Future Science OA最新文献_第10页

Comparison of bismuth and concomitant therapy for H. pylori eradication: a prospective, randomized clinical trial. 比较铋和伴随治疗根除幽门螺杆菌：一项前瞻性，随机临床试验。

IF 2.4

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-07-10 DOI: 10.1080/20565623.2025.2527539

A Oueslati, G Mohamed, S Bostani, K Boughoula, S Bizid, H Ben Abdallah, R Bouali, M N Abdelli

{"title":"Comparison of bismuth and concomitant therapy for H. pylori eradication: a prospective, randomized clinical trial.","authors":"A Oueslati, G Mohamed, S Bostani, K Boughoula, S Bizid, H Ben Abdallah, R Bouali, M N Abdelli","doi":"10.1080/20565623.2025.2527539","DOIUrl":"10.1080/20565623.2025.2527539","url":null,"abstract":"Background: In Tunisia, concomitant quadruple therapy (QTC) has been the standard first-line treatment for Helicobacter pylori (H. pylori) infection. However, increasing resistance to clarithromycin (28%) has raised concerns about its long-term efficacy. Bismuth-based quadruple therapy (QTB) offers an alternative, yet its higher cost and safety profile remain debated. This study aimed to compare the efficacy, safety, and cost of both regimens.Methods: We conducted a prospective, randomized, open-label study enrolling 200 patients naïve to any anti-HP treatment. Patients were randomized to either 10 days of bismuth therapy (QTB: potassium bismuth subcitrate, metronidazole, and tetracycline hydrochloride, omeprazole) or 14 days of concomitant quadruple therapy (QTC: amoxicillin, clarithromycin, metronidazole, esomeprazole). H. pylori eradication as defined by a negative urea breath test 4-6 weeks after treatment.Results: Among 200 patients, the intention-to-treat eradication rate was 82% for QTC and 87% for QTB (p = 0.29); per-protocol rates were 84.53% and 89.58%, respectively (p = 0.39). Compliance was high (97% in QTC vs 96% in QTB; p = 0.32). Adverse events were similar between groups (61.85% for QTB vs 69% for QTC; p = 0.29).Conclusion: Bismuth and concomitant quadruple therapies were comparable in terms of efficacy and safety but didn't achieve the accepted minimum eradication rate (90%).","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2527539"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12247181/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital pulmonary airway malformation type 2 associated with intralobar pulmonary sequestration in an adult patient: a case report. 2型先天性肺气道畸形伴肺叶内肺隔离1例。

IF 2.4

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-07-02 DOI: 10.1080/20565623.2025.2527473

Asma Knaz, Soumaya Boujneh, Bechir Ben Radhia, Marwa Krifa, Iteb BenLimem, Wafa Benzarti, Ahmed Abdelghani

引用次数: 0

The expression and prognostic predictive value of PD-L2 in patients undergoing radical gastric cancer surgery. PD-L2在胃癌根治性手术患者中的表达及预后预测价值

IF 2.4

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-07-02 DOI: 10.1080/20565623.2025.2526993

Xiuping Zhang, Maodong Fu, Zhiyong Li, Feng Shen, Huan Chen, Zhiming Wang, Jingmei Zheng

{"title":"The expression and prognostic predictive value of PD-L2 in patients undergoing radical gastric cancer surgery.","authors":"Xiuping Zhang, Maodong Fu, Zhiyong Li, Feng Shen, Huan Chen, Zhiming Wang, Jingmei Zheng","doi":"10.1080/20565623.2025.2526993","DOIUrl":"10.1080/20565623.2025.2526993","url":null,"abstract":"Background: The expression and prognostic predictive value of programmed death-ligand 2 (PD-L2) in patients undergoing radical gastric cancer (GC) surgery remains unclear.Methods: PD-L2 expression in tumor cells (TC) and tumor-infiltrating immune cells (TIIC) was evaluated by immunohistochemistry. Kaplan-Meier and Cox models were used to evaluate the association of PD-L2 with disease-free survival (DFS) and overall survival (OS).Results: This study included 299 patients and the average age was 63.76 ± 11.83 years, with 218 males (72.91%) and 81 females (27.09%). TC PD-L2 expression was significantly associated with poorer DFS (HR = 2.177, 95% CI 1.364-3.474, P = 0.001) and OS (HR = 1.943, 95% CI 1.191-3.169, P = 0.008). Multivariate analysis confirmed TC PD-L2 expression as an independent poor prognostic factor for DFS (HR = 2.121, 95% CI 1.325-3.393, P = 0.002) and OS (HR = 1.812, 95% CI 1.109-2.961, P = 0.018). PD-L2 in TIIC did not correlate with survival. Other poor prognostic factors included age ≥60, vascular invasion, advanced postoperative stage, and HER2 positivity.Conclusions: PD-L2 expression in TC is an independent prognostic biomarker in GC, linked to poorer DFS and OS, suggesting its potential for identifying high-risk patients for personalized therapies.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2526993"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233815/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144539947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Amniotic fluid MSCs for scaffold-free cartilage repair: spheroid fusion and chondrogenic microtissue development. 羊水间充质干细胞用于无支架软骨修复：球体融合和软骨微组织发育。

IF 2.4

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-06-11 DOI: 10.1080/20565623.2025.2476922

Carolina Coli Zuliani, Jéssica Bruna da Cunha, Victor Marchiori de Souza, Kleber Cursino de Andrade, Ângela Maria Moraes, Ibsen Bellini Coimbra

{"title":"Amniotic fluid MSCs for scaffold-free cartilage repair: spheroid fusion and chondrogenic microtissue development.","authors":"Carolina Coli Zuliani, Jéssica Bruna da Cunha, Victor Marchiori de Souza, Kleber Cursino de Andrade, Ângela Maria Moraes, Ibsen Bellini Coimbra","doi":"10.1080/20565623.2025.2476922","DOIUrl":"10.1080/20565623.2025.2476922","url":null,"abstract":"Background: Articular cartilage injuries are challenging due to limited regenerative capacity, causing chronic pain and impaired mobility. Current treatments are often inadequate, necessitating novel cartilage repair approaches. This study investigates amniotic fluid-derived mesenchymal stromal cells (AF-MSC) as a promising cell source for tissue engineering.Research design and method: Cartilage-like microtissues were produced by differentiating AF-MSC into chondrocytes within a 3D culture system. Using a 3D-printed non-adhesive micromold, AF-MSC spheroids were formed and fused into larger microtissues. Spheroids were characterized for morphology, viability, and extracellular matrix (ECM) production. The mechanical properties of resulting microtissues were compared to native cartilage and agarose hydrogel.Results: AF-MSC proved a viable, scalable cell source for cartilage microtissues. Spheroid fusion created structures with mechanical properties and ECM components resembling native cartilage.Conclusions: AF-MSCs differentiated into chondrocytes when stimulated with TGF-β3 in a 3D micromolded culture, forming uniform, viable spheroids with robust ECM production and mechanical properties. These spheroids fused into neocartilage microtissue, showing potential for regenerative medicine, especially osteoarthritis treatment and drug testing. Further research should optimize conditions and evaluate long-term biomechanical performance.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2476922"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12160606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge, attitudes, and barriers regarding health promotion of ovarian cancer among community pharmacists in Jordan. 约旦社区药剂师对卵巢癌健康促进的知识、态度和障碍

IF 2.1

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-07-31 DOI: 10.1080/20565623.2025.2536386

Khaled Alrosan, Mohanad Odeh, Tahani Alwidyan, Amjad Z Alrosan, Saba Madae'en

{"title":"Knowledge, attitudes, and barriers regarding health promotion of ovarian cancer among community pharmacists in Jordan.","authors":"Khaled Alrosan, Mohanad Odeh, Tahani Alwidyan, Amjad Z Alrosan, Saba Madae'en","doi":"10.1080/20565623.2025.2536386","DOIUrl":"10.1080/20565623.2025.2536386","url":null,"abstract":"BackgroundOvarian cancer is the most lethal gynecological cancer in women, which is characterized by nonspecific symptoms that delays its diagnosis until advanced stages, thus it has been called the silent killer disease. Since community pharmacists are easily accessible healthcare providers, and because of their roles in health promotion activities and disease prevention services; this study was conducted to better understand their knowledge, attitudes, and challenges toward ovarian cancer health promotion.Methods: An internet-based self-administrated questionnaire was distributed to community pharmacists in Jordan (n = 194) with a response rate of 53.9% through an online platform.Results: About 75.2% of the community pharmacists had insufficient knowledge score of ovarian cancer and 58.2% had a higher-positive attitude. There was a significant association between the community pharmacist knowledge score and the work status or the education level (p < 0.05). The perceived lack of pharmacist' s knowledge and the absence of a private area in pharmacies for confidential conversations represent the major barriers (72.1% and 69.6%, respectively).Conclusion: Despite limited knowledge about the symptoms and risk factors of ovarian cancer, as well as barriers hindering the full realization of community pharmacists' roles, they demonstrated a positive attitude toward educating patients about ovarian cancer health.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2536386"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12320827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Causal effect of potential risk factors on obstructive sleep apnea: a Mendelian randomization study. 阻塞性睡眠呼吸暂停的潜在危险因素的因果影响：一项孟德尔随机研究。

IF 2.1

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-08-02 DOI: 10.1080/20565623.2025.2541530

Jia Chen, Weixing Liu, Pei Li, Yue Liu, Zhiyuan Wang, Hui Liu, Jin Ye

{"title":"Causal effect of potential risk factors on obstructive sleep apnea: a Mendelian randomization study.","authors":"Jia Chen, Weixing Liu, Pei Li, Yue Liu, Zhiyuan Wang, Hui Liu, Jin Ye","doi":"10.1080/20565623.2025.2541530","DOIUrl":"10.1080/20565623.2025.2541530","url":null,"abstract":"Introduction: Observational epidemiological studies have revealed that multiple risk factors may be associated with the risk of obstructive sleep apnea (OSA). However, the causal relationship between them remains largely unknown. We aimed to investigate the causal relationship between potential risk factors and OSA risk.Methods: A two-sample Mendelian randomization approach was used to evaluate the causal association of 42 risk factors with OSA risk. Summary data on OSA were obtained from a recently published genome-wide association study including 16,761 patients with OSA.Results: Suggestive associations with increased risk were observed for body mass index (OR = 2.19, 95% CI 1.99-2.42, P < 0.01), childhood body mass index (OR = 1.46, 95% CI 1.15-1.83, P < 0.01), overweight (OR = 1.43, 95% CI 1.17-1.74, P < 0.01), smoking initiation (OR = 1.27, 95% CI 1.09-1.49, P < 0.01), gastroesophageal reflux disease (OR = 1.60, 95% CI 1.40-1.82, P < 0.01), and depression (OR = 1.28, 95% CI 1.06-1.53, P = 0.01). Age at first birth (OR = 0.88, 95% CI 0.82-0.94, P < 0.01) and education (OR = 0.76, 95% CI 0.66-0.87, P < 0.01) were significantly associated with decreased risk of OSA.Conclusions: We found a causal effect for several potential risk factors on OSA risk, including obesity, smoking, education, age at first birth, gastroesophageal reflux disease, and depression.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2541530"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12320811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144768606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Plasma metabolic landscape unveils key regulators of leukemia subtype progression. 血浆代谢景观揭示白血病亚型进展的关键调节因子。

IF 2.1

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-09-01 DOI: 10.1080/20565623.2025.2527015

Cong Liang, Jia-Yu Lin, Liu-Hua Liao, Shi-Yao Song, Jia-Tong Dai, Jia-Jie Chen, Zhi-Yong Ke, Hong-Man Xue

{"title":"Plasma metabolic landscape unveils key regulators of leukemia subtype progression.","authors":"Cong Liang, Jia-Yu Lin, Liu-Hua Liao, Shi-Yao Song, Jia-Tong Dai, Jia-Jie Chen, Zhi-Yong Ke, Hong-Man Xue","doi":"10.1080/20565623.2025.2527015","DOIUrl":"10.1080/20565623.2025.2527015","url":null,"abstract":"Background: Leukemia is driven by metabolic reprogramming, yet the specific causal roles of plasma metabolites in distinct leukemia subtypes remain unclear.Methods: This study employed Mendelian randomization (MR) to explore potential causal links between 690 plasma metabolites (and 143 metabolite ratios) and four leukemia subtypes: ALL, AML, CLL, and CML. Genetic variants from genome-wide association studies served as instrumental variables. Multiple MR approaches, including IVW, MR-Egger, and Weighted Median, along with sensitivity analyses, were applied to ensure robust results.Results: Our findings revealed subtype-specific metabolite associations. In ALL, metabolites such as 3-Hydroxyisobutyrate and γ-Glutamylglutamate showed positive associations, while Phosphocholine and Ceramide showed negative associations. AML was positively linked to GlcNAc/GalNAc and negatively to 1-Methylnicotinamide. CLL showed positive associations with Butyrate/Isobutyrate and Androstenediol Monosulfate, and negative ones with Docosatrienoate and α-Tocopherol to Sulfate ratio. CML exhibited negative associations with Cysteine-Glutathione disulfide and Piperine.Conclusion: Our MR study provides a comprehensive evaluation of the metabolomic landscape of leukemia, identifying subtype-specific causal associations involving pathways such as energy metabolism, amino acid metabolism, lipid signaling, and redox homeostasis. These findings offer insights into potential plasma biomarkers and therapeutic targets, revealing distinct metabolic vulnerabilities that warrant further investigation for precision treatment strategies across leukemia subtypes.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2527015"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12407637/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144950447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation of the Kazakh-language version of the 8-item Morisky Medication Adherence Scale in patients with arterial hypertension. 8项Morisky药物依从性量表哈萨克语版在高血压患者中的有效性验证。

IF 2.1

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-10-10 DOI: 10.1080/20565623.2025.2569291

Gulnaz Nuskabayeva, Kanatzhan Kemelbekov, Dilbar Aidarbekova, Yerbolat Saruarov, Nursultan Nurdinov, Kumissay Babayeva, Ugilzhan Tatykayeva, Elmira Iskandirova, Dinara Nemetova, Philip Morisky, Ainash Oshibayeva, Karlygash Sadykova

{"title":"Validation of the Kazakh-language version of the 8-item Morisky Medication Adherence Scale in patients with arterial hypertension.","authors":"Gulnaz Nuskabayeva, Kanatzhan Kemelbekov, Dilbar Aidarbekova, Yerbolat Saruarov, Nursultan Nurdinov, Kumissay Babayeva, Ugilzhan Tatykayeva, Elmira Iskandirova, Dinara Nemetova, Philip Morisky, Ainash Oshibayeva, Karlygash Sadykova","doi":"10.1080/20565623.2025.2569291","DOIUrl":"https://doi.org/10.1080/20565623.2025.2569291","url":null,"abstract":"Background: The effectiveness of pharmacological therapies relies not only on the intrinsic efficacy of medicines, but also medication adherence, the extent to which patients follow their prescribed regimens. Patients with chronic conditions, such as hypertension, are at an increased risk of exhibiting poor medication adherence. Therefore, identifying patients with poor medication adherence is an important aspect of treatment success.Research design and methods: The present study aims to translate and adapt the Morisky Medication Adherence Scale (MMAS-8), a self-reporting questionnaire to assess patients' adherence to prescribed therapy.Results: The study validated the translated questionnaire and assessed its psychometric properties among a cohort of 400 patients with arterial hypertension in Turkistan region in southern Kazakhstan. The findings of the present study show that the Kazakh version of the MMAS-8 possesses high validity, reliability, and internal consistency, thereby confirming its appropriateness as a reliable tool for assessing medication adherence among patients with arterial hypertension in Kazakhstan.Conclusion: The psychometric properties of the Kazakh adaptation were comparable to those of the original English version and other validated non- English versions of the MMAS-8.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2569291"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145274346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case report: lichen planus in a patient with ulcerative colitis receiving sulfasalazine: a drug effect or a disease manifestation? 病例报告：溃疡性结肠炎患者接受柳氮磺胺吡啶治疗后出现扁平苔藓：是药物作用还是疾病表现？

IF 2.4

Future Science OA Pub Date : 2025-12-01 Epub Date: 2024-12-05 DOI: 10.1080/20565623.2024.2432240

Ahmed Mohamed Nefzi, Haythem Yacoub, Asmahane Souissi, Hajer Hassine, Dhouha Cherif, Habiba Debbabi, Héla Kchir, Nadia Maamouri

引用次数: 0

Biodistribution and persistence of human umbilical cord-derived mesenchymal stem cells in NCG mice: a comparative study. 人脐带间充质干细胞在NCG小鼠体内的生物分布和持久性：一项比较研究。

IF 2.4

Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-03-04 DOI: 10.1080/20565623.2025.2471723

Guangyang Liu, Herui Wang, Xin Li, Yi Mi, Chenliang Zhang, Yaoyao Chen, Li Miao, Haomiao Long, Jun He, Qinggang Ge, Yongjun Liu

{"title":"Biodistribution and persistence of human umbilical cord-derived mesenchymal stem cells in NCG mice: a comparative study.","authors":"Guangyang Liu, Herui Wang, Xin Li, Yi Mi, Chenliang Zhang, Yaoyao Chen, Li Miao, Haomiao Long, Jun He, Qinggang Ge, Yongjun Liu","doi":"10.1080/20565623.2025.2471723","DOIUrl":"10.1080/20565623.2025.2471723","url":null,"abstract":"Introduction: This study aims to investigate the biodistribution and persistence of human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) in NCG mice post-intravenous injection, utilizing 89Zr-PET/CT, bioluminescence imaging, multiplex immunohistochemistry (mIHC), and quantitative polymerase chain reaction (qPCR).Methods: hUC-MSCs were labeled with 89Zr-oxine (89Zr-MSCs) or transduced with luciferase gene (Luc-MSCs). Real-time tracking of 89Zr-MSCs lasted for 14-days followed by mIHC staining of hCD73. Real-time tracking of Luc-MSCs lasted for 7-days, followed by mIHC staining of hCD73 and human Alu-based qPCR. All methods adhered to ICH and other regulatory guidelines for development of cell-based drugs.Results: A biodistribution and persistence pattern was observed in the order of lung > liver > kidney > >spleen, although discrepancies were noted for the liver and kidney.Conclusion: Each method exhibited strengths and weaknesses: 89Zr-PET/CT enabled long-term tracking but encountered issues with 89Zr shedding and dead cells; bioluminescence provided specific detection but was hampered by a rapid decline in signal; mIHC identified cells but relied on antigen abundance; qPCR detected minimal cell quantities but was unable to differentiate between live and dead cells. These limitations may obscure the true fate of cells in vivo, highlighting the need for more accurate and reliable assessment techniques.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2471723"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0