Food Bioscience最新文献_第5页

The dietary flavonoid luteolin protects against cadmium-induced cerebral cortical injury in chickens via the endoplasmic reticulum stress-autophagy axis 饲粮中添加黄酮类木犀草素可通过内质网应激-自噬轴对镉诱导的鸡大脑皮质损伤起到保护作用

1区农林科学

Food Bioscience Pub Date : 2026-05-02 DOI: 10.1016/j.fbio.2026.109012

罗贤祖, Qianting Shi, Li Wang, Tao Wang, Yi Wang, Yonggang Ma, Xishuai Tong, Hui Zou, Jianhong Gu, Xuezhong Liu, Jianchun Bian, Zongping Liu, Yan Yuan

引用次数: 0

Comparative study on the changes of triacylglycerol lipolysis products and fatty acid bioaccessibility of four dietary lipids with varying degrees of unsaturation using in vitro digestion model 采用体外消化模型比较研究四种不同不饱和程度饲粮油脂的三酰甘油脂解产物及脂肪酸生物可及性的变化

1区农林科学

Food Bioscience Pub Date : 2026-05-01 DOI: 10.1016/j.fbio.2026.109015

Yanjun Guo, Zhan Ye, Wei Yang, Rui Xu, Yahui Gao, Yuanfa Liu

引用次数: 0

Metal-coordinated phlorizin derivatives: Structural characterization and α-glucosidase inhibitory activity 金属配位的根连素衍生物：结构表征和α-葡萄糖苷酶抑制活性

1区农林科学

Food Bioscience Pub Date : 2026-05-01 DOI: 10.1016/j.fbio.2026.108999

Mengqi Teng, Yuqing Zhang, Guorui Yang, Jiayu Sun, Haifang Xiao

引用次数: 0

An integrated genomic and phenotypic analysis insight into the comprehensive safety assessment of the potential probiotic Lactiplantibacillus plantarum TSP05 综合基因组和表型分析对潜在益生菌植物乳杆菌TSP05的综合安全性评估

1区农林科学

Food Bioscience Pub Date : 2026-04-07 DOI: 10.1016/j.fbio.2026.108858

Qineng Liu, Xinmei Guo, Jiayue Zhang, Bin Tang, Dong Peng, Jun Liu, Jianli Tang, Xuewei Jiang

引用次数: 0

EGCG–selenocysteine nanoparticles inducing ferroptosis and apoptosis in tumor cells egcg -硒代半胱氨酸纳米颗粒诱导肿瘤细胞铁下垂和凋亡

1区农林科学

Food Bioscience Pub Date : 2026-04-06 DOI: 10.1016/j.fbio.2026.108835

Ziqi Cao, Wu Qi, Yong Li, Xin Cong, Dejian Huang, Song Zhu, Shangwei Chen, Ruipeng Yu

引用次数: 0

Rapid screening of lipase inhibitors from Chrysanthemum indicum L. combining lipase-immobilized polypropylene hollow fibers with LC-MS and molecular networking 结合脂肪酶固定化聚丙烯中空纤维，LC-MS和分子网络技术快速筛选菊花脂肪酶抑制剂

1区农林科学

Food Bioscience Pub Date : 2026-04-05 DOI: 10.1016/j.fbio.2026.108833

Hui Zhang, Mengjia Xu, Felix Wambua Muema, Jun Ding, Mingquan Guo

引用次数: 0

Efficient solid state Maillard conjugation of ovalbumin and EGCG grafted β-glucan for NHDC liposome coating with enhanced phagocytic and anti-inflammatory activities 卵清蛋白和EGCG接枝β-葡聚糖的高效固体美拉德偶联用于NHDC脂质体包被，具有增强的吞噬和抗炎活性

1区农林科学

Food Bioscience Pub Date : 2026-04-03 DOI: 10.1016/j.fbio.2026.108823

Runyu Zhang, Songbai Liu

引用次数: 0

Bovine milk fat globule size-dependent membrane lipid heterogeneity underlies its differential effects on regulating fat digestion and neuron proliferation activity 牛乳脂肪球大小依赖的膜脂异质性是其调节脂肪消化和神经元增殖活性的差异作用的基础

1区农林科学

Food Bioscience Pub Date : 2026-04-02 DOI: 10.1016/j.fbio.2026.108812

Zhiyuan Ma, Jun Wang, Xueying Mao

引用次数: 0

Bifidobacterium pseudocatenulatum AL44 ameliorates Enterococcus faecium-induced lung inflammation through NLRP3 suppression along the gut-lung axis 假芽双歧杆菌AL44通过沿肠-肺轴抑制NLRP3改善粪肠球菌诱导的肺部炎症

IF 5.9 1区农林科学

Food Bioscience Pub Date : 2026-04-01 Epub Date: 2026-02-04 DOI: 10.1016/j.fbio.2026.108395

Shugang Li , Weiyun Zheng , Wudeng Wang , Xiaomeng Ren , Shuang Song , Chunqing Ai

{"title":"Bifidobacterium pseudocatenulatum AL44 ameliorates Enterococcus faecium-induced lung inflammation through NLRP3 suppression along the gut-lung axis","authors":"Shugang Li , Weiyun Zheng , Wudeng Wang , Xiaomeng Ren , Shuang Song , Chunqing Ai","doi":"10.1016/j.fbio.2026.108395","DOIUrl":"10.1016/j.fbio.2026.108395","url":null,"abstract":"<div><div>The gut microbiota plays an important role in regulating pulmonary inflammation via the gut-lung axis. In this study, <em>Bifidobacterium pseudocatenulatum</em> AL44, isolated from healthy infant feces, was evaluated in a mouse model of <em>Enterococcus faecium</em>-induced pneumonia. AL44 treatment markedly alleviated lung histopathological injury, oxidative stress, and inflammatory macrophage polarization. These protective effects were associated with modulation of the gut microbiota, characterized by the enrichment of beneficial taxa, enhanced intestinal barrier integrity, and reduced systemic endotoxin and inflammatory cytokine levels. Targeted serum metabolomics revealed significant alterations in amino acid metabolism, particularly within the glycine-serine-threonine-betaine pathway. <em>In vitro</em> studies showed that betaine, a key AL44-associated metabolite, suppressed lipopolysaccharide (LPS)-induced inflammatory response by inhibiting activation of NOD-like receptor family pyrin domain containing 3 (NLRP3) signaling pathway. Collectively, these results imply that AL44 mitigates pulmonary inflammation via modulation of the gut-lung axis, with betaine-mediated suppression of the NLRP3 signaling representing a potential pathway, supporting AL44 as a promising probiotic candidate for the management of pneumonia.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"78 ","pages":"Article 108395"},"PeriodicalIF":5.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146162047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced suppression of retrogradation and digestibility in waxy rice starch by engineered mutants of GtfC type 4,6-α-glucanotransferase from Geobacillus sp. Geobacillus sp. GtfC型4,6-α-葡聚糖转移酶工程突变体增强对糯米淀粉降解和消化率的抑制作用

IF 5.9 1区农林科学

Food Bioscience Pub Date : 2026-04-01 Epub Date: 2026-02-04 DOI: 10.1016/j.fbio.2026.108422

Dan Li , Yuwei Liu , Cuicui Duan , Fumin Ma , Byung-Hoo Lee , Xiaolei Li

{"title":"Enhanced suppression of retrogradation and digestibility in waxy rice starch by engineered mutants of GtfC type 4,6-α-glucanotransferase from Geobacillus sp.","authors":"Dan Li , Yuwei Liu , Cuicui Duan , Fumin Ma , Byung-Hoo Lee , Xiaolei Li","doi":"10.1016/j.fbio.2026.108422","DOIUrl":"10.1016/j.fbio.2026.108422","url":null,"abstract":"<div><div>GtfC type 4,6-α-glucanotransferase could induce short branches in starch by catalyzing inter- or inside-chain transglycosylation. To improve activity of wild-type (WT) GsGtfC from <em>Geobacillus</em> sp., 15 mutants were engineered by site-directed mutagenesis based on amino acid alignments, enzyme-substrate docking and dynamic simulation. At 2 U/g starch, five mutants with increased specific activity by 1.02–1.63-fold reduced molecular weight of starch from 8.85 × 10<sup>7</sup> to 4.18 × 10<sup>7</sup>–9.58 × 10<sup>6</sup> and increased DP ≤ 12 short branches from 33.18 to 35.77–43.65%, compared with WT. Retrogradation enthalpy of starch modified by K342V and WT reduced to 0.27 J/g and 0.69 J/g on the 14th day. RDS (rapidly digestible starch) of starch modified by K520A and WT decreased to 75.91% and 83.20%, and SDS (slowly digestible starch) increased to 22.88% and 11.85%. Glucose release from starch modified by K342V, K520A and D350N in a decreased order was significantly lower than that of WT from 120 to 360 min at small intestinal α-glucosidase level. Amino acid substitution strengthened enzyme-substrate affinity and stabilized critical hydrophobic interactions to enhance activity.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"78 ","pages":"Article 108422"},"PeriodicalIF":5.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146192454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0