Gerontology最新文献

{"title":"Sarcopenia and osteoporosis.","authors":"Edoardo Mocini, Claudia Piciocchi, Giuseppe Defeudis, Silvia Migliaccio","doi":"10.1159/000546501","DOIUrl":"https://doi.org/10.1159/000546501","url":null,"abstract":"<p><p>Sarcopenia and osteoporosis are common, interconnected conditions, in aging populations that lead to increased frailty, disability and a heightened risk of falls and fractures. Sarcopenia is the progressive loss of muscle mass, strength and function, that often coexists with osteoporosis, which is characterized by reduced bone strenght for a decreased bone mineral density (BMD) and altered bone quality. Together, these conditions form a clinical syndrome known as osteosarcopenia. Both disorders share common risk factors, including chronic inflammation, oxidative stress, and hormonal changes, which accelerate the deterioration of musculoskeletal health. This chapter discusses the overlapping pathophysiology and highlights the importance of early diagnosis and integrated therapeutic strategies. Nutritional approaches, such as ensuring adequate protein, vitamin D, and calcium intake, combined with resistance training, are essential to preserving muscle and bone health. Pharmacological treatments, including bisphosphonates for osteoporosis and emerging therapies like selective androgen receptor modulators (SARMs) and myostatin inhibitors for sarcopenia, offer promising avenues for comprehensive management. A multifaceted approach targeting both conditions can reduce the risk of falls and fractures, ultimately improving quality of life in older adults.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-13"},"PeriodicalIF":3.1,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144368781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of virtual reality training on muscle strength of the elderly: A systematic review and meta-analysis.","authors":"Hamed Zarei, Ali Asghar Norasteh, Mohamad Mottaghitalab, Michael W Ertel, Ali Brian","doi":"10.1159/000546922","DOIUrl":"https://doi.org/10.1159/000546922","url":null,"abstract":"<p><strong>Introduction: </strong>The purpose of this systematic review is to examine the effects of virtual reality training (VRT) on the muscle strength of the elderly.</p><p><strong>Methods: </strong>Primary sources were obtained from 4 databases including PubMed, SCOPUS, CENTRAL, and Web of Science. The search period covered years from inception to February 1th, 2025. Standardized mean differences (SMDs), weighted mean differences, and 95% CIs were calculated using random or fixed-effect models for outcomes.</p><p><strong>Results: </strong>Following the screening process, 38 studies involving a total of 1280 participants were included in the systematic review. The results of the meta-analysis showed that VRT increased upper-body muscle strength (1.89 [95% CI: 0.65-3.13], p=0.003), lower-body muscle strength (0.68 [95% CI: 0.46-0.91], p=0.001) and handgrip (0.45 [95% CI: 0.26-0.63], p=0.001). Additionally, the results of the meta-analysis demonstrated that there was no significant difference between VRT and traditional training (TT) on lower-body muscle strength (0.04 [95% CI: -0.26-0.36), p=0.75) and handgrip (0.06 [95% CI: -0.11-0.24], p=0.48).</p><p><strong>Conclusion: </strong>The results meta-analysis demonstrated that VRT has a positive effect on the muscle strength of all three parts of the lower limb, upper limb, and HG. Also, comparing VRT with TT, no significant difference was observed between these two types of training.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-30"},"PeriodicalIF":3.1,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144368782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Cross-Sectional Study on the Endorsement of Reporting Guidelines by Journals in Geriatrics and Gerontology.","authors":"Logan Corwin, Jacob Duncan, Shaelyn Ward, Caleb Smith, Danya Brewer, Griffin Hughes, Matt Vassar","doi":"10.1159/000546516","DOIUrl":"https://doi.org/10.1159/000546516","url":null,"abstract":"<p><strong>Introduction: </strong>The use of reporting guidelines and clinical trial registration policies by academic journals reduces bias and improves transparency in clinical research. It is unknown whether geriatric and gerontology journals mention, recommend, or require their use for the studies they may potentially publish. The purpose of this study is to assess the submission guidelines of the top geriatric and gerontology journals for their editorial recommendation or requirement of predetermined reporting guidelines and clinical trial registration.</p><p><strong>Methods: </strong>Using the 2021 Scopus CiteScore tool, we identified the top 100 journals in the \"Geriatrics and Gerontology\" subcategory. We reviewed each journal's \"Instructions to Authors\" for references to reporting guidelines commonly used for various study designs, categorizing them as \"Not Mentioned,\" \"Recommended,\" \"Does Not Require,\" or \"Required.\" Additionally, we assessed how each journal addressed clinical trial registration using the same classification system.</p><p><strong>Results: </strong>Among the 100 journals reviewed, none referenced the QUOROM statement. In contrast, the CONSORT statement was the most frequently mentioned, with 44 journals (44%) recommending or requiring its use. PRISMA guidelines were omitted by 57 journals (57%), while study registration was recommended or required by 92 journals (92%).</p><p><strong>Conclusion: </strong>The recommendation or requirement of reporting guidelines and clinical trial registration in the top 100 geriatric and gerontology journals is inconsistent. Journal editors should strongly recommend that authors follow reporting guidelines to reduce potential bias and improve transparency in the articles they publish.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-17"},"PeriodicalIF":3.1,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144368780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining Different Motor Learning Paradigms for Improving Balance Recovery Abilities Among Older Adults Random versus Block training: A Randomized Controlled Pilot Trial.","authors":"Hadas Nachmani, Inbal Paran, Moti Salti, Ilan Shelef, Noam Margalit, Michael Schwenk, Itshak Melzer","doi":"10.1159/000546907","DOIUrl":"https://doi.org/10.1159/000546907","url":null,"abstract":"<p><strong>Introduction: </strong>Older adults can reduce the risk of falls after participation in a Perturbation-Based Balance Training (PBBT). We aimed to compare two perturbation motor learning paradigms: random vs block practice.</p><p><strong>Methods: </strong>Twenty community-dwelling older adults were recruited and randomly allocated to a random PBBT group (n=8), participants were exposed to unannounced perturbations in multiple directions during each training session, or a block PBBT group (n=12) participants experienced perturbations from a single during every training session during treadmill walking. Both groups received eight training sessions over a four-weeks period that included a concurrent cognitive task during training. Primary outcome measures were parameters of reactive stepping i.e., step-thresholds in walking and kinematics of reactive stepping during walking; and secondary outcome measures were proactive balance, i.e. voluntary step test and cognitive performance. All outcomes were measured before and after PBBT.</p><p><strong>Results: </strong>Both PBBT groups improved their ability to cope with higher perturbations post training and a reduction in Center of Mass path displacement during the recovery after the perturbation in walking. No improvement was found in voluntary stepping post training, both groups, however, showed improvement in cognitive performance post-training.</p><p><strong>Discussion: </strong>Results show some improvements in reactive stepping performance but not in proactive voluntary stepping in both random and block PBBT methods, with no superiority of one training method over the other. Some improvements in cognitive performance in both groups suggest a transfer effect post training, regardless of training method. Given the small sample size, results are preliminary and should be interpreted with caution.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-23"},"PeriodicalIF":3.1,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Living in a Mountain Environment on Health and Mortality: Insights from the Alpine Population in Northern Italy.","authors":"Essi Hantikainen, Nikola Dordevic, Daniel Neunhaeuserer, Peter P Pramstaller, Johannes Rainer, Hannes Gatterer","doi":"10.1159/000546975","DOIUrl":"https://doi.org/10.1159/000546975","url":null,"abstract":"<p><strong>Introduction: </strong>Residing at moderate altitudes has been associated with various health benefits also affecting mortality risk. This study investigates life expectancy and disease-specific mortality rates among populations in the Italian Alps and in northern Italian lowland regions. Additionally, cardiometabolic health and serum metabolite concentrations of residents in an Alpine province across three distinct elevation zones (<1,000 m, 1,000-1,500 m, and >1,500 m above sea level) are studied.</p><p><strong>Methods: </strong>Data on life expectancy and mortality rate (per ten thousand) were retrieved from the ISTAT database for 6 provinces located in the Italian Alps and 6 provinces at sea level near the Alps. Using cross-sectional data from a sub-sample of the Cooperative Health Research in South Tyrol (CHRIS) study (n=6,292), we fitted multivariable adjusted logistic regression models to investigate associations between altitude and cardiometabolic health, determined by the Cumulative Illness Rating Scale. Moreover, associations between altitude and 175 serum metabolites were evaluated through linear regression models (n=1,447).</p><p><strong>Results: </strong>Population size and sex distribution were similar between provinces (p>0.485). Life expectancy at 65 years differed between areas (20.8±0.4 vs 20.1±0.3, for Alps vs sea-level, respectively, p=0.026). Mortality rate for diseases of the circulatory system was lower in the Alps than at sea-level (35.3±5.7 vs. 44.5±6.8, respectively, p=0.026). No statistically significant differences were found for mortality (Alps vs. sea-level) from all causes (108.1±15.7 vs. 126.1±15.5, p=0.065), cerebrovascular diseases (8.4±2.5 vs. 12.6±3.1, p=0.065), endocrine, nutritional and metabolic diseases (3.6±1.0 vs. 5.0±1.0, p=0.065), neoplasms (31.1±4.7 vs. 34.3±2.4 p=0.394) and diseases of the respiratory system (8.3±1.7 vs. 8.8±1.7, p=0.589). In the CHRIS study sample, living at moderate vs. low altitude level was associated with lower odds of mild to severe conditions in the hypertension (OR:0.77; 95%CI: 0.62-0.96) and endocrine-metabolic domain (OR:0.77, 95%CI: 0.61-0.97). No differences in blood serum metabolic profiles were observed between people living at different altitude levels.</p><p><strong>Conclusions: </strong>Living in the Italian Alps seems to have a positive effect on life expectancy and mortality from certain diseases compared to living at sea level in northern Italy. Furthermore, living at moderate altitude conferred some cardiometabolic health benefits in the CHRIS study population, even after corrections for confounding factors. The metabolite profile in a sub-sample did, however, not reveal any significant differences between altitude levels.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-22"},"PeriodicalIF":3.1,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between living at moderate altitude and the loss of autonomy and independence in elderlies: a French longitudinal study.","authors":"Abdallah Ghaith, Mathieu Marillier, Mallory Cals, Patrice Flore, Sébastien Bailly, Samuel Verges","doi":"10.1159/000546945","DOIUrl":"https://doi.org/10.1159/000546945","url":null,"abstract":"<p><strong>Introduction: </strong>A loss of autonomy and independence are clearly identified for the majority of aging people, with a significant impact at the individual and society levels. Permanent residency at moderate altitude appears to be associated with beneficial health effects. This study aimed at determining changes in dependency and autonomy in elderlies depending on their altitude of residence in a French Alps area.</p><p><strong>Methods: </strong>We retrospectively analyzed longitudinal data from 9 863 elderlies initially residing at home, at <500m, 500-900m or >900m above sea level, and presenting with a mild reduction in autonomy and independence. Over a 5-year period, changes in GIR score (an index of autonomy and independence ranging from 6 to 1, the lower the score the more severe the loss of autonomy and independence) annually collected in elderlies by the local authority, and potential transfer to an institution, were analyzed.</p><p><strong>Results: </strong>After 5 years of follow-up, elderlies living at higher altitude showed a significantly larger GIR score reduction (p = 0.04). The time required to lose one GIR level tended to be shorter in elderlies living at moderate altitude. Elderlies residing at moderate altitude were institutionalized significantly later that those living at lower altitude (p < 0.01).</p><p><strong>Conclusion: </strong>These results do not support a positive effect of residing at moderate altitude on elderly autonomy and independence, the latter being likely influenced by a combination of environmental, behavioral and social factors.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-17"},"PeriodicalIF":3.1,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Mood Induction and Depression on Mind Wandering Tendencies in Older and Younger Adults.","authors":"Matthew Shake, Andrea Anderson","doi":"10.1159/000546773","DOIUrl":"https://doi.org/10.1159/000546773","url":null,"abstract":"<p><strong>Introduction: </strong>Mind wandering is a pervasive experience in which attention is focused on self-generated thoughts rather than an ongoing task. Prior research found that mind wandering decreases with age, but the reasons are unclear. The present study investigated the influence of mood induction on this phenomenon.</p><p><strong>Methods: </strong>We compared older and younger adults' mind wandering tendencies during a choice reaction time (CRT) task, after exposing them to one of three mood induction conditions (positive, negative, neutral). We measured participants' reaction times and accuracy during the CRT, as well as depression levels.</p><p><strong>Results: </strong>We found that older adults reported less mind wandering, and younger adults reported specifically more future-oriented mind wandering. Additionally, while both positive and negative mood inductions significantly shifted all participants' moods, we did not replicate a prior study of younger adults that found negative mood induction increased mind wandering. Mood induction also did not alter reaction times or accuracy on the CRT.</p><p><strong>Conclusion: </strong>These findings show an age-related reduction in mind wandering, but indicate that the causes of that reduction need further investigation. The results also suggest that prior mood induction studies warrant further careful replication attempts, and that the role of emotion in age differences in mind wandering needs further emphasis.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-19"},"PeriodicalIF":3.1,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144283590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of different resistance training modalities on muscle strength in community-dwelling older adults: a network meta-analysis.","authors":"Tim Wiedenmann, Steffen Held, Tobias Morat, Ludwig Rappelt, Eduard Isenmann, Elena Berndsen, Nils-Holger Hopp, Lars Donath","doi":"10.1159/000546346","DOIUrl":"https://doi.org/10.1159/000546346","url":null,"abstract":"<p><strong>Introduction: </strong>Resistance training is widely recognized as a valuable method to enhance physical function, reduce the risk of falls, and improve overall health, independence and well-being in older adults. The training can be performed through various modalities of which the comparative effects have not yet been thoroughly elucidated. This network meta-analysis (NMA) therefore aims to compare and rank different resistance training modalities regarding their effects on strength outcomes in older adults.</p><p><strong>Methods: </strong>The studies included in this NMA were identified through a comprehensive search across three health-related and biomedical databases (PubMed, Web of Science and SPORTDiscus). We included (randomised) controlled trials that assessed the effect of resistance training modes (including: free weight training, machine-based training, body weight training, elastic band training and mixed training) in comparison to each other or to a control condition, focusing on traditional maximal strength outcomes in older individuals.</p><p><strong>Results: </strong>This NMA includes 102 trials involving 4754 community-dwelling seniors with a mean age of 70 ± 4 years (range 63 to 87 years of age). All of the included resistance training modalities yield moderate to large positive effects on strength when compared to a \"no intervention\" control condition. Machine-based training (SMD = 1.34 [95%-CI: 1.16; 1.52]) elicits the largest effects, followed by free weight (SMD = 1.15 [95%-CI: 0.28; 2.03]), elastic band (SMD = 0.93 [95%-CI: 0.49; 1.37]), mixed (SMD = 0.88 [95%-CI: 0.51; 1.25]), and bodyweight training (SMD = 0.71 [95%-CI: 0.16; 1.26]).</p><p><strong>Conclusion: </strong>Machine-based training elicits the largest effects with the smallest variance. However, our findings demonstrate that various resistance-training modalities can have large positive effects on strength development in older adults. We suggest that, with adequately chosen load criteria such as training intensity, volume and duration of the training period, the selection of the appropriate resistance training type might depend on individual preference, enjoyability and practicability.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-24"},"PeriodicalIF":3.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The potential role of mitochondria in age-related health benefits conferred by moderate hypoxia.","authors":"Johannes Burtscher, Kamilla Woznica Miskowiak, Katharina Hüfner, Hannelore Ehrenreich, Martin Kopp","doi":"10.1159/000546478","DOIUrl":"https://doi.org/10.1159/000546478","url":null,"abstract":"<p><p>Background Mitochondrial integrity and efficiency deteriorate with age and are linked to cellular senescence. Mitochondria are highly responsive to reduced oxygen availability (hypoxia), which for example occurs when exposed to altitude. We hypothesize that mitochondria are involved in the observed health benefits at moderate altitude. Because the experimental evidence on mitochondrial changes at moderate altitude is limited, we also evaluate dose-response associations of oxygen transport and mitochondrial functions derived from measurements at normoxia and severe hypoxia. Summary We summarize the effects of environmental oxygen availability and changes in cellular oxygen demand/supply on mitochondrial functions and assess, how this may influence aging. Hypotheses are presented how mild hypoxia at moderate altitude (1000 - 2500 m) could improve mitochondrial function and possibly explain the reported lower levels of mortality from several age-related diseases. Key messages It is unknown, whether continuous or intermittent types of hypoxia exposure are more effective in improving mitochondrial functions and promoting healthy aging. The combination of tissue-specific oxygen demand (for example during physical exercise) with mild reductions of ambient oxygen availability may enable the reported health benefits associated with moderate altitude residence.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-14"},"PeriodicalIF":3.1,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144158040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological effects of mountainous environments over the life span and potential implications for healthy ageing: A narrative review.","authors":"Benedikt Hösl, Martin Niedermeier, Johannes Burtscher, Martin Kopp","doi":"10.1159/000546367","DOIUrl":"https://doi.org/10.1159/000546367","url":null,"abstract":"<p><strong>Background: </strong>Healthy ageing is defined as a process of preserving functional capacity to enable well-being in old age. This concept includes both a physical and a psychological component, which can be positively influenced by spending time in nature and being physically active. Mountainous areas offer diverse opportunities to be physically active in a natural environment. However, little research is available on the psychological effects of mountain environments and mountain sports, particularly in relation to healthy ageing.</p><p><strong>Summary: </strong>We analyze the extent to which the interactions of physical activity, nature exposure, and specific characteristics of mountainous regions including hypoxia may influence mental health, based on current research, and discuss the relevance of these factors individually and in combination for healthy ageing.</p><p><strong>Key messages: </strong>In general, the benefits reported from spending time in nature or physical activity seem to be transferable to mountainous regions and/or mountain sports. The available research primarily points to positive acute and longer-term psychological (and sometimes therapeutic) effects of exposure to mountainous regions and mountain sports performed in moderate altitude on various mental health parameters, such as well-being, anxiety, and depression, which could in turn promote healthy ageing. In contrast, staying at very high or extremely high altitudes seems to be associated with negative effects on mental health. Overall, further research is needed to draw more reliable conclusions.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-17"},"PeriodicalIF":3.1,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}