IF 2.8 3区医学

Eye Pub Date : 2024-09-19 DOI: 10.1038/s41433-024-03354-0

Robert McGrath, Edward Ahern, Mark James, Zubair Idrees, Eamonn O'Connell

{"title":"Ophthalmology inpatient consultations: an Irish tertiary hospital experience.","authors":"Robert McGrath, Edward Ahern, Mark James, Zubair Idrees, Eamonn O'Connell","doi":"10.1038/s41433-024-03354-0","DOIUrl":"https://doi.org/10.1038/s41433-024-03354-0","url":null,"abstract":"<p><strong>Background: </strong>Ophthalmology consultation on inpatients is often important to optimise eye care and provide information for referring teams. Inpatient consultation may constitute a not-insignificant workload however. This study reports on the nature and necessity of ophthalmology inpatient consults in a large Irish hospital.</p><p><strong>Methods: </strong>Retrospective analysis of all consecutive ophthalmology inpatient consultations over a 12-month period.</p><p><strong>Results: </strong>In total, 359 consult requests were received primarily from adult medicine (57.9%), surgery (22%) and paediatric teams (18.4%). The most common reasons for referral were loss of vision (23.7%); visual field testing (15%); diplopia or abnormal eye movements (11.4%); and screening for ocular features of systemic disease (10.6%). Presumptive diagnoses by referring teams were correct in 29.5% of cases. The majority had normal eye examinations (53.2%) or non-sight-threatening features (16.8%), while a minority had acute eye pathology (30%). Most patients (80.4%) required no intervention. A minority required medical (12.5%), orthoptic (4.6%) or surgical (2.4%) intervention. The majority of patients (81%) were fit for transfer to the eye clinic and did not require bedside examination.</p><p><strong>Conclusions: </strong>Our study found a high proportion of ophthalmology inpatient consultations had normal eye exams and required no intervention. The quality of referrals was variable suggesting that clearer guidelines and more ophthalmology education is needed for referring teams.</p>","PeriodicalId":12125,"journal":{"name":"Eye","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pneumatic displacement of submacular haemorrhage secondary to neovascular age-related macular degeneration and polypoidal choroidal vasculopathy 继发于新生血管性老年黄斑变性和多形性脉络膜血管病的白斑下出血的气动移位

IF 3.9 3区医学

Eye Pub Date : 2024-09-19 DOI: 10.1038/s41433-024-03318-4

Shaun Sebastian Sim, Kai Xiong Cheong, Hiok Hong Chan, Jessica Qian Hui Choo, Andrew S. H. Tsai, Shu Yen Lee, Ian Yew San Yeo, Chui Ming Gemmy Cheung, Kelvin Yi Chong Teo

{"title":"Pneumatic displacement of submacular haemorrhage secondary to neovascular age-related macular degeneration and polypoidal choroidal vasculopathy","authors":"Shaun Sebastian Sim, Kai Xiong Cheong, Hiok Hong Chan, Jessica Qian Hui Choo, Andrew S. H. Tsai, Shu Yen Lee, Ian Yew San Yeo, Chui Ming Gemmy Cheung, Kelvin Yi Chong Teo","doi":"10.1038/s41433-024-03318-4","DOIUrl":"https://doi.org/10.1038/s41433-024-03318-4","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Background</h3><p>To compare the visual and anatomical outcomes of pneumatic displacement (PD) combined with anti-vascular endothelial growth factor (VEGF) therapy versus anti-VEGF monotherapy in treatment-naive eyes with submacular haemorrhage (SMH) secondary to neovascular age-related macular degeneration and polypoidal choroidal vasculopathy.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>In a retrospective comparative interventional study of 57 eyes, the changes in logMAR visual acuity (VA), and SMH height and area at baseline at months 1, 3 and 12 were compared between the PD and non-PD groups.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>There was no significant difference in mean VA in the PD versus non-PD group at month 12 (1.1 versus 0.7, <i>p</i> = 0.09). At baseline, the PD group, compared to the non-PD group, had significantly larger SMH area (35.9 versus 26.9 mm<sup>2</sup>, <i>p</i> = 0.04) and SMH height at the fovea (733.7 versus 503.6 µm, <i>p</i> < 0.01). The greatest reduction in SMH height and area occurred between baseline and month 1 in the PD group, which was faster than between month 1 and month 3 in the non-PD group, with similar findings in the matched pair analysis matched for SMH height and area. In the multivariable analysis, only baseline VA was associated with VA outcomes (month 1: <i>β</i> = −0.46, 95% [confidence interval] CI = −0.78 to −0.14, <i>p</i> = 0.006; month 3: <i>β</i> = −0.52, 95% CI = −0.86 to −0.18, <i>p</i> = 0.004; and month 12: <i>β</i> = −0.78, 95% CI = −1.16 to −0.39, <i>p</i> < 0.001).</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>The visual outcome of SMH at month 12 in nAMD and PCV is poor regardless of whether PD is performed in addition to anti-VEGF therapy, although a more rapid resolution of SMH can be expected.</p>","PeriodicalId":12125,"journal":{"name":"Eye","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142268898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Between Scylla and Charybdis?—Health insurance claims-data to monitor quality of service delivery in ophthalmology 在 Scylla 和 Charybdis 之间？-用于监测眼科服务质量的医疗保险索赔数据

IF 3.9 3区医学

Eye Pub Date : 2024-09-18 DOI: 10.1038/s41433-024-03333-5

Martin K. Schmid, Dawn A. Sim, Stefan Boes, Thomas J. Wolfensberger, Lucas M. Bachmann, Katja Hatz, Michael A. Thiel

{"title":"Between Scylla and Charybdis?—Health insurance claims-data to monitor quality of service delivery in ophthalmology","authors":"Martin K. Schmid, Dawn A. Sim, Stefan Boes, Thomas J. Wolfensberger, Lucas M. Bachmann, Katja Hatz, Michael A. Thiel","doi":"10.1038/s41433-024-03333-5","DOIUrl":"https://doi.org/10.1038/s41433-024-03333-5","url":null,"abstract":"The seminal work of Wennberg and Gittelsohn in 1973 emphasised the importance of health information for informed decision-making. This led to the creation of the Dartmouth Health Atlas in 1996, which has become an important resource for monitoring health services in the USA. The Dartmouth Health Atlas research revealed the existence of variation in health care without benefit to patients, and the dependence of health care use on local resource supply. Similar initiatives emerged around the world, from the UK to Asia. The availability of administrative data has become essential for evaluating health service delivery and for informing health economic analysis and policy decisions. Access to data depends on the organisation of the health system, with more centralised systems facilitating comprehensive data collection. We contrast the decentralised structure of the Swiss healthcare system with that of the US and the UK, and highlight the challenges of harmonising data for nationwide health monitoring. The example of optical coherence tomography (OCT) in Swiss ophthalmology illustrates the variability in care practices and billing patterns. This variability can be attributed to the lack of clear guidelines and the complexity of billing codes. Incentives to charge incorrect rates influence billing, adding a further variance component to the variance in care that cannot be subtracted from the total variance at the level of a health insurance fund and distorting the results. In certain environments the quality of data on care is so variable that a sound conclusions for health policy decisions represent a great challenge.","PeriodicalId":12125,"journal":{"name":"Eye","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142254139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The central retina vessel density and foveal avascular zone values of 792 healthy adults using optical coherence tomography angiography 利用光学相干断层血管造影测量 792 名健康成年人的视网膜中央血管密度和眼窝血管带值

IF 3.9 3区医学

Eye Pub Date : 2024-09-18 DOI: 10.1038/s41433-024-03320-w

Hamid Reza Heidarzadeh, Mojtaba Abrishami, Elaheh Ebrahimi Miandehi, Nasser Shoeibi, Mohammad Reza Ansari Astaneh, Seyedeh Maryam Hosseini, Majid Abrishami, Saeed Eslami, Ali Bolouki

{"title":"The central retina vessel density and foveal avascular zone values of 792 healthy adults using optical coherence tomography angiography","authors":"Hamid Reza Heidarzadeh, Mojtaba Abrishami, Elaheh Ebrahimi Miandehi, Nasser Shoeibi, Mohammad Reza Ansari Astaneh, Seyedeh Maryam Hosseini, Majid Abrishami, Saeed Eslami, Ali Bolouki","doi":"10.1038/s41433-024-03320-w","DOIUrl":"https://doi.org/10.1038/s41433-024-03320-w","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Background/objectives</h3><p>To determine normal macular vessel density (VD) and foveal avascular zone (FAZ) values using optical coherence tomography angiography (OCTA) analysis in healthy adults.</p><h3 data-test=\"abstract-sub-heading\">Subjects/methods</h3><p>As part of the Prospective Epidemiological Research Studies in Iran (PERSIAN) Organizational Cohort study at Mashhad University of Medical Sciences (POCM), we conducted a cross-sectional study using 3 × 3 and 6 × 6 mm OCTA scans to evaluate the VD of the macular superficial capillary plexus (SCP), deep capillary plexus (DCP), and the FAZ area in healthy adults.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>The study included 792 participants, with a mean age of 39.8 ± 6.8 years. There were 359 males with a mean age of 39.9 ± 7.8 years and 440 females with a mean age of 39.4 ± 6 years. The mean values of various parameters were measured, including the right eye whole image SCP and DCP VDs, FAZ area, FAZ perimeter, and fovea VD in a 300 µm wide zone around FAZ (FD). These values were found to be 45.9 ± 2.6%, 50.2 ± 3%, 0.3 ± 0.1mm<sup>2</sup>, 2.1 ± 0.4 mm, and 50.4 ± 3.3%, respectively. Females and younger participants had significantly higher mean values of whole image SCP and DCP VDs. Additionally, all FAZ parameters had significantly higher values in females, while younger participants had significantly higher mean FD values. Simple linear regression analyses showed that age was negatively correlated with right eye SCP and DCP VDs.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>Our study established standard SCP and DCP VD values influenced by age and gender. Age correlates negatively with both, DCP VDs correlate negatively with height and weight, and SCP VDs correlate positively with diastolic blood pressure.</p>","PeriodicalId":12125,"journal":{"name":"Eye","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142254145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations of static and dynamic iris parameters in healthy Chinese individuals: the Handan Eye Study 中国健康人虹膜静态和动态参数的关联：邯郸眼科研究

IF 3.9 3区医学

Eye Pub Date : 2024-09-18 DOI: 10.1038/s41433-024-03345-1

Jin Wang, Tingting Liu, Sizhen Li, Mingguang He, Xiaofei Wang, Ningli Wang, Ye Zhang

{"title":"Associations of static and dynamic iris parameters in healthy Chinese individuals: the Handan Eye Study","authors":"Jin Wang, Tingting Liu, Sizhen Li, Mingguang He, Xiaofei Wang, Ningli Wang, Ye Zhang","doi":"10.1038/s41433-024-03345-1","DOIUrl":"https://doi.org/10.1038/s41433-024-03345-1","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>To determine the associations between the demographic factors (age and sex) and physiological dynamic iris changes and explore the associated factors for iris cross-sectional area (IA) change in healthy Chinese individuals.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>This cross-sectional study included individuals aged ≥40 years with an open angle and underwent anterior segment optical coherence tomography under light and dark conditions from the follow-up cohort of the Handan Eye Study. Ocular data from the right eye were analyzed. The Pearson correlation coefficient was used to assess the relationship between age and iris parameters, including iris thickness (IT), IA, and iris curvature (IC), as well as the pupil diameter (PD) in the dark, and their changes from light to dark conditions. Linear regression analysis was performed to identify the potential factors associated with IA change.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>The final analysis included 465 healthy individuals. PD in dark, IA change and PD change decreased with age (<i>P</i> < 0.001), whereas IC increased with age (<i>P</i> < 0.001). IT and IT change were smaller, and IC was larger in women than that in men (<i>P</i> = 0.021, 0.007, and 0.010, respectively). Older age (<i>P</i> = 0.041), larger lens thickness (<i>P</i> = 0.013), larger IC change (<i>P</i> < 0.001), and smaller PD change (<i>P</i> < 0.001) were significantly associated with a smaller IA change.</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>Our study demonstrated the associations of static and dynamic iris parameters in healthy Chinese individuals. The findings provided a possible explanation for the higher prevalence of primary angle closure disease in elderly and female populations.</p>","PeriodicalId":12125,"journal":{"name":"Eye","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142254118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Infographic: ranibizumab or bevacizumab treat & extend for neovascular age-related macular degeneration (AMD): LUCAS trial 信息图表：雷尼珠单抗或贝伐单抗治疗和延长新生血管性年龄相关性黄斑变性 (AMD) 的疗程：LUCAS 试验

IF 3.9 3区医学

Eye Pub Date : 2024-09-18 DOI: 10.1038/s41433-024-03339-z

Ishani Barai, Sobha Sivaprasad, Christin Henein

引用次数: 0

Infographic: The port delivery system with ranibizumab for neovascular age-related macular degeneration: LADDER trial 信息图：使用雷尼珠单抗治疗新生血管性老年黄斑变性的端口给药系统：LADDER试验

IF 3.9 3区医学

Eye Pub Date : 2024-09-18 DOI: 10.1038/s41433-024-03337-1

Ishani Barai, Sobha Sivaprasad, Christin Henein

引用次数: 0

Haab’s striae sans buphthalmos 无眼球的哈氏条纹

IF 3.9 3区医学

Eye Pub Date : 2024-09-18 DOI: 10.1038/s41433-024-03310-y

Toshit Varshney, Arnav Panigrahi, Abhishek Singh, Viney Gupta, Shikha Gupta

引用次数: 0

Comment on: “Herpes Zoster in neuro-ophthalmology: a practical approach” 评论"神经眼科中的带状疱疹：实用方法

IF 3.9 3区医学

Eye Pub Date : 2024-09-18 DOI: 10.1038/s41433-024-03350-4

Duncan Marston, Sara Xuereb

{"title":"Comment on: “Herpes Zoster in neuro-ophthalmology: a practical approach”","authors":"Duncan Marston, Sara Xuereb","doi":"10.1038/s41433-024-03350-4","DOIUrl":"https://doi.org/10.1038/s41433-024-03350-4","url":null,"abstract":"<p>We have read with great interest the recent article by Tao et al. [1] which provides the reader with a concise overview regarding the neuro-ophthalmic manifestations of herpes zoster and their management. However, we would like to make a comment regarding what in our opinion is a clinical misinterpretation of Hutchinson’s sign as a predictor of neuro-ophthalmic disease.</p><p>In 1866, Sir Jonathan Hutchinson documented “My cases <i>[n</i> = <i>13]</i> are as yet too few in number to authorize a confident statement, but thus far I have never seen the whole side of the nose affected without also witnessing inflammation of the eye and I have never seen the eye inflame unless the side of the nose showed vesicles.” [2]. A prospective study carried out by Adam et al. [3] did not find any statistical significance between Hutchinson’s sign (nasociliary nerve involvement) and herpes zoster ophthalmicus (p = 0.184). However, statistical significance was approached when Hutchinson’s sign coexisted with blepharitis and conjunctivitis (p = 0.067). Furthermore, supratrocheal nerve involvement showed greater statistical significance (pvalue = 0.0004) for the development of herpes zoster ophthalmicus, whilst having a positive predictive value of 0.6 and a negative predictive value of 0.89 for associated eye involvement [3].</p>","PeriodicalId":12125,"journal":{"name":"Eye","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142254140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the unexplored: identifying knowledge gaps in novel pharmacological treatments for diabetic retinopathy 探索未知领域：确定糖尿病视网膜病变新型药理疗法的知识差距

IF 3.9 3区医学

Eye Pub Date : 2024-09-17 DOI: 10.1038/s41433-024-03349-x

Amin Sharifan, Sobha Sivaprasad

引用次数: 0

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