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Real-world safety and efficacy of lomitapide in homozygous familial hypercholesterolemia: interim report of special-use survey in Japan. 洛米他匹对同型家族性高胆固醇血症的实际安全性和疗效：日本特殊用途调查中期报告。
IF 1.7
Future cardiology Pub Date : 2024-02-01 Epub Date: 2024-02-29 DOI: 10.2217/fca-2023-0136
Mariko Harada-Shiba, Shigenori Haruna, Noriaki Kogawa
{"title":"Real-world safety and efficacy of lomitapide in homozygous familial hypercholesterolemia: interim report of special-use survey in Japan.","authors":"Mariko Harada-Shiba, Shigenori Haruna, Noriaki Kogawa","doi":"10.2217/fca-2023-0136","DOIUrl":"10.2217/fca-2023-0136","url":null,"abstract":"<p><p><b>Aim:</b> To evaluate the safety and efficacy of lomitapide in real-world clinical practice in Japan. <b>Patients & methods:</b> Interim analysis of 39 patients with homozygous familial hypercholesterolemia from an all-case surveillance study. <b>Results:</b> Median lomitapide dose (across 42 months) was 9.8 mg/day. 74 drug-related adverse events (AEs) were reported in 24 (61.5%) patients, including 14 (35.9%) with liver-related AEs, 19 (48.7%) with gastrointestinal disorders and 1 (2.6%) bleeding disorder. Lomitapide dose was reduced for 39.2% of drug-related AEs, withdrawn temporarily for 12.2%, and discontinued for 1 event (1.4%). Mean ± SD blood LDL-C level decreased from 225.9 ± 172.0 mg/dl (5.8 ± 4.5 mmol/l) predose to 159.4 ± 93.0 mg/dl (4.1 ± 2.4 mmol/l) at 12 months (p = 0.0245). <b>Conclusion:</b> This interim analysis suggests lomitapide is safe and effective in real-world clinical practice in Japan.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"67-80"},"PeriodicalIF":1.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139989785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipid lowering therapy: implications of recent clinical trials. 降脂疗法：近期临床试验的意义。
IF 1.7
Future cardiology Pub Date : 2024-02-01 Epub Date: 2024-01-16 DOI: 10.2217/fca-2023-0132
James M Backes, Daniel E Hilleman
{"title":"Lipid lowering therapy: implications of recent clinical trials.","authors":"James M Backes, Daniel E Hilleman","doi":"10.2217/fca-2023-0132","DOIUrl":"10.2217/fca-2023-0132","url":null,"abstract":"<p><p>Recent lipid lowering therapy trials have provided important insights on certain agents while also continuing to expand our understanding of atherosclerotic cardiovascular disease (ASCVD) risk. Findings from current trials include the impact of statin therapy on ASCVD among populations with HIV, the benefit of lowering low-density lipoprotein cholesterol with bempedoic acid among patients considered statin intolerant, the safety and efficacy of inclisiran over a 4-year period, another failed attempt for fibrates to reduce ASCVD risk, which omega-3 fatty to utilize for lowering cardiovascular events, 'n-of-1' trials evaluating statin intolerance, and how low-dose rosuvastatin compared with commonly utilized supplements for lowering lipid parameters. Such data help inform so clinicians can optimize lipid lowering therapy and improve ASCVD outcomes.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"89-98"},"PeriodicalIF":1.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139471991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Linking hearts and minds: understanding the cardiovascular impact of bipolar disorder. 心与心的联系：了解双相情感障碍对心血管的影响。
IF 1.6
Future cardiology Pub Date : 2024-01-01 Epub Date: 2024-10-09 DOI: 10.1080/14796678.2024.2408944
Darshini Shah, Bhupinder Singh, Fnu Varnika, Fremita Chelsea Fredrick, Anish Kumar Reddy Meda, Kanishk Aggarwal, Rohit Jain
{"title":"Linking hearts and minds: understanding the cardiovascular impact of bipolar disorder.","authors":"Darshini Shah, Bhupinder Singh, Fnu Varnika, Fremita Chelsea Fredrick, Anish Kumar Reddy Meda, Kanishk Aggarwal, Rohit Jain","doi":"10.1080/14796678.2024.2408944","DOIUrl":"10.1080/14796678.2024.2408944","url":null,"abstract":"<p><p>Bipolar disorder is a severe and recurring condition that has become a significant public health issue globally. Studies indicate a heightened risk and earlier onset of cardiovascular diseases among individuals with bipolar disorder, potentially increasing mortality rates. The chronic nature of bipolar disorder leads to disturbances across multiple systems, including autonomic dysfunction, over-activation of the hypothalamic-pituitary-adrenal axis and increased levels of peripheral inflammatory markers. These disruptions cause endothelial damage, the formation of plaques and blood clots, in addition to the medications used to treat bipolar disorder and genetic associations contributing to cardiovascular disease development. Understanding the complex interplay between bipolar disorder and cardiovascular events is essential for the prevention and effective management of cardiovascular conditions in individuals with bipolar disorder.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"709-718"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11552481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142389691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unlocking the mysteries of cryptogenic stroke: the role of long-term cardiac rhythm monitoring. 揭开隐源性中风的神秘面纱：长期心律监测的作用。
IF 1.6
Future cardiology Pub Date : 2024-01-01 Epub Date: 2024-07-23 DOI: 10.1080/14796678.2024.2377922
Panteleimon E Papakonstantinou
{"title":"Unlocking the mysteries of cryptogenic stroke: the role of long-term cardiac rhythm monitoring.","authors":"Panteleimon E Papakonstantinou","doi":"10.1080/14796678.2024.2377922","DOIUrl":"10.1080/14796678.2024.2377922","url":null,"abstract":"","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"431-433"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141747922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An analysis of retracted studies in cardiology in the last two decades. 对过去二十年心脏病学撤稿研究的分析。
IF 1.6
Future cardiology Pub Date : 2024-01-01 Epub Date: 2024-07-09 DOI: 10.1080/14796678.2024.2370698
Akash Sharma, Vidusha Karavadi, Harshini Suresh, Sowntappan Balasubramanian, Priyali Singh, Parteek Walia, U Venkatesh
{"title":"An analysis of retracted studies in cardiology in the last two decades.","authors":"Akash Sharma, Vidusha Karavadi, Harshini Suresh, Sowntappan Balasubramanian, Priyali Singh, Parteek Walia, U Venkatesh","doi":"10.1080/14796678.2024.2370698","DOIUrl":"10.1080/14796678.2024.2370698","url":null,"abstract":"<p><p><b>Background:</b> The aim of this study is to analyze retracted studies in cardiovascular field.<b>Methodology:</b> PubMed and Embase databases were used to identify retracted publications from 2002 to 2022. Various characteristics of articles were retrieved, and an analysis was performed using R software.<b>Results:</b> We finally included 979 articles. Authors from China have the highest number of retracted studies (35.5%), followed by the USA (22.1%), and Japan (4%). The most common causes of retraction are mistakes and honest errors (24.5%) and duplicate data (17.7%). From 2002 to 2022, there has been a significant increase in retracted studies and a decrease in the impact factor of journals, number of citations, and time to retraction.<b>Conclusion:</b> The trend of retracting publications in cardiology is increasing.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"471-477"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141558532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current and future landscape of cardiogeriatrics. 老年心脏病学的现状与未来。
IF 1.6
Future cardiology Pub Date : 2024-01-01 Epub Date: 2024-11-07 DOI: 10.1080/14796678.2024.2418761
Akshay Gaur, Abdallah Al-Mohammad, David Warriner
{"title":"Current and future landscape of cardiogeriatrics.","authors":"Akshay Gaur, Abdallah Al-Mohammad, David Warriner","doi":"10.1080/14796678.2024.2418761","DOIUrl":"10.1080/14796678.2024.2418761","url":null,"abstract":"","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"729-731"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Off-label uses of the Amplatzer Piccolo Occluder in children with congenital and acquired heart diseases. Amplatzer Piccolo 闭塞器在先天性和后天性心脏病患儿中的标示外使用。
IF 1.6
Future cardiology Pub Date : 2024-01-01 Epub Date: 2024-09-05 DOI: 10.1080/14796678.2024.2355057
Ashley Molloy, Neil Tailor, Ronak Naik, Nithya Swaminathan, Mohammed Absi, Anthony Merlocco, Jason Johnson, Shyam Sathanandam
{"title":"Off-label uses of the Amplatzer Piccolo Occluder in children with congenital and acquired heart diseases.","authors":"Ashley Molloy, Neil Tailor, Ronak Naik, Nithya Swaminathan, Mohammed Absi, Anthony Merlocco, Jason Johnson, Shyam Sathanandam","doi":"10.1080/14796678.2024.2355057","DOIUrl":"10.1080/14796678.2024.2355057","url":null,"abstract":"<p><p><b>Aim:</b> The Amplatzer Piccolo Occluder (APO) is approved for patent ductus arteriosus (PDA) occlusion in infants weighing >700 g but could offer versatility to treat other lesions.<b>Methods:</b> Retrospective review of children in whom APO was utilized for defects other than PDA between January 2022 and June 2023.<b>Results:</b> The APO was used in nine patients; three for ventricular septal defects, four with coronary fistulas, one for a ventricular pseudoaneurysm and one where APO deployed within a fenestration of a previously placed Amplatzer Septal Occluder. All nine patients had successful occlusions without complications.<b>Conclusion:</b> The APO is a versatile device that can be used to treat various small diameter lesions in children besides the PDA for which it is currently approved for.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"459-470"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11486072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142132435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex differences in Chronic Thromboembolic Pulmonary Hypertension. 慢性血栓闭塞性肺动脉高压的性别差异。
IF 1.6
Future cardiology Pub Date : 2024-01-01 Epub Date: 2024-08-19 DOI: 10.1080/14796678.2024.2385872
Shaunak Mangeshkar, Pawel Borkowski, Nikita Singh, Panagiotis Zoumpourlis, Maisha Maliha, Sanjana Nagraj, Amrin Kharawala, Robert Faillace
{"title":"Sex differences in Chronic Thromboembolic Pulmonary Hypertension.","authors":"Shaunak Mangeshkar, Pawel Borkowski, Nikita Singh, Panagiotis Zoumpourlis, Maisha Maliha, Sanjana Nagraj, Amrin Kharawala, Robert Faillace","doi":"10.1080/14796678.2024.2385872","DOIUrl":"10.1080/14796678.2024.2385872","url":null,"abstract":"<p><p>Chronic thromboembolic pulmonary hypertension (CTEPH) is an underdiagnosed sequela of acute pulmonary embolism with varied clinical presentation causing significant morbidity among the affected population. There exist important differences in the occurrence, clinical features and diagnosis of CTEPH between men and women, with women carrying a greater predisposition for the disease. Ongoing studies have also pointed out variations among men and women, in the treatment offered and long-term outcomes including mortality. This focused review article highlights important sex-associated differences in multiple aspects of CTEPH including its epidemiology, clinical features, diagnosis, treatment and outcomes as reported in current literature and highlights the need for future research to facilitate a clearer understanding of these differences.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"571-580"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coronary intravascular lithotripsy: the tombstone of coronary calcium. 冠状动脉血管内碎石术：冠状动脉钙化的墓碑。
IF 1.6
Future cardiology Pub Date : 2024-01-01 Epub Date: 2024-10-29 DOI: 10.1080/14796678.2024.2411191
Chandrashekar Bohra, Amit Gulati, Amit Hooda
{"title":"Coronary intravascular lithotripsy: the tombstone of coronary calcium.","authors":"Chandrashekar Bohra, Amit Gulati, Amit Hooda","doi":"10.1080/14796678.2024.2411191","DOIUrl":"10.1080/14796678.2024.2411191","url":null,"abstract":"","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"669-670"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11552475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142521561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Get pumped for the new year with Future Cardiology: welcome to volume 20. 未来心脏病学》为新的一年注入活力：欢迎阅读第 20 卷。
IF 1.7
Future cardiology Pub Date : 2024-01-01 Epub Date: 2024-01-15 DOI: 10.2217/fca-2023-0130
Ashling Cannon
{"title":"Get pumped for the new year with <i>Future Cardiology</i>: welcome to volume 20.","authors":"Ashling Cannon","doi":"10.2217/fca-2023-0130","DOIUrl":"10.2217/fca-2023-0130","url":null,"abstract":"","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"1-4"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139466415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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