Haythem Elaskri, Sadri Ben Abid, Alaa Oueslati, Sondes Bizid, Sonia Ben Ali, Omar Beskri, Arine Aouadi, Issam Msakni, Hatem Ben Abdallah, Iheb Labbene
{"title":"年轻女性可卡因相关性非闭塞性缺血性结肠炎模拟阑尾炎1例报告。","authors":"Haythem Elaskri, Sadri Ben Abid, Alaa Oueslati, Sondes Bizid, Sonia Ben Ali, Omar Beskri, Arine Aouadi, Issam Msakni, Hatem Ben Abdallah, Iheb Labbene","doi":"10.1080/20565623.2025.2570011","DOIUrl":null,"url":null,"abstract":"<p><p>Cocaine can trigger severe splanchnic vasoconstriction and non-occlusive mesenteric ischemia, occasionally mimicking common surgical emergencies. A previously healthy 27-year-old woman presented with 5 days of worsening right lower quadrant pain, nausea, and fever. CT suggested appendicitis. Laparoscopy revealed a normal appendix but ischemic ileum and cecal gangrene, requiring conversion to laparotomy and ileocecal resection with stoma. Histopathology showed transmural ischemic necrosis without vascular occlusion. Postoperatively, the patient disclosed recent cocaine use. Cocaine-related ischemia often affects young adults without vascular risk factors, may be radiologically subtle, and carries higher mortality when diagnosis is delayed. In young adults with unexplained acute abdomen, clinicians should consider cocaine-associated ischemia and obtain toxicology screening when the etiology is unclear, enabling timely management and improved outcomes.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":"11 1","pages":"2570011"},"PeriodicalIF":2.1000,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cocaine-associated non-occlusive ischemic colitis mimicking appendicitis in a young woman: a case report.\",\"authors\":\"Haythem Elaskri, Sadri Ben Abid, Alaa Oueslati, Sondes Bizid, Sonia Ben Ali, Omar Beskri, Arine Aouadi, Issam Msakni, Hatem Ben Abdallah, Iheb Labbene\",\"doi\":\"10.1080/20565623.2025.2570011\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Cocaine can trigger severe splanchnic vasoconstriction and non-occlusive mesenteric ischemia, occasionally mimicking common surgical emergencies. A previously healthy 27-year-old woman presented with 5 days of worsening right lower quadrant pain, nausea, and fever. CT suggested appendicitis. Laparoscopy revealed a normal appendix but ischemic ileum and cecal gangrene, requiring conversion to laparotomy and ileocecal resection with stoma. Histopathology showed transmural ischemic necrosis without vascular occlusion. Postoperatively, the patient disclosed recent cocaine use. Cocaine-related ischemia often affects young adults without vascular risk factors, may be radiologically subtle, and carries higher mortality when diagnosis is delayed. In young adults with unexplained acute abdomen, clinicians should consider cocaine-associated ischemia and obtain toxicology screening when the etiology is unclear, enabling timely management and improved outcomes.</p>\",\"PeriodicalId\":12568,\"journal\":{\"name\":\"Future Science OA\",\"volume\":\"11 1\",\"pages\":\"2570011\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Future Science OA\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/20565623.2025.2570011\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/10/10 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future Science OA","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/20565623.2025.2570011","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/10/10 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
Cocaine-associated non-occlusive ischemic colitis mimicking appendicitis in a young woman: a case report.
Cocaine can trigger severe splanchnic vasoconstriction and non-occlusive mesenteric ischemia, occasionally mimicking common surgical emergencies. A previously healthy 27-year-old woman presented with 5 days of worsening right lower quadrant pain, nausea, and fever. CT suggested appendicitis. Laparoscopy revealed a normal appendix but ischemic ileum and cecal gangrene, requiring conversion to laparotomy and ileocecal resection with stoma. Histopathology showed transmural ischemic necrosis without vascular occlusion. Postoperatively, the patient disclosed recent cocaine use. Cocaine-related ischemia often affects young adults without vascular risk factors, may be radiologically subtle, and carries higher mortality when diagnosis is delayed. In young adults with unexplained acute abdomen, clinicians should consider cocaine-associated ischemia and obtain toxicology screening when the etiology is unclear, enabling timely management and improved outcomes.
期刊介绍:
Future Science OA is an online, open access, peer-reviewed title from the Future Science Group. The journal covers research and discussion related to advances in biotechnology, medicine and health. The journal embraces the importance of publishing all good-quality research with the potential to further the progress of research in these fields. All original research articles will be considered that are within the journal''s scope, and have been conducted with scientific rigour and research integrity. The journal also features review articles, editorials and perspectives, providing readers with a leading source of commentary and analysis. Submissions of the following article types will be considered: -Research articles -Preliminary communications -Short communications -Methodologies -Trial design articles -Trial results (including early-phase and negative studies) -Reviews -Perspectives -Commentaries