[Restoration of peptidergic regulation in the kidney by exogenous polypeptide substances of renal origin].

Abstract

Investigations, performed by high-effective liquid chromatography method have shown changes in the chromatographic spectrum of polypeptides, extracted from the cortex of the kidneys of rats with experimental pathology (autoimmune Haymann's nephritis). Injection of exogenous polypeptides substances extracted from kidney tissues caused normalization of the exogenous polypeptide substances in the kidneys of the experimental animals. A conclusion is made on the regulatory influence of renal exogenous polypeptides in terms of conception of the peptidergic regulation system.