Future cardiologyPub Date : 2024-12-01Epub Date: 2024-11-27DOI: 10.1080/14796678.2024.2434392
Asmaa Ahmed, Mahmoud Eisa, Andrew Takla, Sahej Arora, Mohamed Mohamed, Amir Hanafi, Scott Feitell
{"title":"Outcomes of mitral valve transcatheter edge to edge repair in patients with coronary chronic total occlusion.","authors":"Asmaa Ahmed, Mahmoud Eisa, Andrew Takla, Sahej Arora, Mohamed Mohamed, Amir Hanafi, Scott Feitell","doi":"10.1080/14796678.2024.2434392","DOIUrl":"10.1080/14796678.2024.2434392","url":null,"abstract":"<p><strong>Introduction: </strong>It remains unknown whether the concomitant coronary chronic total occlusion (CTO) would affect the outcomes of the Mitral valve Trans-catheter Edge to edge-to-edge repair (M-TEER) procedure.</p><p><strong>Methodology: </strong>Study population was extracted from the Nationwide Inpatient Sample Data using the International Classification of Diseases and clinical modifications/procedure coding system codes for M-TEER and CTO. Primary outcomes were in-hospital all-cause mortality and net cardiac periprocedural complications. Propensity matching was used to extract a matched control (M-TEER-CTO and M-TEER-No CTO).</p><p><strong>Results: </strong>A total of 48,835 cases of M-TEER were identified in the United States between January 2016 and December 2020, of whom 700 patients (1.5%) had the diagnosis of coronary total occlusion (CTO). The mean age of M-TEER patients was not significantly different between the two groups (76 vs. 75 years, <i>p</i> = 0.11); however, the CTO cohort had a higher percentage of males (66.72% vs. 53.41%, <i>p</i> = 0.002). M-TEER-CTO had higher odds of net all cardiac periprocedural complications (aOR 1.83,95% CI (1.17-2.84), <i>p</i> = 0.007) compared to the no-CTO group, however, there was no difference in in-hospital mortality (aOR 1.54, 95%CI (0.52-4.56), <i>p</i> = 0.43).</p><p><strong>Conclusions: </strong>Patients undergoing M-TEER with CTO had a higher incidence of net all cardiac periprocedural complications but similar mortality compared to those with no CTO.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"843-847"},"PeriodicalIF":1.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11730769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142727631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2024-12-01Epub Date: 2024-11-29DOI: 10.1080/14796678.2024.2433888
Adam C Livori, Lachlan Dalli, Stephen J Nicholls, Adam J Nelson
{"title":"Defining, measuring, and addressing medication non-adherence in cardiovascular disease.","authors":"Adam C Livori, Lachlan Dalli, Stephen J Nicholls, Adam J Nelson","doi":"10.1080/14796678.2024.2433888","DOIUrl":"10.1080/14796678.2024.2433888","url":null,"abstract":"","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"819-822"},"PeriodicalIF":1.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11731349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2024-12-01Epub Date: 2024-11-25DOI: 10.1080/14796678.2024.2433827
Ivo Deblier, Karl Dossche, Anthony Vanermen, Wilhelm Mistiaen
{"title":"Operation in the gray zone: is SAVR still useful in patients aged between 75 and 80 years?","authors":"Ivo Deblier, Karl Dossche, Anthony Vanermen, Wilhelm Mistiaen","doi":"10.1080/14796678.2024.2433827","DOIUrl":"10.1080/14796678.2024.2433827","url":null,"abstract":"<p><strong>Introduction: </strong>Aortic valve replacement is the only effective treatment for symptomatic aortic valve disease. Transcatheter implantation has been introduced as alternative for surgery (SAVR), but its penetration varied widely. For high-risk octogenarian patients, the advantages of TAVI are clear. Patients between 75 and 79 years of age could be considered as \"the gray zone.\"</p><p><strong>Methods: </strong>We compared the outcome of SAVR with or without concomitant procedures between patients younger than 75 versus 75-79 years for their preoperative profile, operative parameters, and postoperative outcomes.</p><p><strong>Results: </strong>Older patients had a higher risk score with more cardiovascular comorbidity and renal dysfunction. They required more concomitant CABG but less mitral valve repair. Cardiopulmonary bypass time was similar. In-hospital complication rates, need for blood transfusion, and length of stay in intensive care unit were higher in older patients. Thirty-day mortality was not significantly increased, Euroscore II overestimated mortality in both age groups. Age over 75 years was not an independent predictor for mortality. Need for emergent SAVR was only predictive in the older group. Long-term survival was acceptable. Age over 75 years was not the dominant predictor.</p><p><strong>Conclusions: </strong>SAVR remains a valid option to treat symptomatic aortic valve disease in the age group of 75-79.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"849-858"},"PeriodicalIF":1.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11734591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2024-12-01Epub Date: 2024-11-14DOI: 10.1080/14796678.2024.2426883
Anjali Agarwalla, Melissa A Austin, Nosheen Reza
{"title":"Genetics in clinical cardiology: the current state and opportunities ahead.","authors":"Anjali Agarwalla, Melissa A Austin, Nosheen Reza","doi":"10.1080/14796678.2024.2426883","DOIUrl":"10.1080/14796678.2024.2426883","url":null,"abstract":"","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"815-818"},"PeriodicalIF":1.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11730773/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2024-12-01Epub Date: 2024-11-18DOI: 10.1080/14796678.2024.2420552
Gorm Boje Jensen, Peter Schnohr, Carl J Lavie, James H O'Keefe
{"title":"Soft drinks, fish oil and atrial fibrillation.","authors":"Gorm Boje Jensen, Peter Schnohr, Carl J Lavie, James H O'Keefe","doi":"10.1080/14796678.2024.2420552","DOIUrl":"10.1080/14796678.2024.2420552","url":null,"abstract":"","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"807-810"},"PeriodicalIF":1.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11731244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142647335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2024-12-01Epub Date: 2024-12-04DOI: 10.1080/14796678.2024.2435205
Csaba A Dézsi, Judit Andréka, Amer M Sayour, Mónika Deák, Veronika Szentes, Zoltán Sebők, Zsolt Fi, Alexandru Achim, Zoltán Ruzsa
{"title":"Long-term clinical and angiographic outcome of T-and protrusion technique with ultrathin strut drug eluting stents.","authors":"Csaba A Dézsi, Judit Andréka, Amer M Sayour, Mónika Deák, Veronika Szentes, Zoltán Sebők, Zsolt Fi, Alexandru Achim, Zoltán Ruzsa","doi":"10.1080/14796678.2024.2435205","DOIUrl":"10.1080/14796678.2024.2435205","url":null,"abstract":"<p><strong>Objectives: </strong>Data about coronary bifurcations treated with ultrathin strut drug-eluting stents (DES) using T-and-protrusion (TAP) technique is limited.</p><p><strong>Methods: </strong>In this study, a total of 84 consecutive patients, who underwent bifurcation percutaneous coronary intervention (PCI) with TAP technique using Orsiro® DES (Biotronik, Berlin, Germany), were included. All pre- and post-procedural data, as well as 1- and 2-year follow-up angiograms, were analyzed. Primary endpoints were procedural success and target lesion failure (TLF); secondary endpoints were all-cause mortality and major adverse cardiac and cerebrovascular events (MACCE) during follow-up.</p><p><strong>Results: </strong>Procedural success was achieved in 100% of cases. TLF rate was higher in patients presented with acute coronary syndrome compared to the ones with chronic coronary syndrome (19% vs. 5% <i>p</i> = 0.09). All-cause mortality was 30% during follow-up, from which 26% was due to non-cardiovascular cause, and the MACCE rate was 46%.</p><p><strong>Conclusions: </strong>Coronary bifurcations treated with ultrathin strut DES showed good short-term results and were associated with acceptable cardiovascular mortality. However, in these long-term patients, the rate of MACCE and non-cardiovascular death were rather high.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"837-842"},"PeriodicalIF":1.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11731050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142768059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2024-12-01Epub Date: 2024-12-12DOI: 10.1080/14796678.2024.2440220
Obieda Altobaishat, Mohamed Abouzid, Mohammad Tanashat, Ahmed Mazen Amin, Mustafa Turkmani, Mohamed Abuelazm
{"title":"Rotational atherectomy with cutting balloon before stenting in severely calcified coronary lesions: a meta-analysis.","authors":"Obieda Altobaishat, Mohamed Abouzid, Mohammad Tanashat, Ahmed Mazen Amin, Mustafa Turkmani, Mohamed Abuelazm","doi":"10.1080/14796678.2024.2440220","DOIUrl":"10.1080/14796678.2024.2440220","url":null,"abstract":"<p><strong>Background: </strong>Rotational atherectomy (RA) has been proven to treat coronary artery calcification (CAC) during percutaneous coronary intervention (PCI).</p><p><strong>Purpose: </strong>This study evaluates the safety and efficacy of RA followed by cutting balloon angioplasty (ROTACUT) before stent placement in CAC.</p><p><strong>Methods: </strong>A systematic review and meta-analysis of randomized controlled trials and observational studies was conducted. PubMed, Web of Science, Scopus, and Cochrane were searched through January 2024. We used Stata version 17 to pool dichotomous data using risk ratio (RR) and continuous data using mean difference (MD), with a 95% confidence interval (CI).</p><p><strong>Results: </strong>Eight studies with 846 patients were included. There was no significant difference between ROTACUT and RA + bare balloons in major adverse cardiovascular events (MACE) (RR:0.60; 95%CI [0.31,1.16], <i>p</i> = 0.13), cardiac death (RR:1.32; 95%CI [0.42,4.14], <i>p</i> = 0.64), target vessel revascularization (TVR) (RR:1.89; 95%CI [0.40,8.84], <i>p</i> = 0.42), target lesion revascularization (TLR) (RR:0.83; 95%CI [0.39,1.79], <i>p</i> = 0.64), procedural duration (MD:0.78; 95%CI [-4.68,6.24], <i>p</i> = 0.78), stent thrombosis (RR:0.81; 95%CI [0.22,2.95], <i>p</i> = 0.75), and any procedure-related complications (RR:0.86; 95%CI [0.42,1.75], <i>p</i> = 0.68).</p><p><strong>Conclusion: </strong>ROTACUT and RA + bare balloons demonstrated similar efficacy and safety profiles regarding MACE, cardiac death, TVR, TLR, procedural duration, stent thrombosis, and all safety outcomes.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"859-870"},"PeriodicalIF":1.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11731055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Maternal cardiac arrest: the present and the future.","authors":"Sanjana Nagraj, Steve Kong","doi":"10.2217/fca-2024-0042","DOIUrl":"https://doi.org/10.2217/fca-2024-0042","url":null,"abstract":"","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140854942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Late recognition of cardiac implantable electronic device misplacement in left ventricle: a case report.","authors":"Fatemeh Bahrami, Babak Sattartabar, Farnoosh Larti, Mehrzad Rahmanian, Reza Mollazadeh","doi":"10.1080/14796678.2024.2363627","DOIUrl":"10.1080/14796678.2024.2363627","url":null,"abstract":"<p><p><b>Background:</b> Cardiac electronic device implantation may be associated with complications. <b>Case Summary:</b> This is a report of inadvertent implantation of implantable cardioverter-defibrillator lead through an unrecognized sinus venosus atrial septal defect into the left ventricle that was not diagnosed early after implantation. Six months later chest x-ray showed an abnormal lead course that was confirmed with echocardiography as to be in the left ventricle. Surgical removal of the implantable cardioverter-defibrillator lead, repair of atrial septal defect, and correction of abnormal pulmonary venous connections were performed. Meanwhile, follow-up of the patient receiving a new dual chamber permanent pacemaker from the contralateral side and discussion of the aforementioned complication are addressed. <b>Conclusion:</b> Early diagnosis of device implantation complication is of paramount importance and prevents potential catastrophic complications.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"269-274"},"PeriodicalIF":1.6,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11318706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141426684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2024-04-25Epub Date: 2024-07-10DOI: 10.1080/14796678.2024.2367860
Agnieszka Pawlos, Etienne Khoury, Daniel Gaudet
{"title":"Emerging therapies for refractory hypercholesterolemia: a narrative review.","authors":"Agnieszka Pawlos, Etienne Khoury, Daniel Gaudet","doi":"10.1080/14796678.2024.2367860","DOIUrl":"10.1080/14796678.2024.2367860","url":null,"abstract":"<p><p>Refractory hypercholesterolemia (RH) is characterized by the failure of patients to achieve therapeutic targets for low-density lipoprotein-cholesterol (LDL-C) despite receiving maximal tolerable doses of standard lipid-lowering treatments. It predominantly impacts individuals with familial hypercholesterolemia (FH), thereby elevating the risk of cardiovascular complications. The prevalence of RH is now recognized to be substantially greater than previously thought. This review provides a comprehensive insight into current and emerging therapies for RH patients, including groundbreaking genetic-based therapeutic approaches. The review places emphasis on the dependency of therapies on low-density lipoprotein receptors (LDLRs) and highlights the critical role of considering LDLR activity in RH patients for individualization of the treatment.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"317-334"},"PeriodicalIF":1.6,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11318688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}