Center for Geriatric and Gerontology-Study of Geriatric Syndromes remained as the examined population. A health checkup was conducted to measure baseline characteristics. Subsequently, objectively measured PA was recorded for ≥7 days (≥10 h per day) for 30 days. Daily steps and the morning (6:00-12:00), afternoon (12:00-18:00), and evening (18:00-24:00) steps were calculated. A 2-year follow-up survey was administered to determine the frailty conversion, defined by newly acquired Kihon Checklist scores of 7 or higher. A logistic regression model was constructed with timing of PA and covariates as explanatory variables and frailty conversion as the dependent variable.</p><p><strong>Results: </strong>The number of conversions to frailty was 121 (9.2%). A significant association were observed between evening steps and frailty conversion (log(OR) = -0.44; 95% confidence interval [CI] = -0.87 to 0.03; p = 0.037). No significant associations were observed in the PA of morning (log(OR) = -0.03; 95% CI = -0.51 to 0.55; p = 0.906) and afternoon (log(OR) = -0.36; 95% CI = -0.78 to 0.13; p = 0.117).</p><p><strong>Conclusions: </strong>Evening PA could be advantageous in preventing frailty conversion among community-dwelling older adults. Maximizing the impact of PA may be effective against this public health concern, physical frailty.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":"71 3","pages":"165-172"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GerontologyPub Date : 2025-01-01Epub Date: 2025-03-28DOI: 10.1159/000543804
Yan Shen, Fei Sun, Yali Feng, Peter A Lichtenberg, Hongdao Meng
{"title":"Prevalence of Elder Abuse and Neglect of Persons with Dementia in Community Settings: A Systematic Review and Meta-Analysis.","authors":"Yan Shen, Fei Sun, Yali Feng, Peter A Lichtenberg, Hongdao Meng","doi":"10.1159/000543804","DOIUrl":"10.1159/000543804","url":null,"abstract":"<p><strong>Introduction: </strong>Individuals with dementia are at an elevated risk for abuse and neglect. This study aimed to estimate pooled prevalence rates of elder abuse among community-dwelling individuals with dementia using a meta-analytic approach. Additionally, it explored the heterogeneity associated with prevalence estimates through subgroup analyses.</p><p><strong>Methods: </strong>In line with the Cochrane guidelines, searches were conducted across eight academic online databases, reference lists of eligible studies, and existing systematic reviews. Eligible studies are studies published between January 1990 and March 2023 that report elder abuse among people with dementia (PWD) in community settings. The final review included 30 eligible studies from eight countries, encompassing a sample of 6,789 dependent/carer dyads.</p><p><strong>Results: </strong>The pooled rate of overall abuse among older adults with dementia is 42.6% (95% CI: 0.34-0.51). Among the various forms of abuse, psychological abuse was most prevalent, occurring in 44.8% of cases (95% CI: 0.37, 0.52), followed by financial abuse (28.3%, 95% CI: 0.03, 0.53), neglect (19.8%, 95% CI: 0.09, 0.34), and physical abuse (10%, 95% CI: 0.07, 0.13).</p><p><strong>Conclusion: </strong>The high prevalence of elder abuse highlights the significant vulnerability of individuals with dementia. The highest rate of psychological abuse indicates a particular need to address emotional trauma of PWD, as well as to adopt measures to reduce abusive or neglectful behaviors via caregiver education and support.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":"71 5","pages":"400-416"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}