Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment最新文献

{"title":"Rapid determination of volatile benzene derivatives and chlorobenzenes in goat's milk by HS-SPME-GC-MS/MS.","authors":"Jingyin Qin, Kaixuan Tong, Qiaoying Chang, Yujie Xie, Xingqiang Wu, Chunlin Fan, Hui Chen","doi":"10.1080/19440049.2024.2400224","DOIUrl":"10.1080/19440049.2024.2400224","url":null,"abstract":"<p><p>A method for the determination of eight benzenes (BTEXs) and twelve chlorobenzenes (CBs) in goat's milk by headspace solid-phase microextraction-gas chromatography-mass spectrometry (HS-SPME-GC-MS/MS) was developed. The study investigated the impact of various factors such as extraction fiber type, salt amount, equilibrium conditions, and desorption conditions on the outcomes. Target analytes were separated on a DB-HeavyWAX column and quantified using the external standard method. The results showed that the target compounds had a good linear relationship in the range of 0.01 ∼ 50 μg/L (<i>R</i>² > 0.997), the limit of detection (LOD) was 0.003 ∼ 0.150 μg/L, and the limit of quantification (LOQ) was 0.01 ∼ 0.50 μg/L. The average recoveries were 82%-116% and the relative standard deviation (RSD) was 0.8%-17.3% under the three addition levels of 1×, 2×, and 10 × LOQ. In a survey of twenty goat's milk samples, only ethylbenzene, xylenes, cumene, chlorobenzene, and 1,4-dichlorobenzene were detected at levels exceeding their respective limits of quantification. The method was evaluated using two ecological scales (Eco-Scale), GAPI and AGREEN, to verify its environmental friendliness and applicability. This method is simple, green, and efficient, which provides a certain theoretical basis for the production and quality safety evaluation of dairy products.</p>","PeriodicalId":12295,"journal":{"name":"Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment","volume":" ","pages":"1480-1497"},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142139705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of bisphenol S (BPS) in packaged fish, meat, cheese, and price labels on their corresponding packages.","authors":"Xu-Liang Cao, Wen-Hsuan Fu, Svetlana Popovic","doi":"10.1080/19440049.2024.2394170","DOIUrl":"10.1080/19440049.2024.2394170","url":null,"abstract":"<p><p>As an alternative to bisphenol A (BPA), bisphenol S (BPS) has been used as an ink developer in thermal paper products including price labels on food packaging which have been suggested as the sources of BPS found at high levels in packaged fish samples. BPS in the printed price labels glued onto the outside of plastic film could migrate indirectly from the printed surface through the paper, adhesive and film into the food. In order to investigate if price labels could also be the sources of BPS detected in the meat samples in our previous studies, meat and other food samples packaged under different conditions were collected, and BPS in these samples together with the price labels on the corresponding packaging were extracted with solvent followed by solid phase extraction and stable isotope dilution LC-MS/MS analysis. BPS was detected at very high levels (161.7-222.4 µg/cm²) in all the five sticker type of price labels, indicating BPS being the dominant if not the sole ink developer. BPS was also detected in all the 26 continuous roll type of price labels but at very low levels (0.017-18 ng/cm²), indicating that the dominant ink developer is likely one of the other alternatives, rather than BPS. Despite BPS being detected in all price labels on packaging of fish, meat, and cheese samples, BPS was not detected or detected in only a few fish, meat, and cheese samples at levels considerably lower than the current EU specific migration limit (SML) of 50 ng/g food for BPS authorised under Regulation (EU) 10/2011.</p>","PeriodicalId":12295,"journal":{"name":"Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment","volume":" ","pages":"1509-1515"},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142035608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aflatoxin M₁ levels in urine and breast milk of lactating mothers in Kuala Lumpur, Malaysia.","authors":"Alyaa Izzati Aminuddin, Rosita Jamaluddin, Mohd Redzwan Sabran, Nurul Husna Mohd Shukri","doi":"10.1080/19440049.2024.2386462","DOIUrl":"10.1080/19440049.2024.2386462","url":null,"abstract":"<p><p>Aflatoxins are carcinogens that can contaminate food and affect various body organs especially liver and kidney. When consumed, aflatoxin B₁ (AFB₁) is partially metabolised into aflatoxin M₁ (AFM₁), which is excreted in the urine. Breast milk may also contain AFM₁ due to maternal dietary intake from contaminated food. This cross-sectional study aimed to determine the levels of AFM₁ in both urine and breast milk among breastfeeding mothers (<i>n</i> = 256). The mother's demographic information was collected during recruitment. Mothers were then scheduled for an appointment to provide a morning urine sample along with five to ten mL samples of breast milk. AFM₁ levels in both samples were analysed using an enzyme-linked immunosorbent assay (ELISA). Spearman's rho and Chi-square were used to determine the associations between mean levels of AFM₁ in urine and breast milk. Findings show 68.0% of urine samples were contaminated with AFM1 (mean levels = 0.08 ± 0.04 ng/mL), while 14.8% of breast milk samples had AFM₁ (mean levels = 5.94 ± 1.81 ng/kg). Urine AFM₁ levels were not significantly associated with AFM₁ levels in breast milk (<i>p</i> > 0.05). This study can act as a baseline for future research examining long-term aflatoxin exposure among both mothers and infants.</p>","PeriodicalId":12295,"journal":{"name":"Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment","volume":" ","pages":"1360-1367"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141874590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dissipation kinetics and risk assessment of residues of combination product of two fungicides, fluxapyroxad, and pyraclostrobin in cumin.","authors":"Kaushikkumar D Parmar, Nidhi N Chaudhary, Ravi L Kalasariya, Suchi Chawla, Saurabh C Thakor, Chirag J Patel, Dasharathlal S Patel, Laljibhai F Akbari, Girdhari Lal Kumawat","doi":"10.1080/19440049.2024.2387194","DOIUrl":"10.1080/19440049.2024.2387194","url":null,"abstract":"<p><p>Supervised field trial studies were conducted to understand dissipation kinetics and harvest time residues of a combination product of fluxapyroxad and pyraclostrobin in cumin plant/leaves and seeds at different locations in India. The results showed initial accumulation of fluxapyroxad at the levels of 15.4 and 20.2 mg kg^-1 and pyraclostrobin at the level of 21.2 and 33.4 mg kg^-1 in cumin leaves/plant in Anand, Gujarat. Fluxapyroxad and pyraclostrobin followed zero-order and first-order dissipation kinetics in cumin plant/leaves samples respectively. The residues translocated to cumin seeds. As the hazard quotient (HQ) was <1 in all cases consumer health risk may be negligible.</p>","PeriodicalId":12295,"journal":{"name":"Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment","volume":" ","pages":"1288-1301"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141893230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The occurrence and biological control of zearalenone in cereals and cereal-based feedstuffs: a review.","authors":"Hongmin Zhen, Yumeng Hu, Ke Xiong, Mengmeng Li, Wen Jin","doi":"10.1080/19440049.2024.2385713","DOIUrl":"10.1080/19440049.2024.2385713","url":null,"abstract":"<p><p>Zearalenone, a prominent mycotoxin produced by <i>Fusarium</i> spp., ubiquitously contaminates cereal grains and animal feedstuffs. The thermal stability of zearalenone creates serious obstacles for traditional removal methods, which may introduce new safety issues, or reducing nutritional quality. In contrast, biological technologies provide appealing benefits such as easy to apply and effective, with low toxicity byproducts. Thus, this review aims to describe the occurrence of zearalenone in cereals and cereal-based feedstuffs in the recent 5 years, outline the rules and regulations regarding zearalenone in the major countries, and discuss the recent developments of biological methods for controlling zearalenone in cereals and cereal-based feedstuffs. In addition, this article also reviews the application and the development trend of biological strategies for removal zearalenone in cereals and cereal-based feedstuffs.</p>","PeriodicalId":12295,"journal":{"name":"Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment","volume":" ","pages":"1344-1359"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141893231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dissipation and dietary risk assessment of fluoxapiprolin (and its metabolites) residues in cucumber and tomato samples under field conditions.","authors":"Nitesh S Litoriya, Ravi L Kalasariya, Kaushik D Parmar, Jignesh H Patel, Sunny H Patel, Nidhi N Chaudhary, Nirmal R Chauhan, Suchi Chawla, Paresh G Shah","doi":"10.1080/19440049.2024.2380918","DOIUrl":"10.1080/19440049.2024.2380918","url":null,"abstract":"<p><p>The present study was undertaken to understand the dissipation behaviour/kinetics of fluoxapiprolin and its metabolites in cucumber and tomato under field conditions. A QuEChERS based extraction method followed by liquid chromatography coupled to mass spectrometry (LC-MS/MS) analysis showed that all method validation parameters were within the acceptable range as per international standards with a limit of quantitation (LOQ) of 0.01 mg kg^-1 for all analytes. As significant matrix effects were observed with a few metabolites, matrix matched standards were used for the whole study. Residues of fluoxapiprolin in cucumber at standard dose were steady from 0 to 3 day after application and were below LOQ on the 5^th day after application. In cucumber fruit at double dose and in tomato at both the doses the residues followed second-order kinetics and were respectively ≤ LOQ from days 7 and 14 onwards. Pre-harvest intervals (PHI) of 5 days and 14 days are proposed for cucumber and tomato fruits respectively. All the metabolites were ≤ LOQ from day 0 in all the matrices. The consumer risk, assessed as Hazard Quotient (HQ), showed that HQ was ≤1 in all the cases. The results of the present study and earlier studies on other similar fungicides suggest that the use of fluoxapiprolin in cucumber and tomato fruits may not pose health or environmental hazards provided that good agricultural practices are followed and the proposed waiting period is observed. The data from the present study can be used by regulatory bodies in establishing maximum residue limits.</p>","PeriodicalId":12295,"journal":{"name":"Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment","volume":" ","pages":"1275-1287"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141747854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polychlorinated dibenzo-<i>p</i>-dioxin and dibenzofuran contamination of free-range eggs: estimation of the laying hen's soil ingestion based on a toxicokinetic model, and human consumption recommendations.","authors":"Christelle Oltramare, Markus Zennegg, Mélanie Graille, Sylvain Lerch, Aurélie Berthet, David Vernez","doi":"10.1080/19440049.2024.2384416","DOIUrl":"10.1080/19440049.2024.2384416","url":null,"abstract":"<p><p>Polychlorinated dibenzo-<i>p</i>-dioxins and dibenzofurans (PCDD/Fs) are ubiquitous in the environment. The main route of human exposure is through food consumption. Soil contamination can be problematic for sanitary safety depending on the usage of the soil, such as farming. In case of environmental soil contamination with PCDD/Fs, hen's eggs may be contaminated due to soil ingestion by hens. For this reason, it is important to understand the parameters that influence eggs' contamination when hens are raised in contaminated areas. After the discovery of a contaminated area in Lausanne (Switzerland), we collected hens' eggs from ten domestic-produced eggs and one farm. Based on PCDD/F measurements of eggs and soil, and a toxicokinetic model, we estimated individual hen's soil intake levels and highlighted appropriate parameters to predict the dose ingested. Recommended weekly consumption for home-produced eggs was calculated based on the tolerable weekly intake proposed by EFSA in 2018. The most important parameter to assess the soil ingestion does not seem to be the soil coverage by vegetation but rather the hen's pecking behaviour, the latter being difficult to estimate objectively. For this reason, we recommend using a realistic soil ingestion interval to assess the distribution of egg PCDD/F concentration from free-range hens reared on contaminated soil. The addition of soil contamination in the toxicokinetic model can then be used to recommend to the general population weekly consumption of eggs. The consumption by adults of free-range eggs produced on land with soil containing >90 ng toxic-equivalent (TEQ)/kg dry soil should be avoided. Even with a low level of soil contamination (1-5 ng TEQ/kg dry soil), we would recommend consuming not more than 5 eggs per week for adults and no more than 2 eggs for children below 4 years old.</p>","PeriodicalId":12295,"journal":{"name":"Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment","volume":" ","pages":"1302-1314"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in acrylamide content in selected potato/sweet potato products on the Canadian market.","authors":"Zakir Hossain, Tony Zhao, Adam Becalski, Jakob Schneider, Sherry Yu Feng, Dorothea F K Rawn","doi":"10.1080/19440049.2024.2379388","DOIUrl":"10.1080/19440049.2024.2379388","url":null,"abstract":"<p><p>Processed plant-based foods, particularly high carbohydrate-containing foods, are among the greatest contributors to dietary acrylamide, a probable human carcinogen, uptake. Between 2009 and 2020, five surveys were conducted to determine acrylamide in high carbohydrate-containing foods in Canada. These surveys included sampling of potato and sweet potato chips, French fries, and frozen potato/sweet potato products, as a follow-up to our earlier surveys from 2002 - 2008. Samples were analyzed using isotope dilution (¹³C₃-acrylamide) with LC-MS/MS. The highest mean acrylamide levels were found in sweet potato chips. Among potato chips (57 to 4660 ng g^-1), one brand consistently showed the highest concentrations with wide variability. Acrylamide concentrations decreased over time in ready-to-eat French fries (from 480 to 358 ng g^-1), and one brand showed a clear reduction temporally. Wide variations were observed among brands, among lots/outlets of same brands, and among different food chains. Acrylamide levels in potato chips decreased between 2009 and 2016 (504.3 ng g^-1) relative to the period 2002 - 2008 (1096.9 ng g^-1). The acrylamide trends observed in the products measured in the latest study indicate that food producers may have adopted mitigation strategies.</p>","PeriodicalId":12295,"journal":{"name":"Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment","volume":" ","pages":"1232-1241"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141619788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adulterated dietary supplements commercialized in Brazil: development of a screening method and a preliminary study of cytotoxicity.","authors":"Thaís R Dal Molin, Lauren Pappis, Alencar Kolinski Machado, Géssica Domingos da Silveira, Michele Rorato Sagrillo, Carolina Gonzalez Urquhart, Leandro M de Carvalho, Simone Noremberg, Carine Viana","doi":"10.1080/19440049.2024.2385712","DOIUrl":"10.1080/19440049.2024.2385712","url":null,"abstract":"<p><p>The high consumption of dietary supplements was a fundamental driver for the creation of the regulatory framework by the Brazilian governmental authorities. However, the regulatory agencies lack official low-cost methodologies to evaluate the quality of food supplements. A preliminary screening method by HPLC-DAD was proposed and validated for screening and quantification of adulterants in dietary supplements. The limits of detection and quantification were <0.11 and 0.37 µg.g^-1, respectively. The method was applied for the investigation of ten unauthorized substances (spironolactone, hydrochlorothiazide, furosemide, clenbuterol, testosterone, testosterone propionate, yohimbine, vardenafil, tadalafil, and sildenafil) with a time of analysis of <5 min. Sixteen percent of the 44 samples analyzed had at least one adulterant at or above therapeutic concentrations. Subsequently, <i>in vitro</i> evaluations were performed of the potential cytotoxicity to evaluate the cell viability, DNA damage, determination of nitric oxide levels, and quantification of reactive oxygen species. Despite the necessity of further studies, the results indicate a relationship between the presence of adulterants in food supplements and a potential cytotoxic effect.</p>","PeriodicalId":12295,"journal":{"name":"Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment","volume":" ","pages":"1197-1218"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141859483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduction in mycotoxin levels of African nutmeg (<i>Monodora myristica</i>) powder using a high-energy electron beam.","authors":"Susana E Fiadey, Joyce Agyei-Amponsah, Urszula Gryczka, Evelyn A Otoo, Anita Asamoah, Fidelis C K Ocloo","doi":"10.1080/19440049.2024.2385039","DOIUrl":"10.1080/19440049.2024.2385039","url":null,"abstract":"<p><p>This study investigated the role of irradiation with a high-energy electron beam in reducing mycotoxin levels of African nutmeg powder (ANP) samples. African nutmeg was procured from a local market in Accra, Ghana, cleaned, milled, packaged and irradiated using electrons of energy 9 MeV at doses of 2, 4, 6 and 8 kGy. Un-irradiated ANP served as a control. Mycotoxin levels of the treated samples were determined using appropriate standard methods. Aflatoxins B1 (AFB1) and B2 (AFB2) as well as ochratoxin A (OTA) were detected in the nutmeg samples. Irradiation significantly (<i>p</i> < 0.05) reduced mycotoxin levels of the ANP with increasing doses. Aflatoxins G1 and G2 were not detected in any of the samples. A dose of 8 kGy was effective in reducing the mycotoxin levels below the permissible limit in food. This suggests that a high-energy electron beam is effective in reducing mycotoxin levels in African nutmeg powder.</p>","PeriodicalId":12295,"journal":{"name":"Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment","volume":" ","pages":"1337-1343"},"PeriodicalIF":2.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141859484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}