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CD4+ T-cell transcription factors predict phenoconversion in idiopathic rapid eye movement sleep behavior disorder. CD4+ T细胞转录因子可预测特发性快速眼动睡眠行为障碍的表型转换。
IF 2.4
Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-11-14 DOI: 10.1080/20565623.2024.2418821
Monica Pinoli, Michele Terzaghi, Franca Marino, Cristoforo Comi, Maurizio Versino, Marco Cosentino
{"title":"CD4+ T-cell transcription factors predict phenoconversion in idiopathic rapid eye movement sleep behavior disorder.","authors":"Monica Pinoli, Michele Terzaghi, Franca Marino, Cristoforo Comi, Maurizio Versino, Marco Cosentino","doi":"10.1080/20565623.2024.2418821","DOIUrl":"10.1080/20565623.2024.2418821","url":null,"abstract":"<p><p><b>Aim:</b> Early biomarkers of phenoconversion to neurodegeneration are crucial to identify individuals at high risk. In patients with idiopathic REM sleep behavior disorder (iRBD), the strongest risk factor for neurodegeneration, CD4<sup>+</sup> T cells exhibit a peculiar transcription factor pattern.<b>Objective:</b> To assess transcription factor mRNA levels in CD4<sup>+</sup> T cells as predictive biomarkers of phenoconversion in iRBD patients.<b>Methods:</b> iRBD patients were followed prospectively. ROC curve analysis and Kaplan-Meier curves were used to assess the discrimination between converters and non-converters.<b>Results:</b> CD4<sup>+</sup> T cells from converters had higher <i>STAT1</i>, and lower <i>GATA3</i> and <i>FOXP3</i> mRNA levels. Hazard ratio was 58.3 (95% CI: 6.2-547.1) for higher <i>STAT1</i>, 101.2 (95% CI: 16.8-609.4) for lower <i>GATA3</i> and 15.7 (2.7-91.4) for lower <i>FOXP3</i>.<b>Conclusion:</b> <i>STAT1</i>, <i>GATA3</i> and <i>FOXP3</i> mRNA levels in CD4<sup>+</sup> T cells are promising predictive biomarkers of phenoconversion in iRBD patients.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"10 1","pages":"2418821"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between hypo-osmotic swelling test-induced tail swelling patterns and sperm quality. 低渗透膨胀试验诱导的尾部膨胀模式与精子质量之间的关系。
IF 2.4
Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-10-17 DOI: 10.1080/20565623.2024.2410696
Salima Daoud, Olfa Abdelkefi, Afifa Sellami, Azza Bensalem, Nozha Chakroun, Tarek Rebai
{"title":"Association between hypo-osmotic swelling test-induced tail swelling patterns and sperm quality.","authors":"Salima Daoud, Olfa Abdelkefi, Afifa Sellami, Azza Bensalem, Nozha Chakroun, Tarek Rebai","doi":"10.1080/20565623.2024.2410696","DOIUrl":"https://doi.org/10.1080/20565623.2024.2410696","url":null,"abstract":"<p><p><b>Aim:</b> The current sperm selection procedure for intracytoplasmic sperm injection has limited ability to detect structural and functional abnormalities of the spermatozoa. The aim of this study was to investigate whether the degree of sperm tail swelling observed during hypo-osmotic swelling test (HOST) may predict sperm quality.<b>Materials & methods:</b> Sixty semen samples were collected from men investigated for couple infertility. For each sample, sperm parameters, HOST and sperm chromatin status were evaluated. The relationship between the different HOST-induced tail swelling patterns ('a' to 'g') and sperm quality was evaluated.<b>Results:</b> The HOST significantly correlated with higher sperm motility and vitality, and with better morphology and nuclear quality. The HOST grades 'b' and 'c' were associated with better motility (<i>p</i> < 0.05 and <i>p</i> < 0.01, respectively) and morphology (grade 'b', <i>p</i> < 0.001). While grade 'd' was associated with better motility and count (<i>p</i> < 0.05).<b>Conclusion:</b> Our results show that the pattern of sperm tail swelling is linked to sperm functional integrity. HOST grades 'b' and 'd' were associated with better sperm quality, suggesting their preferential use during routine sperm selection for intracytoplasmic sperm injection.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"10 1","pages":"2410696"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11487947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142462780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comprehensive approach for detection of biotin deficiency from dried blood spot samples using liquid chromatography-mass spectrometry. 利用液相色谱-质谱法从干血斑样本中检测生物素缺乏症的综合方法。
IF 2.4
Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-07-04 DOI: 10.1080/20565623.2024.2355038
Arya Raveendran, Ashutosh Gupta, Leslie E Lewis, Krishnananda Prabhu, Sudheer Moorkoth
{"title":"A comprehensive approach for detection of biotin deficiency from dried blood spot samples using liquid chromatography-mass spectrometry.","authors":"Arya Raveendran, Ashutosh Gupta, Leslie E Lewis, Krishnananda Prabhu, Sudheer Moorkoth","doi":"10.1080/20565623.2024.2355038","DOIUrl":"10.1080/20565623.2024.2355038","url":null,"abstract":"<p><p><b>Aim:</b> The aim of the present study is to develop a liquid chromatography-mass spectrometry method to measure two important biomarkers of biotin deficiency from dried blood spot samples for effective management of the disorder. <b>Materials & methods:</b> The method was developed on a liquid chromatography-mass spectrometry system using pentafluorophenyl column employing a mobile phase composition of methanol and water in the isocratic mode. A full validation of the method was performed as per relevant guidelines. <b>Results & conclusion:</b> Correlation between the results of dried blood spot and plasma method was evaluated to determine the interconvertibility of the method. The developed method was successfully applied for establishing the reference ranges for these biomarkers in the population of Udupi, a coastal district of South India.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"10 1","pages":"2355038"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141497776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thioctic acid shield against lipopolysaccharide depression and endoplasmic reticulum stress: GR7M/Homer/ATF6 signaling. 硫辛酸可抵御脂多糖抑制和内质网应激：GR7M/Homer/ATF6信号传导。
IF 2.4
Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-11-25 DOI: 10.1080/20565623.2024.2422791
Mai O Kadry, Rehab M Abdel-Megeed
{"title":"Thioctic acid shield against lipopolysaccharide depression and endoplasmic reticulum stress: GR7M/Homer/ATF6 signaling.","authors":"Mai O Kadry, Rehab M Abdel-Megeed","doi":"10.1080/20565623.2024.2422791","DOIUrl":"10.1080/20565623.2024.2422791","url":null,"abstract":"<p><p><b>Aim:</b> Endoplasmic reticulum stress triggers neuronal unfolded protein accumulation, contributing to the pathophysiology of depression psychiatric illnesses.<b>Materials & methods:</b> The brain-derived neurotrophic factor (<i>BDNF</i>), metabotropic glutamate receptor type 7 (<i>GRM7</i>), phosphoinisitol kinase-3 (<i>PIK3</i>), serine/threonine kinase 1 (<i>AKT</i>) and <i>Homer1</i> may afford an important signaling pathways in LPS induced depression rat model. Herein, thioctic acid, Burdock and propolis therapeutic index on lipopolysaccharide (LPS)-induced depression was monitored. <i>BDNF/PI3K/GR7M/ATF6/CHOP/XBP/AKT/Homer-1</i> signaling pathways also opened a novel avenue in the integration of synaptic neurotransmission.<b>Results:</b> The aforementioned treatments elevated GR7M/BDNF/GABA gene expression meanwhile decreased reactive oxygen species generation (Malondialdehyde/glutathione reductase/Total antioxidant capacity) and reduced the expression of <i>ATF6/CHOP/PI3K/AKT/XBP/Homer-1</i> post LPS elevation.<b>Conclusion:</b> Thioctic acid, propolis and Burdock are prospective therapeutic agents via <i>GRM7/BDNF/AKT/PI3K/ATF6/XBP/homer</i> -<i>1</i> signaling pathways in LPS-induced depression.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"10 1","pages":"2422791"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11591480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between SGLT2 inhibitor use and specific cancer types: a systematic review and meta-analysis. 使用 SGLT2 抑制剂与特定癌症类型之间的关系：系统回顾和荟萃分析。
IF 2.4
Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-09-30 DOI: 10.1080/20565623.2024.2400797
Muhammad Ishtiaq Obaid, Mohammad Saiem Shahzad, Fakhar Latif, Muhammad Hamza Khan, Moeez Akram, Syed Asad Mehdi Rizvi, Rana Muhammad Umer Nasrullah, Dayab Asad, Muhammad Adil Obaid
{"title":"Relationship between SGLT2 inhibitor use and specific cancer types: a systematic review and meta-analysis.","authors":"Muhammad Ishtiaq Obaid, Mohammad Saiem Shahzad, Fakhar Latif, Muhammad Hamza Khan, Moeez Akram, Syed Asad Mehdi Rizvi, Rana Muhammad Umer Nasrullah, Dayab Asad, Muhammad Adil Obaid","doi":"10.1080/20565623.2024.2400797","DOIUrl":"10.1080/20565623.2024.2400797","url":null,"abstract":"<p><p><b>Aim:</b> The study aimed to explore the incidence of cancer as an adverse event to SGLT2 inhibitors (SGLT2i) use in Type 2 diabetes.<b>Materials & methods:</b> The study followed PRISMA guidelines to pool RCTs conforming the inclusion criteria. Random effects model was used to pool risk ratios.<b>Results & conclusion:</b> After reviewing 19 studies, the analysis suggested a possible increased risk of reproductive, breast, thyroid, hematologic/lymphatic, urinary, skin and skeletal cancers with SGLT2i use. Conversely, lower incidences of respiratory and cardiovascular cancers were noted. However, these associations lacked statistical significance. Caution is advised in using SGLT2i due to potential cancer risks, especially in diabetic patients prone to cancer. More RCTs are essential due to limited research in this area.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"10 1","pages":"2400797"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444652/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Local recurrences for mixed germ cell tumors without scrotal violation, is metastatic disease around the corner? A case report. 无阴囊侵犯的混合生殖细胞瘤局部复发，转移性疾病指日可待？病例报告。
IF 2.4
Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-11-14 DOI: 10.1080/20565623.2024.2420543
Georges Abi Tayeh, Constance Michel, Xavier Durand
{"title":"Local recurrences for mixed germ cell tumors without scrotal violation, is metastatic disease around the corner? A case report.","authors":"Georges Abi Tayeh, Constance Michel, Xavier Durand","doi":"10.1080/20565623.2024.2420543","DOIUrl":"10.1080/20565623.2024.2420543","url":null,"abstract":"<p><p>We hereby report the case of a 40-year-old male, who initially underwent a left inguinal orchiectomy for a stage Is mixed germ cell tumor achieving an R0 status. His follow-up is mainly noticeable for many recurrences affecting exclusively the inguinal and suprapubic soft tissues. The recurrences occurred early, and almost always contained immature tissue upon pathologic reading, which has never been described in the medical literature before.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"10 1","pages":"2420543"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unveiling the crisis: cocaine abuse's deadly connection to heart disease in Pakistan. 揭开危机的面纱：巴基斯坦可卡因滥用与心脏病的致命联系。
IF 2.4
Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-11-14 DOI: 10.1080/20565623.2024.2419331
Jawad Ghias Shaikh, Ahmed Asad Raza, Muhammad Abdul Qadeer
{"title":"Unveiling the crisis: cocaine abuse's deadly connection to heart disease in Pakistan.","authors":"Jawad Ghias Shaikh, Ahmed Asad Raza, Muhammad Abdul Qadeer","doi":"10.1080/20565623.2024.2419331","DOIUrl":"10.1080/20565623.2024.2419331","url":null,"abstract":"","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"10 1","pages":"2419331"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary actinomycosis complicating COVID-19 pneumonia in an immunocompetent patient: a case report. 免疫功能正常患者并发 COVID-19 肺炎的肺放线菌病：病例报告。
IF 2.4
Future Science OA Pub Date : 2024-12-31 Epub Date: 2024-11-21 DOI: 10.1080/20565623.2024.2411931
Narjes Abid, Manel Loukil, Ella Nemsi, Abir Chaabane, Siwar Sbaihi, Nada Gader, Khaoula Hemissi, Hedia Ghrairi
{"title":"Pulmonary actinomycosis complicating COVID-19 pneumonia in an immunocompetent patient: a case report.","authors":"Narjes Abid, Manel Loukil, Ella Nemsi, Abir Chaabane, Siwar Sbaihi, Nada Gader, Khaoula Hemissi, Hedia Ghrairi","doi":"10.1080/20565623.2024.2411931","DOIUrl":"10.1080/20565623.2024.2411931","url":null,"abstract":"<p><p>Several co-infections have been described in the context of COVID-19 but only few cases of actinomycosis following SARS-CoV-2 infection have been reported in the literature. We report here the observation of a 48-year-old man, a smoker, who presented, in the aftermath of COVID-19 pneumonia requiring oxygen therapy a pyopneumothorax treated with antibiotic therapy and chest drainage. A few days later, he presented with hemoptysis. The diagnosis of actinomycosis was made based on histopathological data from endoscopic biopsies. The outcome was favorable under adapted and prolonged antibiotic therapy with amoxicillin. Pulmonary actinomycosis, although rare, should be suspected in front of lingering respiratory symptoms and/or atypical radiological findings in the context of a COVID-19.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"10 1","pages":"2411931"},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11583601/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142681428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unraveling disulfidptosis for prognostic modeling and personalized treatment strategies in lung adenocarcinoma. 为肺腺癌的预后建模和个性化治疗策略揭开二硫化钼的神秘面纱。
IF 2.4
Future Science OA Pub Date : 2024-12-01 Epub Date: 2024-11-25 DOI: 10.1080/20565623.2024.2432211
Xiangyu Xu, Bingbing Zhang, Jin Zhang, Hongbiao Ma
{"title":"Unraveling disulfidptosis for prognostic modeling and personalized treatment strategies in lung adenocarcinoma.","authors":"Xiangyu Xu, Bingbing Zhang, Jin Zhang, Hongbiao Ma","doi":"10.1080/20565623.2024.2432211","DOIUrl":"10.1080/20565623.2024.2432211","url":null,"abstract":"<p><strong>Aim: </strong>To construct and identify a prognostic and therapeutic signature based on disulfidptosis-related genes in lung adenocarcinoma.</p><p><strong>Methods: </strong>Bioinformatic analysis was performed to assess the differential expression of disulfidptosis-related genes between cancerous and control samples from The Cancer Genome Atlas-Lung Adenocarcinoma (TCGA-LUAD) database. Survival analysis, immune cell infiltration assessment, and examination of oncogenic pathways were performed to uncover potential clinical implications of disulfidptosis gene expression. Differential gene expression analysis between subtypes facilitated the development of a prognostic model using a combination of genes associated with survival. A nomogram was further created using independent clinical and molecular factors.</p><p><strong>Results: </strong>We identified the significant upregulation of ten disulfidptosis-related genes and delineated two distinct subtypes, C1 and C2. Subtype C2 was associated with prolonged survival. Then, prognostic modeling utilizing six genes (TXNRD1, CPS1, S100P, SCGB3A1, CYP24A1, NAPSA) demonstrated predictive power in both training and validation datasets. The nomogram, incorporating the risk model with clinical features, provided a reliable tool for predicting one-year (AUC 0.77), three-year (AUC 0.75), and five-year (AUC 0.78) survival rates. Additionally, chemotherapy sensitivity analysis highlighted significant resistance in the high-risk group, primarily associated with subtype C1.</p><p><strong>Conclusion: </strong>Our study reveals distinct LUAD subtypes, offers a robust prognostic model, and underscores clinical implications for personalized therapy based on disulfidptosis-related genes expression profiles.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"10 1","pages":"2432211"},"PeriodicalIF":2.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phase I study of allogeneic monocyte-derived inflammatory dendritic cells in combination with pembrolizumab. 异体单核细胞衍生炎性树突状细胞联合 pembrolizumab 的 I 期研究。
IF 2.4
Future Science OA Pub Date : 2024-12-01 Epub Date: 2024-11-20 DOI: 10.1080/20565623.2024.2426426
Jared Weiss, Douglas Laux, David Bajor, Albert C Lockhart, John Hamm, Jeroen Rovers, Alex Karlsson-Parra
{"title":"Phase I study of allogeneic monocyte-derived inflammatory dendritic cells in combination with pembrolizumab.","authors":"Jared Weiss, Douglas Laux, David Bajor, Albert C Lockhart, John Hamm, Jeroen Rovers, Alex Karlsson-Parra","doi":"10.1080/20565623.2024.2426426","DOIUrl":"10.1080/20565623.2024.2426426","url":null,"abstract":"<p><p>PD-1 checkpoint inhibition has revolutionized the care of cancer. A small portion of patients with stage IV cancer achieve durable control. But, early progression is common and dramatic control is achieved for only a minority. We hypothesized that ilixadencel, an allogeneic monocyte-derived dendritic cell product could be injected into tumor to potentiate PD-1 response and thus conducted a phase I study of pembrolizumab plus ilixadencel. Twenty-one patients were accrued. The most common treatment emergent adverse events were fatigue, injection site pain, anemia, weight decreased and hyponatremia, mostly grade 1-2. No dose limiting toxicities were observed and the recommended phase II dose was established at 10 million cells administered twice. Two unconfirmed responses were observed, with no confirmed responses.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"10 1","pages":"2426426"},"PeriodicalIF":2.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11581178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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