Global Challenges最新文献_第4页

Bactericidal, Virucidal, and Biocompatible Properties of 3D Printed Materials Enhanced with Copper and Zinc Nanoparticles 铜和锌纳米颗粒增强的3D打印材料的杀菌、杀毒和生物相容性

IF 6.4 4区综合性期刊

Global Challenges Pub Date : 2025-06-16 DOI: 10.1002/gch2.202500106

Andrei-Florin Sandu, Lauren Acton, Phillip Gould

{"title":"Bactericidal, Virucidal, and Biocompatible Properties of 3D Printed Materials Enhanced with Copper and Zinc Nanoparticles","authors":"Andrei-Florin Sandu, Lauren Acton, Phillip Gould","doi":"10.1002/gch2.202500106","DOIUrl":"https://doi.org/10.1002/gch2.202500106","url":null,"abstract":"The heightened spread of pathogens due to population growth, urbanization, and climate change presents significant health challenges, exacerbated by high transmission, virulence, antimicrobial resistance (AMR), and novel variants. Hospital-acquired infections (HAI) affect 1 in 31 hospitalized patients, costing $28.4 billion annually. This study introduces a novel approach to pathogen control by integrating copper and zinc oxide nanoparticles into 3D printed Stereolithography (SLA) materials. The 3D impregnated material demonstrates reproducibility and efficacy across different 3D platforms, showcasing complete bactericidal/fungicidal effects against twelve diverse species and a 4 log virucidal activity on eight clinically relevant viral species within 2 h. No significant cytotoxicity is observed in primary human keratinocytes after 2 h of contact. The material maintains its antipathogenic activity after a year of accelerated ageing, suggesting enhances stability and performance over time. This method addresses the limitations of conventional cleaning and surface spraying, which often fall short in efficacy and longevity; for the first time, the incorporation of commercially available nanoparticles into 3D printable materials offers a versatile long-lasting antipathogenic and biocompatible solution for high-contact surfaces in public and clinical settings, reducing the need for cleaning surfaces while limiting infection rates, the threat of AMR, and other future infectious outbreaks.","PeriodicalId":12646,"journal":{"name":"Global Challenges","volume":"9 8","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gch2.202500106","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144885289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determination of Groundwater Vulnerability for Protection of the Drinking Water Basins: A Case Study From Türkiye, Kesikköprü Dam Lake Basin 饮用水流域保护地下水脆弱性的确定——以<s:1> rkiye， Kesikköprü坝湖流域为例

IF 6.4 4区综合性期刊

Global Challenges Pub Date : 2025-06-13 DOI: 10.1002/gch2.202500237

Olcay Gülçiçek Uysal, Kağan Cebe, Mert Cüylan, Olgu Yurttaş

{"title":"Determination of Groundwater Vulnerability for Protection of the Drinking Water Basins: A Case Study From Türkiye, Kesikköprü Dam Lake Basin","authors":"Olcay Gülçiçek Uysal, Kağan Cebe, Mert Cüylan, Olgu Yurttaş","doi":"10.1002/gch2.202500237","DOIUrl":"https://doi.org/10.1002/gch2.202500237","url":null,"abstract":"This study investigates the intrinsic groundwater vulnerability of the Kesikköprü Dam Lake Basin, a critical drinking water source for Ankara, Central Anatolia Türkiye. The DRASTIC model is applied within a Geographic Information Systems (GIS) framework, using seven hydrogeological parameters to generate a vulnerability map. Results indicate that most of the basin falls within “very low” and “low” vulnerability zones, with “medium” vulnerability observed in localized recharge-prone areas. Model validation is conducted using nitrate and total organic carbon concentrations, which represent pollution from agricultural and domestic wastewater sources. The spatial correlation between these indicators and DRASTIC output supports the model's reliability. Importantly, this research also integrates anthropogenic influences by evaluating the spatial distribution of agricultural, wastewater, and mining activities relative to vulnerability zones. While natural conditions suggest low contamination potential, the cumulative and long-term effects of these activities highlight significant risks in certain areas. To the best of the knowledge, this is the first study to validate a DRASTIC-based vulnerability map for the Kesikköprü Basin while addressing anthropogenic pressures. The findings offer a practical decision-making tool for land-use planning and sustainable groundwater management, both regionally and in similar hydrogeological contexts worldwide.","PeriodicalId":12646,"journal":{"name":"Global Challenges","volume":"9 8","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gch2.202500237","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144888245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to “Future Energy Breakthroughs–Implications for the Hydrocarbon Economies of the Arabian Gulf” 更正“未来能源突破-对阿拉伯海湾碳氢化合物经济的影响”

IF 4.4 4区综合性期刊

Global Challenges Pub Date : 2025-06-13 DOI: 10.1002/gch2.70011

Logan Cochrane, Dhabia Al Mohannadi, Sa'd Shannak, Yoshihide Wada, Esra Al Eisa, Mohamad Hejazi

引用次数: 0

A Ray of Hope: Gamma Radiation for Microplastic Remediation (Global Challenges 6/2025) 希望之光：伽玛辐射用于微塑料修复（全球挑战6/2025）

IF 4.4 4区综合性期刊

Global Challenges Pub Date : 2025-06-10 DOI: 10.1002/gch2.70010

Dhanalakshmi Vadivel, Claudio Casella, Adriana Laca, Mario Díaz, Daniele Dondi

引用次数: 0

Prospects and Challenges of Proton Conducting Cerates in Electrochemical Hydrogen Devices for Clean Energy Systems: A Review 质子导电铈在清洁能源系统氢电化学装置中的应用前景与挑战

IF 4.4 4区综合性期刊

Global Challenges Pub Date : 2025-06-09 DOI: 10.1002/gch2.202500119

M. Khalid Hossain, Ranjit C. Das, M. Imran Hossain, M. Atikur Rahman, Prabhu Paramasivam, Ripel Chakma, Mongi Amami, Mohamed H. H. Mahmoud, R. Bousbih, Rajesh Haldhar, Kenichi Hashizume

{"title":"Prospects and Challenges of Proton Conducting Cerates in Electrochemical Hydrogen Devices for Clean Energy Systems: A Review","authors":"M. Khalid Hossain, Ranjit C. Das, M. Imran Hossain, M. Atikur Rahman, Prabhu Paramasivam, Ripel Chakma, Mongi Amami, Mohamed H. H. Mahmoud, R. Bousbih, Rajesh Haldhar, Kenichi Hashizume","doi":"10.1002/gch2.202500119","DOIUrl":"https://doi.org/10.1002/gch2.202500119","url":null,"abstract":"The growing demand for green energy and global concern about environmental issues raise the demand for alternative, environmentally friendly energy sources. Electrochemical hydrogen devices are widely investigated as a potential solution for clean and renewable energy. Proton-conducting oxides (PCOs) used as an electrolyte are required in electrochemical devices to transport protons. Chemical stability and proton conductivity are essential properties to evaluate a suitable electrolyte for these devices. Doped cerate-based materials exhibit excellent proton conductivity and chemical stability, making them suitable as electrolyte materials for hydrogen devices. Techniques including doping, co-doping, sintering aid, and different fabrication processes enhance the proton conductivity and mechanical stability of proton-conducting materials. This paper highlights the current development of cerate-based PCOs used as an electrolyte in electrochemical devices named hydrogen pumps, hydrogen isotope separation systems, tritium recovery systems, and hydrogen sensors, which could be used in the nuclear fusion reactors, among other electrochemical hydrogen devices. The center part of this review paper summarizes the most recent research studies on these applications and offers a thorough understanding of the impact of doping, different synthesis methods, sintering aids, and operating environments on the composition, morphology, and performance of cerate electrolyte materials. The challenges and prospects of proton-conducting cerates are also discussed. This paper provides an insightful pathway for the researcher to further research in this field.","PeriodicalId":12646,"journal":{"name":"Global Challenges","volume":"9 7","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gch2.202500119","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144598629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preparation and Characterization of Carbon Quantum Dots (CQD) and CuFe2O4–CQD Composite Materials for Photo and Electrochemical Applications 碳量子点（CQD）和CuFe2O4-CQD光电复合材料的制备与表征

IF 4.4 4区综合性期刊

Global Challenges Pub Date : 2025-06-09 DOI: 10.1002/gch2.202500044

Esakkimuthu Shanmugasundaram, Amos Ravi, Nithesh Kumar Krishnan, Kannan Vellaisamy, Murali Krishnan Mani, Na'il Saleh, Stalin Thambusamy

{"title":"Preparation and Characterization of Carbon Quantum Dots (CQD) and CuFe2O4–CQD Composite Materials for Photo and Electrochemical Applications","authors":"Esakkimuthu Shanmugasundaram, Amos Ravi, Nithesh Kumar Krishnan, Kannan Vellaisamy, Murali Krishnan Mani, Na'il Saleh, Stalin Thambusamy","doi":"10.1002/gch2.202500044","DOIUrl":"https://doi.org/10.1002/gch2.202500044","url":null,"abstract":"The Carbon quantum dots (CQD) is prepared from ascorbic acid, and the photophysical, structural, and metal sensing behavior of the CQD is investigated in detail. The negatively charged CQD, along with the vibrant functional groups, can absorb the positive charge ferric ion (Fe3+) and copper(II) ion or cupric ion (Cu2+) ions with the help of electrostatic attractive forces. In this process, the aggregation of CQD around the Fe3+ and Cu2+ ions results in confirmation that CQD is a fluorescence sensor probe that forms a metal complex, CQD-Fe3+ and CQD-Cu2+. The composite structural and functional group properties are investigated by the different analytical techniques. Moreover, the copper ferrite (CuFe2O4–CQD) electrochemical performances are evaluated in three and two-electrode systems by Cyclic voltammetry (CV), Galvanostatic charge-discharge (GCD), and Electrochemical Impedance Spectroscopy (EIS) techniques. The CuFe2O4–CQD electrode's specific capacitance value is 410 F g−1 at 2 A g−1 with 100% capacitance retention after 3000 cycles. Moreover, the methylene blue dye degradation efficiency of CuFe2O4–CQD is 91% in 120 min. The CuFe2O4–CQD composite has a synergistic effect between the CQD and CuFe2O4, which delivers a higher photocatalytic effect because which reduced recombination and enhancing charge transport.","PeriodicalId":12646,"journal":{"name":"Global Challenges","volume":"9 7","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gch2.202500044","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144598624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Energy Sources and Thermal Management Technologies for Electric Vehicle Batteries: A Technical Review 电动汽车电池的能源和热管理技术：技术综述

IF 4.4 4区综合性期刊

Global Challenges Pub Date : 2025-06-02 DOI: 10.1002/gch2.202500083

Md Atiqur Rahman, Gurrala Mohith Venu Reddy, Rajeshwari Chatterjee, Soumili Hait, S. M. Mozammil Hasnain, Prabhu Paramasivam, Leliso Hobicho Dabelo

{"title":"Energy Sources and Thermal Management Technologies for Electric Vehicle Batteries: A Technical Review","authors":"Md Atiqur Rahman, Gurrala Mohith Venu Reddy, Rajeshwari Chatterjee, Soumili Hait, S. M. Mozammil Hasnain, Prabhu Paramasivam, Leliso Hobicho Dabelo","doi":"10.1002/gch2.202500083","DOIUrl":"https://doi.org/10.1002/gch2.202500083","url":null,"abstract":"Efficient thermal management of high-power lithium-ion batteries (LiBs) is critical for ensuring safety, longevity, and performance in electric vehicles (EVs). Battery thermal management systems (BTMS) play a crucial role in regulating temperature, as LiBs are highly sensitive to thermal fluctuations. Excessive heat generation during charging and discharging can degrade battery performance, reduce lifespan, and pose safety risks. Traditional cooling methods, such as air and liquid cooling, often require additional power and complex components, making them less effective for high-energy–density batteries. As a result, recent advancements focus on immersion, indirect, and hybrid cooling solutions. Among these, phase change material (PCM)-based BTMS has emerged as a promising passive cooling approach. PCMs efficiently absorb and store heat, maintaining optimal battery temperature without external power. Their thermal performance is further enhanced by integrating expanded graphite (EG) fillers, metal foams, or fins, improving heat dissipation. This review examines recent progress (2019–2024) in BTMS technologies, with a particular focus on PCM applications in fast-charging conditions. It also discusses BTMS performance under extreme environments, such as high temperatures, sub-zero conditions, and abuse scenarios. Future research directions are highlighted to optimize BTMS for next-generation EVs, ensuring improved battery safety, efficiency, and thermal stability.","PeriodicalId":12646,"journal":{"name":"Global Challenges","volume":"9 7","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gch2.202500083","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144598353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficient Oxidative Polymerization of Hydroxytyrosol Using Horseradish Peroxidase Immobilized on a Magnetic Silica-Coated Nanocatalyst 磁性二氧化硅包覆纳米催化剂上固定化辣根过氧化物酶对羟基酪醇的高效氧化聚合

IF 4.4 4区综合性期刊

Global Challenges Pub Date : 2025-05-29 DOI: 10.1002/gch2.202500064

Fatih Sevim, Gülşah Aktaş, Hakan Kiziltaş, Fatih Demir, Taner Tekin

{"title":"Efficient Oxidative Polymerization of Hydroxytyrosol Using Horseradish Peroxidase Immobilized on a Magnetic Silica-Coated Nanocatalyst","authors":"Fatih Sevim, Gülşah Aktaş, Hakan Kiziltaş, Fatih Demir, Taner Tekin","doi":"10.1002/gch2.202500064","DOIUrl":"https://doi.org/10.1002/gch2.202500064","url":null,"abstract":"Enzyme-based catalysis has gained considerable attention in recent years due to its eco-friendly and selective nature. However, the inability to recover enzymes after the reaction significantly increases operational costs. In this study, a reusable nanocatalyst Fe3O4@SiO2@APTES@GA@HRP is synthesized and applied in the oxidative polymerization of hydroxytyrosol. Fe3O4 nanoparticles are prepared using the solvothermal method, followed by silica coating via the Stöber process. Amino-functionalization is achieved with 3-aminopropyltriethoxysilane (APTES), and horseradish peroxidase (HRP) is immobilized through glutaraldehyde (GA)-mediated azomethine bonding. The synthesized catalyst is characterized using SEM, EDS, FTIR, Q-TOF, ¹H-NMR, and Zetasizer analyses, all confirming successful immobilization. Polymerization reactions are conducted in acetate buffer (pH 5, 25 °C), resulting in a 73% yield. The catalyst is reusable for up to ten cycles, and the molecular weight of the produced poly(hydroxytyrosol) is approximately 30,000 g mol−1. These findings demonstrate the promising application of recyclable enzyme nanocatalysts in green polymer chemistry.","PeriodicalId":12646,"journal":{"name":"Global Challenges","volume":"9 7","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gch2.202500064","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144598487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Transdisciplinary Framework to Bridge Science–Policy–Development Gaps in Global Land Management Initiatives 弥合全球土地管理倡议中科学-政策-发展差距的跨学科框架

IF 6.4 4区综合性期刊

Global Challenges Pub Date : 2025-05-22 DOI: 10.1002/gch2.202400261

Nigussie Haregeweyn, Atsushi Tsunekawa, Ayele Almaw Fenta, Pasquale Borrelli, Panos Panagos, Ermias Aynekulu, Takeshi Abe, Peri Pablo, Simon West

{"title":"A Transdisciplinary Framework to Bridge Science–Policy–Development Gaps in Global Land Management Initiatives","authors":"Nigussie Haregeweyn, Atsushi Tsunekawa, Ayele Almaw Fenta, Pasquale Borrelli, Panos Panagos, Ermias Aynekulu, Takeshi Abe, Peri Pablo, Simon West","doi":"10.1002/gch2.202400261","DOIUrl":"https://doi.org/10.1002/gch2.202400261","url":null,"abstract":"Effective implementation of Sustainable Land Management (SLM) remains a major challenge worldwide because of its weak integration within the domains of science, policy, and development practice. Based on global analyses of soil erosion risk and the degree of implementation of SLM research, policies, and practices at the country level, we propose a transdisciplinary framework to address soil erosion through SLM. In the analysis, we used indices of the policy–development, science–policy, and science–development interfaces to evaluate the overall science–policy–development interface (SPDI) in 236 countries. Over 190 countries (81%) were found to be currently facing moderate or high risk of increased soil erosion from two or more erosion processes, and 182 countries (77%) were found to have a SPDI level that was lower than their soil erosion risk implying the urgent need for a transdisciplinary framework that supports the implementation of future soil erosion research and development projects. Our proposed transdisciplinary framework comprises seven stages, starting from “shared research framing” and ending with “ex-post evaluation”. The framework’s practical application is discussed in the context of a recent project, emphasizing the need for country-specific studies to develop tailored frameworks.","PeriodicalId":12646,"journal":{"name":"Global Challenges","volume":"9 8","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gch2.202400261","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144888444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dry Eye Disease: Oxidative Stress on Ocular Surface and Cutting-Edge Antioxidants 干眼病：眼表氧化应激和尖端抗氧化剂

IF 4.4 4区综合性期刊

Global Challenges Pub Date : 2025-05-14 DOI: 10.1002/gch2.202500068

Rong Hu, Jian Shi, Can-Ming Xie, Xiao-Lei Yao

{"title":"Dry Eye Disease: Oxidative Stress on Ocular Surface and Cutting-Edge Antioxidants","authors":"Rong Hu, Jian Shi, Can-Ming Xie, Xiao-Lei Yao","doi":"10.1002/gch2.202500068","DOIUrl":"https://doi.org/10.1002/gch2.202500068","url":null,"abstract":"Dry eye disease (DED), a multifactorial ocular surface disorder characterized by tear film instability, is pathologically linked to oxidative damage. The accumulation of reactive oxygen species (ROS) across ocular tissues not only directly damages nucleic acids, proteins, and lipids, but also functions as an upstream driver of inflammation and tear hyperosmolarity, collectively disrupting cellular homeostasis. This review comprehensively delineates the mechanistic interplay between oxidative stress (OS) and DED pathogenesis, synthesizing evidence on enzymatic/ nonenzymatic antioxidant alterations in samples of corneal, lacrimal, conjunctival, meibomian gland, and tear tissues, alongside quantitative profiling of OS biomarkers, such as 4-hydroxynonenal (4HNE), malondialdehyde (MDA), 8-hydroxy-2′-deoxyguanosine (8-OHdG), and 3-nitrotyrosine (3-NT). Furthermore, the therapeutic mechanisms of clinically approved and investigational antioxidants, including SKQ1, rebamipide, mitoquinone, elamipretide, lactoferrin, nanozymes, graphene quantum dots, tetrahedral frame of nucleic acids, and Chinese medicine monomers are critically evaluated. With the changes in the modern social environment and lifestyle, the influence of OS on DED is gradually expanding. Antioxidant-based interventions are poised to become cornerstone components of multimodal DED management strategies.","PeriodicalId":12646,"journal":{"name":"Global Challenges","volume":"9 7","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/gch2.202500068","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144598329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0