Gerontology最新文献

{"title":"Association between Serum Albumin-to-Creatinine Ratio and Readmission in Elderly Heart Failure Patients: A Retrospective Cohort Study.","authors":"Leilei Guo, Li Liu, Tianwen Li, Lina Cai, Li Hu, Yueshan Zhou","doi":"10.1159/000542616","DOIUrl":"10.1159/000542616","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to investigate the relationship between the serum albumin-to-serum creatinine ratio (sACR) and readmission in elderly heart failure patients.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study using data from the PhysioNet Restricted Health Data database. The exposure variable was sACR and the outcome variable readmission. Multivariate logistic regression and subgroup analyses were performed to assess the independent association between sACR and readmission. Smooth curve fits were applied to examine the nonlinear relationship. We employed multiple imputation and E-value sensitivity analyses to assess the robustness of our results.</p><p><strong>Results: </strong>Our study included 1,725 participants, of whom 40.6% were male, 59.2% were aged 60-79 years, and 40.8% were aged 80 years and older. After adjusting for potential confounders, we found that for each unit increase in sACR, the 28-day readmission rate decreased by 48% (odds ratio [OR] = 0.52, 95% CI: 0.29-0.95, p = 0.003). The 28-day readmission rate was significantly higher in the low sACR group (sACR <0.32) than in the high sACR group (sACR >0.51) (OR = 0.47, 95% CI: 0.3-0.76, p = 0.002). Similar results were observed for 3-month and 9-month readmission. Subgroup analysis showed no significant interactions. A nonlinear relationship was observed between the sACR and readmission. Sensitivity analyses have confirmed the robustness of our results.</p><p><strong>Conclusion: </strong>There is a negative association between sACR and readmission in Chinese heart failure patients. Our study may offer novel insights into the management of heart failure readmissions.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"28-38"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Foot and Footwear Considerations for Older People: A Special Article Collection for Gerontology.","authors":"Hylton B Menz, Yvonne M Golightly","doi":"10.1159/000542899","DOIUrl":"10.1159/000542899","url":null,"abstract":"","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"47-48"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aging Alters the Sense of Force but Not the Sense of Position in the Wrist and Ankle Joints.","authors":"Mélanie Henry, Stéphane Baudry","doi":"10.1159/000542869","DOIUrl":"https://doi.org/10.1159/000542869","url":null,"abstract":"<p><strong>Introduction: </strong>The impact of aging on proprioceptive senses remains an open question. As the senses of position and force may rely on different neural substrates, we investigated the effect of aging on both senses to provide original and more comprehensive data on age-related changes in proprioception.</p><p><strong>Methods: </strong>The senses of position and force were assessed in several conditions using position- and force-reproduction tasks in young (20-40 years) and older (60-90 years) adults in the wrist (experiment 1, n = 41, 20 older adults) and ankle joints (experiment 2, n = 46, 24 older adults).</p><p><strong>Results: </strong>In both experiments, older adults exhibited larger force-reproduction errors than young adults at low (5% maximal force, p < 0.001) but not moderate forces (20% maximal force, p > 0.056). No age-related decline was observed for position-reproduction errors (p > 0.30), regardless of movement amplitude. Rare weak-to-moderate correlations were observed between position- and force-reproduction errors (r ≤ 0.53, p ≥ 0.009).</p><p><strong>Conclusion: </strong>In wrist and ankle joints, the age-related decline in proprioception is limited to the sense of force, especially for low forces. This nonuniform decline in proprioception across proprioceptive senses and testing conditions could reflect a decline in the central processing of proprioceptive information.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":"71 2","pages":"100-111"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.1159/000543486","DOIUrl":"10.1159/000543486","url":null,"abstract":"","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"252"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Views of Aging and Subjective Cognition in Middle-Aged and Older Adults: A Systematic Review.","authors":"Nikki L Hill, Justin Do, Emily Bratlee-Whitaker, Jennifer Renee Turner, Andrea Sillner, Casey Fishman, Jacqueline Mogle","doi":"10.1159/000542507","DOIUrl":"10.1159/000542507","url":null,"abstract":"<p><strong>Introduction: </strong>Views of aging have been linked with many important outcomes in older adults. Subjective cognition, or one's perception of their cognitive functioning, may be a valuable indicator of cognitive changes as individuals age, but is known to be impacted by a variety of factors. The aim of this systematic review was to synthesize the evidence on relationships between views of aging and subjective cognition, including whether and how these relationships may differ based on age.</p><p><strong>Methods: </strong>Guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria, we conducted a comprehensive literature search in four databases: PubMed, CINAHL, PsycINFO, and ProQuest Dissertations and Theses. Critical appraisal utilized the Critical Appraisal Skills Programme (CASP) checklists. Twenty sources (including 21 studies) met inclusion and exclusion criteria, from which data were systematically extracted and results narratively synthesized.</p><p><strong>Results: </strong>Seventeen out of the 21 identified studies (81%) found a relationship between more positive views of aging and better subjective cognition; however, some studies reported mixed results based on the domain of aging views. Domains that were consistently associated with subjective cognition were subjective age, attitudes toward one's own aging, aging well, and essentialist beliefs about aging. Only three studies reported age group differences or changes in associations over time, precluding conclusions about differences across middle- and older ages.</p><p><strong>Conclusion: </strong>Most studies supported associations between views of aging and subjective cognition. More longitudinal as well as qualitative research is needed to advance understanding of factors that influence these relationships.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"49-70"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of Bone Mineral Density based on Computer Tomography Images Using Deep Learning Model.","authors":"Jujia Li, Ping Zhang, Jingxu Xu, Ranxu Zhang, Congcong Ren, Fan Yang, Qian Li, Yanhong Dong, Chencui Huang, Jian Zhao","doi":"10.1159/000542396","DOIUrl":"10.1159/000542396","url":null,"abstract":"<p><strong>Introduction: </strong>The problem of population aging is intensifying worldwide. Osteoporosis has become an important cause affecting the health status of older populations. However, the diagnosis of osteoporosis and people's understanding of it are seriously insufficient. We aim to develop a deep learning model to automatically measure bone mineral density (BMD) and improve the diagnostic rate of osteoporosis.</p><p><strong>Methods: </strong>The images of 801 subjects with 2,080 vertebral bodies who underwent chest or abdominal paired computer tomography (CT) and quantitative computer tomography (QCT) scanning was retrieved from June 2020 to January 2022. The BMD of T11-L4 vertebral bodies was measured by QCT. Developing a multistage deep learning-based model to simulate the segmentation of the vertebral body and predict BMD. The subjects were randomly divided into training dataset, validation dataset and test dataset. Analyze the fitting effect between the BMD measured by the model and the standard BMD by QCT. Accuracy, precision, recall and f1-score were used to analyze the diagnostic performance according to categorization criterion measured by QCT.</p><p><strong>Results: </strong>410 males (51.2%) and 391 females (48.8%) were included in this study. Among them, there were 154 (19.2%) males and 118 (14.7%) females aged 23-44; 182 (22.7%) males and 205 (25.6%) females aged 45-64; 74 (9.2%) males and 68 (8.5%) females aged 65-84. The number of vertebral bodies in the training dataset, the validation dataset, and the test dataset was 1433, 243, 404, respectively. In each dataset, the BMD of males and females decreases with age. There was a significant correlation between the BMD measured by the model and QCT, with the coefficient of determination (R2) 0.95-0.97. The diagnostic accuracy based on the model in the three datasets was 0.88, 0.91, and 0.91, respectively.</p><p><strong>Conclusion: </strong>The proposed multistage deep learning-based model can achieve automatic measurement of vertebral BMD and performed well in the prediction of osteoporosis.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"71-80"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behind Bars: Exploring Health and Geriatric Conditions among Incarcerated Older People in Mexican Prisons.","authors":"Natalia Sanchez Garrido, Julio Manuel Fernandez-Villa, Miguel Germán Borda, Carmen Garcia-Peña, Mario Ulises Perez Zepeda","doi":"10.1159/000542624","DOIUrl":"10.1159/000542624","url":null,"abstract":"<p><strong>Introduction: </strong>The aging process of the incarcerated population is a growing concern, yet there are few data on older adults in this demographic group. Hence, this study sought to examine the health status of older adults who are incarcerated in Mexican prisons and its association with the duration of their imprisonment.</p><p><strong>Methods: </strong>This is a secondary analysis of the 2021 Mexico National Prisons Survey. We analyzed 50-year-old and older prisoners and performed a descriptive analysis of the sample's age, sex, sociodemographic variables, and chronic conditions. Multivariate analysis stratified by age was performed to assess the effect of the time spent in prison on older prisoners' health.</p><p><strong>Results: </strong>The mean age was 56.95 (±6.4 SD), and the mean duration of imprisonment was 8.93 years (±6.94 SD). Regarding health conditions, 17.80% had diabetes, 29.62% had hypertension, 10.33% had suicidal ideation, and 40.87% were visually impaired, 17.01% had hearing impairment, and 17.64% had mobility impairment. Multivariate analysis revealed that among categories of imprisonment duration, longer time imprisoned was associated with an increased risk of diabetes and hypertension for all groups but was not associated with mobility impairment or suicidal ideation except in the younger group.</p><p><strong>Conclusion: </strong>Longer periods of incarceration appear to be associated with a greater occurrence of diabetes and hypertension in older prisoners. Sensory impairments and suicidal ideation are mainly identified in younger prisoners, while mobility impairments do not appear to be influenced by the time spent in prison. Further research needs to be done in prisons, where the addition of physical performance tests and cognitive tests could help further study geriatric conditions in older prisoners.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"39-46"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Temporal Relation of Physical Function with Cognition and the Influence of Brain Health in the Oldest-Old.","authors":"Nienke Legdeur, Maryam Badissi, Vikram Venkatraghavan, Davis C Woodworth, Fanny Orlhac, Jean-Sébastien Vidal, Frederik Barkhof, Claudia H Kawas, Pieter Jelle Visser, María M Corrada, Majon Muller, Hanneke F M Rhodius-Meester","doi":"10.1159/000542395","DOIUrl":"10.1159/000542395","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Physical function and cognition seem to be interrelated, especially in the oldest-old. However, the temporal order in which they are related and the role of brain health remain uncertain.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We included 338 participants (mean age 93.1 years) from two longitudinal cohorts: the UCI 90+ Study and EMIF-AD 90+ Study. We tested the association between physical function (Short Physical Performance Battery, gait speed, and handgrip strength) at baseline with cognitive decline (MMSE, memory tests, animal fluency, Trail Making Test (TMT-) A, and digit span backward) and the association between cognition at baseline with physical decline (mean follow-up 3.3 years). We also tested whether measures for brain health (hippocampal, white matter lesion, and gray matter volume) were related to physical function and cognition and whether brain health was a common driver of the association between physical function and cognition by adding it as confounder (if applicable).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Better performance on all physical tests at baseline was associated with less decline on MMSE, memory, and TMT-A. Conversely, fewer associations were significant, but better scores on memory, TMT-A, and digit span backward were associated with less physical decline. When adding measures for brain health as confounder, all associations stayed significant except for memory with gait speed decline.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;In the oldest-old, physical function and cognition are strongly related, independently of brain health. Also, the association between physical function and cognitive decline is more pronounced than the other way around, suggesting a potential for slowing cognitive decline by optimizing physical function.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Physical function and cognition seem to be interrelated, especially in the oldest-old. However, the temporal order in which they are related and the role of brain health remain uncertain.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We included 338 participants (mean age 93.1 years) from two longitudinal cohorts: the UCI 90+ Study and EMIF-AD 90+ Study. We tested the association between physical function (Short Physical Performance Battery, gait speed, and handgrip strength) at baseline with cognitive decline (MMSE, memory tests, animal fluency, Trail Making Test (TMT-) A, and digit span backward) and the association between cognition at baseline with physical decline (mean follow-up 3.3 years). We also tested whether measures for brain health (hippocampal, white matter lesion, and gray matter volume) were related to physical function and cognition and whether brain health was a common driver of the association between physical function and cognition by adding it as confounder (if applicable).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Better performance on all physical tests at baseline was associated with less decline on MMSE, memory, and TMT-A. Conversely, fewer a","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"13-27"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11772116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toward Senior-Friendly Hospitals: An Overview of Programs, Their Elements and Effectiveness in Improving Care.","authors":"Kira Scheerman, Julio R Klaverweide, Carel G M Meskers, Andrea B Maier","doi":"10.1159/000540655","DOIUrl":"10.1159/000540655","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Comprehensive \"senior-friendly hospital\" (SFH)-programs have been developed to counteract negative health outcomes in hospitalized older adults. The aim of this narrative review was to provide an overview of published SFH-programs and their elements and to summarize evidence of their effect on quality of care and patient satisfaction.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Summary: &lt;/strong&gt;A search of the databases Pubmed/Medline from inception to July 2023 and of governmental, regional, and hospital websites was performed. Programs were earmarked as SFH-programs if they primarily focused on the hospital setting, and comprised a hospital wide, multilevel approach and consisted of multiple elements. Articles and reports were included if participants were hospitalized and aged 60 years and older, and described the effect on quality of care or patient satisfaction. Articles focusing on specific patient groups or wards or on a health system or network were excluded. Ten SFH-programs were identified, with mutual elements like \"organizational support,\" \"social climate and services,\" \"processes of care,\" and \"physical environment.\" Only for the \"Acute Care for Elders\" program (USA), evidence was found showing positive effects on functional abilities, falls, delirium, length of stay, and patient satisfaction; effectiveness of other SFH-programs could not be found.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Key message: &lt;/strong&gt;Elements of SFH-programs may improve care for hospitalized older adults, but the evidence of their effectiveness is scarce.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Comprehensive \"senior-friendly hospital\" (SFH)-programs have been developed to counteract negative health outcomes in hospitalized older adults. The aim of this narrative review was to provide an overview of published SFH-programs and their elements and to summarize evidence of their effect on quality of care and patient satisfaction.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Summary: &lt;/strong&gt;A search of the databases Pubmed/Medline from inception to July 2023 and of governmental, regional, and hospital websites was performed. Programs were earmarked as SFH-programs if they primarily focused on the hospital setting, and comprised a hospital wide, multilevel approach and consisted of multiple elements. Articles and reports were included if participants were hospitalized and aged 60 years and older, and described the effect on quality of care or patient satisfaction. Articles focusing on specific patient groups or wards or on a health system or network were excluded. Ten SFH-programs were identified, with mutual elements like \"organizational support,\" \"social climate and services,\" \"processes of care,\" and \"physical environment.\" Only for the \"Acute Care for Elders\" program (USA), evidence was found showing positive effects on functional abilities, falls, delirium, length of stay, and patient satisfaction; effectiveness of other SFH-programs could not be found.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Key message: &lt;/strong&gt;Elements of SFH-programs ma","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-12"},"PeriodicalIF":3.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11777139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Engagement in the Community-Based Going-Out Programs and the Association with Physical Frailty Assessed by the Kihon Checklist: A Cohort Study.","authors":"Masanori Morikawa, Kenji Harada, Satoshi Kurita, Chiharu Nishijima, Kazuya Fujii, Daisuke Kakita, Yukari Yamashiro, Naoto Takayanagi, Motoki Sudo, Hiroyuki Shimada","doi":"10.1159/000542089","DOIUrl":"10.1159/000542089","url":null,"abstract":"<p><strong>Introduction: </strong>In efforts to address the public health concern of physical frailty prevention, community-based programs without supervision are anticipated, yet efficacy has not been shown. We aimed to investigate the association of engaging in an unsupervised, community-based going-out program on the incidence of physical frailty among older adults.</p><p><strong>Methods: </strong>A cohort observational study was employed. Following a baseline assessment during 2015 and 2017 in Japan, we observed 1,350 older adults engage in a community-based going-out program for 12 months. Participants were categorized into either a non-engaged or engaged group via propensity score matching. A follow-up survey (mean period = 920 ± 76 days) was conducted to investigate the occurrence of physical frailty using the Kihon Checklist. The incidence of frailty, absolute risk reduction, and number needed to treat for program engagement were calculated. The odds ratio (OR) in engaged group compared with the non-engaged group was determined in a logistic regression model.</p><p><strong>Results: </strong>Incidence of frailty was 15.1% in non-engaged group (n = 107 out of 628) and 8.3% in the engaged group (n = 53 out of 628). The number needed to treat and its 95% confidence interval were 21 (12-63) after matching. Compared with matched non-engaged group (OR 1.0), the OR and 95% confidence interval of matched engaged group for occurrence of physical frailty were 0.61 (0.42-0.87).</p><p><strong>Conclusions: </strong>Engaging in the unsupervised community-based going-out program could prevent one incidence of physical frailty in every 21 participants and may thus contribute to preventing physical frailty at the population level.</p>","PeriodicalId":12662,"journal":{"name":"Gerontology","volume":" ","pages":"1-11"},"PeriodicalIF":3.1,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142768329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}