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Adherence and barriers to Mediterranean diet in Tunisian patients with nonalcoholic fatty liver disease 突尼斯非酒精性脂肪肝患者坚持地中海饮食的情况和障碍
IF 2.5
Future Science OA Pub Date : 2024-01-01 DOI: 10.2144/fsoa-2023-0140
Ayadi Shema, Trad Nouha, Krifa Nesrine, Mensi Asma, Belhadj Mabrouk Emna, Mouelhi Leila, Dabbeche Radhouene
{"title":"Adherence and barriers to Mediterranean diet in Tunisian patients with nonalcoholic fatty liver disease","authors":"Ayadi Shema, Trad Nouha, Krifa Nesrine, Mensi Asma, Belhadj Mabrouk Emna, Mouelhi Leila, Dabbeche Radhouene","doi":"10.2144/fsoa-2023-0140","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0140","url":null,"abstract":"Aim: The burden of non alcoolic fatty liver disease (NAFLD) is globally increasing. While crucial for management, NAFLD patient adherence to the Mediterranean diet (MD) is underexplored, especially in Mediterranean countries such as Tunisia. Materials & methods: A prospective study (Nov 2022–Feb 2023) supervised MD introduction by a nutritionist, evaluated adherence with MEDAS scores (≥10 for good compliance), and explored barriers to good adherence. Results: Among 41 patients (11 male/30 female, mean age 56 [29–70]), 63% had low education and 51% had metabolic syndrome. Good MD adherence stood at 14.6%. Poor adherence tied to diet-induced higher costs (p = 0.021) and difficulty to new-diet adoption (p = 0.026). Conclusion: Tunisian NAFLD patients had low MD adherence due to financial constraints and dietary adaptation challenges.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140520176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Haloperidol-induced painless legs and moving toe syndrome in a schizophrenia patient: a case report 精神分裂症患者氟哌啶醇诱发的无痛腿和动趾综合征：病例报告
IF 2.5
Future Science OA Pub Date : 2024-01-01 DOI: 10.2144/fsoa-2023-0207
Mugundan U Maheshwari, Natarajan Shanmugasundaram, Karthik Sankar, M. Sekar, Ling S Wong, Sarvesh Sabarathinam, M. Y. Begum, S. Jeyabalan
{"title":"Haloperidol-induced painless legs and moving toe syndrome in a schizophrenia patient: a case report","authors":"Mugundan U Maheshwari, Natarajan Shanmugasundaram, Karthik Sankar, M. Sekar, Ling S Wong, Sarvesh Sabarathinam, M. Y. Begum, S. Jeyabalan","doi":"10.2144/fsoa-2023-0207","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0207","url":null,"abstract":"Painless legs and moving toe syndrome (PoLMT) is a rare syndrome characterized by involuntary movements of the toe without pain. The exact etiology of the patient's PoLMT is unknown. We present a case of PoLMT in 45-year-old woman with a history of haloperidol intake for 10 months. Haloperidol was discontinued, and aripiprazole (15 mg) was initiated. After this switch, a reduction in movement was observed in the third and fourth toes; however, the second toe showed no discernible change.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140515737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Green biologically synthesized metal nanoparticles: biological applications, optimizations and future prospects 绿色生物合成金属纳米颗粒：生物应用、优化和未来展望
IF 2.5
Future Science OA Pub Date : 2024-01-01 DOI: 10.2144/fsoa-2023-0196
Radwa N Morgan, K. Aboshanab
{"title":"Green biologically synthesized metal nanoparticles: biological applications, optimizations and future prospects","authors":"Radwa N Morgan, K. Aboshanab","doi":"10.2144/fsoa-2023-0196","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0196","url":null,"abstract":"In green biological synthesis, metal nanoparticles are produced by plants or microorganisms. Since it is ecologically friendly, economically viable and sustainable, this method is preferable to other traditional ones. For their continuous groundbreaking advancements and myriad physiochemical and biological benefits, nanotechnologies have influenced various aspects of scientific fields. Metal nanoparticles (MNPs) are the field anchor for their outstanding optical, electrical and chemical capabilities that outperform their regular-sized counterparts. This review discusses the most current biosynthesized metal nanoparticles synthesized by various organisms and their biological applications along with the key elements involved in MNP green synthesis. The review is displayed in a manner that will impart assertiveness, help the researchers to open questions, and highlight many points for conducting future research.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140523019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D-printed nanomedicines for cancer therapy 用于癌症治疗的 3D 打印纳米药物
IF 2.5
Future Science OA Pub Date : 2024-01-01 DOI: 10.2144/fsoa-2024-0039
Surbhi Bisht, Sweta Kanwal, B. M. Gnanamangai, Swati Singh, Devayatbhai Baku Mansi, Ranvijay Kumar, Mayank Sharma, P. K. Gupta
{"title":"3D-printed nanomedicines for cancer therapy","authors":"Surbhi Bisht, Sweta Kanwal, B. M. Gnanamangai, Swati Singh, Devayatbhai Baku Mansi, Ranvijay Kumar, Mayank Sharma, P. K. Gupta","doi":"10.2144/fsoa-2024-0039","DOIUrl":"https://doi.org/10.2144/fsoa-2024-0039","url":null,"abstract":"","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140521431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validating LENT score in malignant pleural effusion 验证恶性胸腔积液的 LENT 评分
IF 2.5
Future Science OA Pub Date : 2024-01-01 DOI: 10.2144/fsoa-2023-0168
Alia Alawneh, Fadi Abu Farsakh, Mahmoud Smadi, Shaher Samrah
{"title":"Validating LENT score in malignant pleural effusion","authors":"Alia Alawneh, Fadi Abu Farsakh, Mahmoud Smadi, Shaher Samrah","doi":"10.2144/fsoa-2023-0168","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0168","url":null,"abstract":"Aim: LENT score was developed to predict survival in malignant pleural effusion (MPE), this study aims to validate this score. Objectives: Validate LENT Prognostic Score for MPE and explore survival in these patients. Methods: Retrospective analysis of 202 patients who had MPE and received drainage between January 2013 and June 2015. Results: Median survival was 2.98 months. Patients were classified according to LENT score as low, moderate and high-risk groups: 5 (4.2%), 61 (50.8%), and 54 (45%), respectively. Kaplan–Meier curve showed median survival for each group: 9.41, 5.36 and 0.56 months, respectively, p-values <0.001. AUC for 1, 3 and 6 months: 0.741, 0.781, 0.790, respectively, p-values <0.001. Conclusion: LENT score is valid for predicting survival in patients with MPE.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140523303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vaping epidemic among the youth in Pakistan: urgent measures required to combat the rising trend 巴基斯坦年轻人中流行吸食毒品：需要采取紧急措施应对这一上升趋势
IF 2.5
Future Science OA Pub Date : 2024-01-01 DOI: 10.2144/fsoa-2024-0011
Shahzaib Samad, Bilqees Baloch, M. A. Qadeer
{"title":"Vaping epidemic among the youth in Pakistan: urgent measures required to combat the rising trend","authors":"Shahzaib Samad, Bilqees Baloch, M. A. Qadeer","doi":"10.2144/fsoa-2024-0011","DOIUrl":"https://doi.org/10.2144/fsoa-2024-0011","url":null,"abstract":"","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140515810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Welcome to volume 10 of Future Science OA 欢迎阅读《未来科学 OA》第 10 卷
IF 2.5
Future Science OA Pub Date : 2024-01-01 DOI: 10.2144/fsoa-2023-0283
Megan Bryant
{"title":"Welcome to volume 10 of Future Science OA","authors":"Megan Bryant","doi":"10.2144/fsoa-2023-0283","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0283","url":null,"abstract":"","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140523772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multi-epitope vaccine against SARS-CoV-2 targeting the spike RBD: an immunoinformatics approach 针对尖峰 RBD 的 SARS-CoV-2 多表位疫苗：一种免疫信息学方法
IF 2.5
Future Science OA Pub Date : 2024-01-01 DOI: 10.2144/fsoa-2023-0081
Y. Pahlavan, Omid Yeganeh, Vahid Asghariazar, Chiman Karami
{"title":"Multi-epitope vaccine against SARS-CoV-2 targeting the spike RBD: an immunoinformatics approach","authors":"Y. Pahlavan, Omid Yeganeh, Vahid Asghariazar, Chiman Karami","doi":"10.2144/fsoa-2023-0081","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0081","url":null,"abstract":"Aim: We designed a SARS-CoV-2 epitope vaccine based on the receptor-binding domain (RBD) in virus spike protein. Methods: RT-PCR performed on nasopharyngeal swab COVID-19 patients. After registering RBD region in the GenBank, physicochemical parameters, secondary structure, homology modeling, 3D structure of RBD region and antigenicity were determined using ProtParam ExPASy, PSIPRED, MolProbity, IEDB and Vaxijen online tools, respectively. Results: B and T cell epitopes were predicted in terms of non-allergenicity and antigenicity. MolProbity analysis provided a qualitative model for RBD. The homology model showed that most of the residues are in optimal district of energy. Conclusion: High immunogenicity score of epitopes indicates promising candidates for the development of multi-epitope vaccines. It may help to develop an effective vaccine.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140518583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parents of children with autism spectrum disorder quality of life in Jordan: a comparative study 约旦自闭症谱系障碍儿童家长的生活质量：一项比较研究
IF 2.5
Future Science OA Pub Date : 2023-12-21 DOI: 10.2144/fsoa-2023-0096
Abedallah Kasem, S. Abuhammad, Naemah Jamal
{"title":"Parents of children with autism spectrum disorder quality of life in Jordan: a comparative study","authors":"Abedallah Kasem, S. Abuhammad, Naemah Jamal","doi":"10.2144/fsoa-2023-0096","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0096","url":null,"abstract":"Aim: This study aimed to assess the quality of life (QoL) of parents of children with autism spectrum disorder (ASD) in Jordan and its associated factors. Methods: This comparative study was conducted among parents of children with ASD and non-ASD. Data collection took four setting areas that include three centers for autism in three different municipalities and the control group was collected using social media. A convenience sample of 242 parents agreed to complete a QoL questionnaire. Results: Parents of children with ASD in Jordan have poor QoL across the five domains of QoL in compare with parents with non-ASD child. Factors such as gender, level of education, living condition and employment status were found impacting QoL.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138953118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Squamous cell carcinoma and Crohn's disease: a sometimes-challenging diagnosis 鳞状细胞癌和克罗恩病：有时很棘手的诊断方法
IF 2.5
Future Science OA Pub Date : 2023-12-12 DOI: 10.2144/fsoa-2023-0109
Mona Boudabbous, Baha Barkia, W. Feki, H. Gdoura, L. Chtourou, M. Moalla, L. Mnif, A. Amouri, Zeinab Mnif, N. Tahri
{"title":"Squamous cell carcinoma and Crohn's disease: a sometimes-challenging diagnosis","authors":"Mona Boudabbous, Baha Barkia, W. Feki, H. Gdoura, L. Chtourou, M. Moalla, L. Mnif, A. Amouri, Zeinab Mnif, N. Tahri","doi":"10.2144/fsoa-2023-0109","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0109","url":null,"abstract":"Aim: Non-melanoma skin cancers are more common in people with inflammatory bowel disease. However, these tumors can rarely mimic a cutaneous manifestation of the disease, which delays diagnosis and clouds prognosis. Observation: A 35-year-old man with stenosing and fistulizing ileocolic Crohn's disease developed squamous cell carcinoma mimicking a groin fold abscess. After surgical drainage of the abscess, despite antibiotics and therapy combining azathioprine with infliximab, the abscess has recurred. Biopsies revealed a cutaneous squamous cell carcinoma. Palliative radiotherapy-chemotherapy was initiated, but the patient died after 3 months. Conclusion: This observation illustrates the increased risk of non-melanoma skin cancers in inflammatory bowel disease patients, particularly those exposed to thiopurines, and the value of diagnosing them at an early stage.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139007838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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