Future cardiologyPub Date : 2024-01-01Epub Date: 2024-06-07DOI: 10.1080/14796678.2024.2355808
Zade Bihag, Haris Patail, Ali Ghani, Raymond G McKay, Jawad Haider, Asad Rizvi, Daniel Bruce Fram
{"title":"Spontaneous coronary artery dissection: a case series illustrating current challenges in diagnosis and treatment.","authors":"Zade Bihag, Haris Patail, Ali Ghani, Raymond G McKay, Jawad Haider, Asad Rizvi, Daniel Bruce Fram","doi":"10.1080/14796678.2024.2355808","DOIUrl":"10.1080/14796678.2024.2355808","url":null,"abstract":"<p><p>Spontaneous coronary artery dissection (SCAD) has been increasingly recognized in recent years as an important cause of acute coronary syndrome, myocardial infarction, and sudden death, especially among young women. However, due to the lack of clinical trials on SCAD, evidence-based guidance on management is currently lacking. Presented are four case studies that illustrate the recent insights and challenges in SCAD diagnosis and treatment.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"369-376"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11457618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141901427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2024-01-01Epub Date: 2024-08-12DOI: 10.1080/14796678.2024.2388472
Felice Gragnano, Vincenzo De Sio, Arturo Cesaro, Paolo Calabrò
{"title":"Ticagrelor monotherapy after acute coronary syndrome: lessons from the ULTIMATE-DAPT trial.","authors":"Felice Gragnano, Vincenzo De Sio, Arturo Cesaro, Paolo Calabrò","doi":"10.1080/14796678.2024.2388472","DOIUrl":"10.1080/14796678.2024.2388472","url":null,"abstract":"","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"591-593"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11520563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2024-01-01Epub Date: 2024-08-13DOI: 10.1080/14796678.2024.2387939
Sarah Meskal, Manrit Gill, Mohammad Reza Movahed, Mehrtash Hashemzadeh, Mehrnoosh Hashemzadeh
{"title":"Major depression is not associated with higher myocardial infarction rates: insights from a large database.","authors":"Sarah Meskal, Manrit Gill, Mohammad Reza Movahed, Mehrtash Hashemzadeh, Mehrnoosh Hashemzadeh","doi":"10.1080/14796678.2024.2387939","DOIUrl":"10.1080/14796678.2024.2387939","url":null,"abstract":"<p><p><b>Background:</b> Depression has been suggested to increase the risk of cardiovascular disease, but many studies assessed depression after heart disease onset. This study evaluated the association between depression and myocardial infarction (MI) using a large inpatient database.<b>Methods:</b> We analyzed patients from the National Inpatient Sample hospitals from 2005 to 2020, selecting those aged >30 with ICD-9 and ICD-10 codes for segment elevation (ST) elevation myocardial infarction (STEMI), non-ST elevation myocardial elevation (NSTEMI) and major depression.<b>Results:</b> Our data included 4413,113 STEMI patients (224,430 with depression) and 10,421,346 NSTEMI patients (437,058 with depression). No significant association was found between depression and MI. For STEMI, the 2005 odds ratio was 0.12 (95% CI: 0.10-0.15, <i>p</i> < 0.001) and the 2020 odds ratio was 0.71 (95% CI: 0.69-0.73, <i>p</i> < 0.001). Similar patterns were observed for NSTEMI.<b>Conclusion:</b> Depression may not independently be a significant risk factor for MI.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"619-625"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11520533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141970979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2024-01-01Epub Date: 2024-05-03DOI: 10.1080/14796678.2024.2341535
Sanjana Nagraj, Steve Kong
{"title":"Maternal cardiac arrest: the present and the future.","authors":"Sanjana Nagraj, Steve Kong","doi":"10.1080/14796678.2024.2341535","DOIUrl":"10.1080/14796678.2024.2341535","url":null,"abstract":"","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":"20 3","pages":"99-101"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11216517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141456288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2024-01-01Epub Date: 2024-07-05DOI: 10.1080/14796678.2024.2365552
Mehdi Hassanpour, Reza Rahbarghazi, Aysa Rezabakhsh, Rasa Khodavirdilou, Akbar Darbin, Elmira Zolali, Nasser Safaei
{"title":"Relationship between angiogenesis biomarker endocan and apolipoproteins in patients with acute myocardial infarction.","authors":"Mehdi Hassanpour, Reza Rahbarghazi, Aysa Rezabakhsh, Rasa Khodavirdilou, Akbar Darbin, Elmira Zolali, Nasser Safaei","doi":"10.1080/14796678.2024.2365552","DOIUrl":"10.1080/14796678.2024.2365552","url":null,"abstract":"<p><p><b>Aim:</b> In the current study, serum levels of endocan in patients attended with ST-elevation myocardial infarction, as well as the possible correlation with apolipoprotein-A1 (APO-A1) and APO-B were investigated.<b>Materials & methods:</b> In 80 men, endocan, cTnI, APO-A1, and APO-B levels were measured. Finally, the correlation of endocan with APO-A1, APO-B, and APO-B/ APO-A1 ratio was assessed.<b>Results:</b> Significant changes in APO-A1, APO-B, endocan levels, and APO-B/APO-A1 ratio were found in acute myocardial infarction cases compared with the control arm (p < 0.05). In addition, our finding showed a significant correlation between APO-B and endocan levels, but not APO-A.<b>Conclusion:</b> High endocan level is an independent indicator of endothelial dysfunction and ischemic cardiovascular conditions, which could be related to APO-B.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"555-561"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11486116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141534195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2024-01-01Epub Date: 2024-07-23DOI: 10.1080/14796678.2024.2357946
Parker O'Neill, Brian Osler, Joey Junarta, Tal Zivan, Gerard Hoeltzel, Robert Ford, Phyllis Flomenberg, Arnold Greenspon, Praveen Mehrotra
{"title":"Combined transcatheter vegetectomy and leadless pacemaker implantation for endocarditis and complete heart block.","authors":"Parker O'Neill, Brian Osler, Joey Junarta, Tal Zivan, Gerard Hoeltzel, Robert Ford, Phyllis Flomenberg, Arnold Greenspon, Praveen Mehrotra","doi":"10.1080/14796678.2024.2357946","DOIUrl":"10.1080/14796678.2024.2357946","url":null,"abstract":"<p><p>We describe a case of culture-negative right-sided endocarditis for which simultaneous transcatheter vegetectomy was performed with leadless pacemaker implantation and removal of a temporary externalized pacing system. The patient did not have a recurrence of endocarditis highlighting the safety and efficacy of same-procedure vegetation removal and pacemaker implantation. This report documents a novel approach for the treatment of cardiac implantable electronic device-associated endocarditis in poor surgical candidates who are pacemaker-dependent.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"359-363"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11457670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141747919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2024-01-01Epub Date: 2023-12-21DOI: 10.2217/fca-2023-0030
Maurizio Maria Coronelli, Francesca Coppi, Anna Vittoria Mattioli
{"title":"Inflammation, atherosclerosis and hypertension: the impact of depression and stress on their complex relationship.","authors":"Maurizio Maria Coronelli, Francesca Coppi, Anna Vittoria Mattioli","doi":"10.2217/fca-2023-0030","DOIUrl":"10.2217/fca-2023-0030","url":null,"abstract":"<p><p>This future perspective analyzes the complex relationship between inflammation and atherosclerosis and arterial hypertension. The involvement of inflammation in atherosclerosis has led to research therapies that target inflammation to prevent or treat cardiovascular disease. This aspect has recently been included in the treatment management of residual cardiovascular risk. The recent pandemic has exacerbated cardiovascular risk both through an increase in unhealthy lifestyle behaviors and through the reduction of cardiovascular screening. What actions to take? Primary prevention campaigns for healthy subjects with specific attention to young people.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"27-33"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138835911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2024-01-01Epub Date: 2024-01-08DOI: 10.2217/fca-2022-0117
Ali Fatehi Hassanabad, Tiffany Kim, Corey Adams
{"title":"A rare and unique case: aortic valve replacement in a young adult with a stenotic unicommissural unicuspid aortic valve.","authors":"Ali Fatehi Hassanabad, Tiffany Kim, Corey Adams","doi":"10.2217/fca-2022-0117","DOIUrl":"10.2217/fca-2022-0117","url":null,"abstract":"<p><p>Unicuspid aortic valve (UAV) is a rare congenital cardiac anomaly. There are two forms of UAV, including unicuspid acommissural and unicuspid unicommissural. Definitive management for UAV is surgical intervention, but due to the rarity of UAV, the long-term surgical outcomes as well as overall prognosis are not known. Here, we present the case of a 19-year-old patient who was found to have a UAV prenatally and underwent a mechanical aortic valve replacement through an upper hemi-sternotomy due to elevated aortic stenosis gradients and presence of symptoms.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"5-10"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139377454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2024-01-01Epub Date: 2024-08-05DOI: 10.1080/14796678.2024.2383500
Sammudeen Ibrahim, Saint-Martin Allihien, Samuel Dadzie, Stanley E Atencah, Inemesit Akpan
{"title":"A fatal case of cabozantinib-induced cardiomyopathy.","authors":"Sammudeen Ibrahim, Saint-Martin Allihien, Samuel Dadzie, Stanley E Atencah, Inemesit Akpan","doi":"10.1080/14796678.2024.2383500","DOIUrl":"10.1080/14796678.2024.2383500","url":null,"abstract":"<p><p>Cabozantinib, a multi-kinase receptor inhibitor, is utilized in the treatment of advanced malignancies such as metastatic renal cancers. While rare, cabozantinib-induced cardiotoxicity has emerged as a recognized adverse effect with potentially reversible outcomes. We report the case of a 55-year-old male who developed fatal cardiomyopathy 4 months after initiating cabozantinib therapy. Despite its rarity, cardiomyopathy after initiation of cabozantinib can be lethal if not diagnosed early. This case underscores a significant gap in the surveillance of patients treated with newer agents like cabozantinib. Larger observational studies are needed to assess the prevalence and impact of cardiomyopathy after initiation of cabozantinib therapy, and to determine the cost-effectiveness of early surveillance protocols.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"537-541"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141888939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2024-01-01Epub Date: 2024-08-14DOI: 10.1080/14796678.2024.2388478
Muhammad Hamayal, Warda Shahid, Chaudhary Humayun Akhtar, Fnu Shekiba, Iqra Iftikhar, Muhammad Danyal Tahir, Muhammad Awwab, Saima Hussain, Saman Naeem, Momina Hafeez
{"title":"Risk of cardiovascular outcomes with bempedoic acid in high-risk statin intolerant patients: a systematic review and meta analysis.","authors":"Muhammad Hamayal, Warda Shahid, Chaudhary Humayun Akhtar, Fnu Shekiba, Iqra Iftikhar, Muhammad Danyal Tahir, Muhammad Awwab, Saima Hussain, Saman Naeem, Momina Hafeez","doi":"10.1080/14796678.2024.2388478","DOIUrl":"10.1080/14796678.2024.2388478","url":null,"abstract":"<p><p><b>Aim:</b> Statin intolerance and myopathy is a major issue with prolonged use of statins myopathy. Bempedoic acid can be a good alternative for those intolerant to statins. This systematic review aims to observe incidence of major adverse cardiovascular events (MACE) and other adverse events, in high-risk statin intolerant patients receiving bempedoic acid.<b>Methods:</b> Literature search was conducted via Google Scholar, Science Direct and PubMed, after which screening, selection and data extraction of articles was done. Meta-analysis was performed on RevMan 5.4. Subgroup analysis was also conducted and heterogeneity was evaluated. Risk of bias was performed using ROB2 assessment scale. (CRD42024536827).<b>Results:</b> Only six randomized controlled trials were used in final analysis consisting of 17,844 patients. Treatment with bempedoic acid was associated with a reduced risk of MACE compared with placebo (RR 0.86; 95% CI [0.79, 0.94] <i>p</i> = 0.0005), with myocardial infarction significantly reduced. Incidence of adverse effects was increased with bempedoic acid (RR: 1.02; 95% [1.00, 1.03] <i>p</i> = 0.01) but no significant difference was observed. Incidence of myalgia was reduced in bempedoic group as well.<b>Conclusion:</b> Bempedoic acid is a safe and effective alternative to statins in high-risk patients intolerant to statins, decreasing the risk of MACE.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"639-650"},"PeriodicalIF":1.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11520570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}