FEMS yeast research最新文献_第6页

The yeast genome at 30: a blueprint written by a collaborative and consilient community. 30岁时的酵母菌基因组：由协作和和谐的群体所写的蓝图。

IF 3.5 4区生物学

FEMS yeast research Pub Date : 2026-01-05 DOI: 10.1093/femsyr/foag020

Isak S Pretorius, John P Morrissey

{"title":"The yeast genome at 30: a blueprint written by a collaborative and consilient community.","authors":"Isak S Pretorius, John P Morrissey","doi":"10.1093/femsyr/foag020","DOIUrl":"10.1093/femsyr/foag020","url":null,"abstract":"Completion of the Saccharomyces cerevisiae genome sequence three decades ago marked a defining moment in eukaryotic genomics. Beyond a technical milestone, it established a shared reference that transformed how yeast biology is studied, interpreted, and extended across disciplines. This Editorial revisits the yeast genome sequencing project with a focus on the scientific culture that enabled it: an extraordinarily collaborative community willing to coordinate effort, share resources, and collectively tackle biological complexity. That consilient culture proved essential in converting a static DNA sequence into a dynamic framework for discovery, enabling systematic exploration of gene function, cellular organization, and genome-scale biology. As this Special Collection celebrates the 30th anniversary of the yeast genome sequence, we reflect on how shared infrastructure, and collective ambition turned the genome sequences of three related lab strains (S288c and its derivatives FY1679 and AB972) into a lasting platform for innovation. Apart from enabling the field of population genomics and access to the vast genetic diversity of the species, these foundations have facilitated the synthesis and assembly of all 16 chromosomes of the same laboratory strain of S. cerevisiae, bringing the Sc2.0 project within reach of creating the first eukaryotic cell with a fully synthetic genome. This transition-from genome reading to genome writing-positions yeasts as powerful systems for iterative design-build-test-learn cycles and for reimagining genomes of other Saccharomyces and non-Saccharomyces strains (including those used in industry) as highly modifiable biological platforms.","PeriodicalId":12290,"journal":{"name":"FEMS yeast research","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13251884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148005189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimizing carbon-to-nitrogen ratios for enhanced antimicrobial sophorolipid production in Starmerella riodocensis GT-SL1R. 优化碳氮比以提高黑星菌GT-SL1R抗菌皂荚脂产量

IF 3.5 4区生物学

FEMS yeast research Pub Date : 2026-01-05 DOI: 10.1093/femsyr/foag007

Sirawich Sapsirisuk, Pattanan Songdech, Kwanrutai Watchaputi, Panupong Puttarak, Jirayut Euanorasetr, Nitnipa Soontorngun

{"title":"Optimizing carbon-to-nitrogen ratios for enhanced antimicrobial sophorolipid production in Starmerella riodocensis GT-SL1R.","authors":"Sirawich Sapsirisuk, Pattanan Songdech, Kwanrutai Watchaputi, Panupong Puttarak, Jirayut Euanorasetr, Nitnipa Soontorngun","doi":"10.1093/femsyr/foag007","DOIUrl":"10.1093/femsyr/foag007","url":null,"abstract":"Sophorolipids (SLs) are promising biosurfactants with diverse industrial and biomedical applications; however, optimizing their production efficiency remains a challenge. This study investigates the effect of carbon-to-nitrogen (C/N) ratios on SL production by Starmerella riodocensis GT-SL1R and evaluates the antimicrobial and anti-inflammatory properties of partial purified SLs. Among the tested C/N ratios (25-200), the highest SL production (26.71 ± 2.01 g·l⁻¹) was achieved at a C/N of 100, with a yield of 0.27 ± 0.0 g·g⁻¹ after 7 days. High C/N conditions (≥100) upregulated key SL biosynthesis genes (CYP52M1, UgtA1, UgtB1, At, and Sble), supporting enhanced SL production. Scale-up fermentation in a 5 l bioreactor further improved SL production to (55.94 ± 1.17 g·l⁻¹), outperforming Starmerellabombicola BCC5426 (50.49 ± 1.97 g·l⁻¹). Structural characterization revealed a predominance of lactonic SLs. SLs exhibited strong antimicrobial activity against Cutibacterium acnes, Staphylococcus epidermidis and Staphylococcus aureus and demonstrated potent anti-inflammatory effects by inhibiting nitric oxide production (IC50 = 21.93 ± 5.95 µg ml⁻¹), with lower cytotoxicity than indomethacin. These findings highlight S. riodocensis GT-SL1R as a promising candidate for industrial SL production and biomedical applications.","PeriodicalId":12290,"journal":{"name":"FEMS yeast research","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12923171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146124285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Distribution of yeast species and their resistance to copper and sulfite across arboreal and viticulture habitats. 酵母种类分布及其对铜和亚硫酸盐的抗性。

IF 3.5 4区生物学

FEMS yeast research Pub Date : 2026-01-05 DOI: 10.1093/femsyr/foaf074

Justin C Fay, James H Miller, Sofia Dashko, Katie E Hyma, Ping Liu, Helena Volk, Haley Cohen, Nabil F Rahman, Keyang Tang, Emery R Longan, Xueying C Li, Lorena Butinar, Jure Piškur

{"title":"Distribution of yeast species and their resistance to copper and sulfite across arboreal and viticulture habitats.","authors":"Justin C Fay, James H Miller, Sofia Dashko, Katie E Hyma, Ping Liu, Helena Volk, Haley Cohen, Nabil F Rahman, Keyang Tang, Emery R Longan, Xueying C Li, Lorena Butinar, Jure Piškur","doi":"10.1093/femsyr/foaf074","DOIUrl":"10.1093/femsyr/foaf074","url":null,"abstract":"Humans have generated ecological and environmental disturbances, such as vineyards, across the globe. Disturbed environments create widespread and repeated selective pressures that can drive colonization and local adaptation in microbial species. We investigated the distribution of fermentative yeast species in vineyards compared to nearby arboreal habitats and measured their resistance to two commonly used vineyard antimicrobials, copper and sulfite. We analyzed 4 101 strains, representing 70 species, collected from grapevine- and oak-associated substrates at 17 vineyard and 20 non-vineyard sites in the USA and Slovenia. Species frequency varied with geography and substrate, but the majority of species commonly present in vineyards were also found in non-vineyard arboreal environments, representing a potential source for vineyard colonization and exploitation of sugar from grapes. Species varied in both copper and sulfite resistance, but only Saccharomyces cerevisiae showed elevated resistance in vineyard compared to non-vineyard samples. Our results indicate that S. cerevisiae has uniquely taken advantage of vineyard environments through adaptations that appear either unnecessary or inaccessible to other yeast species present in vineyards.","PeriodicalId":12290,"journal":{"name":"FEMS yeast research","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12767201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145767664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A novel method for telomere length detection in fission yeast. 裂变酵母端粒长度检测的新方法。

IF 2.4 4区生物学

FEMS yeast research Pub Date : 2025-01-30 DOI: 10.1093/femsyr/foae040

Hadeel A B Elnaim Mohamed, Hizlan Hincal Agus, Bedia Palabiyik

{"title":"A novel method for telomere length detection in fission yeast.","authors":"Hadeel A B Elnaim Mohamed, Hizlan Hincal Agus, Bedia Palabiyik","doi":"10.1093/femsyr/foae040","DOIUrl":"10.1093/femsyr/foae040","url":null,"abstract":"Fission yeast is the ideal model organism for studying telomere maintenance in higher eukaryotes. Telomere length has been directly correlated with life expectancy and the onset of aging-related diseases in mammals. In this study, we developed a novel simple, and reproducible method to measure the telomere length, by investigating the effect of caffeine and cisplatin on the telomere length in fission yeast. Hydroxyurea-synchronized fission yeast cells were exposed to 62 µM cisplatin and 8.67 mM caffeine treatments for 2 h, then their telomere lengths were evaluated with two different methods. First, the quantitative polymerase chain reaction (qPCR) assay was used as a confirmative method, where telomere length was determined relative to a single-copy gene in the genome. Second, the newly developed method standard polymerase chain reaction (PCR)/ImageJ assay assessed the telomere length based on the amplified PCR band intensity using a set of telomere primers, reflecting telomeric sequence availability in the genome. Both methods show a significant decrease and a notable telomere lengthening in response to cisplatin and caffeine treatments, respectively. The finding supports the accuracy and productivity of the standard PCR/ImageJ assay as it can serve as a quick screening tool to study the effect of suspected chemotherapeutic and antiaging drugs on telomere length in fission yeast.","PeriodicalId":12290,"journal":{"name":"FEMS yeast research","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11781191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reviving Élie Metschnikoff's Monospora: the obligately parasitic yeast Australozyma monospora sp. nov. 复兴Élie Metschnikoff的单孢子菌：专性寄生酵母菌单孢子Australozyma。

IF 3.5 4区生物学

FEMS yeast research Pub Date : 2025-01-30 DOI: 10.1093/femsyr/foaf041

Marc-André Lachance, Carla E Cáceres, Molly J Fredericks, Meghan A Duffy, Tara E Stewart Merrill

{"title":"Reviving Élie Metschnikoff's Monospora: the obligately parasitic yeast Australozyma monospora sp. nov.","authors":"Marc-André Lachance, Carla E Cáceres, Molly J Fredericks, Meghan A Duffy, Tara E Stewart Merrill","doi":"10.1093/femsyr/foaf041","DOIUrl":"10.1093/femsyr/foaf041","url":null,"abstract":"A vast literature explores a model system that consists of a prey crustacean, the water flea Daphnia spp., and an obligately pathogenic yeast that has been referred to as Metschnikowia bicuspidata and thought to represent the material used by Metschnikoff in his study of innate immunity. Typification of species bearing that name and indeed the whole genus has been problematic as regards yeasts that only grow or form aciculate ascospores in hospite. The neotype of M. bicuspidata, unlike the Daphnia parasite, is easily cultured on a variety of laboratory media, although it too can cause serious infections in a variety of mostly aquatic animals. It has become evident that the Daphnia parasite studied by Metschnikoff or current workers is not closely related to M. bicuspidata as currently understood. Analysis of whole genome DNA extracted from the yeast repeatedly found in infected Daphnia specimens shows that it belongs to the recently circumscribed genus Australozyma. The yeast is described here as Australozyma monospora sp. nov. The species, although haplontic and heterothallic, forms single-spored asci without mating. It also appears that all species in the genus are restricted to asexual reproduction, which may explain their rare status. The holotype is MICH 346683. The name is registered in Mycobank under the number MB 859667.","PeriodicalId":12290,"journal":{"name":"FEMS yeast research","volume":"25 ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12359140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thermotolerant yeasts promoting climate-resilient bioproduction. 促进气候适应型生物生产的耐热酵母。

IF 3.5 4区生物学

FEMS yeast research Pub Date : 2025-01-30 DOI: 10.1093/femsyr/foaf047

Roghayeh Shirvani, Maryam Babaei, Motahare Baladi, Matthias G Steiger, Mohammad Barshan-Tashnizi

{"title":"Thermotolerant yeasts promoting climate-resilient bioproduction.","authors":"Roghayeh Shirvani, Maryam Babaei, Motahare Baladi, Matthias G Steiger, Mohammad Barshan-Tashnizi","doi":"10.1093/femsyr/foaf047","DOIUrl":"10.1093/femsyr/foaf047","url":null,"abstract":"The growing challenges posed by global warming and the demand for sustainable food and feed resources underscore the need for robust microbial platforms in bioprocessing. Thermotolerant yeasts have emerged as promising candidates due to their ability to thrive at elevated temperatures and other industrially relevant stresses. This review examines the industrial potential of thermotolerant yeasts in the context of climate change, emphasizing how their resilience can lead to more energy-efficient and cost-effective bioprocesses. Particular attention is paid to the thermodynamic implications of yeast metabolism under heat stress, especially in bioethanol production and methanol metabolism in methylotrophic yeasts, where metabolic heat generation plays a critical role. The cellular and molecular mechanisms underlying thermotolerance are also reviewed, including heat shock sensing mechanisms, the protection of biomolecules, and membrane and cell wall integrity. Advances in genetic and metabolic engineering aimed at enhancing these traits are also highlighted. By integrating current insights into the molecular and cellular mechanisms of thermotolerance, along with recent technological advancements, this review outlines the advantages of high-temperature operations and positions thermotolerant yeasts as vital components of future sustainable bioproduction systems.","PeriodicalId":12290,"journal":{"name":"FEMS yeast research","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolic versatility of the Wickerhamiella/Starmerella yeast clade: from sugar utilization to lipid metabolism. Wickerhamiella/Starmerella酵母分支的代谢多样性：从糖利用到脂质代谢。

IF 3.5 4区生物学

FEMS yeast research Pub Date : 2025-01-30 DOI: 10.1093/femsyr/foaf048

Meriam Vandeputte, Emma Diependaele, Inge Noëlle Adriënne Van Bogaert

{"title":"Metabolic versatility of the Wickerhamiella/Starmerella yeast clade: from sugar utilization to lipid metabolism.","authors":"Meriam Vandeputte, Emma Diependaele, Inge Noëlle Adriënne Van Bogaert","doi":"10.1093/femsyr/foaf048","DOIUrl":"10.1093/femsyr/foaf048","url":null,"abstract":"The Wickerhamiella/Starmerella (W/S) yeast clade has recently gained attention as a \"treasure trove\" of metabolic diversity, characterized by unusual pathways shaped through complex evolutionary events. One of their most distinctive traits is their specialized sugar metabolism, which allows them to thrive in sugar-rich environments. While their role in sugar utilization is well established, emerging evidence suggests that some W/S species can also metabolize hydrophobic compounds, indicating a broader capacity for lipid-related processes. For instance, several W/S species produce sophorolipids (SLs)-a class of glycolipids with commercial applications as sustainable biosurfactants. This ability has sparked growing interest in their potential to synthesize a diverse range of lipids, including glycolipids and dicarboxylic acids. This mini-review explores the evolution and distinctive metabolic features of the W/S clade, focusing not only on its well-characterized sugar metabolism but also on its lesser-known lipid metabolism. Particular attention is given to SL production and the expansion and diversity of cytochrome P450 family 52 enzymes within this underexplored group, emphasizing their biotechnological potential in lipid biosynthesis and their promising applications in sustainable bioprocesses.","PeriodicalId":12290,"journal":{"name":"FEMS yeast research","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12461148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Breeding of yeast strains with intracellular amino acid accumulation for value-added alcoholic beverages. 增值酒精饮料用细胞内氨基酸积累酵母菌的选育。

IF 3.5 4区生物学

FEMS yeast research Pub Date : 2025-01-30 DOI: 10.1093/femsyr/foaf065

Shota Isogai, Akira Nishimura, Hiroshi Takagi

{"title":"Breeding of yeast strains with intracellular amino acid accumulation for value-added alcoholic beverages.","authors":"Shota Isogai, Akira Nishimura, Hiroshi Takagi","doi":"10.1093/femsyr/foaf065","DOIUrl":"10.1093/femsyr/foaf065","url":null,"abstract":"The yeast Saccharomyces cerevisiae converts amino acids into volatile compounds with fruity and floral aromas during fermentation. These amino acid-derived aroma compounds play a critical role in defining the taste and flavor of alcoholic beverages such as sake, beer, and wine. The productivity of amino acid-derived aroma compounds depends on the intracellular availability of their precursor amino acids. Therefore, breeding yeast strains that accumulate amino acids provides a practical approach to developing alcoholic beverages with more unique and attractive sensory characteristics. In this minireview, we describe the isolation of yeast strains that overproduce branched-chain amino acids and phenylalanine, obtained through conventional mutagenesis of industrial brewing yeasts. We also discuss the mechanisms responsible for the increased production of these amino acids in the mutant strains, including altered feedback regulation and transcriptional control of key enzymes involved in their biosynthesis. In addition, we briefly introduce a plasmid-free genome editing system that enables precise modification of metabolic pathways without the integration of foreign DNA, allowing the construction of strains that are not classified as genetically modified organisms. This method represents a promising tool that allows flexible and fine-tuned engineering of yeast metabolic pathways, including the development of strains with tailored aroma profiles.","PeriodicalId":12290,"journal":{"name":"FEMS yeast research","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12604005/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145400254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Functional analysis of Saccharomyces cerevisiae FLO genes through optogenetic control. 酿酒酵母FLO基因的光遗传功能分析。

IF 3.5 4区生物学

FEMS yeast research Pub Date : 2025-01-30 DOI: 10.1093/femsyr/foaf057

Denzel G L Ignacia, Nicole X Bennis, Caitlyn Wheeler, Lylyna C L Tu, Jelle Keijzer, Clara Carqueija Cardoso, Jean-Marc G Daran

{"title":"Functional analysis of Saccharomyces cerevisiae FLO genes through optogenetic control.","authors":"Denzel G L Ignacia, Nicole X Bennis, Caitlyn Wheeler, Lylyna C L Tu, Jelle Keijzer, Clara Carqueija Cardoso, Jean-Marc G Daran","doi":"10.1093/femsyr/foaf057","DOIUrl":"10.1093/femsyr/foaf057","url":null,"abstract":"Flocculation in Saccharomyces cerevisiae is a critical phenotype with ecological and industrial significance. This study aimed to functionally dissect the contributions of individual FLO genes (FLO1, FLO5, FLO9, FLO10, FLO11) to flocculation by employing an optogenetic circuit (OptoQ-AMP5) for precise, light-inducible control of gene expression. A FLO-null platform yeast strain was engineered allowing the expression of individual FLO genes without native background interference. Each FLO gene was reintroduced into the FLO-null background under the control of OptoQ-AMP5. Upon light induction, strains expressing FLO1, FLO5, or FLO10 demonstrated strong flocculation, with FLO1 and FLO5 forming large and structurally distinct aggregates. FLO9 induced a weaker phenotype. Sugar inhibition assays revealed distinct sensitivities among flocculins, notably FLO9's novel sensitivity to fructose and maltotriose. Additionally, FLO-induced changes in cell surface hydrophobicity were quantified, revealing that FLO10 and FLO1 conferred the greatest hydrophobicity, correlating with their aggregation strength. This work establishes a robust platform for investigating flocculation mechanisms in yeast with temporal precision. It highlights the phenotypic diversity encoded within the FLO gene family and their differential responses to environmental cues. The optogenetic system provides a valuable tool for both fundamental studies and the rational engineering of yeast strains for industrial fermentation processes requiring controlled flocculation.","PeriodicalId":12290,"journal":{"name":"FEMS yeast research","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12539575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The advances in creating Crabtree-negative Saccharomyces cerevisiae and the application for chemicals biosynthesis. Crabtree阴性酿酒酵母的制备进展及其在化工生物合成中的应用。

IF 3.5 4区生物学

FEMS yeast research Pub Date : 2025-01-30 DOI: 10.1093/femsyr/foaf014

Yalin Guo, Zhen Xiong, Haotian Zhai, Yuqi Wang, Qingsheng Qi, Jin Hou

引用次数: 0