Geriatrics & Gerontology International最新文献

{"title":"Multimorbidity patterns and disability risk in aging populations: Insights from machine learning.","authors":"Zilin Zhao, Fei Xu, Hejia Wan","doi":"10.1111/ggi.70175","DOIUrl":"https://doi.org/10.1111/ggi.70175","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145039948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender differences in roles of health behavior between marital status and oral health","authors":"Farzana Sharmin,&nbsp;Yusuke Matsuyama,&nbsp;Shiho Kino,&nbsp;Sakura Kiuchi,&nbsp;Katsunori Kondo,&nbsp;Jun Aida","doi":"10.1111/ggi.70170","DOIUrl":"10.1111/ggi.70170","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Marital status is a form of social network and source of social support, and it is beneficial to oral health by enhancing health behaviors. We examined the mediating effects of oral health behaviors on the association of marital status with the number of teeth.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This cross-sectional study used data from the Japan Gerontological Evaluation Study 2022, targeting individuals aged ≥65 years. Marital status was the exposure, and the number of teeth was the outcome. Mediation effects of dental treatment, dental checkup, tooth brushing, alcohol drinking, and smoking were evaluated using the Karlson–Holm–Breen (KHB) method.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 21 745 participants, the mean number of teeth was higher in participants having a spouse (men: 18.49 [standard deviation, SD = 10.00], women: 20.08 [SD = 8.88]) than in those without a spouse (men: 16.34 [SD = 10.34], women: 17.22 [SD = 10.35]). Having a spouse was associated with a higher number of teeth, yielding coefficients of 0.76 (95% confidence interval [CI] = 0.26; 1.25) for men and 0.67 (95% CI = 0.31; 1.03) for women, after adjusting for confounders. The coefficients for the association through oral health behaviors were 0.66 (95% CI = 0.51; 0.81) for men and 0.10 (95% CI = 0.02; 0.19) for women, explaining 46.62% of the association in men and 13.68% in women.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Being married at an older age was associated with having a higher number of teeth, which was mediated by better oral health behaviors. These behaviors had a greater impact on men, who generally had poorer behaviors compared with women. <b>Geriatr Gerontol Int 2025; 25: 1397–1403</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 10","pages":"1397-1403"},"PeriodicalIF":2.5,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.70170","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145039974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on “Comparative analysis of the maximal respiratory pressure and peak expiratory flow rate in diagnosing probable respiratory sarcopenia: The Otassha study”","authors":"Prajnasini Satapathy,&nbsp;Rachana Mehta,&nbsp;Ranjana Sah","doi":"10.1111/ggi.70162","DOIUrl":"10.1111/ggi.70162","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 10","pages":"1450-1451"},"PeriodicalIF":2.5,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic persistence in geriatric medicine: A case of VEXAS syndrome in an older adult","authors":"Lynn Goovaerts,&nbsp;Roma Fourmanov,&nbsp;Ariëla Loupatty,&nbsp;Bart Spaetgens,&nbsp;Renée A.G. Brüggemann","doi":"10.1111/ggi.70169","DOIUrl":"10.1111/ggi.70169","url":null,"abstract":"&lt;p&gt;In geriatric medicine, the need to balance thorough diagnostic evaluation with the potential burden of invasive testing is a well-known dilemma. Older adults often present with vague or nonspecific symptoms in the context of multimorbidity, which frequently leads to a pragmatic, symptom-oriented approach rather than an in-depth search for rare underlying conditions. However, a conservative diagnostic approach, although often justified, can delay the recognition of treatable diseases. The combination of diagnostic complexity and the high prevalence of nonspecific inflammatory syndromes increases the risk of missed or delayed diagnoses.&lt;/p&gt;&lt;p&gt;This case highlights the value of diagnostic persistence in such contexts: a 75-year-old man with unexplained systemic inflammation ultimately diagnosed with VEXAS syndrome.&lt;/p&gt;&lt;p&gt;The patient presented to the outpatient geriatric clinic with an 8-month history of unintentional weight loss, fatigue, night sweats and progressive exertional dyspnea. He also experienced diffuse arthralgia without joint inflammation, and intermittent, stabbing pains affecting various parts of the body, which resolved spontaneously within minutes (Fig. 1a). His medical history included type 2 diabetes, atrial fibrillation and a recently treated gastric ulcer.&lt;/p&gt;&lt;p&gt;Physical examination was unremarkable. Blood pressure was 136/86 mmHg, pulse 106 b.p.m. and body mass index 23 (current weight 73 kg). Cardiopulmonary examination revealed an irregular rhythm consistent with atrial fibrillation. No cardiac murmur, endocarditis stigmata, lymphadenopathy, joint swelling or skin abnormalities were observed. Initial laboratory testing revealed an elevated erythrocyte sedimentation rate (122 mm/h), mild macrocytic anemia (hemoglobin 7.7 mmol/L, mean corpuscular volume 102 fL) and hyperferritinemia (439 μg/L). White blood cell and platelet counts were normal. Peripheral blood smear showed atypical lymphocytes and toxic granulation. Electrolytes, C-reactive protein, renal and liver function, lactic dehydrogenase, and vitamin levels were normal. Extensive microbiological testing (including blood cultures, cytomegalovirus/Epstein–Barr virus, hepatitis B/C, HIV, parvovirus B19/toxoplasma/&lt;i&gt;Coxiella burnetii&lt;/i&gt;) was negative. Immunological workup showed hypergammaglobulinemia and type III mixed cryoglobulinemia with positive rheumatoid factor, whereas antinuclear antibodies and antineutrophil cytoplasmic antibodies were negative.&lt;/p&gt;&lt;p&gt;A positron emission tomography scan showed diffuse bone marrow activation (Fig. 1b,c) without signs of malignancy, vasculitis or systemic rheumatic disease. Due to persistent symptoms and worsening anemia (hemoglobin 6.4 mmol/L), the patient was referred to hematology. Bone marrow aspiration showed a hypercellular bone marrow with mild hypergranulopoeisis and preserved maturation, initially considered reactive. However, cytogenetic analysis subsequently showed a somatic UBA1 mutation (exon 3, c.122T&gt;C p.(Met41","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 10","pages":"1429-1430"},"PeriodicalIF":2.5,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.70169","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic importance of the reason for six-minute walk test interruption in hospitalized older patients with heart failure.","authors":"Hiroshi Saito, Daichi Maeda, Nobuyuki Kagiyama, Tsutomu Sunayama, Taishi Dotare, Yudai Fujimoto, Taisuke Nakade, Kentaro Jujo, Kazuya Saito, Kentaro Kamiya, Yuki Ogasahara, Emi Maekawa, Masaaki Konishi, Takeshi Kitai, Kentaro Iwata, Hiroshi Wada, Takatoshi Kasai, Hirofumi Nagamatsu, Shin-Ichi Momomura, Akira Mizukami, Yuya Matsue","doi":"10.1111/ggi.70172","DOIUrl":"https://doi.org/10.1111/ggi.70172","url":null,"abstract":"<p><strong>Aim: </strong>The six-minute walk test (6MWT) allows patients to slow down, stop and rest as needed. However, the prognostic significance of 6MWT interruption remains unclear. Therefore, this study investigated the prognostic implications of 6MWT interruption in patients with heart failure (HF).</p><p><strong>Methods: </strong>Patients hospitalized with HF who underwent 6MWT before discharge were included. They were stratified into three groups: those who completed the 6MWT, those who interrupted the test because of dyspnea or leg fatigue and those who interrupted the test for other reasons. The primary outcome was 2-year mortality.</p><p><strong>Results: </strong>In total, 1180 patients were analyzed; 749 completed the 6MWT, 341 interrupted it because of dyspnea or leg fatigue and 90 interrupted it for other reasons. During the 2-year follow-up period, 238 patients (20.2%) died. In the Kaplan-Meier analysis, 6MWT interruption due to dyspnea/leg fatigue was associated with a significantly higher 2-year mortality rate, which remained significant even after adjustment for conventional risk factors, including the 6MWD and the Borg score measured after the 6MWT. However, 6MWT interruption for other reasons was not significantly associated with mortality.</p><p><strong>Conclusion: </strong>In hospitalized patients with HF, 6MWT interruption due to dyspnea or leg fatigue was independently associated with higher 2-year mortality, regardless of the 6MWD. These findings suggest that 6MWT interruption might be a valuable prognostic marker for HF management. Geriatr Gerontol Int 2025; ••: ••-••.</p>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between body composition and hospitalization in patients undergoing maintenance hemodialysis","authors":"Hae Eun Jeon,&nbsp;Hongtae Kim,&nbsp;Soie Kwon,&nbsp;Jungho Shin","doi":"10.1111/ggi.70167","DOIUrl":"10.1111/ggi.70167","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Patients undergoing maintenance hemodialysis (MHD) often have multiple comorbidities and are vulnerable to minor stressors that frequently result in hospitalization. Recent advances have enabled the easy estimation of body composition in clinical settings. This study retrospectively investigated changes in body composition associated with hospitalization in patients receiving MHD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Body composition was measured every 6 months using a multifrequency bioelectrical impedance analysis (BIA) device in outpatients with MHD. Hospitalization events lasting &gt;24 h were reviewed throughout the follow-up period.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Overall, 166 patients (94 men [56.6%]) underwent 904 BIA measurements. A higher baseline extracellular water to total body water ratio (ECW/TBW) and lower phase angle (PhA) were associated with increased hospitalization risk. During the study period, 272 hospitalizations were recorded. Compared with those without hospitalization, hospitalized patients showed progressive declines in fat-free mass index, skeletal muscle mass index, and PhA, along with an increase in ECW/TBW. These trends were consistent across subgroups based on the number and duration of hospitalizations; however, an increase in visceral fat area was observed in patients with four or more hospitalizations. Among the 89 patients who were hospitalized between measurements, body composition was compared pre- and post-hospitalization, with the results revealing significant decreases in body mass index, percent body fat, and PhA, and an increase in ECW/TBW.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Body composition is closely associated with hospitalization in patients undergoing MHD. Efforts to maintain euvolemic status and active interventions such as nutritional support and rehabilitation therapy may be essential to preserve a favorable body composition in this vulnerable population. <b>Geriatr Gerontol Int 2025; 25: 1389–1396</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 10","pages":"1389-1396"},"PeriodicalIF":2.5,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ggi.70167","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral small vessel disease and the lymphocyte-to-C-reactive protein ratio: Insights from a population study","authors":"Oscar H. Del Brutto,&nbsp;Robertino M. Mera,&nbsp;Denisse A. Rumbea,&nbsp;Emilio E. Arias,&nbsp;Kleber Arriaga,&nbsp;Víctor J. Del Brutto","doi":"10.1111/ggi.70168","DOIUrl":"10.1111/ggi.70168","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 10","pages":"1433-1435"},"PeriodicalIF":2.5,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Animal fluency as a specific indicator of aphasia in dementia screening: A retrospective study","authors":"Masaki Kamiya,&nbsp;Yuto Masuda,&nbsp;Aiko Osawa,&nbsp;Takako Yoshimura,&nbsp;Shinichiro Maeshima","doi":"10.1111/ggi.70164","DOIUrl":"10.1111/ggi.70164","url":null,"abstract":"","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 10","pages":"1431-1432"},"PeriodicalIF":2.5,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reciprocal links between nocturnal sleep and activities of daily living: A longitudinal study of midlife and older couples","authors":"Ziqiang Yu,&nbsp;Jinping Long,&nbsp;Weitao Lv,&nbsp;Jieyao Li,&nbsp;Dongliang Xu,&nbsp;Xiaoyan Shi,&nbsp;Yu Wang","doi":"10.1111/ggi.70159","DOIUrl":"10.1111/ggi.70159","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This study aimed to explore the bidirectional temporal relationships between nocturnal sleep (duration and quality) and activities of daily living (ADL) in midlife and older couples, while analyzing cross-spousal effects to inform collaborative health interventions for aging populations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The longitudinal study utilized three nationally representative waves of data (2015, 2018, 2020) from the China Health and Retirement Longitudinal Study (CHARLS). We included 2420 participants (1210 dyads). Generalized estimating equations (GEEs) and cross-lagged panel models were employed to examine temporal and cross-partner associations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean age of participants was 60.01 ± 6.95 years, with 9.01% exhibiting ADL limitations. GEE results revealed non-significant temporal effects on husbands' ADL changes (<i>z</i> = 1.741, <i>P</i> = 0.082), whereas wives demonstrated a significant decline in ADL function over time (<i>z</i> = 2.705, <i>P</i> = 0.007). In the sleep-duration model, wives' sleep duration directly predicted husbands' subsequent ADL (<i>β</i> = −0.058 and −0.044; <i>P</i> &lt; 0.05), and several indirect partner pathways were observed. In the sleep-quality model, husbands' poorer sleep quality directly predicted wives' later ADL (<i>β</i> = 0.077 and 0.052; <i>P</i> &lt; 0.05), while wives' poorer sleep quality influenced husbands' ADL indirectly via husbands' subsequent sleep. Eight hypothesized cross-spousal paths were supported at <i>P</i> &lt; 0.05.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>These findings highlight clinically significant bidirectional sleep–ADL dynamics in couples, emphasizing the need to treat spouses as interdependent health units. Incorporating brief partner sleep screening and dyadic sleep or caregiver supports into geriatric and rehabilitation pathways may help mitigate downstream functional decline. <b>Geriatr Gerontol Int 2025; 25: 1379–1388</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 10","pages":"1379-1388"},"PeriodicalIF":2.5,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social value of active seniors’ behavior in the inner beauty market: A systematic review","authors":"Myung Hyun Kim,&nbsp;Ki Han Kwon","doi":"10.1111/ggi.70157","DOIUrl":"10.1111/ggi.70157","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The world's aging population is rapidly increasing and this is one of the most important global challenges. This study examines active seniors' increased social activity, self-efficacy and social communication through inner beauty market behaviors, and proposes strategies to improve active seniors' quality of life, healthcare, economic independence and sustainability of inner beauty market behaviors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The study followed the preferred reporting items for systematic reviews and meta-analyses flowchart and utilized databases, such as PubMed, Scopus and Google Scholar, to research and analyze data until April 2025. Of the 996 studies, 38 studies were included in the systematic review based on inclusion and exclusion criteria.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of thirty-eight studies were included and systematically reviewed. Participation in the inner beauty market was linked to improved quality of life through health management, social engagement, and economic independence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Involvement in the inner beauty market enhances active seniors’ economic independence, social relationships, and holistic health. These findings support its role in promoting successful aging. <b>Geriatr Gerontol Int 2025; 25: 1295–1300</b>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"25 10","pages":"1295-1300"},"PeriodicalIF":2.5,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}