European Respiratory Journal最新文献

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Sotatercept in Pulmonary Arterial Hypertension - Revolution, Risk, and the Road Ahead. 索特塞普治疗肺动脉高压:革命、风险和未来之路。
IF 21 1区 医学
European Respiratory Journal Pub Date : 2025-08-28 DOI: 10.1183/13993003.01633-2025
Marius M Hoeper
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引用次数: 0
Characterizing research trends in bronchiectasis through AI-powered analytics. 通过人工智能分析描述支气管扩张的研究趋势。
IF 21 1区 医学
European Respiratory Journal Pub Date : 2025-08-28 DOI: 10.1183/13993003.00894-2025
Jayanth Kumar Narayana, Yolanda Koo Wei Ling, Micheál Mac Aogáin, Sanjay H Chotirmall
{"title":"Characterizing research trends in bronchiectasis through AI-powered analytics.","authors":"Jayanth Kumar Narayana, Yolanda Koo Wei Ling, Micheál Mac Aogáin, Sanjay H Chotirmall","doi":"10.1183/13993003.00894-2025","DOIUrl":"https://doi.org/10.1183/13993003.00894-2025","url":null,"abstract":"<p><strong>Background: </strong>Interest in bronchiectasis is increasing and no prior study has used Artificial Intelligence (AI) to interrogate its rich, multidimensional literature to characterize research trends, themes and knowledge gaps.</p><p><strong>Methods: </strong>We reviewed original bronchiectasis research between 1949-2024 (75-year period) to identify, characterize and assess research trends and trajectories using two AI-powered approaches: (1) ATLAS, an AI-topic modelling tool and (2) a custom model, leveraging ChatGPT embedding and text-generation models.</p><p><strong>Results: </strong>AI-powered analytics reveal a nine-fold increase in bronchiectasis research speed since 2000, typified by enhanced richness with four new research topics emerging every five years. Publication trends mirror clinical and technological advances, exemplified by significant rises in computed tomography (CT), microbiome and clinical studies following adoption of HRCT (1970s), next-generation sequencing (2005) and the first clinical guidelines (2008-2010). Topics with sustained growth (<i>i.e.</i> popular) include bronchiectasis-COPD overlap, microbiome-infection, cardiovascular health and exacerbations while those with sudden, short-term increased interest (<i>i.e.</i> trending) focused on microbial pathogens and primary ciliary dyskinesia (PCD) genetics. Mortality represents a nascent topic demonstrating highest year-on-year interest. Growth of research within the \"vicious vortex\" demonstrates thematic imbalance with few studies overlapping with non-vortex components. Evolving research focus toward inflammation is evident, with increased work on comorbidities and quality of life demonstrating a shift from disease- to patient-centric research.</p><p><strong>Conclusion: </strong>AI captures bronchiectasis as a dynamic and interdisciplinary field in continuing growth. Emerging research topics extend beyond the \"vicious-vortex\" framework indicating transition from disease- to patient-centric approaches to optimize clinical care.</p>","PeriodicalId":12265,"journal":{"name":"European Respiratory Journal","volume":" ","pages":""},"PeriodicalIF":21.0,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144948276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Linezolid for the treatment of drug-resistant tuberculosis. 利奈唑胺用于治疗耐药结核病。
IF 24.3 1区 医学
European Respiratory Journal Pub Date : 2025-08-22 DOI: 10.1183/13993003.00927-2025
Christoph Lange,Clifton Barry,Giovanni Sotgiu
{"title":"Linezolid for the treatment of drug-resistant tuberculosis.","authors":"Christoph Lange,Clifton Barry,Giovanni Sotgiu","doi":"10.1183/13993003.00927-2025","DOIUrl":"https://doi.org/10.1183/13993003.00927-2025","url":null,"abstract":"","PeriodicalId":12265,"journal":{"name":"European Respiratory Journal","volume":"15 1","pages":""},"PeriodicalIF":24.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-tuberculosis lung disease: questions and answers. 结核后肺病:问答。
IF 21 1区 医学
European Respiratory Journal Pub Date : 2025-08-22 Print Date: 2025-08-01 DOI: 10.1183/13993003.00992-2025
Giovanni Battista Migliori, Rosella Centis, Lia D'Ambrosio, Denise Rossato Silva, Daria Podlekareva, H Simon Schaaf
{"title":"Post-tuberculosis lung disease: questions and answers.","authors":"Giovanni Battista Migliori, Rosella Centis, Lia D'Ambrosio, Denise Rossato Silva, Daria Podlekareva, H Simon Schaaf","doi":"10.1183/13993003.00992-2025","DOIUrl":"10.1183/13993003.00992-2025","url":null,"abstract":"","PeriodicalId":12265,"journal":{"name":"European Respiratory Journal","volume":" ","pages":""},"PeriodicalIF":21.0,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144559610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
European Respiratory Society and European Sleep Research Society statement on the treatment of central sleep apnoea with adaptive servo-ventilation. 欧洲呼吸学会和欧洲睡眠研究学会关于自适应伺服通气治疗中枢性睡眠呼吸暂停的声明。
IF 21 1区 医学
European Respiratory Journal Pub Date : 2025-08-22 Print Date: 2025-08-01 DOI: 10.1183/13993003.00263-2025
Winfried J Randerath, Sophia E Schiza, Michael Arzt, Maria Rosaria Bonsignore, Raphael Heinzer, Carolina Lombardi, Robert Lyssens, Gianfranco Parati, Thomas Penzel, Jean Louis Pepin, Dirk Pevernagie, Silke Ryan, Luca Vignatelli, Esther I Schwarz
{"title":"European Respiratory Society and European Sleep Research Society statement on the treatment of central sleep apnoea with adaptive servo-ventilation.","authors":"Winfried J Randerath, Sophia E Schiza, Michael Arzt, Maria Rosaria Bonsignore, Raphael Heinzer, Carolina Lombardi, Robert Lyssens, Gianfranco Parati, Thomas Penzel, Jean Louis Pepin, Dirk Pevernagie, Silke Ryan, Luca Vignatelli, Esther I Schwarz","doi":"10.1183/13993003.00263-2025","DOIUrl":"10.1183/13993003.00263-2025","url":null,"abstract":"<p><p>Adaptive servo-ventilation (ASV) has been considered effective in controlling various forms of central sleep apnoea (CSA) and also any additional obstructive sleep apnoea (OSA) component. However, after the publication of the SERVE-HF study, its use was restricted in patients with systolic heart failure (HF) and prevalent CSA, and was withheld from many patients with symptomatic CSA. In the meantime, the devices have been further developed and the algorithms adapted, and there is new evidence from randomised controlled trials and observational studies that makes it necessary to re-evaluate some societies' statements on the use of ASV, especially in patients with HF and CSA and with the current ASV devices. This short statement is based on a review of the effect of ASV on hard cardiovascular end-points, echocardiographic parameters and exercise capacity as well as on sleep architecture and sleep quality, symptoms and quality of life (QoL) in patients with congestive HF. The expert group concludes that ASV has positive effects on CSA and QoL in various forms of CSA, that current ASV devices have no negative effect on hard cardiovascular end-points, and that ASV has positive effects on patient-reported outcomes. Moreover, it is used by Task Force members after optimal treatment of the underlying disease and after an unsuccessful continuous positive airway pressure trial in patients with HF with preserved ejection fraction, but also in patients with left ventricular ejection fraction 30-45%. In the latter group, however, initiation is performed in expert centres only. In severe systolic HF, ASV is sometimes evaluated in a palliative therapy concept for severely symptomatic patients with CSA.</p>","PeriodicalId":12265,"journal":{"name":"European Respiratory Journal","volume":" ","pages":""},"PeriodicalIF":21.0,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply: Use of total correlation and other information-theoretic quantities to describe distributions of clinical datasets, with reference to risk models for pulmonary endarterectomy. 回答:参考肺动脉内膜切除术的风险模型,使用总相关性和其他信息论量来描述临床数据集的分布。
IF 24.3 1区 医学
European Respiratory Journal Pub Date : 2025-08-22 DOI: 10.1183/13993003.01198-2025
James Liley,Katherine Bunclark,Mark Toshner
{"title":"Reply: Use of total correlation and other information-theoretic quantities to describe distributions of clinical datasets, with reference to risk models for pulmonary endarterectomy.","authors":"James Liley,Katherine Bunclark,Mark Toshner","doi":"10.1183/13993003.01198-2025","DOIUrl":"https://doi.org/10.1183/13993003.01198-2025","url":null,"abstract":"","PeriodicalId":12265,"journal":{"name":"European Respiratory Journal","volume":"19 1","pages":""},"PeriodicalIF":24.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiopulmonary exercise testing unmasks right ventricular failure in pulmonary arterial hypertension risk stratification: time to reframe the role of the 6-minute walk test? 心肺运动试验揭示肺动脉高压风险分层中的右心衰:是时候重新定义6分钟步行试验的作用了?
IF 24.3 1区 医学
European Respiratory Journal Pub Date : 2025-08-22 DOI: 10.1183/13993003.00849-2025
Andrew Constantine,Konstantinos Dimopoulos,Colm McCabe
{"title":"Cardiopulmonary exercise testing unmasks right ventricular failure in pulmonary arterial hypertension risk stratification: time to reframe the role of the 6-minute walk test?","authors":"Andrew Constantine,Konstantinos Dimopoulos,Colm McCabe","doi":"10.1183/13993003.00849-2025","DOIUrl":"https://doi.org/10.1183/13993003.00849-2025","url":null,"abstract":"","PeriodicalId":12265,"journal":{"name":"European Respiratory Journal","volume":"24 1","pages":""},"PeriodicalIF":24.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beyond predictive accuracy: interpreting feature importances in pulmonary endarterectomy risk models with total correlation analysis. 超越预测准确性:用全相关分析解释肺内膜切除术风险模型中特征的重要性。
IF 24.3 1区 医学
European Respiratory Journal Pub Date : 2025-08-22 DOI: 10.1183/13993003.00893-2025
Yoshiyasu Takefuji
{"title":"Beyond predictive accuracy: interpreting feature importances in pulmonary endarterectomy risk models with total correlation analysis.","authors":"Yoshiyasu Takefuji","doi":"10.1183/13993003.00893-2025","DOIUrl":"https://doi.org/10.1183/13993003.00893-2025","url":null,"abstract":"","PeriodicalId":12265,"journal":{"name":"European Respiratory Journal","volume":"9 1","pages":""},"PeriodicalIF":24.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adaptive servo-ventilation for central sleep apnoea in heart failure: where are we? 自适应伺服通气治疗心力衰竭中枢性睡眠呼吸暂停:进展如何?
IF 24.3 1区 医学
European Respiratory Journal Pub Date : 2025-08-22 DOI: 10.1183/13993003.00976-2025
Patrick Lévy
{"title":"Adaptive servo-ventilation for central sleep apnoea in heart failure: where are we?","authors":"Patrick Lévy","doi":"10.1183/13993003.00976-2025","DOIUrl":"https://doi.org/10.1183/13993003.00976-2025","url":null,"abstract":"","PeriodicalId":12265,"journal":{"name":"European Respiratory Journal","volume":"4 1","pages":""},"PeriodicalIF":24.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Just like good wine, European bronchiectasis deserves regional denominations. 就像好酒一样,欧洲的支气管扩张也应该有地区名称。
IF 24.3 1区 医学
European Respiratory Journal Pub Date : 2025-08-22 DOI: 10.1183/13993003.01020-2025
Keshav Mangalick,Leopoldo N Segal
{"title":"Just like good wine, European bronchiectasis deserves regional denominations.","authors":"Keshav Mangalick,Leopoldo N Segal","doi":"10.1183/13993003.01020-2025","DOIUrl":"https://doi.org/10.1183/13993003.01020-2025","url":null,"abstract":"","PeriodicalId":12265,"journal":{"name":"European Respiratory Journal","volume":"16 1","pages":""},"PeriodicalIF":24.3,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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