年轻女性可卡因相关性非闭塞性缺血性结肠炎模拟阑尾炎1例报告。

IF 2.1 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Future Science OA Pub Date : 2025-12-01 Epub Date: 2025-10-10 DOI:10.1080/20565623.2025.2570011
Haythem Elaskri, Sadri Ben Abid, Alaa Oueslati, Sondes Bizid, Sonia Ben Ali, Omar Beskri, Arine Aouadi, Issam Msakni, Hatem Ben Abdallah, Iheb Labbene
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引用次数: 0

摘要

可卡因可以引发严重的内脏血管收缩和非闭塞性肠系膜缺血,偶尔会模仿常见的外科急诊。先前健康的27岁女性表现为5天恶化的右下腹疼痛,恶心和发烧。CT提示阑尾炎。腹腔镜检查显示阑尾正常,但回肠缺血性和盲肠坏疽,需要转开腹手术和回盲切除并造口。组织病理学表现为无血管闭塞的全壁缺血性坏死。术后,患者透露近期使用可卡因。可卡因相关性缺血通常影响没有血管危险因素的年轻人,可能在放射学上很微妙,如果诊断延迟,死亡率会更高。对于患有不明原因急腹症的年轻人,当病因不明时,临床医生应考虑可卡因相关性缺血,并进行毒理学筛查,以便及时处理并改善预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cocaine-associated non-occlusive ischemic colitis mimicking appendicitis in a young woman: a case report.

Cocaine can trigger severe splanchnic vasoconstriction and non-occlusive mesenteric ischemia, occasionally mimicking common surgical emergencies. A previously healthy 27-year-old woman presented with 5 days of worsening right lower quadrant pain, nausea, and fever. CT suggested appendicitis. Laparoscopy revealed a normal appendix but ischemic ileum and cecal gangrene, requiring conversion to laparotomy and ileocecal resection with stoma. Histopathology showed transmural ischemic necrosis without vascular occlusion. Postoperatively, the patient disclosed recent cocaine use. Cocaine-related ischemia often affects young adults without vascular risk factors, may be radiologically subtle, and carries higher mortality when diagnosis is delayed. In young adults with unexplained acute abdomen, clinicians should consider cocaine-associated ischemia and obtain toxicology screening when the etiology is unclear, enabling timely management and improved outcomes.

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来源期刊
Future Science OA
Future Science OA MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
5.00
自引率
4.00%
发文量
48
审稿时长
13 weeks
期刊介绍: Future Science OA is an online, open access, peer-reviewed title from the Future Science Group. The journal covers research and discussion related to advances in biotechnology, medicine and health. The journal embraces the importance of publishing all good-quality research with the potential to further the progress of research in these fields. All original research articles will be considered that are within the journal''s scope, and have been conducted with scientific rigour and research integrity. The journal also features review articles, editorials and perspectives, providing readers with a leading source of commentary and analysis. Submissions of the following article types will be considered: -Research articles -Preliminary communications -Short communications -Methodologies -Trial design articles -Trial results (including early-phase and negative studies) -Reviews -Perspectives -Commentaries
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