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A promising RNA nanotechnology in clinical therapeutics: a future perspective narrative review. RNA纳米技术在临床治疗中的应用前景:未来展望。
IF 2.5
Future Science OA Pub Date : 2023-09-01 DOI: 10.2144/fsoa-2023-0067
Mahmoud M Tolba, Abdul Jabbar, Sadia Afzal, Mohammed Mahmoud, Farheen Zulfiqar, Ingy El-Soudany, Salma Samir, Al-Hassan Soliman Wadan, Takwa E Ellakwa, Doha El-Sayed Ellakwa
{"title":"A promising RNA nanotechnology in clinical therapeutics: a future perspective narrative review.","authors":"Mahmoud M Tolba,&nbsp;Abdul Jabbar,&nbsp;Sadia Afzal,&nbsp;Mohammed Mahmoud,&nbsp;Farheen Zulfiqar,&nbsp;Ingy El-Soudany,&nbsp;Salma Samir,&nbsp;Al-Hassan Soliman Wadan,&nbsp;Takwa E Ellakwa,&nbsp;Doha El-Sayed Ellakwa","doi":"10.2144/fsoa-2023-0067","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0067","url":null,"abstract":"<p><p>Nanotechnology is the use of materials that have unique nanoscale properties. In recent years, nanotechnologies have shown promising results for human health, especially in cancer treatment. The self-assembly characteristic of RNA is a powerful bottom-up approach to the design and creation of nanostructures through interdisciplinary biological, chemical and physical techniques. The use of RNA nanotechnology in therapeutics is about to be realized. This review discusses different kinds of nano-based drug delivery systems and their characteristic features.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 8","pages":"FSO883"},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10069741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A survey to explore the psychological and professional impact of change imposed by COVID-19. 一项旨在探讨COVID-19带来的变化对心理和职业影响的调查。
IF 2.5
Future Science OA Pub Date : 2023-09-01 DOI: 10.2144/fsoa-2023-0057
Mona Boudabbous, Nada Charfi, Héla Gdoura, Lassad Chtourou, Manel Moalla, Leila Mnif, Ali Amouri, Mohamed Maalej, Nabil Tahri
{"title":"A survey to explore the psychological and professional impact of change imposed by COVID-19.","authors":"Mona Boudabbous,&nbsp;Nada Charfi,&nbsp;Héla Gdoura,&nbsp;Lassad Chtourou,&nbsp;Manel Moalla,&nbsp;Leila Mnif,&nbsp;Ali Amouri,&nbsp;Mohamed Maalej,&nbsp;Nabil Tahri","doi":"10.2144/fsoa-2023-0057","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0057","url":null,"abstract":"<p><strong>Aim: </strong>Staff of a department underwent a change following the COVID-19 pandemic. The objective of this study was to assess the psychological and professional impact of this change.</p><p><strong>Materials & methods: </strong>This is cross-sectional study, including all department staff conducted from 15 July 2021 to 15 August 2021.</p><p><strong>Results: </strong>All the staff concerned (n = 36) participated. Only 9.37% declared that they understood the change. The main problem encountered by participants was poor communication (86.2%). More than 75% among participants had a demotivation and 54.5% had resisted. The main cause of resistance was quality of organization (42.4%).</p><p><strong>Conclusion: </strong>Our study illustrates the difficulties encountered by actors involved in organizational change and the high risk of their resistance.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 8","pages":"FSO879"},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10069744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Societal influence and psychological distress among Indonesian adults in Java on the early Omicron wave of COVID-19. 新冠肺炎早期奥密克戎疫情对爪哇印尼成年人的社会影响和心理困扰。
IF 2.4
Future Science OA Pub Date : 2023-08-29 eCollection Date: 2023-12-01 DOI: 10.2144/fsoa-2023-0104
Annette d'Arqom, Muh Akram, Nafesa Shafira Azzahranisa, Mhd Zamal Nasution, Endang Retno Surjaningrum, Junaidah Yusof
{"title":"Societal influence and psychological distress among Indonesian adults in Java on the early Omicron wave of COVID-19.","authors":"Annette d'Arqom, Muh Akram, Nafesa Shafira Azzahranisa, Mhd Zamal Nasution, Endang Retno Surjaningrum, Junaidah Yusof","doi":"10.2144/fsoa-2023-0104","DOIUrl":"10.2144/fsoa-2023-0104","url":null,"abstract":"<p><strong>Aim: </strong>Changes during the COVID-19 pandemic might create pressure on different people, thus this study aimed to measure respondents' psychological distress during the early phase of the Omicron wave in Java Island.</p><p><strong>Methods: </strong>A web-based survey on societal influence and COVID-19-related psychological distress was distributed through social media in November-December 2021, and received 396 responses.</p><p><strong>Results: </strong>This study showed that almost 50% of respondents faced psychological distress during the early phase of the Omicron variant, especially concerning hypervigilance and avoidance. Several sociodemographic factors might contribute to the incidence of psychological distress including comorbidity, age and education.</p><p><strong>Conclusion: </strong>Taken together, the incidence of COVID-19-related psychological distress was still found in the early phase of the Omicron variant, especially among young adults.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 10","pages":"FSO894"},"PeriodicalIF":2.4,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41105805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic performance of pretreatment systemic immune-inflammation index in women with epithelial ovarian cancer. 癌症患者术前全身免疫炎症指数对预后的影响。
IF 2.4
Future Science OA Pub Date : 2023-08-28 eCollection Date: 2023-12-01 DOI: 10.2144/fsoa-2023-0108
Kehinde S Okunade, Sarah O John-Olabode, Adaiah P Soibi-Harry, Austin C Okoro, Adebola A Adejimi, Iyabo Y Ademuyiwa, Benedetto Osunwusi, Hameed Adelabu, Omolola Salako
{"title":"Prognostic performance of pretreatment systemic immune-inflammation index in women with epithelial ovarian cancer.","authors":"Kehinde S Okunade, Sarah O John-Olabode, Adaiah P Soibi-Harry, Austin C Okoro, Adebola A Adejimi, Iyabo Y Ademuyiwa, Benedetto Osunwusi, Hameed Adelabu, Omolola Salako","doi":"10.2144/fsoa-2023-0108","DOIUrl":"10.2144/fsoa-2023-0108","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated the prognostic performance of the systemic immune-inflammation index (SII) in patients with epithelial ovarian cancer (EOC) in Lagos, Nigeria.</p><p><strong>Methods: </strong>We performed a secondary analysis of the data of 91 women who had treatment for EOC between 2009 and 2018. The associations between pretreatment SII and survivals were tested.</p><p><strong>Results: </strong>Pretreatment SII more than 610.2 was a significant independent predictor of reduced progression-free survival (HR = 2.68; 95% CI, 1.17 to 6.09) while SII greater than 649.0 was a significant independent predictor of reduced 3-year overall survival (HR = 2.01; 95% CI, 1.01 to 3.99).</p><p><strong>Conclusion: </strong>These findings suggest that high SII may be a potential prognostic indicator and useful marker for more intensive surveillance and design of personalized treatment in patients with EOC.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 10","pages":"FSO897"},"PeriodicalIF":2.4,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41117148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Data sets of human and mouse protein kinase inhibitors with curated activity data including covalent inhibitors. 具有精确活性数据的人和小鼠蛋白激酶抑制剂的数据集，包括共价抑制剂。
IF 2.5
Future Science OA Pub Date : 2023-08-16 eCollection Date: 2023-10-01 DOI: 10.2144/fsoa-2023-0088
Elena Xerxa, Jürgen Bajorath
{"title":"Data sets of human and mouse protein kinase inhibitors with curated activity data including covalent inhibitors.","authors":"Elena Xerxa,&nbsp;Jürgen Bajorath","doi":"10.2144/fsoa-2023-0088","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0088","url":null,"abstract":"<p><strong>Aim: </strong>Generation of high-quality data sets of protein kinase inhibitors (PKIs).</p><p><strong>Methodology: </strong>Publicly available PKIs with reliable activity data were curated. PKIs with very weak activity were classified as inactive. Analogue series and PKIs containing reactive groups (warheads) enabling covalent inhibition were systematically identified.</p><p><strong>Exemplary results & data: </strong>A total of 155,579 human and 3057 mouse PKIs were obtained. Human PKIs were active 440 kinases and included 13,949 covalent PKIs. The collection of qualifying PKIs and corresponding inactive compounds is made available as an open access deposition.</p><p><strong>Limitations & next steps: </strong>Potential limitations include activity data incompleteness and assay variance. The data set can be used to investigate PKIs with alternative modes of action and calibrate computational methods.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 9","pages":"FSO892"},"PeriodicalIF":2.5,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41149340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The prevalence, risk factors and lifestyle patterns of Jordanian females with premenstrual syndrome: a cross-sectional study. 约旦女性经前综合征的患病率、危险因素和生活方式：一项横断面研究。
IF 2.5
Future Science OA Pub Date : 2023-08-08 eCollection Date: 2023-10-01 DOI: 10.2144/fsoa-2023-0056
Mera A Ababneh, Malak Alkhalil, Abeer Rababa'h
{"title":"The prevalence, risk factors and lifestyle patterns of Jordanian females with premenstrual syndrome: a cross-sectional study.","authors":"Mera A Ababneh,&nbsp;Malak Alkhalil,&nbsp;Abeer Rababa'h","doi":"10.2144/fsoa-2023-0056","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0056","url":null,"abstract":"<p><strong>Aim: </strong>The study aims to assess factors associated with premenstrual syndrome (PMS) and the frequency of using painkillers to relieve premenstrual pain.</p><p><strong>Methods: </strong>This is a cross-sectional study of 1580 premenopausal women. An online self-administered questionnaire consists of sociodemographics, and the diagnostic criteria using the Arabic Premenstrual Syndrome Scale (A-PMS).</p><p><strong>Results: </strong>The prevalence of PMS among Jordanian females was 94%. Moreover, a significant correlation was found between several factors, including BMI, family history of PMS, smoking, and herbal tea consumption and the psychological, physical and behavioral symptoms of PMS. Furthermore, analgesic use for pain relief and food cravings were significantly associated with psychological, physical and behavioral PMS symptoms.</p><p><strong>Conclusion: </strong>PMS is highly prevalent and affects women in different life aspects.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 9","pages":"FSO889"},"PeriodicalIF":2.5,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41172968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare cause of spontaneous hemoperitoneum: intra-abdominal vein rupture. 自发性腹腔积血的罕见原因：腹腔内静脉破裂。
IF 2.5
Future Science OA Pub Date : 2023-08-08 eCollection Date: 2023-10-01 DOI: 10.2144/fsoa-2023-0029
Moufida Mahmoudi, Ghada Gharbi, Amal Khsiba, Amine Jallouli, Asma Ben Mohamed, Manel Yakoubi, Mouna Medhioub, Lamine Hamzaoui, Khaled Bouzaidi, Mohamed Mousadek Azouz
{"title":"A rare cause of spontaneous hemoperitoneum: intra-abdominal vein rupture.","authors":"Moufida Mahmoudi,&nbsp;Ghada Gharbi,&nbsp;Amal Khsiba,&nbsp;Amine Jallouli,&nbsp;Asma Ben Mohamed,&nbsp;Manel Yakoubi,&nbsp;Mouna Medhioub,&nbsp;Lamine Hamzaoui,&nbsp;Khaled Bouzaidi,&nbsp;Mohamed Mousadek Azouz","doi":"10.2144/fsoa-2023-0029","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0029","url":null,"abstract":"<p><strong>Aim: </strong>Ruptures of the intra-abdominal vein causing a spontaneous hemoperitoneum in cirrhotic patients is a rare condition. However, diagnosis must be considered early in cirrhotic patients with hematic ascites as a delayed diagnosis with hemodynamic instability is associated with a poor prognosis.</p><p><strong>Case report: </strong>We present the case of a 54-year-old cirrhotic patient who presented a spontaneous hemoperitoneum due to the rupture of the intra-abdominal vein that was diagnosed during exploratory laparoscopy.</p><p><strong>Conclusion: </strong>Early diagnosis and management of spontaneous hemoperitoneum due to the rupture of intra-abdominal vein helps improve its prognosis.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 9","pages":"FSO891"},"PeriodicalIF":2.5,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41122599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Migrasomes and tetraspanins in hepatocellular carcinoma: current status and future prospects. 肝细胞癌中的Migrasomes和tetraspanins：现状和未来展望。
IF 2.5
Future Science OA Pub Date : 2023-08-08 eCollection Date: 2023-10-01 DOI: 10.2144/fsoa-2023-0086
Zhongqi Zhang, Tianmiao Zhang, Rongcheng Zhang, Zhengbao Zhang, Shengkui Tan
{"title":"Migrasomes and tetraspanins in hepatocellular carcinoma: current status and future prospects.","authors":"Zhongqi Zhang,&nbsp;Tianmiao Zhang,&nbsp;Rongcheng Zhang,&nbsp;Zhengbao Zhang,&nbsp;Shengkui Tan","doi":"10.2144/fsoa-2023-0086","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0086","url":null,"abstract":"<p><p>In recent years, many studies have attempted to clarify the formation, structure and biological function of migrasomes, which are defined as specialized organelles formed by the tips and intersections of Retraction Fibrils during cell migration. It has confirmed that migrasomes were involved in various critical biological processes and diseases, and has became a new research hotspot. In this paper, we reviewed the formation and biological functions of migrasomes, explored the relationship between migrasomes, tetraspanins and hepatocellular carcinoma and discussed the potential applications of migrasomes in hepatocellular carcinoma.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 9","pages":"FSO890"},"PeriodicalIF":2.5,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41115853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology of bone tumors in Lebanon: a retrospective study from 2000 to 2022 at a tertiary center. 黎巴嫩骨肿瘤流行病学：一项2000年至2022年在三级中心进行的回顾性研究。
IF 2.5
Future Science OA Pub Date : 2023-08-08 eCollection Date: 2023-10-01 DOI: 10.2144/fsoa-2023-0102
Mohammad Daher, Ziad Zalaquett, Elio Mekhael, Marven Aoun, Ralph Chalhoub, Majd Abdo, Marc Aoude, Sami Abi Farraj, Ali Ghoul, Jean Tarchichi, Joe Rassi, Amer Sebaaly, Viviane Trak-Smayra, Carole Kesrouani, Hampig-Raphaël Kourie, Ismat Ghanem
{"title":"Epidemiology of bone tumors in Lebanon: a retrospective study from 2000 to 2022 at a tertiary center.","authors":"Mohammad Daher,&nbsp;Ziad Zalaquett,&nbsp;Elio Mekhael,&nbsp;Marven Aoun,&nbsp;Ralph Chalhoub,&nbsp;Majd Abdo,&nbsp;Marc Aoude,&nbsp;Sami Abi Farraj,&nbsp;Ali Ghoul,&nbsp;Jean Tarchichi,&nbsp;Joe Rassi,&nbsp;Amer Sebaaly,&nbsp;Viviane Trak-Smayra,&nbsp;Carole Kesrouani,&nbsp;Hampig-Raphaël Kourie,&nbsp;Ismat Ghanem","doi":"10.2144/fsoa-2023-0102","DOIUrl":"10.2144/fsoa-2023-0102","url":null,"abstract":"<p><strong>Aim: </strong>Bone tumors are rare and have an uneven geographic distribution.</p><p><strong>Methods: </strong>730 patients diagnosed with bone tumors were included in this retrospective analysis.</p><p><strong>Results: </strong>With a 64% rate of malignancy, the most common tumors were metastasis (40%) mostly in the axial skeleton, Osteosarcoma (9%) mostly in the femur, Osteochondroma (8%) mostly in the femur, giant cell tumors (7%) mostly in the knee, and Ewing's sarcoma (6%) mostly in the axial skeleton.</p><p><strong>Conclusion: </strong>Even though a some of the tumors have a predilection for certain localizations in the human body, they may differ in the middle-eastern population. One must also pay attention to the higher rates of malignancies as compared with other cohorts.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 9","pages":"FSO886"},"PeriodicalIF":2.5,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41105806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Association between hemoglobin variants and laboratory outcomes in patients infected with P. falciparum from South West Uganda. 乌干达西南部感染恶性疟原虫患者血红蛋白变异与实验室结果之间的关系
IF 2.5
Future Science OA Pub Date : 2023-08-01 DOI: 10.2144/fsoa-2022-0067
Hope Onohuean, Fanny Eseohe Onohuean, Ebere Emilia Ayogu
{"title":"Association between hemoglobin variants and laboratory outcomes in patients infected with <i>P. falciparum</i> from South West Uganda.","authors":"Hope Onohuean,&nbsp;Fanny Eseohe Onohuean,&nbsp;Ebere Emilia Ayogu","doi":"10.2144/fsoa-2022-0067","DOIUrl":"https://doi.org/10.2144/fsoa-2022-0067","url":null,"abstract":"<p><strong>Aims: </strong>We assess the relationship between various hemoglobin variants and some hematological parameters packed cell volume, white blood cells (PCV, WBC) and parasitemia level of patients with malaria in the southwestern, Uganda.</p><p><strong>Methods: </strong>Patient were enrolled by rapid diagnostic tests (RDTs), confirmed by microscopy, and laboratory outcomes were determined.</p><p><strong>Results: </strong>Patients positive for malaria RDTs were 155, microscopic-confirmed <i>P. falciparum</i> parasites were 95 (61.29%) having hemoglobin variants HbAA and HbAS; 75 (78.95%) and 13 (13.68%), respectively. The laboratory outcomes showed mean, PCV (32.19 ± 4.83), WBC (5831.66 ± 2888.29) and <i>P. falciparum</i> parasitaemia density (32,605.45 ± 14031), while the hemoglobin variants mean values AA (39,008.85 ± 31,261.56), AC (15908 ± 10173.48), AS (16,561.46 ± 15,380.93), SC (30,524 ± 0.000) and SS(1652 ± 0.000) were significantly different from the total population (34,321.5 ± 21,924.26) parasite-density.</p><p><strong>Conclusion: </strong>Patients with hemoglobin variants HbAA had a significantly higher parasite-carrying capacity and PCV levels.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"9 7","pages":"FSO888"},"PeriodicalIF":2.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9867656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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