Angewandte Chemie International Edition最新文献_第5页

Ether-Anchored MOFs Enable Stable Pseudosuspension Electrolytes for High-Energy Lithium Metal Batteries. 醚锚定mof为高能锂金属电池提供稳定的假悬浮电解质。

IF 16.6 1区化学

Angewandte Chemie International Edition Pub Date : 2025-10-21 DOI: 10.1002/anie.202518384

Yu Han,Yong Chen,Tonghui Zhang,Zhiye Hao,Lianlian He,Weiting Ma,Taolue Wen,Shunshun Zhao,Qimin Peng,Zhenzhen Shen,Robin Wang,Guoxiu Wang,Shimou Chen

{"title":"Ether-Anchored MOFs Enable Stable Pseudosuspension Electrolytes for High-Energy Lithium Metal Batteries.","authors":"Yu Han,Yong Chen,Tonghui Zhang,Zhiye Hao,Lianlian He,Weiting Ma,Taolue Wen,Shunshun Zhao,Qimin Peng,Zhenzhen Shen,Robin Wang,Guoxiu Wang,Shimou Chen","doi":"10.1002/anie.202518384","DOIUrl":"https://doi.org/10.1002/anie.202518384","url":null,"abstract":"Rational electrolyte design, capable of simultaneously accelerating bulk ion transport and stabilizing interfacial chemistry, is indispensable for achieving high-energy-density lithium metal batteries (LMBs). Here, we demonstrate that short-chain ether-functionalized metal-organic frameworks (S@MOFs) meet these requirements by efficiently tailoring Li⁺ coordination and reconstructing the electrode/electrolyte interphase, achieving durable interfacial ion transport kinetics. Synergistic experimental and theoretical investigations demonstrate that the S@MOF-based electrolyte features distinctive pseudosuspension characteristics, harnessing ether chemistry that affords Li-metal compatibility and Li-salt coordination in concert with MOF's abundant binding sites and ordered rigid frameworks. The resultant S@MOF-based electrolyte delivers robust thermodynamic stability across -10 to 60 °C, even in LiNi0.8Co0.1Mn0.1O2 (NCM811)||Li full-cell configurations. Under lean-electrolyte and 50 µm-thick Li-metal configurations, it achieves 92.40% capacity retention for LiCoO2||Li after 1000 cycles. Remarkably, 90.70% for quasi-solid-state NCM811||Li (500 cycles), and 93.21% for Na3V2(PO4)3||Na (3000 cycles) were obtained, confirming its broad applicability across alkali-metal battery chemistries.","PeriodicalId":125,"journal":{"name":"Angewandte Chemie International Edition","volume":"59 1","pages":"e202518384"},"PeriodicalIF":16.6,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145338581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Sonosensitive Heterometallic Polyoxometalate for Highly Efficient Chemo-Sonodynamic Synergistic Cancer Therapy. 一种用于高效化学-声动力协同癌症治疗的声敏感异金属多金属酸盐。

IF 16.6 1区化学

Angewandte Chemie International Edition Pub Date : 2025-10-21 DOI: 10.1002/anie.202514859

Man-Yi Du,Hui-Ping Xiao,Ruo-Fei Xu,Xian-Bin Sun,Xin-Yi Wang,Dong-Miao Li,Sheng-Nan Yue,Zi-Zhong Zhang,Xing Huang,Yu Gao,Xiu-Ling Shang,Xin-Xiong Li,Shou-Tian Zheng

{"title":"A Sonosensitive Heterometallic Polyoxometalate for Highly Efficient Chemo-Sonodynamic Synergistic Cancer Therapy.","authors":"Man-Yi Du,Hui-Ping Xiao,Ruo-Fei Xu,Xian-Bin Sun,Xin-Yi Wang,Dong-Miao Li,Sheng-Nan Yue,Zi-Zhong Zhang,Xing Huang,Yu Gao,Xiu-Ling Shang,Xin-Xiong Li,Shou-Tian Zheng","doi":"10.1002/anie.202514859","DOIUrl":"https://doi.org/10.1002/anie.202514859","url":null,"abstract":"Chemo-sonodynamic synergistic therapy (CSDT) integrates the advantages of both chemodynamic therapy (CDT) and sonodynamic therapy (SDT), including specificity, non-invasiveness, high penetration, and controllability, and it is especially suitable for deep-seated tumors. However, there is still a lack of effective CSDT agents with long-term stability, excellent water solubility, biocompatibility, and highly efficient catalytic activities. To address these challenges, we report a rare sonosensitive polyoxometalate (POM), H11[Er2Sb2W7O23(OH)(DMF)2(SbW9O33)2]·17H2O (ErSbW), featuring an atomically precise capsule-like structure with good solubility, molecular stability, and biosafety under physiological conditions. In vitro studies reveal ErSbW's remarkable CDT efficiency in catalyzing the generation of reactive oxygen species (ROS). More importantly, the efficiency can be further distinctly augmented by three times with the presence of ultrasound irradiation, suggesting a pronounced synergistic enhancement effect in ErSbW. Most notably, ErSbW-mediated CSDT achieved complete eradication of deep-seated tumors in a melanoma model at the dose of 35 µg kg-1. This work not only provides a unique POM-based molecular agent for CSDT but also demonstrates the great potential of POM materials in synergistic cancer therapies.","PeriodicalId":125,"journal":{"name":"Angewandte Chemie International Edition","volume":"12 1","pages":"e202514859"},"PeriodicalIF":16.6,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145331883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular Design-Driven Interface Engineering Enabling Simultaneous Defect Passivation and Enhanced Hole Extraction in Perovskite Solar Cells. 分子设计驱动的界面工程实现钙钛矿太阳能电池缺陷钝化和增强孔提取。

IF 16.6 1区化学

Angewandte Chemie International Edition Pub Date : 2025-10-21 DOI: 10.1002/anie.202513869

Wei Jia,Riming Sun,Jingyuan Qiao,Guangchao Shi,Qiangqiang Zhao,Ziyan Gong,Siming Zheng,Ruida Xu,Jingzhi Shang,Lin Song,Kai Wang,Wei Huang,Ruihao Chen,Yiyun Fang,Hongqiang Wang,Zi-Qiang Rong

{"title":"Molecular Design-Driven Interface Engineering Enabling Simultaneous Defect Passivation and Enhanced Hole Extraction in Perovskite Solar Cells.","authors":"Wei Jia,Riming Sun,Jingyuan Qiao,Guangchao Shi,Qiangqiang Zhao,Ziyan Gong,Siming Zheng,Ruida Xu,Jingzhi Shang,Lin Song,Kai Wang,Wei Huang,Ruihao Chen,Yiyun Fang,Hongqiang Wang,Zi-Qiang Rong","doi":"10.1002/anie.202513869","DOIUrl":"https://doi.org/10.1002/anie.202513869","url":null,"abstract":"Interface engineering has emerged as an effective strategy to address interface defects and energy level misalignment between the perovskite and hole transport layer (HTL). Herein, three novel multifunctional hole interface molecules with distinct substituents were designed to passivate defects at the perovskite/HTL interface. These molecules integrate hole-transporting groups with passivating units, enabling effective defect passivation, improved energy level alignment, and facilitating efficient carrier extraction. Among the three hole transport interface molecules (HTIMs), the 3-(3,6-bis(4-(bis(4-(methylthio)phenyl)amino)phenyl)-9H-carbazol-9-yl)hexan-1-amine hydroiodide (MeS-TPA-Cbz-HAI), comprising -MeS and HAI units, exhibited superior interface passivation capability and greater chemical compatibility with 2,2',7,7'-Tetrakis (N,N-di-p-methoxyphenylamine)-9,9'-spirobifluorene (Spiro-OMeTAD), leading to a reduction in defect density and enhanced hole transport. Consequently, the device based on MeS-TPA-Cbz-HAI achieved a notable power conversion efficiency (PCE) of 25.83%. Moreover, the unencapsulated device maintained 94% of its initial efficiency after 1000 hours of continuous operation under ambient conditions (30%-65% relative humidity), demonstrating remarkable long-term stability. This design strategy for hole interface molecules presents a promising avenue for achieving both high efficiency and operational stability in perovskite solar cells.","PeriodicalId":125,"journal":{"name":"Angewandte Chemie International Edition","volume":"11 1","pages":"e202513869"},"PeriodicalIF":16.6,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145338554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid Fabrication of Defective CuInP2S6 Nanosheets for Efficient CO2-to-Formate Conversion over Wide Current Densities. 在宽电流密度下快速制备有缺陷的CuInP2S6纳米片以实现二氧化碳到甲酸盐的高效转换。

IF 16.6 1区化学

Angewandte Chemie International Edition Pub Date : 2025-10-21 DOI: 10.1002/anie.202516041

Ya Liu,Meng Zhang,Xitang Qian,Guoyu Hou,Yicheng Li,Yanxiu Liu,Xingqiu Li,Shixian Guan,Junjie Chen,Minhua Shao,Yu Zhang

{"title":"Rapid Fabrication of Defective CuInP2S6 Nanosheets for Efficient CO2-to-Formate Conversion over Wide Current Densities.","authors":"Ya Liu,Meng Zhang,Xitang Qian,Guoyu Hou,Yicheng Li,Yanxiu Liu,Xingqiu Li,Shixian Guan,Junjie Chen,Minhua Shao,Yu Zhang","doi":"10.1002/anie.202516041","DOIUrl":"https://doi.org/10.1002/anie.202516041","url":null,"abstract":"Electrochemical CO2 reduction reaction (CO2RR) to produce value-added chemicals offers a promising approach to mitigate global warming and address the energy crisis. However, the development of highly selective and durable catalysts that perform reliably across varying operational conditions remains challenging. In this work, we report the synthesis of lithium-intercalated CuInP2S6 (Li-CIPS) with a layered structure via a one-step chemical vapor transport method. Compared to pristine CuInP2S6, lithium intercalation in Li-CIPS facilitates the rapid production of ultrathin CuInP2S6 nanosheets through simple soaking in water. Experimental and theoretical investigations reveal that these ultrathin Li-CIPS nanosheets contain abundant sulfur vacancies (Vs), which can substantially enhance the CO2RR activity while suppressing the competing hydrogen evolution reaction. As a result, the Li-CIPS catalyst achieves over 90% Faradaic efficiency (FE) for formate production across wide current densities ranging from 100 to 800 mA cm-2, and it maintains stable operation over 100 h at 200 mA cm-2. This study highlights a promising and selective AMP2X6-based electrocatalyst for efficient CO2-to-formate conversion in practical applications.","PeriodicalId":125,"journal":{"name":"Angewandte Chemie International Edition","volume":"129 1","pages":"e202516041"},"PeriodicalIF":16.6,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145331789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recoverable Fluorination Accelerates Ring-Opening Copolymerisation and Enables Post-Polymerisation-Modification of Polyesters. 可回收氟化加速开环共聚并使聚酯的聚合后改性成为可能。

IF 16.6 1区化学

Angewandte Chemie International Edition Pub Date : 2025-10-20 DOI: 10.1002/anie.202515104

Christoph Fornacon-Wood,Luca Steiner,Chengzhang Xu,Beate Paulus,Alex J Plajer

{"title":"Recoverable Fluorination Accelerates Ring-Opening Copolymerisation and Enables Post-Polymerisation-Modification of Polyesters.","authors":"Christoph Fornacon-Wood,Luca Steiner,Chengzhang Xu,Beate Paulus,Alex J Plajer","doi":"10.1002/anie.202515104","DOIUrl":"https://doi.org/10.1002/anie.202515104","url":null,"abstract":"Fluorination of polymers is a powerful strategy to enhance chemical or material properties yet integrating these benefits into degradable polymers remains underexplored. Here, we report a new class of fluorinated polyesters synthesized via ring-opening copolymerisation of pentafluoro styrene oxide with phthalic anhydride. The pendant C6F5 groups accelerate catalysis through fluorine-specific π-stacking interactions and improve obtained molecular weights compared to the non-fluorinated variant giving access to high weight materials (Mn,max. > 100 kg mol-1) with thermal and mechanical properties competitive with commodity plastics. These C6F5 groups then act as reactive handles in the material for efficient post-polymerisation modification (PPM) in solution, allowing fine-tuning of thermal, mechanical, optical, and solubility properties. PPM can even be performed on material surfaces, films and fibres can be selectively modified without dissolution. Lastly, degradation enables quantitative recovery of fluorine centres as sodium fluoride, offering a sustainable end-of-life option for the incorporated fluorine. Our work demonstrates how targeted fluorination of degradable polyesters can simultaneously enhance catalysis and unlock advanced material functionality.","PeriodicalId":125,"journal":{"name":"Angewandte Chemie International Edition","volume":"49 1","pages":"e202515104"},"PeriodicalIF":16.6,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145331725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Superatomic or Not? A Case Study on Isostructural Au3Ag2 and Au3Cu2 Nanoclusters. 是不是超原子？等结构Au3Ag2和Au3Cu2纳米团簇的实例研究

IF 16.6 1区化学

Angewandte Chemie International Edition Pub Date : 2025-10-20 DOI: 10.1002/anie.202519135

Yun-Ke Zhao,Zi-Rui Liu,Zhen-Chao Long,Wan-Qi Shi,Quan-Ming Wang

引用次数: 0

Metal-Hydroxide-Porphin Framework Membrane for Almost Perfectly Selective Li+ Retention. 金属-羟基-卟啉框架膜几乎完全选择性Li+保留。

IF 16.6 1区化学

Angewandte Chemie International Edition Pub Date : 2025-10-20 DOI: 10.1002/anie.202515502

Min Jian,Tingting Ma,Zixin Wang,Xuan Ding,Hongfei Gao,Shangfa Pan,Bo Wang,Lijun Yang,Lei Jiang,Jun Gao

引用次数: 0

Mechanism of the Stoltz-Grubbs (KOtBu/Et3SiH) Silylation: Single-Electron Transfer is the Missing Link between the Heterolytic and Radical Pathways. Stoltz-Grubbs （KOtBu/Et3SiH）硅基化的机理：单电子转移是杂解和自由基途径之间缺失的一环。

IF 16.6 1区化学

Angewandte Chemie International Edition Pub Date : 2025-10-20 DOI: 10.1002/anie.202517336

Ian D Jenkins,Ka Ho Chow,Elizabeth H Krenske

引用次数: 0

Quantitative Reactivity Profiling of Functional Arginine Residues in Human Cancer Cell Line Proteomes. 人类癌细胞蛋白质组中功能性精氨酸残基的定量反应性分析。

IF 16.6 1区化学

Angewandte Chemie International Edition Pub Date : 2025-10-20 DOI: 10.1002/anie.202515603

Wenbo Zhao,Yuliang Tang,Yihui Gao,Qi Ding,Qiang Li,Wenyang Li,Xiaoguang Lei

{"title":"Quantitative Reactivity Profiling of Functional Arginine Residues in Human Cancer Cell Line Proteomes.","authors":"Wenbo Zhao,Yuliang Tang,Yihui Gao,Qi Ding,Qiang Li,Wenyang Li,Xiaoguang Lei","doi":"10.1002/anie.202515603","DOIUrl":"https://doi.org/10.1002/anie.202515603","url":null,"abstract":"Arginine, a critical amino acid for protein structure and function, is involved in enzyme catalysis and macromolecular interactions. However, selectively targeting its reactive guanidine group has been challenging. Here, we utilized a probe, AP-1, based on phenylglyoxal, which demonstrated remarkable chemical selectivity and reactivity toward arginine residues. Using activity-based protein profiling (ABPP), we explored the human proteome across four cancer cell lines, obtaining quantitative data for approximately 17 000 arginine residues. This analysis led to the identification of several previously unreported hyperreactive arginine residues, including R43 of PKM, R171 of LDHA, R172 of LDHB, R341 of CKB, R168 of EIF4A1, and R118 of FUBP1, which are crucial for protein function. Notably, the mutation of CKB's R341 inhibited cell proliferation and migration by downregulating energy supply. We also introduced ArGO-LDHA-1, a covalent inhibitor targeting LDHA's hyperreactive arginine residues, showing potential to enhance chemotherapy efficacy. This work highlights the biological significance of arginine residues and provides a platform for large-scale profiling of arginine reactivity.","PeriodicalId":125,"journal":{"name":"Angewandte Chemie International Edition","volume":"54 1","pages":"e202515603"},"PeriodicalIF":16.6,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145331648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Heterogenised Molecular Electrocatalyst for Round-the-Clock Green Hydrogen Production by Solar-Electrolyser and Zinc-Air Batteries. 太阳能电解和锌-空气电池24小时绿色制氢的多相分子电催化剂。

IF 16.6 1区化学

Angewandte Chemie International Edition Pub Date : 2025-10-20 DOI: 10.1002/anie.202516482

Sukanta Saha,Yashwant Pratap Kharwar,Santanu Ghorai,Harshini V Annadata,Suhana Karim,Arnab Dutta

{"title":"A Heterogenised Molecular Electrocatalyst for Round-the-Clock Green Hydrogen Production by Solar-Electrolyser and Zinc-Air Batteries.","authors":"Sukanta Saha,Yashwant Pratap Kharwar,Santanu Ghorai,Harshini V Annadata,Suhana Karim,Arnab Dutta","doi":"10.1002/anie.202516482","DOIUrl":"https://doi.org/10.1002/anie.202516482","url":null,"abstract":"Solar energy-driven seawater electrolysis presents a sustainable method for producing high-purity green hydrogen to address the energy crisis. Developing a robust electrocatalyst for seawater splitting is crucial for green fuel production with solar integration. This study introduces a silica-anchored cobaloxime system as a multifunctional electrocatalyst for overall seawater splitting in conjunction with photovoltaic cells. The system achieves a solar-to-hydrogen generation efficiency of 14%, a power conversion efficiency of 17.4%, and a round-trip energy efficiency of 80%. A single-stack electrolyser using this catalyst produces an average of 0.82 mmol h-1 of green hydrogen and 0.44 mmol h-1 of oxygen, with a hydrogen conversion efficiency of approximately 80 kWh kg-1 under natural sunlight. The same catalyst also shows bidirectional O2 reduction and evolution activity, enabling solar energy storage through a rechargeable zinc-air battery (RZAB). A photovoltaic-RZAB-electrolyser triad was established for indirect green hydrogen production using stored renewable energy. The catalyst-containing RZAB system is effectively charged by a photovoltaic (PV) cell, achieving 25% energy efficiency, and facilitates seawater splitting without sunlight at an energy conversion efficiency of 84%. The strategic application of the catalyst as a multifunctional electrocatalyst enables sustainable green hydrogen production both during the day and night under practical conditions.","PeriodicalId":125,"journal":{"name":"Angewandte Chemie International Edition","volume":"17 1","pages":"e202516482"},"PeriodicalIF":16.6,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145331663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0