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We also CanFly! The 2nd MexFly drosophila research conference 我们也会飞!第二届墨西哥果蝇研究会议

IF 1.2 4区生物学

Fly Pub Date : 2017-01-09 DOI: 10.1080/19336934.2016.1271517

F. Missirlis, M. Nahmad

引用次数: 0

How tissue damage MET metabolism: Regulation of the systemic damage response. 如何组织损伤MET代谢:调节全身损伤反应。

IF 1.2 4区生物学

Fly Pub Date : 2017-01-02 Epub Date: 2016-08-11 DOI: 10.1080/19336934.2016.1221549

Soshiro Kashio, Fumiaki Obata, Masayuki Miura

引用次数: 3

Drosophila yakuba mayottensis, a new model for the study of incipient ecological speciation. 雅库巴马约特果蝇:早期生态物种形成研究的新模式。

IF 1.2 4区生物学

Fly Pub Date : 2017-01-02 Epub Date: 2016-08-11 DOI: 10.1080/19336934.2016.1221550

Amir Yassin

{"title":"Drosophila yakuba mayottensis, a new model for the study of incipient ecological speciation.","authors":"Amir Yassin","doi":"10.1080/19336934.2016.1221550","DOIUrl":"https://doi.org/10.1080/19336934.2016.1221550","url":null,"abstract":"A full understanding of how ecological factors drive the fixation of genetic changes during speciation is obscured by the lack of appropriate models with clear natural history and powerful genetic toolkits. In a recent study, we described an early stage of ecological speciation in a population of the generalist species Drosophila yakuba (melanogaster subgroup) on the island of Mayotte (Indian Ocean). On this island, flies are strongly associated with the toxic fruits of noni (Morinda citrifolia) and show a partial degree of pre-zygotic reproductive isolation. Here, I mine the nuclear and mitochondrial genomes and provide a full morphological description of this population. Only 29 nuclear sites (< 4 × 10-7 of the genome) are fixed in this population and absent from 3 mainland populations and the closest relative D. santomea, but no mitochondrial or morphological character distinguish Mayotte flies from the mainland. This result indicates that physiological and behavioral traits may evolve faster than morphology at the early stages of speciation. Based on these differences, the Mayotte population is designated as a new subspecies, Drosophila yakuba mayottensis subsp. nov., and its strong potential in understanding the genetics of speciation and plant-insect interactions is discussed.","PeriodicalId":12128,"journal":{"name":"Fly","volume":"11 1","pages":"37-45"},"PeriodicalIF":1.2,"publicationDate":"2017-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19336934.2016.1221550","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34389019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

The beneficial role of extracellular reactive oxygen species in apoptosis-induced compensatory proliferation. 细胞外活性氧在凋亡诱导的代偿性增殖中的有益作用。

IF 1.2 4区生物学

Fly Pub Date : 2017-01-02 Epub Date: 2016-08-15 DOI: 10.1080/19336934.2016.1222997

Neha Diwanji, Andreas Bergmann

{"title":"The beneficial role of extracellular reactive oxygen species in apoptosis-induced compensatory proliferation.","authors":"Neha Diwanji, Andreas Bergmann","doi":"10.1080/19336934.2016.1222997","DOIUrl":"https://doi.org/10.1080/19336934.2016.1222997","url":null,"abstract":"Apoptosis-induced proliferation (AiP) maintains tissue homeostasis following massive stress-induced cell death. During this phenomenon, dying cells induce proliferation of the surviving cells to compensate for the tissue loss, and thus restore organ size. Along with wound healing and tissue regeneration, AiP also contributes to tumor repopulation following radiation or chemotherapy. There are several models of AiP. Using an \"undead\" AiP model that causes hyperplastic overgrowth of Drosophila epithelial tissue, we recently demonstrated that extracellular reactive oxygen species (eROS) are produced by undead epithelial cells, and are necessary for inducing AiP and overgrowth. Furthermore, hemocytes, the Drosophila blood cells, are seen adjacent to the undead epithelial tissue, and may secrete the TNF ortholog Eiger that signals through the TNF receptor to active Jun-N-terminal kinase (JNK) in the undead tissue and induce proliferation. We propose that undead epithelial tissue triggers an inflammatory response that resembles recruitment of macrophages to human epithelial tumors, and that these tumor-associated macrophages release signals for proliferation and tumor growth of the epithelium. This Extra View article summarizes these recent findings with a focus on the role of eROS for promoting regeneration and inflammation-induced tumorigenesis.","PeriodicalId":12128,"journal":{"name":"Fly","volume":"11 1","pages":"46-52"},"PeriodicalIF":1.2,"publicationDate":"2017-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19336934.2016.1222997","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34347642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 28

From the editors 来自编辑

IF 1.2 4区生物学

Fly Pub Date : 2017-01-02 DOI: 10.1080/19336934.2016.1276793

Blandine Lapercheis

引用次数: 0

Dpr-DIP matching expression in Drosophila synaptic pairs. 果蝇突触对中dprp - dip匹配表达。

IF 1.2 4区生物学

Fly Pub Date : 2017-01-02 Epub Date: 2016-07-22 DOI: 10.1080/19336934.2016.1214784

Marta Morey

{"title":"Dpr-DIP matching expression in Drosophila synaptic pairs.","authors":"Marta Morey","doi":"10.1080/19336934.2016.1214784","DOIUrl":"https://doi.org/10.1080/19336934.2016.1214784","url":null,"abstract":"Neurons form precise patterns of connections. The cellular recognition mechanisms regulating the selection of synaptic partners are poorly understood. As final mediators of cell-cell interactions, cell surface and secreted molecules (CSMs) are expected to play important roles in this process. To gain insight into how neurons discriminate synaptic partners, we profiled the transcriptomes of 7 closely related neurons forming distinct synaptic connections in discrete layers in the medulla neuropil of the fly visual system. Our sequencing data revealed that each one of these neurons expresses a unique combination of hundreds of CSMs at the onset of synapse formation. We show that 21 paralogs of the defective proboscis extension response (Dpr) family are expressed in a unique cell-type-specific fashion, consistent with the distinct connectivity pattern of each neuron profiled. Expression analysis of their cognate binding partners, the 9 members of the Dpr interacting protein (DIP) family, revealed complementary layer-specific expression in the medulla, suggestive of interactions between neurons expressing Dpr and those expressing DIP in the same layer. Through coexpression analysis and correlation to connectome data, we identify neurons expressing DIP as a subset of the synaptic partners of the neurons expressing Dpr. We propose that Dpr-DIP interactions regulate patterns of connectivity between the neurons expressing them.","PeriodicalId":12128,"journal":{"name":"Fly","volume":"11 1","pages":"19-26"},"PeriodicalIF":1.2,"publicationDate":"2017-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19336934.2016.1214784","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34698462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Tools and strategies for scarless allele replacement in Drosophila using CRISPR/Cas9. 利用 CRISPR/Cas9 在果蝇中实现无痕等位基因替换的工具和策略。

IF 1.2 4区生物学

Fly Pub Date : 2017-01-02 Epub Date: 2016-08-05 DOI: 10.1080/19336934.2016.1220463

Abigail M Lamb, Elizabeth A Walker, Patricia J Wittkopp

引用次数: 0

The translation factors of Drosophila melanogaster. 黑腹果蝇的翻译因子。

IF 1.2 4区生物学

Fly Pub Date : 2017-01-02 Epub Date: 2016-08-05 DOI: 10.1080/19336934.2016.1220464

Steven J Marygold, Helen Attrill, Paul Lasko

引用次数: 15

Infection avoidance behavior: Viral exposure reduces the motivation to forage in female Drosophila melanogaster. 感染回避行为:病毒暴露降低雌性黑腹果蝇觅食的动机。

IF 1.2 4区生物学

Fly Pub Date : 2017-01-02 Epub Date: 2016-06-30 DOI: 10.1080/19336934.2016.1207029

Pedro F Vale, Michael D Jardine

引用次数: 28

Ectoparasitic mites and their Drosophila hosts. 外寄生螨及其寄主果蝇。

IF 1.2 4区生物学

Fly Pub Date : 2017-01-02 Epub Date: 2016-08-19 DOI: 10.1080/19336934.2016.1222998

Alejandra Perez-Leanos, Mariana Ramirez Loustalot-Laclette, Nestor Nazario-Yepiz, Therese Ann Markow

{"title":"Ectoparasitic mites and their Drosophila hosts.","authors":"Alejandra Perez-Leanos, Mariana Ramirez Loustalot-Laclette, Nestor Nazario-Yepiz, Therese Ann Markow","doi":"10.1080/19336934.2016.1222998","DOIUrl":"https://doi.org/10.1080/19336934.2016.1222998","url":null,"abstract":"Only two parasite interactions are known for Drosophila to date: Allantonematid nematodes associated with mycophagous Drosophilids and the ectoparasitic mite Macrocheles subbadius with the Sonoran Desert endemic Drosophila nigrospiracula. Unlike the nematode-Drosophila association, breadth of mite parasitism on Drosophila species is unknown. As M. subbadius is a generalist, parasitism of additional Drosophilids is expected. We determined the extent and distribution of mite parasitism in nature Drosophilids collected in Mexico and southern California. Thirteen additional species of Drosophilids were infested. Interestingly, 10 belong to the repleta species group of the subgenus Drosophila, despite the fact that the majority of flies collected were of the subgenus Sophophora. In all cases but 2, the associated mites were M. subbadius. Drosophila hexastigma was found to have not only M. subbadius, but another Mesostigmatid mite, Paragarmania bakeri, as well. One D. hydei was also found to have a mite from genus Lasioseius attached. In both choice and no-choice experiments, mites were more attracted to repleta group species than to Sophophoran. The extent of mite parasitism clearly is much broader than previously reported and suggests a host bias mediated either by mite preference and/or some mechanism of resistance in particular Drosophilid lineages.","PeriodicalId":12128,"journal":{"name":"Fly","volume":"11 1","pages":"10-18"},"PeriodicalIF":1.2,"publicationDate":"2017-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19336934.2016.1222998","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34319948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16