Future Science OA最新文献

Evaluation of the efficacy of triazavirin versus oseltamivir in management of COVID-19. 评估三唑韦林与奥司他韦在治疗 COVID-19 中的疗效。

IF 2.4

Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-11-14 DOI: 10.1080/20565623.2024.2418798

Sara Samir Mohamed Elmenshawy, Mohamed Farouk Ahmed Abdelsalam, Tarek Refaat El Nagdy, Mohamed Abdel Salam Elgohary, Nagwa Ali Sabri, Amal El-Kholy

引用次数: 0

Green synthesized Zingiber officinale-ZnO nanoparticles: anticancer efficacy against 3D breast cancer model. 绿色合成的银杏叶-氧化锌纳米粒子：对三维乳腺癌模型的抗癌功效

IF 2.4

Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-11-14 DOI: 10.1080/20565623.2024.2419806

Ruqaya Alhaddad, Bassam M Abualsoud, Ibrahim Al-Deeb, Hamdi Nsairat

引用次数: 0

The United Nations' ambitious roadmap against tuberculosis: opportunities, challenges and the imperative of equity. 联合国防治结核病的宏伟路线图：机遇、挑战和公平的必要性。

IF 2.4

Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-11-14 DOI: 10.1080/20565623.2024.2418787

Bashar Haruna Gulumbe, Abdulrakib Abdulrahim, Mohammed Bashar Danlami

引用次数: 0

Effect of house dust mite sublingual immunotherapy in patients with adult atopic dermatitis with rhinitis. 屋尘螨舌下免疫疗法对伴有鼻炎的成人特应性皮炎患者的疗效。

IF 2.4

Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-11-14 DOI: 10.1080/20565623.2024.2419779

Mayuko Mizuno, Shinya Imamura, Ai Yoshioka, Ken Washio, Yoshiko Oda, Hiroki Matsuhara, Katsuyo Ohashi-Doi, Atsushi Fukunaga

引用次数: 0

Challenging case of disseminated tuberculosis in an immunocompetent adult. 一个免疫功能正常的成年人感染播散性结核病的棘手病例。

IF 2.4

Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-11-14 DOI: 10.1080/20565623.2024.2419392

Narjes Abid, Ella Nemsi, Siwar Sbaihi, Rahma Ayadi, Manel Loukil, Nada Gader, Khaoula Hemissi, Hedia Ghrairi

{"title":"Challenging case of disseminated tuberculosis in an immunocompetent adult.","authors":"Narjes Abid, Ella Nemsi, Siwar Sbaihi, Rahma Ayadi, Manel Loukil, Nada Gader, Khaoula Hemissi, Hedia Ghrairi","doi":"10.1080/20565623.2024.2419392","DOIUrl":"10.1080/20565623.2024.2419392","url":null,"abstract":"Disseminated tuberculosis (TB) is a TB infection involving two or more noncontiguous sites. It is a challenging medical care due to its misleading presentation. Although it is associated with immunodepression, rare cases have been described in immunocompetent patients.We report the case of a 27-year-old immunocompetent man who presented with an altered general condition and dyspnea. Chest computed tomography (CT) revealed pulmonary masses and mediastinal lymphadenopathy. Sputum smear microscopy for acid-fast bacilli was negative. Scannoguided transparietal lung biopsy was performed twice with inflammatory tissue in histological study. A surgical lung biopsy was then made. The histopathology report confirmed TB involving lung, pleura and lymph nodes. A few days after antituberculosis therapy was started, the patient developed psychomotor slowing related to quadriportal hydrocephalus. He benefited from ventriculoperitoneal bypass. Polymerase chain reaction for detection of Mycobacterium TB was positive in cerebrospinal fluid.In conclusion: The diagnosis of disseminated TB is challenging owing to its non-specific clinical and radiological presentation and the frequent negativity of biological fluids for tubercle bacilli. Molecular biology should always be considered in front of lingering symptoms, particularly in endemic areas, given their speed and sensitivity, thus avoiding invasive diagnostic procedures, as was the case with our patient.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"10 1","pages":"2419392"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sociodemographic factors are related to hair sample collection in economically marginalized families. 社会人口因素与经济边缘化家庭的头发样本采集有关。

IF 2.4

Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-11-14 DOI: 10.1080/20565623.2024.2420561

Jiying Ling, Dalton Goodwin, Charles Given

{"title":"Sociodemographic factors are related to hair sample collection in economically marginalized families.","authors":"Jiying Ling, Dalton Goodwin, Charles Given","doi":"10.1080/20565623.2024.2420561","DOIUrl":"10.1080/20565623.2024.2420561","url":null,"abstract":"Aim: Limited research has explored factors influencing participants' decisions to consent to and complete hair sample collection. This study examined the relationships of sociodemographics, perceived stress and coping with hair sample collection among children aged 3-5 years and parents.Research design & methods: Data were analyzed from 188 parent-child dyads. Among these, 78% of parents provided consent to hair sample collection. Hair samples were collected from 81% children and 68% parents.Results: Parents who provided consent reported higher levels of stress and used more avoidant coping strategies compared with those who did not. Parents who provided a hair sample engaged in less problem-focused coping. Children who were girls, non-Hispanic and White had higher odds of completing hair sample collection. Additionally, children were more likely to complete hair sample collection if their parents were married, employed full-time, or had an annual family income of ≥$20,000. Pregnant women and full-time employed parents also had higher odds of completing hair sample collection.Conclusion: The study identified important sociodemographic factors that may influence hair sample collection in research. To improve participation, tailored approaches such as at-home self-collection, sensitive hair cutting approaches to maintain participants' hair style, and addressing participants' unique barriers are recommended.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"10 1","pages":"2420561"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CD4+ T-cell transcription factors predict phenoconversion in idiopathic rapid eye movement sleep behavior disorder. CD4+ T细胞转录因子可预测特发性快速眼动睡眠行为障碍的表型转换。

IF 2.4

Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-11-14 DOI: 10.1080/20565623.2024.2418821

Monica Pinoli, Michele Terzaghi, Franca Marino, Cristoforo Comi, Maurizio Versino, Marco Cosentino

{"title":"CD4+ T-cell transcription factors predict phenoconversion in idiopathic rapid eye movement sleep behavior disorder.","authors":"Monica Pinoli, Michele Terzaghi, Franca Marino, Cristoforo Comi, Maurizio Versino, Marco Cosentino","doi":"10.1080/20565623.2024.2418821","DOIUrl":"10.1080/20565623.2024.2418821","url":null,"abstract":"Aim: Early biomarkers of phenoconversion to neurodegeneration are crucial to identify individuals at high risk. In patients with idiopathic REM sleep behavior disorder (iRBD), the strongest risk factor for neurodegeneration, CD4+ T cells exhibit a peculiar transcription factor pattern.Objective: To assess transcription factor mRNA levels in CD4+ T cells as predictive biomarkers of phenoconversion in iRBD patients.Methods: iRBD patients were followed prospectively. ROC curve analysis and Kaplan-Meier curves were used to assess the discrimination between converters and non-converters.Results: CD4+ T cells from converters had higher STAT1, and lower GATA3 and FOXP3 mRNA levels. Hazard ratio was 58.3 (95% CI: 6.2-547.1) for higher STAT1, 101.2 (95% CI: 16.8-609.4) for lower GATA3 and 15.7 (2.7-91.4) for lower FOXP3.Conclusion: STAT1, GATA3 and FOXP3 mRNA levels in CD4+ T cells are promising predictive biomarkers of phenoconversion in iRBD patients.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"10 1","pages":"2418821"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Local recurrences for mixed germ cell tumors without scrotal violation, is metastatic disease around the corner? A case report. 无阴囊侵犯的混合生殖细胞瘤局部复发，转移性疾病指日可待？病例报告。

IF 2.4

Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-11-14 DOI: 10.1080/20565623.2024.2420543

Georges Abi Tayeh, Constance Michel, Xavier Durand

引用次数: 0

Unveiling the crisis: cocaine abuse's deadly connection to heart disease in Pakistan. 揭开危机的面纱：巴基斯坦可卡因滥用与心脏病的致命联系。

IF 2.4

Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-11-14 DOI: 10.1080/20565623.2024.2419331

Jawad Ghias Shaikh, Ahmed Asad Raza, Muhammad Abdul Qadeer

引用次数: 0

Examining symptom and quality of life in polycystic ovarian syndrome: a web-based cross-sectional study. 考察多囊卵巢综合征的症状和生活质量：一项基于网络的横断面研究。

IF 2.4

Future Science OA Pub Date : 2024-12-01 Epub Date: 2024-11-19 DOI: 10.1080/20565623.2024.2430878

Rukaiah Fatma Begum, Chitra Vellapandian, Sumithra Mohan

{"title":"Examining symptom and quality of life in polycystic ovarian syndrome: a web-based cross-sectional study.","authors":"Rukaiah Fatma Begum, Chitra Vellapandian, Sumithra Mohan","doi":"10.1080/20565623.2024.2430878","DOIUrl":"https://doi.org/10.1080/20565623.2024.2430878","url":null,"abstract":"Background: Polycystic Ovarian Syndrome (PCOS) is a reproductive disorder that significantly impacts women's quality of life (QOL). Its unclear etiology, whether genetic or environmental, and the treatments associated with it have been widely studied globally.Research design and methods: This study assessed the QOL of 108 women with PCOS, examining both physical and mental symptoms. Participants completed the Short Form-12 (SF-12) questionnaire through a web-based survey to evaluate their QOL scores.Results: Common symptoms included menstrual irregularity (73.14%), hirsutism (65.7%), acne (62.03%), and obesity (22.22%). Complications such as diabetes mellitus (12.9%), hypertension (2.78%), infertility (1.85%), miscarriages (31.4%), hyperandrogenism (68.51%), and insulin resistance (28.7%) were reported. Patients with infertility had the lowest physical scores (PCS), while those working night shifts had the lowest mental scores (MCS).Conclusion: PCOS significantly affects QOL, with infertility contributing to the lowest physical scores and night shift work correlating with the lowest mental scores. These findings emphasize the need for integrated psychological and physical care, particularly for young working women with PCOS.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"10 1","pages":"2430878"},"PeriodicalIF":2.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0