Future Science OA最新文献_第9页

Prevalence of pain and literacy in patients with diabetic peripheral neuropathy in Portugal: the REGENERAR registry study. 葡萄牙糖尿病周围神经病变患者的疼痛患病率和读写能力：REGENERAR注册研究

IF 2.1

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-08-11 DOI: 10.1080/20565623.2025.2527503

Filipe Antunes, Emanuel Airosa, Samara Rubio Rodriguez, Igor Faria, Diogo Anes, Teresa Cruz, José Miguel Oliveira, João Simões, Lisandra Dias, Carina Faria, Pedro Xavier, Patrícia Alves, Jacinta Pereira, Inês Lima, Raul Marques Pereira

{"title":"Prevalence of pain and literacy in patients with diabetic peripheral neuropathy in Portugal: the REGENERAR registry study.","authors":"Filipe Antunes, Emanuel Airosa, Samara Rubio Rodriguez, Igor Faria, Diogo Anes, Teresa Cruz, José Miguel Oliveira, João Simões, Lisandra Dias, Carina Faria, Pedro Xavier, Patrícia Alves, Jacinta Pereira, Inês Lima, Raul Marques Pereira","doi":"10.1080/20565623.2025.2527503","DOIUrl":"10.1080/20565623.2025.2527503","url":null,"abstract":"Aim: The REGENERAR registry study aimed to assess the prevalence of pain among Diabetic Peripheral Neuropathy (DPN) patients and to evaluate their health literacy and quality of life.Methods: REGENERAR was a prospective, multicentric registry study conducted in primary healthcare units across Portugal. Adults with DPN were enrolled between April and September 2023. Sociodemographic and clinical information, including pain, neuropathic pain, literacy and quality of life were collected at inclusion visit (V1) and end-of-study visit (V2).Results: The study enrolled 127 patients, 120 of whom completed V2. At V1, 77.5% of participants reported pain (61.7% at V2, p < 0.001), with neuropathic pain prevalence, assessed by clinical findings and result of DN4 questionnaire, being 48.3% at V1 and 46.7% at V2. Patient literacy on pain as a diabetes mellitus symptom improved from V1 to V2. Quality of life remained stable but suboptimal, with a median score of 70/100 on the EQ-5D-5L scale.Conclusion: The REGENERAR registry highlights a high prevalence of pain among DPN patients in Portugal, exceeding international figures, but consistent with literature concerning neuropathic pain. It also identifies critical gaps in both patient and healthcare provider literacy. Addressing these gaps could improve disease management and quality of life.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2527503"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12341050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144816343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immunoglobulin free light chain-κ in association with NT-proBNP levels after smoking cessation. 戒烟后免疫球蛋白游离轻链κ与NT-proBNP水平的关系

IF 2.1

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-09-07 DOI: 10.1080/20565623.2025.2527504

Maki Komiyama, Swati Mittal, Hajime Yamakage, Noriko Satoh-Asahara, Hiromichi Wada, Akihiro Yasoda, Masafumi Funamoto, Yasufumi Katanasaka, Yoichi Sunagawa, Tatsuya Morimoto, Yuko Takahashi, Takeo Nakayama, Akira Matsumori, Koji Hasegawa

{"title":"Immunoglobulin free light chain-κ in association with NT-proBNP levels after smoking cessation.","authors":"Maki Komiyama, Swati Mittal, Hajime Yamakage, Noriko Satoh-Asahara, Hiromichi Wada, Akihiro Yasoda, Masafumi Funamoto, Yasufumi Katanasaka, Yoichi Sunagawa, Tatsuya Morimoto, Yuko Takahashi, Takeo Nakayama, Akira Matsumori, Koji Hasegawa","doi":"10.1080/20565623.2025.2527504","DOIUrl":"10.1080/20565623.2025.2527504","url":null,"abstract":"Background: Smoking induces inflammation in the heart and intima layer of blood vessels by activating nuclear factor kappa B, which controls the transcription of immunoglobulin free light chain (FLC)-κ. FLC levels are indicative of higher mortality in the overall population and poorer prognoses in cardiovascular diseases. This study aimed to analyze the effect of smoking cessation (SC) on the levels of FLCs and markers of inflammation and heart failure.Research design and methods: This study enrolled first visit smokers determined to quit smoking at our hospital. Levels of various clinical parameters, including inflammatory markers, such as FLC, were measured on their first clinic visit and after 3 months of successful SC.Results: Body-mass-index (BMI) values significantly increased from baseline to 3 months after SC (n = 76, p = 0.004). Conversely, the levels of inflammatory markers including FLC-κ, neutrophil-to-lymphocyte-ratio and NT-proBNP significantly decreased after SC (p = 0.042, p = 0.024 and p = 0.030, respectively). Proportional changes in FLC-κ levels observed after SC showed a significant correlation with those of C-reactive-protein (r = 0.349, p = 0.002) and NT-proBNP (r = 0.332, p = 0.005) levels in the successful SC group.Conclusions: Levels of FLC-κ, a novel inflammatory and cardiovascular risk biomarker, decreased significantly after SC in association with NT-proBNP, suggesting the SC-induced reduction of cardiac load as well as a decrease in inflammation.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2527504"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12416185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Web-based predictive tool for vaginal and vulvar melanomas: a machine learning study. 基于网络的阴道和外阴黑色素瘤预测工具：一项机器学习研究。

IF 2.1

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-09-17 DOI: 10.1080/20565623.2025.2540747

Sakhr Alshwayyat, Zena Haddadin, Sara Haddadin, Mustafa Alshwayyat, Tala Abdulsalam Alshwayyat, Muna Talafha, Hamdah Hanifa, Jihan Muhaidat

{"title":"Web-based predictive tool for vaginal and vulvar melanomas: a machine learning study.","authors":"Sakhr Alshwayyat, Zena Haddadin, Sara Haddadin, Mustafa Alshwayyat, Tala Abdulsalam Alshwayyat, Muna Talafha, Hamdah Hanifa, Jihan Muhaidat","doi":"10.1080/20565623.2025.2540747","DOIUrl":"10.1080/20565623.2025.2540747","url":null,"abstract":"Background: One in every 41 women develops malignant melanoma in their lifetime, with noncutaneous melanomas arising in areas such as the genitourinary (GU) system being particularly rare and aggressive. We used machine learning (ML) to build prognostic models for vaginal (VaM) and vulvar (VuM) melanomas and developed the first predictive web-based tool for survival in these cancers.Methods: We leveraged the SEER database (2000-2020) to assemble our cohort and extract relevant clinical and demographic variables. Prognostic factors were screened using univariate and multivariate Cox proportional hazards regression analyses. Subsequently, we developed five machine-learning classifiers to predict 5-year survival. The discrimination of each model was assessed using the area under the receiver operating characteristic curve (AUC-ROC), and calibration was examined to ensure reliability. Kaplan-Meier analyses were performed to visualize survival distributions across key subgroups.Results: This study included 1575 patients, of whom 372 and 1203 had VaM and VuM, respectively. The median patient age was 67 years, and the median tumor size was 2.4 cm. The 5-year survival rate of patients with VuM (45.4%) was significantly higher than that of patients with VaM (15.2%) (P < 0.001).Conclusions: This study highlights the aggressive nature of rare GU melanomas and the importance of surgical intervention and caution in the use of chemotherapy and radiotherapy.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2540747"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12452445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145080393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Toward comprehensive palliative care training: addressing gender and training stage differences in medical education. 迈向全面的姑息治疗培训：解决医学教育中的性别和培训阶段差异。

IF 2.1

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-10-03 DOI: 10.1080/20565623.2025.2553474

Alia Alawneh, Sakhr Alshwayyat, Ayman Shatnawi, Abdalwahab Alenezy, Karam Maraqa

{"title":"Toward comprehensive palliative care training: addressing gender and training stage differences in medical education.","authors":"Alia Alawneh, Sakhr Alshwayyat, Ayman Shatnawi, Abdalwahab Alenezy, Karam Maraqa","doi":"10.1080/20565623.2025.2553474","DOIUrl":"10.1080/20565623.2025.2553474","url":null,"abstract":"Background: Palliative care (PC) education is globally recommended; however, many regions lack sufficient training. This study aimed to evaluate medical students' confidence in PC and pain management and to compare confidence levels according to year of training and both male and female genders.Methods: This observational study was conducted at a medical school in northern Jordan. A convenience sample of medical students were asked to fill a survey comprising the Self-Efficacy in Palliative Care Scale (SEPC) and Thanatophobia Scale (TS).Results: In total, 289 students were enrolled in this study. In their first year of clinical training, 137 were female and 130 were students. In the SEPC, discussing the patient's death with the patient was the domain in which the students were least confident. Confidence in working on a multi-professional PC team was recognized as the highest skill area among the participants. Confidence in students' ability to assess patients' pain needs was identified as the most confident skill, whereas their ability to prescribe appropriate pain control medications was the lowest. There was a significant difference in TS between the female and male medical students.Conclusion: An integrated pain and PC curriculum in medical schools is essential to help students achieve confidence in pain management and palliative care.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2553474"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498538/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation of salivary proteomic biomarkers for early detection of oral cancer in the Egyptian population. 验证唾液蛋白质组学生物标志物早期检测口腔癌在埃及人口。

IF 2.4

Future Science OA Pub Date : 2025-12-01 Epub Date: 2024-12-06 DOI: 10.1080/20565623.2024.2432222

Dalia Ghalwash, Ahmed Ammar, Asmaa Abou-Bakr, Al-Hassan Diab, Ayman El-Gawish

{"title":"Validation of salivary proteomic biomarkers for early detection of oral cancer in the Egyptian population.","authors":"Dalia Ghalwash, Ahmed Ammar, Asmaa Abou-Bakr, Al-Hassan Diab, Ayman El-Gawish","doi":"10.1080/20565623.2024.2432222","DOIUrl":"10.1080/20565623.2024.2432222","url":null,"abstract":"Purpose: The present study evaluated the sensitivity and specificity of important proteomic salivary biomarkers; IL-6, IL-8, and sCD44 in the early detection of oral cancer, and any possible associations with risk factors of oral cancer in an Egyptian population.Methods: The present investigation was conducted on 100 individuals; 25 healthy controls, 25 patients having oral potentially malignant disorders (OPMDs) with dysplasia; 25 patients having OPMDs without dysplasia, and 25 oral cancer patients. Demographic data modified gingival index, oral hygiene level, and salivary levels of the biomarkers were assessed.Results: Salivary levels of IL-6, IL-8, and sCD44 progressively increased with increased disease severity. Salivary IL-8 and IL-6 levels possess a discriminating potential from normal tissue through different degrees of dysplasia to oral cancer, sCD44 levels had a discriminating power between normal and dysplastic tissues with high sensitivity and specificity. A positive correlation was found between the three biomarkers and the grade of oral squamous cell carcinoma (OSCC) and with different risk factors.Conclusion: This is the first study that evaluated multiple salivary proteomic biomarkers in the Egyptian population, and the results validate the ability of IL-6, IL-8, and sCD44 to be used as sensitive diagnostic and prognostic biomarkers for screening and early detection of oral cancer.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2432222"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142784617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The value of peripheral blood inflammation markers in risk assessment and prediction of lung cancer. 外周血炎症标志物在肺癌风险评估和预测中的价值。

IF 2.4

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-03-13 DOI: 10.1080/20565623.2025.2476870

Yong Xie, Qi Yu, Yujun Zhu, Wen Wu, Rong Xiao, Naiqun Wang, Liangbo Zhu, Ping Li, Tao Chen

{"title":"The value of peripheral blood inflammation markers in risk assessment and prediction of lung cancer.","authors":"Yong Xie, Qi Yu, Yujun Zhu, Wen Wu, Rong Xiao, Naiqun Wang, Liangbo Zhu, Ping Li, Tao Chen","doi":"10.1080/20565623.2025.2476870","DOIUrl":"10.1080/20565623.2025.2476870","url":null,"abstract":"Background: Lung cancer has high mortality rates globally, with inflammatory processes playing a pivotal role in NSCLC progression. Peripheral blood inflammation markers offer promise for NSCLC risk assessment and prediction.Methods: A retrospective case-control study included 50 NSCLC patients and 50 healthy individuals admitted for routine health examinations as controls. Clinical data were collected, and blood routine tests were conducted on the first day of admission. We compared white blood cells, neutrophils, lymphocytes, monocytes, platelets, NLR (Neutrophil-to-Lymphocyte Ratio), LMR (Lymphocyte-to-Monocyte Ratio), PLR (Platelet-to-Lymphocyte Ratio), dNLR (derived NLR), and SII (Systemic Immune-inflammation Index). Logistic regression and ROC curve analysis were used to evaluate their predictive value.Results: NLR was significantly higher in NSCLC patients than in healthy controls, and elevated NLR was strongly associated with increased odds of having NSCLC. Neutrophil, lymphocyte, and monocyte counts also contributed to the odds of having NSCLC. NLR showed the highest predictive value with an AUC of 0.911, indicating excellent accuracy.increased odds of having NSCLC.Conclusions: Our findings suggest that peripheral blood inflammation markers, particularly the NLR, may have potential utility in risk assessment and prediction for NSCLC. These markers warrant further investigation to explore their potential role in early diagnosis and monitoring of NSCLC.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2476870"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11916372/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oxidative markers and SOD variant: predictors of autism severity and susceptibility. 氧化标记物和SOD变异：自闭症严重程度和易感性的预测因子。

IF 2.4

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-03-31 DOI: 10.1080/20565623.2025.2483628

Abdullah Abubaker Shareef, Azad Hasan Kheder, Niaz Albarzinji, Karim Jalal Karim, Shukur Wasman Smail, Abuabkr Abdalla Mahmood, Kawa Amin

{"title":"Oxidative markers and SOD variant: predictors of autism severity and susceptibility.","authors":"Abdullah Abubaker Shareef, Azad Hasan Kheder, Niaz Albarzinji, Karim Jalal Karim, Shukur Wasman Smail, Abuabkr Abdalla Mahmood, Kawa Amin","doi":"10.1080/20565623.2025.2483628","DOIUrl":"10.1080/20565623.2025.2483628","url":null,"abstract":"Background: This study examines the relationship between oxidative stress, anti-oxidative markers, and the Ala16Val SOD2 polymorphism in children with autism spectrum disorder (ASD) to better understand ASD severity and susceptibility.Material and methods: The study included 80 children (40 with ASD and 40 controls) from Erbil City, Iraq.Results: Serum antioxidant markers, such as superoxide dismutase (SOD) and glutathione peroxidase (GPX), were significantly lower in ASD patients compared to controls (P = 0.036 and P < 0.001, respectively), while markers of oxidative damage, including malondialdehyde (MDA), nitric oxide (NO), and cytochrome C, were significantly elevated (P < 0.001). Regression analysis revealed reduced SOD and GPX activities were strongly associated with increased autism severity, as measured by the childhood autism rating scale (CARS), while elevated NO and cytochrome C levels also correlated positively with higher CARS scores. Although the Ala16Val SOD polymorphism was not significantly associated with ASD risk, logistic regression showed no connection between SOD genotypes and serum SOD levels.Conclusion: These findings suggest oxidative stress and impaired antioxidant defense play critical roles in ASD severity.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2483628"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11959902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel compounds of Taiwanese green propolis induce apoptosis of human glioblastoma cells by daylight photodynamic action. 台湾绿色蜂胶的新化合物通过日光光动力作用诱导人胶质母细胞瘤细胞凋亡。

IF 2.4

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-02-10 DOI: 10.1080/20565623.2025.2464491

Daniel Tzu-Hsuan Chen, Shin-Yi Huang, Ta-Chun Liu, Yao-Kuan Chen

{"title":"Novel compounds of Taiwanese green propolis induce apoptosis of human glioblastoma cells by daylight photodynamic action.","authors":"Daniel Tzu-Hsuan Chen, Shin-Yi Huang, Ta-Chun Liu, Yao-Kuan Chen","doi":"10.1080/20565623.2025.2464491","DOIUrl":"10.1080/20565623.2025.2464491","url":null,"abstract":"Background: Glioblastoma, an aggressive brain cancer, has limited treatment options and poor prognosis. Taiwanese green propolis, known for its tumor-inhibitory properties, shows promise when combined with photodynamic therapy (PDT), a targeted, low-toxicity treatment. This study investigated a novel Taiwanese green propolis-based compound for inducing apoptosis in glioblastoma cells and its synergistic potential with daylight PDT.Methods: Ethanol extracts of green propolis, wheatgrass, and mulberry leaves were combined and analyzed using High-Performance Liquid Chromatography (HPLC). Apoptosis induction in U87 glioblastoma cells was assessed via the MTT assay following treatment with the compound alone and in combination with daylight PDT at 570 nm.Results: We identified Artepillin C as the main active component in the compound by HPLC, which significantly induced apoptosis in glioblastoma cells. Combined with daylight PDT, it demonstrated enhanced efficacy, with cell viability reduced from 95.2% at 0.25 µL to 11.3% at 8 µL of the compound extract. The EC50 decreased, indicating greater apoptotic activity compared to the extract alone.Conclusion: This study provides the first in vitro evidence of synergistic anti-tumor effects of a Taiwanese green propolis-based compound daylight PDT (GPDT), highlighting a promising novel therapeutic approach that warrants further clinical investigation.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2464491"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The potential of Abrus precatorius leaves in arthritis alleviation computational approaches through lC-MS analysis. 通过lC-MS分析，Abrus precatorius叶子在关节炎缓解计算方法中的潜力。

IF 2.4

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-03-25 DOI: 10.1080/20565623.2025.2483131

Sukanya Vijayan, Thirumal Margesan

引用次数: 0

Knowledge and awareness of breast cancer signs and symptoms among Jordanian women. 约旦妇女对乳腺癌体征和症状的了解和认识。

IF 2.4

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-05-28 DOI: 10.1080/20565623.2025.2510871

Amjad Z Alrosan, Tahani Alwidyan, Ghaith B Heilat, Aseel O Rataan, Saba Madae'en, Khaled Alrosan, Farah S Awwad, Tasneem Ali

{"title":"Knowledge and awareness of breast cancer signs and symptoms among Jordanian women.","authors":"Amjad Z Alrosan, Tahani Alwidyan, Ghaith B Heilat, Aseel O Rataan, Saba Madae'en, Khaled Alrosan, Farah S Awwad, Tasneem Ali","doi":"10.1080/20565623.2025.2510871","DOIUrl":"10.1080/20565623.2025.2510871","url":null,"abstract":"Background: Breast cancer (BC) remains the most common cancer among women worldwide. Early detection plays a vital role in reducing morbidity and mortality. This study aimed to assess Jordanian women's awareness of BC signs and symptoms to support timely recognition and intervention.Research design and methods: A nationwide cross-sectional study was conducted involving 381 Jordanian women from the general community. Participants completed a self-administered questionnaire assessing their knowledge of BC signs and symptoms using a three-point Likert scale (\"Yes,\" \"Unsure,\" \"No\"). Demographic variables were analyzed for association with knowledge levels using Pearson's Chi-square or Fisher's Exact Test.Results: 80.3% of participants demonstrated good awareness of BC signs and symptoms. Significant associations were found between knowledge levels and marital status (p = 0.000), age (p = 0.033), having children (p = 0.000), number of children (p = 0.003), education specialty (p = 0.000), and working area (p = 0.005).Conclusions: Most participants demonstrated a strong awareness of BC signs and symptoms. However, educational interventions are needed to target knowledge gaps, particularly among unmarried women.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2510871"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12123941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0