Future Science OAPub Date : 2023-08-08eCollection Date: 2023-10-01DOI: 10.2144/fsoa-2023-0056
Mera A Ababneh, Malak Alkhalil, Abeer Rababa'h
{"title":"The prevalence, risk factors and lifestyle patterns of Jordanian females with premenstrual syndrome: a cross-sectional study.","authors":"Mera A Ababneh, Malak Alkhalil, Abeer Rababa'h","doi":"10.2144/fsoa-2023-0056","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0056","url":null,"abstract":"<p><strong>Aim: </strong>The study aims to assess factors associated with premenstrual syndrome (PMS) and the frequency of using painkillers to relieve premenstrual pain.</p><p><strong>Methods: </strong>This is a cross-sectional study of 1580 premenopausal women. An online self-administered questionnaire consists of sociodemographics, and the diagnostic criteria using the Arabic Premenstrual Syndrome Scale (A-PMS).</p><p><strong>Results: </strong>The prevalence of PMS among Jordanian females was 94%. Moreover, a significant correlation was found between several factors, including BMI, family history of PMS, smoking, and herbal tea consumption and the psychological, physical and behavioral symptoms of PMS. Furthermore, analgesic use for pain relief and food cravings were significantly associated with psychological, physical and behavioral PMS symptoms.</p><p><strong>Conclusion: </strong>PMS is highly prevalent and affects women in different life aspects.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 9","pages":"FSO889"},"PeriodicalIF":2.5,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41172968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A rare cause of spontaneous hemoperitoneum: intra-abdominal vein rupture.","authors":"Moufida Mahmoudi, Ghada Gharbi, Amal Khsiba, Amine Jallouli, Asma Ben Mohamed, Manel Yakoubi, Mouna Medhioub, Lamine Hamzaoui, Khaled Bouzaidi, Mohamed Mousadek Azouz","doi":"10.2144/fsoa-2023-0029","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0029","url":null,"abstract":"<p><strong>Aim: </strong>Ruptures of the intra-abdominal vein causing a spontaneous hemoperitoneum in cirrhotic patients is a rare condition. However, diagnosis must be considered early in cirrhotic patients with hematic ascites as a delayed diagnosis with hemodynamic instability is associated with a poor prognosis.</p><p><strong>Case report: </strong>We present the case of a 54-year-old cirrhotic patient who presented a spontaneous hemoperitoneum due to the rupture of the intra-abdominal vein that was diagnosed during exploratory laparoscopy.</p><p><strong>Conclusion: </strong>Early diagnosis and management of spontaneous hemoperitoneum due to the rupture of intra-abdominal vein helps improve its prognosis.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 9","pages":"FSO891"},"PeriodicalIF":2.5,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41122599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future Science OAPub Date : 2023-08-08eCollection Date: 2023-10-01DOI: 10.2144/fsoa-2023-0086
Zhongqi Zhang, Tianmiao Zhang, Rongcheng Zhang, Zhengbao Zhang, Shengkui Tan
{"title":"Migrasomes and tetraspanins in hepatocellular carcinoma: current status and future prospects.","authors":"Zhongqi Zhang, Tianmiao Zhang, Rongcheng Zhang, Zhengbao Zhang, Shengkui Tan","doi":"10.2144/fsoa-2023-0086","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0086","url":null,"abstract":"<p><p>In recent years, many studies have attempted to clarify the formation, structure and biological function of migrasomes, which are defined as specialized organelles formed by the tips and intersections of Retraction Fibrils during cell migration. It has confirmed that migrasomes were involved in various critical biological processes and diseases, and has became a new research hotspot. In this paper, we reviewed the formation and biological functions of migrasomes, explored the relationship between migrasomes, tetraspanins and hepatocellular carcinoma and discussed the potential applications of migrasomes in hepatocellular carcinoma.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 9","pages":"FSO890"},"PeriodicalIF":2.5,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41115853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future Science OAPub Date : 2023-08-08eCollection Date: 2023-10-01DOI: 10.2144/fsoa-2023-0102
Mohammad Daher, Ziad Zalaquett, Elio Mekhael, Marven Aoun, Ralph Chalhoub, Majd Abdo, Marc Aoude, Sami Abi Farraj, Ali Ghoul, Jean Tarchichi, Joe Rassi, Amer Sebaaly, Viviane Trak-Smayra, Carole Kesrouani, Hampig-Raphaël Kourie, Ismat Ghanem
{"title":"Epidemiology of bone tumors in Lebanon: a retrospective study from 2000 to 2022 at a tertiary center.","authors":"Mohammad Daher, Ziad Zalaquett, Elio Mekhael, Marven Aoun, Ralph Chalhoub, Majd Abdo, Marc Aoude, Sami Abi Farraj, Ali Ghoul, Jean Tarchichi, Joe Rassi, Amer Sebaaly, Viviane Trak-Smayra, Carole Kesrouani, Hampig-Raphaël Kourie, Ismat Ghanem","doi":"10.2144/fsoa-2023-0102","DOIUrl":"10.2144/fsoa-2023-0102","url":null,"abstract":"<p><strong>Aim: </strong>Bone tumors are rare and have an uneven geographic distribution.</p><p><strong>Methods: </strong>730 patients diagnosed with bone tumors were included in this retrospective analysis.</p><p><strong>Results: </strong>With a 64% rate of malignancy, the most common tumors were metastasis (40%) mostly in the axial skeleton, Osteosarcoma (9%) mostly in the femur, Osteochondroma (8%) mostly in the femur, giant cell tumors (7%) mostly in the knee, and Ewing's sarcoma (6%) mostly in the axial skeleton.</p><p><strong>Conclusion: </strong>Even though a some of the tumors have a predilection for certain localizations in the human body, they may differ in the middle-eastern population. One must also pay attention to the higher rates of malignancies as compared with other cohorts.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 9","pages":"FSO886"},"PeriodicalIF":2.5,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41105806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between hemoglobin variants and laboratory outcomes in patients infected with <i>P. falciparum</i> from South West Uganda.","authors":"Hope Onohuean, Fanny Eseohe Onohuean, Ebere Emilia Ayogu","doi":"10.2144/fsoa-2022-0067","DOIUrl":"https://doi.org/10.2144/fsoa-2022-0067","url":null,"abstract":"<p><strong>Aims: </strong>We assess the relationship between various hemoglobin variants and some hematological parameters packed cell volume, white blood cells (PCV, WBC) and parasitemia level of patients with malaria in the southwestern, Uganda.</p><p><strong>Methods: </strong>Patient were enrolled by rapid diagnostic tests (RDTs), confirmed by microscopy, and laboratory outcomes were determined.</p><p><strong>Results: </strong>Patients positive for malaria RDTs were 155, microscopic-confirmed <i>P. falciparum</i> parasites were 95 (61.29%) having hemoglobin variants HbAA and HbAS; 75 (78.95%) and 13 (13.68%), respectively. The laboratory outcomes showed mean, PCV (32.19 ± 4.83), WBC (5831.66 ± 2888.29) and <i>P. falciparum</i> parasitaemia density (32,605.45 ± 14031), while the hemoglobin variants mean values AA (39,008.85 ± 31,261.56), AC (15908 ± 10173.48), AS (16,561.46 ± 15,380.93), SC (30,524 ± 0.000) and SS(1652 ± 0.000) were significantly different from the total population (34,321.5 ± 21,924.26) parasite-density.</p><p><strong>Conclusion: </strong>Patients with hemoglobin variants HbAA had a significantly higher parasite-carrying capacity and PCV levels.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 7","pages":"FSO888"},"PeriodicalIF":2.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9867656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yi Kuang, Wenjing Shen, Xiaodong Ma, Ziwei Wang, Rui Xu, Qingqing Rao, Shengxiang Yang
{"title":"<i>In silico</i> identification of natural compounds against SARS-CoV-2 main protease from Chinese herbal medicines.","authors":"Yi Kuang, Wenjing Shen, Xiaodong Ma, Ziwei Wang, Rui Xu, Qingqing Rao, Shengxiang Yang","doi":"10.2144/fsoa-2023-0055","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0055","url":null,"abstract":"<p><strong>Aims: </strong>To determine natural compounds with inhibitory effects toward SARS-CoV-2 Mpro from Chinese herbal medicines.</p><p><strong>Materials & methods: </strong>∼1200 natural compounds from 19 Chinese herbal medicines were collected. Computational methods including molecular docking, drug-likeness assessment, molecular dynamics simulation and molecular mechanics Poisson-Boltzmann surface area analysis were combined to obtain potent inhibitors against SARS-CoV-2 Mpro.</p><p><strong>Results: </strong>Top 20 compounds mainly originated from <i>Ranunculus ternatus</i> and <i>Picrasma quassioides</i> exhibited low binding free energies which below -9.0 kcal/mol. Compounds Japonicone G and Picrasidine T were obtained with favorable drug-likeness. Moreover, the complex of Japonicone G and Mpro had prominent stability.</p><p><strong>Conclusion: </strong>Natural compound Japonicone G is highly promising as a potent inhibitor against SARS-CoV-2 for further study.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 7","pages":"FSO873"},"PeriodicalIF":2.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9867659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shaza M Elhusseiny, Abraam S Bebawy, Bishoy T Saad, Khaled M Aboshanab
{"title":"Insights on monkeypox disease and its recent outbreak with evidence of nonsynonymous missense mutation.","authors":"Shaza M Elhusseiny, Abraam S Bebawy, Bishoy T Saad, Khaled M Aboshanab","doi":"10.2144/fsoa-2023-0048","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0048","url":null,"abstract":"<p><p>The 2022 monkeypox outbreak has created a new global health threat and pandemic. Monkeypox virus is a descendant of the genus <i>Orthopoxvirus</i>, producing a febrile skin rash disease in humans. Monkeypox is zoonotic transmitted and transmitted from human to human in several ways. Even though this disease is self-limited, it creates important community health worries due to its inconvenience and widespread complications. Herein, we discussed the up-to-date current situation of monkeypox regarding its epidemiology, clinical manifestations, current in-use therapeutics, necessary protective measures, and response to potential occurrences considering the recent pandemic. Also, in this review, a comparative genomic analysis of the recent circulating strains that have been recovered from various countries including, Egypt, USA, Spain, Japan and South Africa has been investigated.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 7","pages":"FSO877"},"PeriodicalIF":2.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9865666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ruqaiyyah Siddiqui, Adel B Elmoselhi, Naveed Ahmed Khan
{"title":"Space medicine: gut microbiome of hardy species is a potential source to counter disorders during space travel.","authors":"Ruqaiyyah Siddiqui, Adel B Elmoselhi, Naveed Ahmed Khan","doi":"10.2144/fsoa-2023-0060","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0060","url":null,"abstract":"<p><p>It is proposed that gut microbiome of species like cockroaches may offer a potential source of novel mechanisms/molecules that can be translated into humans to safeguard astronauts against stressors of the space environment during deep space exploration missions.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 7","pages":"FSO868"},"PeriodicalIF":2.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9867660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of smoking cessation interventions for smokers with Crohn's disease: a systematic review.","authors":"Sahar Nasr, Ilyess Nsiri, Manel Ben Fredj","doi":"10.2144/fsoa-2022-0049","DOIUrl":"https://doi.org/10.2144/fsoa-2022-0049","url":null,"abstract":"<p><strong>Aims: </strong>Smoking cessation (SC) in Crohn's disease (CD) is widely accepted to be the most important modifiable factor to improve outcomes in these patients. We aimed in this review to provide a summary of the evidence base regarding the effectiveness of SC interventions in patients with CD.</p><p><strong>Materials & methods: </strong>The following databases were systematically searched from inception to February 2022: PubMed, Google Scholar and Cochrane Library.</p><p><strong>Results: </strong>Overall, five articles met the research criteria. Studies sample size ranged from 17 to 474 patients. At the outcome level, the abstinence rates ranged from 14.8 to 42% and was ≤25% in four studies. The three studies with control groups did not report statistically higher SC rates in the intervention groups. No predictors of interventions success were identified in this review.</p><p><strong>Conclusion: </strong>Implementation and evaluation of tailored SC interventions for CD patients must be promptly addressed in further studies.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 7","pages":"FSO870"},"PeriodicalIF":2.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10223136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abbas Bader, Madeline Begemann, Ammar Al-Obaidi, Muhammad Hamza Habib, Faiz Anwer, Shahzad Raza
{"title":"Ocular complications of antineoplastic therapies.","authors":"Abbas Bader, Madeline Begemann, Ammar Al-Obaidi, Muhammad Hamza Habib, Faiz Anwer, Shahzad Raza","doi":"10.2144/fsoa-2022-0081","DOIUrl":"https://doi.org/10.2144/fsoa-2022-0081","url":null,"abstract":"<p><p>Ocular complications of antineoplastic agents can have a profound effect on the quality of life of cancer patients. New oncologic treatments like monoclonal antibodies, immunotherapies, antibody-drug conjugates, checkpoint inhibitors and growth factor receptors have resulted in increased ocular complications. These ocular complications differs in respect to distinct mechanisms of actions and lead to significant challenges in the management of cancer patients. In this review, we reviewed literature, clinical studies and cases detailing ocular complications due to administration of antineoplastic agents and emphasized the need for communication between oncologists and ophthalmologists toward early detection and management of ocular complications.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 7","pages":"FSO871"},"PeriodicalIF":2.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9867657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}