Geburtshilfe Und Frauenheilkunde最新文献

{"title":"Clinical Performance of a Delphi Consensus and the sFlt-1/PlGF-ratio in Guiding Delivery Decisions in Early-Onset Preeclampsia Before 32 Weeks.","authors":"Lisa Antonia Lorenz-Meyer, Caroline Scheele, Lars Brodowski, Ulrich Pecks, Iris Dressler-Steinbach","doi":"10.1055/a-2902-9372","DOIUrl":"10.1055/a-2902-9372","url":null,"abstract":"<p><strong>Objective: </strong>A recent Delphi consensus defined organ-system-based parameters intended to reflect disease severity and delivery urgency in preeclampsia (PE) ≤ 32 weeks. This study evaluates the applicability of these parameters in a real-world cohort.</p><p><strong>Methods: </strong>In a retrospective cohort of 1928 women with suspected PE, 148 presented at ≤ 32 weeks, of whom 84 (56.8%) delivered at ≤ 32 weeks. Delivery indications documented in medical records were compared with organ-based Delphi criteria, and Likert scores were calculated. The association between the Delphi Score and the risk of PE-related delivery, as well as Delphi organ-system scores, mean maximal arterial blood pressure and the sFlt-1/PlGF-ratio were examined using regression analysis. ROC analyses and likelihood ratio tests were used to assess the Delphi score, sFlt-1/PlGF-ratio, and the combination of both to predict PE-related delivery.</p><p><strong>Results: </strong>The Delphi score was associated with an increased risk of PE-related deliveries ≤ 32+0 weeks (OR 1.27 per point, 95% CI 1.12-1.45), p < 0.001) but demonstrated limited predictive accuracy (AUC 0.699 (95% CI 0.612-0.787). Adding the sFlt-1/PlGF-ratio markedly improved model performance (χ ² from 16.3 to 72.4, p < 0.001; AUC 0.891, 95% CI 0.839-0.943). In the organ subscores, the uteroplacental and fetal Delphi criteria showed the strongest association (44% delivering ≤ 32 weeks vs. 9.4% delivering > 32 weeks). Severe hypertension (≥ 160/100 mmHg), not reflected in the Delphi criteria, led to 60.7% of deliveries.</p><p><strong>Conclusion: </strong>In this retrospective real-world cohort, the Delphi score showed limited applicability for guiding delivery decisions in PE ≤ 32 weeks. Incorporating broader hypertension thresholds and biomarkers may enhance decision-making approaches.</p>","PeriodicalId":12481,"journal":{"name":"Geburtshilfe Und Frauenheilkunde","volume":"86 10","pages":"925-935"},"PeriodicalIF":2.6,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13645445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149135817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Avoiding Overuse in German Gynaecology and Obstetrics - Adaptation of the Canadian \"Choosing Wisely\" Recommendations.","authors":"Philipp Scharli, Susanne Schüler-Toprak, Florian Ebner, Maren Goeckenjan, Diane Francoeur, Nikolaus Mezger, Annette Hasenburg","doi":"10.1055/a-2854-8087","DOIUrl":"10.1055/a-2854-8087","url":null,"abstract":"<p><p>Overuse in medicine refers to the provision of medical services that exceed what is necessary to meet patient needs and therefore result in more harm than benefit. Up to 30% of provided services can be classified as overuse. In several countries worldwide, including Canada, \"Choosing Wisely\" committees exist that issue recommendations to reduce overuse. In Germany, there are currently no recommendations for avoiding overuse in gynecology and obstetrics, which is why we adapted the recommendations of the Canadian \"Choosing Wisely\" initiative and discussed them in the context of the guidelines and directives applicable in Germany. Our article provides 13 concrete recommendations as well as practice-oriented suggestions for reducing overdiagnosis and overtreatment in gynaecology and obstetrics, thereby supporting the continuous and sustainable optimisation of patient care. Furthermore, reducing overuse in our field can help improve working conditions in healthcare professions and lower the ecological and economic costs of our healthcare system.</p>","PeriodicalId":12481,"journal":{"name":"Geburtshilfe Und Frauenheilkunde","volume":"86 7","pages":"630-637"},"PeriodicalIF":2.6,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13472742/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148760810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visiting Hours and Visitor Numbers During the Postnatal Period: The Basis for a Patient-Centred Visiting Policy on the Postnatal Ward.","authors":"Lukas Kristl, Stefan Hinterberger, Christina Kulle, Karin Lagger, Albrecht Gebhardt, Magdalena Annemarie Stöger, Magdalena Rosenkranz, Barbara Markota, Johannes Lermann","doi":"10.1055/a-2890-1486","DOIUrl":"https://doi.org/10.1055/a-2890-1486","url":null,"abstract":"<p><strong>Background: </strong>During the COVID-19 pandemic, many hospitals introduced restrictive visiting arrangements to reduce the risk of infection. This situation provided an opportunity to assess the acceptance of clearly defined visiting hours and visitor numbers on the postnatal ward. The aim of this study was to examine these regulations from the perspective of postpartum women and their support persons, and to identify implications for a sustainable long-term visiting policy.</p><p><strong>Materials and methods: </strong>A single-centre retrospective survey study enrolled women who had given birth at the Perinatal Centre of Klagenfurt am Wörthersee Hospital between October 2020 and December 2021. Data were collected 1-2 years postpartum using a purpose-designed, standardised and internally piloted questionnaire. The number of visitors, visiting hours and subjectively perceived effects on well-being, breastfeeding and the mother-child bond were assessed using a 5-point Likert scale. In addition, exploratory subgroup analyses were carried out on obstetric and sociodemographic parameters.</p><p><strong>Results: </strong>540 questionnaires were analysed (response rate 26.9%). The restriction on visitor numbers was viewed positively overall (postpartum women: mean 2.2; support persons: mean 2.4), whilst the time restrictions were viewed more critically (mean 3.0 and 3.2 respectively). Primiparous women, postpartum women who experienced complications, those who had undergone an unscheduled cesarean, and those whose newborns had been admitted to the neonatal intensive care unit rated the restrictions significantly more negatively. The reported effects on rest, well-being, breastfeeding and bonding were based solely on subjective assessments.</p><p><strong>Conclusion: </strong>Limited visitor numbers are generally viewed positively during the postnatal period, whereas strict time restrictions are viewed more critically. The findings support a structured yet flexible visiting policy that prioritises the involvement of close support persons and allows for exceptions in cases with difficult clinical courses. Given the retrospective design, the response rate and the exclusively subjective end points, causal statements can only be made to a limited extent.</p>","PeriodicalId":12481,"journal":{"name":"Geburtshilfe Und Frauenheilkunde","volume":"86 9","pages":"816-827"},"PeriodicalIF":2.6,"publicationDate":"2026-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13581414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148988966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal Malignancies Identified Through Non-invasive Prenatal Testing: A Systematic Review and Meta-Analysis.","authors":"Eduardo Teixeira, Gustavo Yano Callado, Daryane Rezzuto, Carolina Josué Vilella Waideman Puga, Henrique Provinciatto, Antonio Braga, Gabriele Tonni, Edward Araujo Júnior","doi":"10.1055/a-2900-2752","DOIUrl":"https://doi.org/10.1055/a-2900-2752","url":null,"abstract":"<p><strong>Objective: </strong>Non-invasive prenatal testing (NIPT) may incidentally reveal chromosomal abnormalities of maternal origin. Although specific chromosomal aberrations have been associated with maternal malignancy, reported risks vary widely. This meta-analysis aimed to quantify the magnitude and consistency of these associations.</p><p><strong>Methods: </strong>A systematic review and meta-analysis of observational studies reporting maternal malignancy among pregnant individuals with abnormal NIPT results was conducted. Odds ratios (ORs) with 95% confidence intervals (CIs) were pooled using a random-effects model. Risk of bias was assessed using the ROBINS-I tool.</p><p><strong>Results: </strong>Six studies met the inclusion criteria. Multiple chromosomal aberrations (MCA), although representing a minority of abnormal NIPT findings, accounted for a substantial proportion of confirmed maternal malignancies. MCA were strongly associated with cancer (OR 239.98; 95% CI 80.16-718.44; I ² = 0%). In studies that further characterized genomic patterns, complex gain-loss profiles were also associated with increased risk (OR 188.64; 95% CI 34.17-1041.51; I ² = 9.5%). Heterogeneity was low across analyses.</p><p><strong>Conclusion: </strong>Multiple chromosomal aberrations and complex gain-loss patterns on NIPT were strongly associated with maternal malignancy. These findings support the use of structured diagnostic pathways and targeted clinical evaluation when high-risk genomic patterns are identified.</p>","PeriodicalId":12481,"journal":{"name":"Geburtshilfe Und Frauenheilkunde","volume":"86 9","pages":"808-815"},"PeriodicalIF":2.6,"publicationDate":"2026-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13581417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148989008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutrition, Physical Activity and Other Health Aspects Before and During Pregnancy - Recommendations by the Nationwide \"Healthy Start Network\" (Netzwerk Gesund ins Leben) 2026.","authors":"Felizitas Alaze-Hagemann, Katharina Reiss, Michael Abou-Dakn, Karim Abu-Omar, Ute Alexy, Kirsten Beyer, Christina Breidenassel, Anna-Kristin Brettschneider, Monika Cremer, Regina Ensenauer, Marischa Fast, Nina Ferrari, Maria Flothkötter, Claudia Hellmers, Christine Joisten, Berthold Koletzko, Christel Rademacher, Ulrich Schiffner, Irene Somm, Melanie Speck, Ute Thyen, Anke Weißenborn, Achim Wöckel, Anna-Lena Zietlow, Constance Rybak","doi":"10.1055/a-2827-5905","DOIUrl":"10.1055/a-2827-5905","url":null,"abstract":"<p><p>The recommendations for action for the life phases of pregnancy and preconception of the nationwide Healthy Start Network (German <i>Netzwerk Gesund ins Leben</i> ) were revised and agreed onby an interdisciplinary scientific advisory board on the basis of current systematic reviews, meta-analyses, guidelines and other relevant literature. The 2026 version replaces the 2018 recommendations. The recommendations for action serve as evidence-based, application-oriented support for professionals for counselling before and during pregnancy and are supported by all relevant professional societies, professional associations and other institutions in Germany. They cover the topics of diversity-sensitive counselling, body weight before conception and weight development during pregnancy, energy and nutrient requirements as well as diet and beverages, including vegetarian/vegan nutrition and nutrition during pregnancy to prevent allergies in children. It also includes recommendations on the consumption of caffeine, alcohol, nicotine and, for the first time, cannabis. In addition, the nutrient supplements folic acid, iodine, iron, docosahexaenoic acid (DHA) and vitamin D are addressed. Special attention is paid to protection against foodborne infections, especially listeriosis and toxoplasmosis, and plant-based substitutes for animal-based foods is also taken into account. Another key topic is recommendations on physical activity before and during pregnancy. Aspects of oral and dental health, immunisation and the use of medicines before and during pregnancy as well as breastfeeding preparation are also covered.</p>","PeriodicalId":12481,"journal":{"name":"Geburtshilfe Und Frauenheilkunde","volume":"86 6","pages":"e60-e97"},"PeriodicalIF":2.6,"publicationDate":"2026-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148591272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insufficient Implementation of Recommendations in Pregnancies after Bariatric Surgery: Results from a Nationwide Real-World Study in Germany (PABS Study).","authors":"Ute Margaretha Schaefer-Graf, Ryna Fauzan, Babett Ramsauer, Christine Morfeld, Tanja Groten, Heidrun Sagmeister, Markus Schmidt, Friederike Weschenfelder","doi":"10.1055/a-2889-3406","DOIUrl":"10.1055/a-2889-3406","url":null,"abstract":"<p><p><b>Introduction</b> Bariatric metabolic surgery (MBS) is increasingly performed in women of reproductive age. Although MBS reduces obesity-related pregnancy complications, altered metabolism and nutritional deficiencies may adversely affect maternal and neonatal outcomes. This study evaluated (1) adherence to current guideline recommendations and (2) pregnancy outcomes in women after MBS in Germany. <b>Materials and Methods</b> In this multicenter cohort study, 410 pregnancies after MBS were collected between 2023 - 2025; 380 cases with complete data on BMI, MBS type, and birth weight were finally analyzed. Maternal characteristics, surgical details, preconceptional and prenatal care, and perinatal outcomes were descriptively assessed and compared with national reference data. <b>Results</b> Preconceptional BMI was 30.1 kg/m ² , 52% of the women were obese. Most common procedures were Roux-en-Y gastric bypass (RYGB; 58%) and sleeve gastrectomy (38%). Overall, 16% of the women conceived < 1 year after MBS, 27% after 1 - 2 years, and 57% after > 2 years. Before conception, 35% of the women neither received supplementation nor assessment for deficiencies (52%); similar rates were observed during pregnancy. Anemia occurred in 40%, particularly after RYGB. Oral glucose tolerance testing for gestational diabetes screening was used in 33% despite recommendations against it after MBS. Gestational diabetes was diagnosed in 23%. Rates of small and large for gestational age newborns were 20% and 6%, respectively; preterm birth occurred in 10% and C-section in 46%. <b>Conclusions</b> High rates of anemia and SGA highlight the need for specialized high-risk pregnancy care after MBS. Several guideline recommendations regarding surgery-to-conception interval, supplementation, and GDM screening were not consistently followed.</p>","PeriodicalId":12481,"journal":{"name":"Geburtshilfe Und Frauenheilkunde","volume":"86 10","pages":"907-914"},"PeriodicalIF":2.6,"publicationDate":"2026-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13645444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149135753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stillbirth Registration in Berlin - Insights from a Multicentre Online Register.","authors":"Amira Göpfrich, Maxi Stella Kniffka, Patrick Larscheid, Joachim Dudenhausen, Lars Hellmeyer, Klaus Vetter, Martina Ziegert, Thorsten Braun, Julia Callaghan, Josefine Königbauer","doi":"10.1055/a-2878-6952","DOIUrl":"https://doi.org/10.1055/a-2878-6952","url":null,"abstract":"<p><p><b>Introduction</b> In Germany, a stillbirth is defined as a birth without signs of life from the 24th week of pregnancy onwards or with a birth weight of ≥ 500 g. Stillbirths must be recorded at the registry office by means of a death certificate. It is often difficult to classify the specific cause in such cases. <b>Methods</b> In this retrospective, register-based observational study, the new online database <i>GeMoRe</i> is compared with all stillbirths reported to the Central Archive for Post-mortem Certificates in Berlin in 2024. The cases were then classified using the WHO-ICD-PM system to assess the accuracy (quality) and completeness (quantity) of the cases. <b>Results</b> <i>GeMoRe</i> recorded 128 stillbirths and the Central Archive for Death Certificates recorded 123 stillbirths; however, only 47 cases were found in both datasets. 18.8% of stillbirths recorded in the <i>GeMoRe</i> online register were attributed to a non-specific cause according to ICD-PM, compared with 70.7% of cases recorded via death certificates. <b>Discussion</b> The current method of recording death certificates often provides too few details for an ICD-PM classification in accordance with WHO recommendations. Furthermore, the number of stillbirths recorded in death certificates in Berlin may be underreported. A digital, Germany-wide register is required to enable high-quality data collection and to strengthen preventive measures.</p>","PeriodicalId":12481,"journal":{"name":"Geburtshilfe Und Frauenheilkunde","volume":"86 9","pages":"828-836"},"PeriodicalIF":2.6,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13581415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148989043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three Years of Co-Testing 2020-2022: Correlation of Diagnostic Colposcopy with Histology in Cases of Normal Cytology and Persistent High-Risk HPV.","authors":"Arjola Xhaja, André Ahr, Ilona Zeiser","doi":"10.1055/a-2871-3304","DOIUrl":"10.1055/a-2871-3304","url":null,"abstract":"<p><strong>Introduction: </strong>Since the introduction of organised cervical cancer screening, abnormal findings have been referred for diagnostic colposcopy in accordance with defined algorithms. The algorithms are primarily based on the HPV test results. A colposcopy is recommended even in cases where the cytology is normal but HPV persists. CIN2+ lesions are also detected in the process. <i>The aim of this study</i> is to investigate the causes of normal cytological results followed by CIN2+ lesions.</p><p><strong>Patients and methods: </strong>All cytological, HPV, and resultant histological test results from the primary screening, recorded in our database between 2020 and 2022, were analysed. The CIN2+ lesions with normal cytology were re-evaluated with regard to the quality of the cell material.</p><p><strong>Results: </strong>A total of 884201 preventive cytology tests and 5002 corresponding histology results from the years 2020-2022 were evaluated. In the normal groups I/II-a, 49 CIN2+ lesions were documented. After revision, 71% (35 cases) remained in group I/II-a. The revision resulted in 16% (8 cases) being reclassified into group 0, and in 12% (6 cases) showing minor discrepancies.</p><p><strong>Conclusion: </strong>Due to the persistence of high-risk HPV, CIN2+ lesions were diagnosed via colposcopy and biopsy despite normal cytology results. These lesions account for a small proportion of the total population. The main reason for the discrepancy was that the cell material was difficult to assess. In the majority of cases where discrepancies were found, but the cell material was otherwise easy to assess, dysplastic cells were absent. This shows that the real problem here lies in the pre-analytical stage. It is possible that the dysplastic areas may not be reached during the swab collection. Systematic reporting of specimen quality and a separate category for HPV-positive/cytologically unremarkable findings in MN III could improve diagnostic management.</p>","PeriodicalId":12481,"journal":{"name":"Geburtshilfe Und Frauenheilkunde","volume":"86 8","pages":"754-765"},"PeriodicalIF":2.6,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13467272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148724901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishing a Transgender Outpatient Clinic Within the Gynaecology Department: a Retrospective Analysis of the First Few Years.","authors":"Annelina Weiß, Jana Haussmann, Maren Goeckenjan","doi":"10.1055/a-2871-6787","DOIUrl":"10.1055/a-2871-6787","url":null,"abstract":"<p><strong>Introduction: </strong>Despite an increasing proportion of transgender individuals within the general population, robust epidemiological data on the medical care of transgender people in Germany remain limited. Data derived from a specialized transgender outpatient clinic provide insights into patient characteristics, diagnostic pathways, and treatment trajectories, and offer a basis for further development of needs-based, patient-centered care.</p><p><strong>Methods: </strong>This cross-sectional study includes retrospectively collected data from 199 transgender individuals who presented between 2020 and 2025 at the gynaecological endocrinology outpatient clinic of the University Hospital Dresden with a diagnosis or suspicion of gender incongruence (according to ICD-11).</p><p><strong>Results: </strong>The number of initial consultations increased continuously from 2020 to 2025. The majority of patients were young adults; initially, transfeminine individuals predominated, whereas in 2025, more transmasculine individuals presented. Gender-affirming hormone therapy was initiated (n = 111) or continued (n = 68) in 179 individuals. Fertility preservation measures prior to the initiation of hormone therapy were infrequently utilized. The median interval between first awareness of gender dysphoria and uptake of medical interventions was 11 years. Psychiatric comorbidities were reported by 53% of individuals, more frequently among trans women than trans men (trans women 60% vs. trans men 43%, p = 0.016).</p><p><strong>Conclusion: </strong>This study demonstrates the increasing demand for transgender-specific healthcare services. Transgender medicine should be more firmly integrated into standard care, with initiation of hormone therapy in specialized centres and continuation of treatment in outpatient settings appearing to be an appropriate model. A prospective, multicentre registry study is warranted to assess long-term outcomes. Currently, evidence in Germany is still largely based on retrospective and single-centre data. The present study confirms an increased prevalence of psychiatric comorbidities, underscoring the importance of structured psychological and/or psychiatric co-management as an integral component of interdisciplinary transgender care.</p>","PeriodicalId":12481,"journal":{"name":"Geburtshilfe Und Frauenheilkunde","volume":"86 7","pages":"649-659"},"PeriodicalIF":2.6,"publicationDate":"2026-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13372462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148455080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genital Herpes Simplex Virus (HSV) Infection During Pregnancy - Recommendations of the Working Group on Obstetrics and Prenatal Medicine (AGG - Section on Maternal Disorders).","authors":"Michael Oliver Schneider, Martin Enders, Daniela Huzly, Ulrich Pecks, Florian Faschingbauer, Karl Oliver Kagan, Sven Kehl","doi":"10.1055/a-2836-2552","DOIUrl":"10.1055/a-2836-2552","url":null,"abstract":"<p><strong>Aim: </strong>The AGG (Working Group for Obstetrics and Prenatal Diagnostics, Section Maternal Diseases) has issued these recommendations to improve the detection and management of genital herpes simplex virus (HSV) infections during pregnancy and the peripartal period.</p><p><strong>Methods: </strong>Members of the Task Force developed the recommendations and statements presented here using recently published literature. The recommendations were adopted after a consensus process by members of the working group.</p><p><strong>Recommendations: </strong>This article focuses on the epidemiology and pathophysiology of genital HSV infections during pregnancy and contains recommendations on maternal and fetal diagnosis, (suppressive) therapy, obstetric management, screening, and prevention.</p>","PeriodicalId":12481,"journal":{"name":"Geburtshilfe Und Frauenheilkunde","volume":"86 6","pages":"509-527"},"PeriodicalIF":2.6,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13287946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148316481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}