Frontiers in Nutrition最新文献

{"title":"Development and validation of a food photography atlas for portion size estimation of traditional Croatian dishes in adults.","authors":"Ivana Rumbak, Ana Ilić, Tea Knezović, Ana Jurčić, Martina Pavlić, Lidija Šoher, Daniela Čačić Kenjerić, Jasna Pucarin-Cvetković, Darja Sokolić","doi":"10.3389/fnut.2026.1956906","DOIUrl":"10.3389/fnut.2026.1956906","url":null,"abstract":"<p><strong>Background: </strong>Accurate portion size estimation is an important component of dietary assessment. Food photography atlases, which are among the most commonly used portion size measurement aids, are designed to take into account the cultural context and dietary patterns of the target population. Therefore, the aim of this study was to develop and validate food photography atlas of traditional Croatian dishes for adults.</p><p><strong>Methods: </strong>The 30 dishes were selected, in accordance with the gastronomic regions defined by Croatian National Tourist Board. The portion sizes were determined using data from the first Croatian national food consumption survey of the adult population, conducted in accordance with the EU Menu methodology. The photographs were validated by comparing them with the actual dishes served to 110 participants over a three-day period. Validity assessment included mean differences between actual and estimated portion sizes using the Wilcoxon signed-rank test, correlations between actual and estimated portion sizes, Bland- Altman limits of agreement, and quadratic weighted Cohen's kappa.</p><p><strong>Results: </strong>Of the 30 selected traditional dishes, no significant differences between actual and estimated portion sizes were observed for 46.7% of dishes, whereas portion sizes were underestimated for 30% and overestimated for 23.3%. For half of the dishes, at least 50% of the estimates were within ±10% of the differences between actual and estimated portion size. Spearman's correlation showed a strong association between actual and estimated portion size for all 30 dishes. Bland-Altman analysis demonstrated good agreement between actual and estimated portion sizes, with low systematic bias and narrow limits of agreement for single-unit and countable dishes. In 66.7% of dishes, more than half of the estimations were correct, while across all 30 dishes the proportion of distant estimations ranged from 0.0 to 31.0%. Quadratic weighted Cohen's kappa indicated almost perfect agreement for 29 dishes and substantial agreement for one dish.</p><p><strong>Conclusion: </strong>These results support the validity of the food photography atlas for estimating portion sizes of traditional dishes among adults in Croatia.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"13 ","pages":"1956906"},"PeriodicalIF":5.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13683142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149237579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of maternal gut microbiota in prenatal depression and offspring neurodevelopment.","authors":"Qiushuang Jia, Chengqian Diao, Shuai Liu, Huilin Yang, Xia Chen, Liemin Ruan, Zhongze Lou","doi":"10.3389/fnut.2026.1958794","DOIUrl":"10.3389/fnut.2026.1958794","url":null,"abstract":"<p><p>Prenatal depression is a prevalent complication during pregnancy that not only adversely affects maternal mental health and elevates the risk of postpartum depression but also has enduring implications for offspring development. Alterations in the host metabolome and gut microbiome have been linked to the onset and progression of depression; however, the biological mechanisms underlying the association between maternal mood disorders and fetal brain development remain inadequately understood. Recent studies have associated prenatal depression and psychological stress with alterations in the maternal gut microbiota, microbial metabolism, and immune signaling. However, most human evidence remains observational, and it remains unclear whether these microbial alterations precede depressive symptoms, arise as a consequence of depression or psychological stress, or act as intermediate factors within the maternal gut-brain axis. These findings offer novel strategies for the prevention and treatment of threats to maternal-fetal health. This article systematically reviews recent advancements in research concerning the \"microbiota-gut-brain\" axis in the context of maternal-fetal health. It investigates the roles and mechanisms of gut microbiota through preclinical and clinical studies, assesses the feasibility of potential therapeutic strategies, and suggests directions for future research. The aim is to provide a theoretical foundation for interventions targeting maternal-fetal health in cases of prenatal depression.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"13 ","pages":"1958794"},"PeriodicalIF":5.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13683943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149237594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetic sarcopenia in clinical practice: expert consensus and usability evaluation of a novel screening and diagnostic algorithm.","authors":"Alejandro Sanz-Paris, Francisco José Tarazona-Santabalbina, Juana Carretero Gómez, Daniel de Luis Román, José Manuel García-Almeida, Fernando Garrachón-Vallo, Juan José López-Gómez, Germán Guzmán-Rolo, Pedro Pablo García-Luna","doi":"10.3389/fnut.2026.1906664","DOIUrl":"10.3389/fnut.2026.1906664","url":null,"abstract":"<p><strong>Introduction: </strong>Recently, an expert panel developed an algorithm for the screening, diagnosis, and staging of diabetic sarcopenia, a clinically relevant condition in the progression of diabetes. Sarcopenia is associated with an increased risk of falls, physical disability, reduced quality of life, and increased mortality.</p><p><strong>Methods: </strong>A qualitative study, with quantitative aspects, was conducted to assess medical specialists' opinions on the applicability of the proposed algorithm. Data was collected using a questionnaire that included information relating to user experience, a usability questionnaire, a survey of healthcare professionals' opinions and a consensus form administered using the Delphi method.</p><p><strong>Results: </strong>The questionnaire was completed by 299 doctors (65.9% were women, mean age 39.1 (SD 8.5) years and with a mean of 10.4 (SD 8) years' experience). Most respondents indicated that screening for sarcopenia should be prioritised in patients with recent hospitalisations, major surgery, prolonged immobilisation and malignancies (Median 9, IQ0) and should be repeated annually in high-risk patients without a confirmed diagnosis (Median 8, IQ2). The algorithm was considered suitable for muscle assessment in people with diabetes. 90% of participants considered the tool to be easy to use, requiring no specialist staff (70%), and taking less than 7 min to apply (88%). For most respondents, use of the algorithm has changed the approach to decision-making regarding sarcopenia in patients with type 2 diabetes.</p><p><strong>Conclusion: </strong>The findings highlight the importance of systematic screening, diagnosis, and staging of diabetic sarcopenia, and demonstrate high levels of perceived applicability and usability of the proposed algorithm in routine clinical practice.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"13 ","pages":"1906664"},"PeriodicalIF":5.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13683586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149237608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Initial validation of the Hungarian Eating Disorder Examination Questionnaire Short (EDE-QS-H) in a sample of recreational athletes.","authors":"Réka Erika Kovács, Katarina Prnjak, Sohom Saha, İsmail İlbak, Szilvia Boros, Gusztáv József Tornóczky","doi":"10.3389/fnut.2026.1943893","DOIUrl":"10.3389/fnut.2026.1943893","url":null,"abstract":"<p><strong>Introduction: </strong>Eating disorders represent an important health concern among athletes, yet validated Hungarian screening tools remain limited. The present study aimed to translate, culturally adapt, and psychometrically validate the Hungarian version of the Eating Disorder Examination Questionnaire-Short (EDE-QS-H) in a sample of Hungarian athletes. A secondary aim was to examine the relationship between eating disorder psychopathology and multidimensional self-reported interoceptive awareness.</p><p><strong>Methods: </strong>A total of 205 recreational athletes recruited from two university settings (51.7% women; mean age = 21.8 ± 5.6 years) completed the Hungarian EDE-QS, the Disordered Eating Screen for Athletes-Hungarian version (DESA-6H), and the Hungarian Multidimensional Assessment of Interoceptive Awareness (MAIA). Confirmatory factor analysis (CFA) was performed using the robust weighted least squares estimator with mean and variance adjustment (WLSMV). Internal consistency was evaluated using Cronbach's <i>α</i> and McDonald's <i>ω</i>, whereas construct validity was assessed using Pearson correlation coefficients.</p><p><strong>Results: </strong>Sequential psychometric refinement resulted in a 10-item unidimensional model with improved model fit (<i>χ</i> ² = 82.77, df = 35, <i>χ</i> ²/df = 2.37, CFI = 0.987, TLI = 0.984, RMSEA = 0.082, SRMR = 0.066). The RMSEA was marginally above the conventional 0.08 criterion, whereas the remaining indices supported an acceptable measurement model. Standardized factor loadings ranged from 0.660 to 0.925, and the Average Variance Extracted was 0.671. The final version demonstrated excellent internal consistency (Cronbach's <i>α</i> = 0.902; McDonald's <i>ω</i> = 0.942). Construct validity was supported by a strong positive correlation with the DESA-6H (<i>r</i> = 0.643, <i>p</i> < 0.001), while associations with MAIA subscales were heterogeneous and generally small, indicating dimension-specific rather than broad relationships with self-reported interoceptive awareness.</p><p><strong>Conclusion: </strong>This initial validation provides evidence that the refined 10-item EDE-QS-H has promising factorial validity, excellent internal consistency, and construct-validity support in this university-based sample of Hungarian recreational athletes. The instrument may be useful as a brief research and preliminary screening measure of eating disorder psychopathology; however, diagnostic validity and broader clinical utility require evaluation in independent and clinical samples.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"13 ","pages":"1943893"},"PeriodicalIF":5.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13683691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149237616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: The interplay of lipoprotein(a), systemic inflammation, and dietary patterns in predicting cardiometabolic disease outcomes.","authors":"Keyang Zheng, Heng Zhang","doi":"10.3389/fnut.2026.1977546","DOIUrl":"10.3389/fnut.2026.1977546","url":null,"abstract":"","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"13 ","pages":"1977546"},"PeriodicalIF":5.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13683732/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149237534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of segmentation granularity on nutrient prediction from real-world food images.","authors":"Liam Hand, Guido Camps, Ricardo da Silva Torres, Albert Ali Salah","doi":"10.3389/fnut.2026.1927530","DOIUrl":"10.3389/fnut.2026.1927530","url":null,"abstract":"<p><p>Diet quality is central to preventing non-communicable diseases, yet traditional dietary assessment methods are burdensome and error-prone. Estimating nutrients directly from food images offers a scalable alternative, but most methods treat a meal as a single visual entity and estimate calories and mass more accurately than individual macronutrients. It has not yet been systematically evaluated whether decomposing a meal into its ingredients - predicting nutrients per ingredient and aggregating to the dish level - improves estimation. We compared three input representations for nutrient regression from overhead food images: direct regression from the original image, regression from binary food-region masks, and regression from fine-grained ingredient-level masks. To enable this, we annotated a 1,056-image subset of the Nutrition5K dataset with 2,922 ingredient-level segmentation masks across 40 categories, and used an identical regression model for all conditions. We also evaluated a realistic setting with automatically generated masks. Contrary to our hypothesis, finer segmentation did not improve overall performance: the unsegmented and binary food-region segmentation conditions performed comparably, while ingredient-level segmentation resulted in the highest error. Ingredient-level predictions preserved the relative balance of macronutrients well per ingredient, but errors in each ingredient's estimated nutrient quantities accumulated once aggregated to the dish level, leading to a general, though not strict, tendency toward worse performance as dish complexity increased. Ingredient-level regression stayed competitive for simpler dishes with visually separable ingredients, but struggled when ingredients were highly mixed. These findings indicate that the principal limitation of ingredient-level nutrient estimation is accurate quantity estimation rather than modeling of nutrient composition. Future work should prioritize explicit quantity cues, such as depth or volume, to complement ingredient-level decomposition. We release our annotations and code to support reproducible research.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"13 ","pages":"1927530"},"PeriodicalIF":5.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13683130/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149237545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biochemical and molecular mechanisms of probiotic action: current concepts and emerging therapeutic applications.","authors":"Alexey A Churin, Lyudmila O Sokolyanskaya, Anastasia P Lukina, Olga V Karnachuk","doi":"10.3389/fnut.2026.1964473","DOIUrl":"10.3389/fnut.2026.1964473","url":null,"abstract":"<p><p>Probiotic effects are mediated by a network of biochemical transformations and molecular signaling events that influence host physiology through local and systemic mechanisms. This review examines how probiotic microorganisms generate functional metabolites, including short-chain fatty acids, bile acid derivatives, and indole compounds, and how these molecules interact with host receptors and intracellular signaling pathways such as NF-κB, JAK/STAT, FXR, TGR5, AhR, and inflammasome-mediated signaling. In addition to metabolite-mediated signaling, probiotics may inhibit pathogens through organic acid production, bacteriocins, and quorum-quenching mechanisms, while also contributing to epithelial barrier integrity through modulation of tight-junction proteins and mucosal defenses. These interconnected pathways affect inflammation, metabolic regulation, host-microbe communication, and host defense against pathogens. The review further discusses pharmacomicrobiomic interactions, engineered probiotics, and emerging delivery technologies, highlighting the importance of strain specificity, host context, and microbiome composition in determining therapeutic outcomes. These findings underscore the importance of mechanistic frameworks for the rational development of targeted microbiome-based interventions.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"13 ","pages":"1964473"},"PeriodicalIF":5.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13684332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149237577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selenium supplementation for preventing cancer therapy-related toxicities: a systematic review and meta-analysis of clinical trials.","authors":"Chuyue Chang, Juncheng Wei, Mengfei Li, Tingyi Chang, Yakun Guo, Miao Jiang","doi":"10.3389/fnut.2026.1940806","DOIUrl":"10.3389/fnut.2026.1940806","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Trials of selenium for cancer supportive care vary in treatment context, formulation, dose, toxicity domain, and outcome definition. We evaluated the efficacy and safety of selenium supplementation for preventing or reducing cancer therapy-related toxicities.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;PubMed, Web of Science Core Collection, and the Cochrane Library were searched through June 30, 2026. Comparative clinical trials conducted during cancer therapy compared selenium with placebo, no selenium, observation, or selenium-free standard care. Two reviewers independently completed study selection, data extraction, outcome evaluation, and risk-of-bias assessment, with third-reviewer adjudication when required. Severe oral mucositis during head-and-neck radiotherapy or chemoradiotherapy was the primary outcome; broader pools were exploratory. Fixed- or random-effects analyses were supplemented by restricted maximum-likelihood models with Hartung-Knapp confidence intervals. Conference-abstract and derived-odds-ratio analyses were restricted to supplementary sensitivity analyses. Certainty was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework. The protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO; CRD420261448497).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Of 444 records, 333 unique records were screened. Forty-one of 49 sought reports were assessed in full text, and 31 reports representing 30 study groups were included; 17 groups contributed to the main analysis and 13 to supplementary evidence. Overall risk of bias was judged to be Some concerns for nine studies and High risk for eight. The four-study primary analysis (188 participants) was inconclusive (risk ratio [RR] 0.89, 95% confidence interval [CI] 0.50 to 1.56; &lt;i&gt;I&lt;/i&gt; &lt;sup&gt;2&lt;/sup&gt; 44.9%; very low certainty), as was the Hartung-Knapp analysis (RR 0.88, 95% CI 0.35 to 2.23). Five conventional exploratory confidence intervals crossed the null under Hartung-Knapp analyses. Across domains, the pooled estimate remained below the null (baseline RR 0.60, 95% CI 0.42 to 0.83; Hartung-Knapp RR 0.60, 95% CI 0.40 to 0.89; 11 studies), but heterogeneity was substantial and the certainty of evidence was very low.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Current evidence does not establish prevention of severe oral mucositis, but the consistent cross-domain direction and several domain-specific exploratory estimates suggest that selenium may attenuate selected treatment-related toxicities, particularly gastrointestinal and hematologic events, in appropriately selected settings. Because the majority of estimates are based on few, heterogeneous, and high-risk studies, these signals should inform targeted trials rather than routine universal supplementation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Systematic review registration: &lt;/strong&gt;This systematic review was registered with PROSPERO. Unique Identifier: CRD420261448497","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"13 ","pages":"1940806"},"PeriodicalIF":5.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13683797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149237585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cultural adaptation and validation of the SESMEB scale for assessing the influence of social media on the eating habits of adolescents in the city of Doboj, Bosnia and Herzegovina.","authors":"Dragana Stojisavljević, Marina Jotić Ivanović, Biljana Mijović, Maja Nikolić, Jelena Niškanović, Bojan Joksimović","doi":"10.3389/fnut.2026.1935743","DOIUrl":"10.3389/fnut.2026.1935743","url":null,"abstract":"<p><strong>Introduction: </strong>Marketing of foods high in fat, sugar and salt shapes the food preferences and intake of children and adolescents. The primary aim of this study was to culturally adapt and validate the Scale of Effects of Social Media on Eating Behavior (SESMEB) for assessing the influence of social media on the eating habits of adolescents in the Republic of Srpska, Bosnia and Herzegovina, and to examine whether this influence differs by sex, place of residence, nutritional status and school attended.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in six secondary schools in the city of Doboj in May 2023 and included 362 adolescents attending the third and fourth grades. The SESMEB scale was cross-culturally adapted into Serbian through forward and back-translation, expert panel review and pre-testing. Internal consistency was assessed by Cronbach's alpha and corrected item-total correlations, the factor structure by exploratory factor analysis, and test-retest reproducibility in a subsample of 14 respondents by the intraclass correlation coefficient (ICC). Group differences were tested by <i>t</i>-test and ANOVA.</p><p><strong>Results: </strong>The adapted scale showed good internal consistency (Cronbach's alpha = 0.865), with corrected item-total correlations from 0.346 to 0.638; the data were suitable for factor analysis (KMO = 0.857; Bartlett's test <i>χ</i> ² (153) = 2312.380; <i>p</i> < 0.001). Exploratory factor analysis identified three subscales accounting for 51.5% of the variance, which could not be clearly separated. Test-retest analysis showed no significant difference between administrations (<i>t</i> = 0.552; <i>p</i> = 0.591; ICC > 0.7). Mean scores for all 18 items denoted no perceived influence, with 55.0-76.8% of respondents reporting no effect on their food-related attitudes and practices. Girls scored higher than boys for following nutrition-related content (<i>p</i> < 0.05) and for the increase in the desire to eat (<i>p</i> = 0.048); differences also emerged by place of residence (<i>p</i> = 0.041) and school attended (<i>p</i> = 0.008; <i>p</i> = 0.004).</p><p><strong>Conclusion: </strong>Adopted version of the SESMEB scale is a reliable instrument for assessing the perceived effects of social media on adolescent eating behavior. Most respondents reported no such influence, even though this population is intensively exposed to digital marketing of energy-dense products, suggesting that self-report may underestimate the actual effect of that exposure.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"13 ","pages":"1935743"},"PeriodicalIF":5.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13683706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149237522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global research landscape and emerging frontiers of ultra-processed food intake and cardiometabolic health: a bibliometric and knowledge-mapping analysis (2015-2025).","authors":"Tianao Chen, Ping Ni, Minxin Li, Haijun Ma, Jin Dai, You Yu, Rui Yu","doi":"10.3389/fnut.2026.1916253","DOIUrl":"10.3389/fnut.2026.1916253","url":null,"abstract":"<p><strong>Objective: </strong>Bibliometric and visual analysis of research on ultra-processed food (UPF) intake and cardiometabolic health from 2015 to 2025.</p><p><strong>Methods: </strong>Publications from 2015 to 2025 were retrieved from the Web of Science Core Collection (WoSCC) and Scopus databases. Analyses were conducted using R software (bibliometrix package), VOSviewer, CiteSpace, and Origin 2018.</p><p><strong>Results: </strong>Scholarly output in this field demonstrated a continuous growth trajectory throughout the study period, with the steepest rise concentrated between 2020 and 2021. Brazil led in publication output, followed by the United States and China. The University of São Paulo ranked first among contributing institutions. <i>Nutrients</i>, <i>Public Health Nutrition</i>, and <i>Frontiers in Nutrition</i> were the most productive journals, while <i>Public Health Nutrition</i>, <i>Nutrients</i>, and the <i>American Journal of Clinical Nutrition</i> dominated the co-citation network. Prominent keywords included obesity, cardiovascular diseases, children, dietary patterns, and diabetes mellitus, reflecting the central themes of this field. Bibliometric analysis identified three key research hotspots: the association between UPF intake and cardiometabolic diseases (CMDs); the association between UPF consumption and early cardiometabolic impairment in children and adolescents; and mechanisms underlying food matrix disruption and food additive-mediated cardiometabolic dysregulation.</p><p><strong>Conclusion: </strong>Global research interest in the relationship between UPF intake and cardiometabolic health has grown substantially over the past decade. This study provides a comprehensive mapping of the current research landscape, key hotspots, and emerging frontiers in this field, offering a valuable reference for future investigations and public health interventions.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"13 ","pages":"1916253"},"PeriodicalIF":5.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13684074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149237573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}