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Fiziologicheskiĭ zhurnal最新文献

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[Lipid peroxidation and chromosome aberrations in mice after repeated effect of helium-oxygen respiratory mixture in hyperbaric conditions]. [高压条件下氦氧混合呼吸对小鼠脂质过氧化和染色体畸变的影响]。
Fiziologicheskiĭ zhurnal Pub Date : 1993-01-01
T P Shkurat, N P Miliutina, A E Nechepurenko, T A Kothcheeva, V M Sapozhnikov, E I Novikova, I V Timofeeva, E I Shimanskaia, B S Dashevskiĭ
{"title":"[Lipid peroxidation and chromosome aberrations in mice after repeated effect of helium-oxygen respiratory mixture in hyperbaric conditions].","authors":"T P Shkurat,&nbsp;N P Miliutina,&nbsp;A E Nechepurenko,&nbsp;T A Kothcheeva,&nbsp;V M Sapozhnikov,&nbsp;E I Novikova,&nbsp;I V Timofeeva,&nbsp;E I Shimanskaia,&nbsp;B S Dashevskiĭ","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Mice were exposed to helium-oxygen conditions (3.6 MPa, 5 sessions). Compression lasted for 6 h, isopression - 5 days, decompression - 18 h. The interval between sessions was 10 days. The present study has revealed that hyperbary increases the level of diene conjugates and shift bases in the erythrocyte membranes and plasma only after 1 and 3 sessions. Superoxide dismutase is suppressed after 3 and 5 sessions. Catalase activity remains unchanged. The effect of hyperbary on the induction of chromosome aberrations in bone marrow, cornea of the eye and germinal tissues has been studied. Bone marrow has been detected as more sensitive to hyperbary. Induction of aberrations in bone marrow cells has observed for 3 months.</p>","PeriodicalId":12337,"journal":{"name":"Fiziologicheskiĭ zhurnal","volume":"39 1","pages":"89-96"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19321341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Changes in the functional state of lysosomal apparatus of neutrophilic leukocytes in rabbits caused by immobilization with adrenoblockers]. [肾上腺素阻断剂固定兔中性粒细胞溶酶体功能状态的变化]。
Fiziologicheskiĭ zhurnal Pub Date : 1993-01-01
N V Lunina, S V Vovk
{"title":"[Changes in the functional state of lysosomal apparatus of neutrophilic leukocytes in rabbits caused by immobilization with adrenoblockers].","authors":"N V Lunina,&nbsp;S V Vovk","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The experiments were carried out on rabbits aimed at elucidating the significance of alpha- and beta-adrenoreceptors in the reactions of release of lysosomal enzymes of peripheral blood neutrophils in response to the immobilization action. In the process of formation of stress-syndrome under the influence of uninfectious stressor it is noted that alpha- and beta-adrenoceptors take part in the regulation of the activity of the lysosomal apparatus of neutrophil leukocytes and in release of the lysosomal enzymes participating in the regulation of haemostasis through the Hageman-factor.</p>","PeriodicalId":12337,"journal":{"name":"Fiziologicheskiĭ zhurnal","volume":"39 1","pages":"29-35"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19094802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Circadian rhythm of intestinal glucose absorption in fasting and fed rats]. [禁食和喂养大鼠肠道葡萄糖吸收的昼夜节律]。
Fiziologicheskiĭ zhurnal Pub Date : 1993-01-01
M I Voloshenovich, M A Labusheva, A M Ugolev, V P Pishak
{"title":"[Circadian rhythm of intestinal glucose absorption in fasting and fed rats].","authors":"M I Voloshenovich,&nbsp;M A Labusheva,&nbsp;A M Ugolev,&nbsp;V P Pishak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Under conditions of chronic experiment the circadian cycle of glucose transport was determined. An isolated proximal area of the small intestine was perfused by glucose, fructose, medical bile and Ringer's solutions in various intervals of the 24 hour period. The circadian cycle of glucose absorption is disturbed in the fasting rats. Various substrates differently alter their amplitude and acro-phase of absorption. Ringer's solution perfusion shifts the acro-phase absorption to evening time, while that of fructose occurs during day time and that of bile takes place at night. The circadian cycle of the fed rats is less subject to shifts. Fasting is a powerful exogenous factor causing structural changes in the small intestine and altering the circadian cycle of glucose absorption.</p>","PeriodicalId":12337,"journal":{"name":"Fiziologicheskiĭ zhurnal","volume":"39 1","pages":"107-12"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19322061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Protective effect of vitamin E in total ischemia of isolated organs in rats]. [维生素E对大鼠离体器官全缺血的保护作用]。
Fiziologicheskiĭ zhurnal Pub Date : 1993-01-01
A V Paranich, O S Iukhnik
{"title":"[Protective effect of vitamin E in total ischemia of isolated organs in rats].","authors":"A V Paranich,&nbsp;O S Iukhnik","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The content of lipid peroxidation (LPO) products and fat-soluble vitamins in the isolated liver and heart of rats total ischemia of organs has been studied. Ischemia shifts the antioxidative balance towards LPO and formation of vitamin E metabolites of different destruction degree. It is shown that under such conditions the reactions of initial tocopherol reduction are possible in the case of preliminary introduction of physiological doses of vitamin E into the organism. In the myocardium the protective effect of tocopherol is much higher than in the liver.</p>","PeriodicalId":12337,"journal":{"name":"Fiziologicheskiĭ zhurnal","volume":"39 1","pages":"97-101"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19322540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Assessment of reactivity of heart rhythm regulatory system in response to physical exertion]. [对体力消耗时心律调节系统反应性的评估]。
Fiziologicheskiĭ zhurnal Pub Date : 1993-01-01
G V Korobeĭnikov
{"title":"[Assessment of reactivity of heart rhythm regulatory system in response to physical exertion].","authors":"G V Korobeĭnikov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The study involving 35 sportsmen and 35 non-sportsmen was undertaken to assess the reactivity of human heart sinus node in response to physical workload depending on the initial state of the blood circulation system. It is found that sportsmen have predominantly a hyperreactive type and non-sportsmen--a hyporeactive type of sinus node reactivity to workloads. Moreover, the reactivity of heart sinus node in response to physical workload depends considerably on the initial state of the system of blood circulation regulation at a relative rest. The regression equation for assessment of heart sinus node reactivity to workload is proposed.</p>","PeriodicalId":12337,"journal":{"name":"Fiziologicheskiĭ zhurnal","volume":"39 1","pages":"10-4"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19322059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Changes in the neuroendocrine and immune state of adaptational homeostasis in normal pregnancy]. 【正常妊娠期神经内分泌和免疫状态的适应性稳态变化】。
Fiziologicheskiĭ zhurnal Pub Date : 1993-01-01
Iu A Grinevich, E V Kokhanevich, L G Iugrinova, I F Labunets, I I Patskan, N I Tsip
{"title":"[Changes in the neuroendocrine and immune state of adaptational homeostasis in normal pregnancy].","authors":"Iu A Grinevich,&nbsp;E V Kokhanevich,&nbsp;L G Iugrinova,&nbsp;I F Labunets,&nbsp;I I Patskan,&nbsp;N I Tsip","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>43 women with physiologically proceeding pregnancy have been examined during 1st, 2nd and 3d terms. The control group consists of 28 practically healthy non-pregnant women. It is stated that during pregnancy essential changes in the function of endocrine glands of mother take place. the appearance of placenta, a new gland of internal secretion, producing choriogonadotropin (CG) as well as the great amount of other hormones of the steroid and protein nature causes essential changes in the regulatory mechanisms underlying the physiological activity of internal secretion glands in mother. The development and early functioning of the internal secretion glands of a fetus promote the hormonal shifts. With the pregnancy development the number of estrogen increases hundred times, relative to their production in non-pregnant women secretion of progesterone and prolactin increase ten times. The functional activity of anterior lobe of the hypophysis, manifesting itself in hypersecretion of adrenocorticotropic hormone inhibition of follicule-stimulating hormone production changes as well. Changes in the functional state of the adrenal gland cortex: cortisole secretion is high are found.</p>","PeriodicalId":12337,"journal":{"name":"Fiziologicheskiĭ zhurnal","volume":"39 1","pages":"61-7"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19321338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The determination of T-lymphocyte antigenic markers in the serum of patients with atopic dermatitis]. [特应性皮炎患者血清t淋巴细胞抗原标记物的测定]。
Fiziologicheskiĭ zhurnal Pub Date : 1993-01-01
I A Bezvershenko, M G Boĭko, L D Kaliuzhnaia
{"title":"[The determination of T-lymphocyte antigenic markers in the serum of patients with atopic dermatitis].","authors":"I A Bezvershenko,&nbsp;M G Boĭko,&nbsp;L D Kaliuzhnaia","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The euglobulin fraction of serum of the patients with atopic dermatitis was studied using monoclonal antibodies OKT3, OKT8 and OKT10 in assay system including secondary 125J labeled anti-mouse IgG antibodies. It was shown that CD3, CD8 and CD38 T-cell marker antigens shed from the T-cell surface could be found in euglobulin fraction of serum patients. The patients with atopic dermatitis successfully treated with immunomodulator vilosen were selected and their serums obtained before and after treatment were investigated. The treatment resulted in the increase of CD8, CD3 determinants and a decrease of antigens determined by OKT10 antibodies (CD38). It is supposed that an increase of CD3 and CD8 determinants is caused by stimulation of T-lymphocyte proliferation and suppressor cell function by vilosen. Since CD38 marker is predominantly on the surface of immature and activated T-cells, which do not occur in circulating blood, it can be supposed that decrease of CD38 in the euglobulin fraction of serum reflects a shedding of these determinants from T-cells of thymus and peripheral lymphoid organs.</p>","PeriodicalId":12337,"journal":{"name":"Fiziologicheskiĭ zhurnal","volume":"39 1","pages":"67-72"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19321335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Restoration of peptidergic regulation in the kidney by exogenous polypeptide substances of renal origin]. [肾脏来源的外源性多肽物质对肾脏肽能调节的恢复]。
Fiziologicheskiĭ zhurnal Pub Date : 1992-11-01
I P Kaĭdashev
{"title":"[Restoration of peptidergic regulation in the kidney by exogenous polypeptide substances of renal origin].","authors":"I P Kaĭdashev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Investigations, performed by high-effective liquid chromatography method have shown changes in the chromatographic spectrum of polypeptides, extracted from the cortex of the kidneys of rats with experimental pathology (autoimmune Haymann's nephritis). Injection of exogenous polypeptides substances extracted from kidney tissues caused normalization of the exogenous polypeptide substances in the kidneys of the experimental animals. A conclusion is made on the regulatory influence of renal exogenous polypeptides in terms of conception of the peptidergic regulation system.</p>","PeriodicalId":12337,"journal":{"name":"Fiziologicheskiĭ zhurnal","volume":"38 6","pages":"106-9"},"PeriodicalIF":0.0,"publicationDate":"1992-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12513596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Interactions of the macrocellular neurosecretory system of the hypothalamus and the endocrine pancreas of rats in adaptation to hypoxia]. [大鼠下丘脑大细胞神经分泌系统与内分泌胰腺在适应缺氧中的相互作用]。
Fiziologicheskiĭ zhurnal Pub Date : 1992-11-01
Iu M Kolesnyk, Iu M Orestenko, A V Abramov
{"title":"[Interactions of the macrocellular neurosecretory system of the hypothalamus and the endocrine pancreas of rats in adaptation to hypoxia].","authors":"Iu M Kolesnyk,&nbsp;Iu M Orestenko,&nbsp;A V Abramov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Daily hypoxia (6 h, 6000 m) changed the functional state of endocrine pancrease of male and female Wistar rats. The actions of hypoxia on functional state of supraoptic (SO) and paraventricular (PV) nuclei of hypothalamus and islet cells of endocrine pancreas were examined using immunocytochemical, histochemical, morphometric and radioimmunoassay methods. Increase of insulin biosynthesis in beta cells and glucagon secretion of alpha cells, and decrease of the somatostatin contents in delta cells of pancrease islets have been investigated. The functional activity of vasopressinergic magnocellular subnucleus of PV increased, but that of SO decreased with reduction of vasopressin blood concentration at the same time. The functional state of oxytocin synthesis subdivisions of PV and SO were sex dependent, but the oxytocin contents in median eminence increased.</p>","PeriodicalId":12337,"journal":{"name":"Fiziologicheskiĭ zhurnal","volume":"38 6","pages":"30-6"},"PeriodicalIF":0.0,"publicationDate":"1992-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12536663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Role of globus pallidus in mechanisms of antiepileptic caudate- cortical effects]. [苍白球在抗癫痫的尾状-皮质作用机制中的作用]。
Fiziologicheskiĭ zhurnal Pub Date : 1992-11-01
R F Makulkin, S A Novytskyĭ, T V Korniienko
{"title":"[Role of globus pallidus in mechanisms of antiepileptic caudate- cortical effects].","authors":"R F Makulkin,&nbsp;S A Novytskyĭ,&nbsp;T V Korniienko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The experiments on rats have shown that striatal electrostimulation influences inhibiting cortex epileptic activity decrease under conditions of globus pallidus destruction. Besides, it is noted that globus pallidus lesion exerts a pronounced antiepileptic effect on development of the neocortical epileptic activity complexes. Globus pallidus stimulation enhanced the neocortex interictal seizure activity and transformed it to ictal discharges. The results are discussed in terms of the role of pale globe in mechanisms of caudate inhibitory action on neocortex epileptic activity.</p>","PeriodicalId":12337,"journal":{"name":"Fiziologicheskiĭ zhurnal","volume":"38 6","pages":"3-9"},"PeriodicalIF":0.0,"publicationDate":"1992-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12514226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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