Frontiers in Human Neuroscience最新文献

{"title":"Functional connectivity in burnout syndrome: a resting-state EEG study.","authors":"Natalia Afek, Dmytro Harmatiuk, Magda Gawłowska, João Miguel Alves Ferreira, Krystyna Golonka, Sergii Tukaiev, Anton Popov, Tadeusz Marek","doi":"10.3389/fnhum.2025.1481760","DOIUrl":"10.3389/fnhum.2025.1481760","url":null,"abstract":"<p><p>Chronic occupational stress is associated with a pronounced decline in emotional and cognitive functioning. Studies on neural mechanisms indicate significant changes in brain activity and changed patterns of event-related potentials in burnout subjects. This study presents an analysis of brain functional connectivity in a resting state, thus providing a deeper understanding of the mechanisms accompanying burnout syndrome. The sample consists of 49 burnout employees and 49 controls, matched by age, gender and occupation (M_age = 36.15, SD = 8.10; 59 women, 39 men). Continuous dense-array EEG data were collected from a 256-channel EEG system. The difference in functional connectivity between burnout and control subjects was tested in the eyes-closed (EC) and eyes-open (EO) conditions using the resting-state paradigm. The results indicate significant differences in brain activity between the burnout and the control groups. The resting-state network of the burnout group is characterized by decreased functional connectivity in frontal and midline areas in the alpha3 sub-band (11-13 Hz) in an eyes-open condition. The most significant effect of decreased connectivity was observed in the right frontal brain area. For the first time, these analyses point to distinctive aspects of functional connectivity within the alpha3 sub-band in burnout syndrome. These findings provide insights into the neurobiological underpinnings of burnout syndrome and its associations with changed resting-state networks. The data on neural characteristics in burnout subjects may help to understand the mechanisms of decline in cognitive function and emotion regulation and to search for adequate methods of treatment.</p>","PeriodicalId":12536,"journal":{"name":"Frontiers in Human Neuroscience","volume":"19 ","pages":"1481760"},"PeriodicalIF":2.4,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11831065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143440399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurodiversity: post-cognitivist foundations of the 3E approach for educational inclusion of autistic students with technology.","authors":"Ronnie Videla, May Britt Aros, Francisco Parada, Leonie Kausel, Eduardo Sandoval-Obando, Daniela Jorquera, David Ibacache, Sebastián Maluenda, Pablo Rodríguez-Herrero, Carola Cerpa, María Jesús González, Marcelo Chávez, Paola Ramírez","doi":"10.3389/fnhum.2024.1493863","DOIUrl":"10.3389/fnhum.2024.1493863","url":null,"abstract":"<p><p>The concept of neurodiversity has gained strength in the last years to highlight the value of individual differences based on relevant variations in brain functioning. Inclusive education has embraced neurodiversity to promote a culture centered on valuing diversity, in response to clinical models based on deficits or disorders. This theoretical-critical article argues for the need to complement the current foundations of neurodiversity with post-cognitivist perspectives that reaffirm the brain-body-environment continuum, in order to enrich inclusive educational practices for autistic individuals. We begin by reviewing and discussing the concept of neurodiversity and neurocentric arguments in light of post-cognitivism. We then explore the potential of the 3E Cognition approach (embodied, enacted, and environmentally scaffolded) for addressing autism, aiming to provide a holistic understanding that contributes to the practical application of cognitive neuroscience findings in inclusive education. Finally, we present some guidelines and practical cases for creating inclusive educational environments based on digital technologies that enhance agency and sensory multimodality for autistic students.</p>","PeriodicalId":12536,"journal":{"name":"Frontiers in Human Neuroscience","volume":"18 ","pages":"1493863"},"PeriodicalIF":2.4,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11830657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential common targets of music therapy intervention in neuropsychiatric disorders: the prefrontal cortex-hippocampus -amygdala circuit (a review).","authors":"Yuqin Dan, Ying Xiong, Danghan Xu, Yuqi Wang, Meng Yin, Pengwei Sun, Yi Ding, Ziyun Feng, Peng Sun, Weili Xia, Gongchang Yu, Li Li","doi":"10.3389/fnhum.2025.1471433","DOIUrl":"10.3389/fnhum.2025.1471433","url":null,"abstract":"<p><p>As life becomes more stressful, neurological disorders, psychiatric disorders, and comorbidities of the two are becoming more and more of a concern. Multiple neuropsychiatric disorders share the same mental and somatic dysfunction and may involve common brain circuits and mechanistic targets. Music therapy, as an art form with proven efficacy, low cost and few side effects, is promoted for use in interventions for neuropsychiatric disorders. This may be closely related to the release of signaling molecules such as monoamine neurotransmitters, the glutamatergic system, the gut-microbiota-brain axis, pro-inflammatory cytokines and the endogenous opioid peptide system. However, fewer studies have mentioned the main targets of music to promote functional changes in brain regions. Therefore, this paper is a review of the mechanisms by which music therapy interacts with the prefrontal cortex-hippocampus-amygdala circuit through the aforementioned molecules. It is also hypothesized that glial cells, mitochondria and microRNAs are microscopic targets for musical intervention in neuropsychiatric disorders. The aim is to give new ideas for future research into the biological mechanisms of music therapy intervention in neuropsychiatric disorders.</p>","PeriodicalId":12536,"journal":{"name":"Frontiers in Human Neuroscience","volume":"19 ","pages":"1471433"},"PeriodicalIF":2.4,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832007/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143440402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review of parameter settings for galvanic vestibular stimulation in clinical applications.","authors":"Yishai Valter, Linda Vataksi, Aaron R Allred, Jeffrey R Hebert, Tad T Brunyé, Torin K Clark, Jorge Serrador, Abhishek Datta","doi":"10.3389/fnhum.2025.1518727","DOIUrl":"10.3389/fnhum.2025.1518727","url":null,"abstract":"<p><p>Galvanic Vestibular Stimulation (GVS) is a method of manipulating the vestibular system through non-invasive electrical current. Depending on how GVS is applied, it produces specific sensations related to vestibular mediated central pathways. The method has been tested for decades for both medical and non-medical applications and has demonstrated promise in treating a variety of disorders including peripheral vestibular conditions, central vestibular pathology due to neurodegenerative diseases, and post-stroke motor rehabilitation. As GVS continues to grow in popularity and applications, the field lacks clarity on appropriate stimulation parameters, despite their importance for safe and efficacious neuromodulation. This study aims to review the parameters used in various treatment applications while also providing a concise overview of the mechanisms underlying GVS thereby offering essential context and justification for the chosen parameters. We performed a literature search on the PubMed and Embase databases for clinical trials including the term \"galvanic vestibular stimulation.\" After removing duplicates, secondary analyses, and studies that did not use GVS for therapeutic purposes, we were left with 53 independent studies. We extracted the stimulation parameters used in each study and report them here. The results of this review suggest that while some stimulation parameters are relatively standardized for specific treatment indications, others lack universally accepted guidelines as the field of GVS continues to evolve. Based on our findings, we recommend that future GVS research include at least one sham condition, the use of individualized current intensity, and the comparison of multiple GVS parameters within the same trial.</p>","PeriodicalId":12536,"journal":{"name":"Frontiers in Human Neuroscience","volume":"19 ","pages":"1518727"},"PeriodicalIF":2.4,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11841469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroplasticity and functional reorganization of language in patients with arteriovenous malformations: insights from neuroimaging and clinical interventions.","authors":"Jialong Yuan, Hongchuan Niu, Chengxu Lei, Ruichen Xu, Yutong Liu, Kexin Yuan, Linru Zou, Shihao He, Yuanli Zhao","doi":"10.3389/fnhum.2025.1503864","DOIUrl":"10.3389/fnhum.2025.1503864","url":null,"abstract":"<p><p>Patients with arteriovenous malformations (AVMs) located in the functional area of speech often exhibit language dysfunction, and neuroplasticity allows the brain of some patients to regain speech through functional reorganization. Exploring the mechanism of AVMs-induced reorganization of language function is important for understanding neuroplasticity and improving clinical intervention strategies. This review systematically searched and analyzed the research literature in related fields in recent years, covering data from neuroimaging, functional magnetic resonance imaging (fMRI), and clinical case studies. By integrating these evidences, the phenomenon of functional reorganization within non-verbal functional areas and its influencing factors in patients with AVMs were assessed. It concluded that functional reorganization of language due to AVMs is a manifestation of a high degree of neurological plasticity and that understanding this process has important implications for neurosurgical planning and postoperative rehabilitation of patients. Future research should continue to explore the mechanisms of functional reorganization in the brain and work to develop new diagnostic tools and therapeutic approaches to improve the rate of recovery of language function in patients with AVMs.</p>","PeriodicalId":12536,"journal":{"name":"Frontiers in Human Neuroscience","volume":"19 ","pages":"1503864"},"PeriodicalIF":2.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11825511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Observing versus creating flowers: a review of relevance for art therapy.","authors":"Ephrat Huss, Mitsue Nagamine, Michele Zaccai","doi":"10.3389/fnhum.2025.1504057","DOIUrl":"10.3389/fnhum.2025.1504057","url":null,"abstract":"<p><p>This paper compares the embodied aesthetic experience of three types of images: photographed flowers, drawn flowers, and mandalas, summarizing data from three former comparative papers. The findings denote the strong embodied emotional connection of participants (changes in mood expressed in neural and physiological responses) to images of real flowers, as compared to the more cognitive reactions to drawings of flowers and cognitive stimulation of flower-like mandalas. These findings are discussed in terms of methodological relevance for art therapy and nature therapy. While it is known that flowers arouse positive emotions, this more nuanced comparison has interesting implications for visual art therapy, and for the therapeutic effects of nature photos, as opposed to drawn interpretations of nature.</p>","PeriodicalId":12536,"journal":{"name":"Frontiers in Human Neuroscience","volume":"19 ","pages":"1504057"},"PeriodicalIF":2.4,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11821929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in the movement phase condition and sensory inputs on temporal synchronization and continuation during bilateral foot-tapping tasks.","authors":"Atsuki Numata, Yasuo Terao, Kenichi Sugawara, Yoshikazu Ugawa, Toshiaki Furubayashi","doi":"10.3389/fnhum.2025.1518230","DOIUrl":"10.3389/fnhum.2025.1518230","url":null,"abstract":"<p><p>In the sensorimotor synchronization (synchronized and continuous tapping) task, subjects move their limbs in synchrony with an isochronous tone presented at various tempos and continue tapping at the same pace after the tones have ceased. We investigated the ability of bilateral lower limb motor control for performing this task as a crucial metric for examining motor coordination relevant to human locomotion, such as walking. Here, sensory information such as auditory and tactile inputs is considered to improve the accuracy of sensorimotor synchronization. In this study, we explored the change in tapping variability of rhythmic motor control of the bilateral lower limb with different movement phase conditions in the presence or absence of sensory information. Thirty-three healthy volunteers performed three types of foot-tapping tasks: synchronization-continuation (SC-tap), air-tapping (A-tap), and a combination of both (SCA-tap). Participants were instructed to tap the foot-switch (or perform a similar movement in the A-tap) in synchrony with the tones presented at fixed interstimulus intervals (ISIs) between 500 and 4,800 ms. Taps were performed with either unilateral foot or, in the case of bilateral movements, with both feet, either simultaneously (in-phase) or alternately for bilateral movements (antiphase). The synchronizing tapping error and the inter-tap interval (ITI) were evaluated. The coefficient of variation (CV) of ITI was significantly smaller for the antiphase condition than for the unilateral or in-phase conditions in the SC-tap and SCA-tap tasks. In addition, considering the timing of taps on both sides, the CV was significantly lower for antiphase only in the SC-tap task. The findings indicated that the antiphase condition exhibited superior temporal stability in repetitive lower limb movements. The findings also underscored the significance of tactile feedback from the soles of the feet when stability of rhythmic limb movements unpaced by the tones in antiphase movements was taken into consideration.</p>","PeriodicalId":12536,"journal":{"name":"Frontiers in Human Neuroscience","volume":"19 ","pages":"1518230"},"PeriodicalIF":2.4,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11821618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrical brain activations in preadolescents during a probabilistic reward-learning task reflect cognitive processes and behavior strategies.","authors":"Yu Sun Chung, Berry van den Berg, Kenneth C Roberts, Armen Bagdasarov, Marty G Woldorff, Michael S Gaffrey","doi":"10.3389/fnhum.2025.1460584","DOIUrl":"10.3389/fnhum.2025.1460584","url":null,"abstract":"<p><p>Both adults and children learn through feedback to associate environmental events and choices with reward, a process known as reinforcement learning (RL). However, tasks to assess RL-related neurocognitive processes in children have been limited. This study validated a child version of the Probabilistic Reward Learning task in preadolescents (8-12 years) while recording event-related-potential (ERPs), focusing on: (1) reward-feedback sensitivity (frontal Reward-related Positivity, RewP), (2) late attention-related responses to feedback (parietal P300), and (3) attentional shifting toward favored stimuli (N2pc). Behaviorally, as expected, preadolescents could learn stimulus-reward outcome associations, but with varying performance levels. Poor learners showed greater RewP amplitudes compared to good learners. Learning strategies (i.e., Win-Lose-Stay-Shift) were reflected by feedback-elicited P300 amplitudes. Lastly, attention shifted toward to-be-chosen stimuli, as evidenced by the N2pc, but not toward more highly rewarded stimuli as in adults. These findings provide novel insights into the neural processes underlying RL in preadolescents.</p>","PeriodicalId":12536,"journal":{"name":"Frontiers in Human Neuroscience","volume":"19 ","pages":"1460584"},"PeriodicalIF":2.4,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11821623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: EEG rhythms: decoding the evolutionary enigma of alpha rhythms in vertebrates.","authors":"Takashi Shibata, Kaoru Takakusaki","doi":"10.3389/fnhum.2025.1560294","DOIUrl":"10.3389/fnhum.2025.1560294","url":null,"abstract":"","PeriodicalId":12536,"journal":{"name":"Frontiers in Human Neuroscience","volume":"19 ","pages":"1560294"},"PeriodicalIF":2.4,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11821571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CBT and graded exercise therapy studies have proven that ME/CFS and long COVID are physical diseases, yet no one is aware of that.","authors":"Mark Vink, Alexandra Vink-Niese","doi":"10.3389/fnhum.2025.1495050","DOIUrl":"10.3389/fnhum.2025.1495050","url":null,"abstract":"","PeriodicalId":12536,"journal":{"name":"Frontiers in Human Neuroscience","volume":"19 ","pages":"1495050"},"PeriodicalIF":2.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11814198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143406954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}